# APLB Glutathione Niacinamide Ampoule Serum for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [APLB](https://lovi.care/skincare/ca/brands/aplb)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Highly suitable for your oily skin, this serum contains Melaleuca Alternifolia Tree Leaf Extract and Niacinamide to help regulate sebum and reduce inflammation, addressing your primary concern of oily shine.
- The inclusion of niacinamide and ascorbic acid offers moderate brightening and evening of skin tone, providing general skincare benefits that support overall skin health.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing Centella Asiatica Extract and Dipotassium Glycyrrhizate.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-acne-prone-skin): High

## Key ingredients

Glutathione, Niacinamide, Centella Asiatica Extract, Sodium Hyaluronate, Squalane

## What the research says

- Topical application of 100% tea tree oil significantly reduced histamine-induced mean weal volume compared to control in twenty-seven volunteers. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Based on a very large amount of data, users with sensitive, acne-prone, and combination skin frequently praise this serum for its lightweight, non-sticky hydration and ability to calm redness while gradually evening out skin tone. While it effectively delivers a "glass skin" glow and smooths texture, many users note that brightening hyperpigmentation is a slow process requiring consistent long-term use.

- Liked: Lightweight & absorbent (mostly mentioned)
- Liked: Brightens skin tone (often mentioned)
- Liked: Soothes sensitive skin (often mentioned)
- Liked: Hydrating & plumping (sometimes noted)
- Disliked: Slow visible results (sometimes noted)
- Disliked: Cheap packaging feel (rarely noted)
- Disliked: Insufficient for dryness (rarely noted)
- Disliked: Rare skin irritation (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does APLB Glutathione Niacinamide Ampoule Serum work for oily skin?

This serum works well for oily skin by helping control shine and calm irritation, though other products fit this skin type even better. To provide a top fit for oily skin, a product of this type needs ingredients that regulate oil and reduce pores, such as zinc PCA and ceramides, alongside lightweight hydration that keeps the skin comfortable.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this serum a good fit for oily skin?

This serum fits your oily skin well because it contains niacinamide and tea tree leaf extract to help control oil and reduce redness. Oily skin of this type also benefits from ingredients like zinc pca and balancing ceramides to manage shine and pores more effectively.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Glutathione do for oily skin?

Glutathione helps protect oily skin from everyday damage and oxidative stress. It may also help keep your skin looking bright and smooth.
Sources: [Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/)

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for oily skin?

This serum goes in your evening routine as a treatment step after cleansing and toning. Oily skin typically needs a treatment with lightweight ingredients like tea tree extract and niacinamide to help control shine and soothe irritation.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to calm and hydrate your skin, followed by your retinol treatment. This approach is unlikely to cause irritation because the formula includes soothing ingredients like Centella Asiatica Extract.

### How often should I use this serum?

This serum works well in your evening routine, but an average fit for your oily skin needs a product that provides oil control and lightweight hydration with ingredients like niacinamide and Centella Asiatica extract.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to cause breakouts or clog pores on oily skin because it has an excellent safety profile without harsh ingredients and includes soothing extracts. Oily skin works best with lightweight, oil-balancing ingredients like tea tree extract and niacinamide to keep pores clear and calm.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/oily-skin) — High fit — CA$27.99 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/oily-skin) — High fit — CA$24.44 at Amazon
- [ANUA PEACH 70% NIACINAMIDE SERUM](https://lovi.care/skincare/ca/p/anua/peach-70-niacinamide-serum/for/oily-skin) — High fit — CA$33.50 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — CA$20.96 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — CA$37.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ca/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — CA$29.98 at Amazon

## Where to buy

- Amazon.ca: CA$21.99 (https://www.amazon.ca/dp/B0C2P4LLXX?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Centella Asiatica Extract, Butylene Glycol, Propanediol, Glycerin, Diethoxyethyl Succinate, Panthenol, Sodium Hyaluronate, Allantoin, Sodium Polyacryloyldimethyl Taurate, Glyceryl Acrylate Acrylic Acid Copolymer, Nelumbo Nucifera Extract, Artemisia Annua Extract, Rice Extract, Saccharomyces Ferment, Solanum Melongena Fruit Extract, Melaleuca Alternifolia Tree Leaf Extract, Hydrolyzed Collagen, Squalane, Beta-Glucan, Ascorbic Acid, Dipropylene Glycol, Hippophae Rhamnoides Fruit Extract, Adenosine, Madecassic Acid, Asiaticoside, Asiatic Acid, Caprylic Capric Triglyceride, Hydrogenated Lecithin, Glyceryl Stearate, Cholesterol, Styrene Acrylates Copolymer, Cellulose Gum, Xanthan Gum, Inulin, Cellulose, Glucose, Fructose, Citric Acid, Disodium Edta, Hydroxyacetophenone, 1,2-Hexanediol, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Sodium Citrate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin (this page)
- Australia: https://lovi.care/skincare/au/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/aplb/glutathione-niacinamide-ampoule-serum/for/oily-skin