# Anua Niacinamide 10% + TXA 4% Serum for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Anua](https://lovi.care/skincare/ca/brands/anua)
Category: [Serums and treatments](https://lovi.care/skincare/ca/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for dry sensitive skin.

## Why this fit

- Highly suitable for your dry and sensitive skin, this serum leverages niacinamide to offer moderate brightening and improve skin tone, while glycerin, panthenol, and hyaluronic acid provide essential hydration and barrier support for dry or flaky skin.
- The inclusion of tocopherol offers antioxidant benefits, further complementing the formula's ability to soothe and nourish your skin.
- The product is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin): Superior

## Key ingredients

Niacinamide, Txa Tranexamic Acid, Hyaluronic Acid, Panthenol, Allantoin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Based on a very large amount of data, this serum is highly effective at fading post-acne marks and evening out skin tone, with many users reporting a radiant glow within weeks. While generally well-tolerated and hydrating for many, a significant number of users find the serum leaves a sticky residue, and a smaller portion experience breakouts or irritation, possibly due to the high niacinamide concentration.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Brightens skin (often mentioned)
- Disliked: Sticky finish (often mentioned)
- Liked: Hydrating (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: Caused irritation (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Anua Niacinamide 10% + TXA 4% Serum a great fit for dry sensitive skin?

This serum is a great fit because it uses glycerin, panthenol, and hyaluronic acid to deliver essential moisture and support the skin barrier, while niacinamide helps brighten your skin tone. It also contains tocopherol to soothe and nourish your dry, sensitive skin safely without harsh ingredients.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for dry sensitive skin?

This serum is a great fit because glycerin, panthenol, and hyaluronic acid provide essential hydration and barrier support for dry skin, while niacinamide and tocopherol help soothe and nourish. It is unlikely to cause irritation because harsh ingredients are absent.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### What does Tranexamic Acid do for dry sensitive skin?

Tranexamic acid helps dry sensitive skin by repairing the skin barrier and soothing irritation. It works well to calm redness and restore moisture without causing heavy side effects.
Sources: [International Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/23967870/), [Clinical, Cosmetic and Investigational Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38895607/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in the evening routine after your soothing toner and before your moisturizer. Putting it in the evening keeps things simple and gives extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate and calm your skin, followed by your retinol. This approach helps nourish dry, sensitive skin while minimizing potential irritation from the retinol.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

This serum fits your dry sensitive skin well and is best used in your evening routine for simplicity and safety. It helps brighten your skin tone while glycerin, panthenol, and hyaluronic acid provide essential hydration and barrier support.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is a great fit for your dry sensitive skin because it relies on soothing ingredients like panthenol and allantoin that are unlikely to clog pores. However, some reviewers do report moderate breakouts from this product, so you may want to patch test it first.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [KraveBeauty Great Barrier Relief](https://lovi.care/skincare/ca/p/kravebeauty/great-barrier-relief/for/dry-sensitive-skin) — High fit — CA$40.00 at Amazon
- [The Ordinary Matrixyl 10% + HA](https://lovi.care/skincare/ca/p/the-ordinary/matrixyl-10-ha/for/dry-sensitive-skin) — High fit — CA$14.40 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/ca/p/skin1004/probio-cica-intensive-ampoule/for/dry-sensitive-skin) — High fit — CA$24.44 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — CA$20.19 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/ca/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — CA$49.00 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/ca/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — CA$38.00 at Amazon

## Where to buy

- Amazon.ca: CA$28.00 (https://www.amazon.ca/dp/B0CLLV2T1P?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- Sephora: CA$15.00 (https://www.sephora.com/ca/en/product/niacinamide-10-txa-4-serum-30ml-P521378?skuId=2959088)
Prices checked 10 Oct – 3 Nov 2026.

## Ingredients

Water, Niacinamide, Glycerin, Butylene Glycol, 1,2-Hexanediol, Betaine, Panthenol, Hyaluronic Acid, Allantoin, Tocopherol, Ethylhexylglycerin, Xanthan Gum, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin (this page)
- Australia: https://lovi.care/skincare/au/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/niacinamide-10-txa-4-serum/for/dry-sensitive-skin