# Anua Niacinamide 10% + TXA 4% Serum for oily acne-prone skin

**Lovi Fit: Superior fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Anua](https://lovi.care/skincare/ca/brands/anua)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for oily acne-prone skin.

## Why this fit

- Excellent suitability for your oily skin and acne concerns is provided by niacinamide, which helps regulate sebum production and improve skin texture, complemented by tranexamic acid for enhanced skin radiance.
- Glycerin and panthenol further support your skin by offering humectant action and soothing benefits, contributing to overall skin comfort and balance.
- The product is safe for your skin, featuring a gentle formulation with no harsh ingredients and incorporating soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin): Superior (this page)

## Key ingredients

Niacinamide, Txa Tranexamic Acid, Hyaluronic Acid, Panthenol, Allantoin

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Based on a very large amount of data, this serum is highly effective at fading post-acne marks and evening out skin tone, with many users reporting a radiant glow within weeks. While generally well-tolerated and hydrating for many, a significant number of users find the serum leaves a sticky residue, and a smaller portion experience breakouts or irritation, possibly due to the high niacinamide concentration.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Brightens skin (often mentioned)
- Disliked: Sticky finish (often mentioned)
- Liked: Hydrating (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: Caused irritation (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Anua Niacinamide 10% + TXA 4% Serum one of the best fits for oily acne-prone skin?

This serum is one of the best fits because niacinamide helps regulate oil and smooth skin texture while tranexamic acid adds radiance. Glycerin and panthenol further support your skin by keeping it hydrated and calm.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Niacinamide and tranexamic acid make this serum a great fit by helping control oil and brighten your skin. Glycerin and panthenol also support your skin by keeping it hydrated and calm.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### What does Tranexamic Acid do for oily acne-prone skin?

Tranexamic acid helps reduce redness and inflamed spots like pimples and pustules on oily, acne-prone skin. It may also fade lingering dark marks left behind by breakouts with a very low chance of irritation.
Sources: [Journal of Research in Medical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37213446/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35388589/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment serum goes in your evening routine, applied after cleansing and before your moisturizer. Putting it at night keeps things simple and avoids extra sun sensitivity, while ingredients like niacinamide help control oil and improve texture.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this serum with retinol, and in what order?

Yes, you can use this treatment with retinol by applying the treatment first in your evening routine and following with a moisturizer, as the gentle formulation with soothing components is unlikely to cause irritation.

### How often should I use this serum?

This treatment serum is used in your evening routine, applying it once a day or a few times a week depending on how your skin responds. It features a gentle formula with soothing ingredients that help keep oily and acne-prone skin comfortable and balanced.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to cause breakouts for oily acne-prone skin, as it features a gentle formula with soothing ingredients like panthenol and allantoin that help keep skin calm. However, some reviewers do moderately report breakouts, which may happen depending on individual sensitivities.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — CA$24.44 at Amazon
- [Dr.Althea Vitamin C Boosting Serum](https://lovi.care/skincare/ca/p/dr-althea/vitamin-c-boosting-serum/for/oily-acne-prone-skin) — High fit — CA$27.99 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/ca/p/cosrx/the-vitamin-c-23-serum/for/oily-acne-prone-skin) — High fit — CA$33.98 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — CA$20.96 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — CA$37.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/ca/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — CA$29.98 at Amazon

## Where to buy

- Amazon.ca: CA$28.00 (https://www.amazon.ca/dp/B0CLLV2T1P?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Sephora: CA$15.00 (https://www.sephora.com/ca/en/product/niacinamide-10-txa-4-serum-30ml-P521378?skuId=2959088)
Prices checked 10 Oct – 3 Nov 2026.

## Ingredients

Water, Niacinamide, Glycerin, Butylene Glycol, 1,2-Hexanediol, Betaine, Panthenol, Hyaluronic Acid, Allantoin, Tocopherol, Ethylhexylglycerin, Xanthan Gum, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin (this page)
- Australia: https://lovi.care/skincare/au/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin