# Anua Heartleaf 78% Soothing Cream for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Anua](https://lovi.care/skincare/ca/brands/anua)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Offers moderate benefits for your acne and blemishes due to Houttuynia Cordata Extract and Centella Asiatica Extract, which have soothing and anti-inflammatory properties that are suitable for your combination skin.
- The formulation provides excellent moisturizing and soothing effects, supporting barrier repair and hydration for your skin.
- The safety profile is excellent, with no risks of irritation for your acne-prone skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/oily-skin): Superior
- [Dry skin](https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/oily-acne-prone-skin): High

## Key ingredients

Heartleaf Extract, Centella Asiatica Extract, Allantoin, Jojoba Oil, Hydrolyzed Hyaluronic Acid

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Clay jojoba oil facial masks reduced total skin lesions by a mean of 54% after 6 weeks in 133 participants with acne-prone, lesioned skin and mild acne compared to baseline. ([Forschende Komplementarmedizin, 2012](https://pubmed.ncbi.nlm.nih.gov/22585103/))
- Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream. ([Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27013898/))
- Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31238562/))
- Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37754433/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Topical application of jojoba wax reduced LPS-induced secretion of IL-6, IL-8, and TNFα by approximately 30% and increased the synthesis of pro-collagen III and hyaluronic acid compared to untreated skin in an ex-vivo human skin organ culture model. ([Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/))
- Topical jojoba oil application in male mice decreased exercise-induced pro-inflammatory gene expression (Il-1b and Il-6 in soleus, Il-1b in gastrocnemius) compared to untreated exercised mice. ([Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/41154623/))
- Nanolipidgel formulations with argan or jojoba oil and humectants demonstrate good sensory attributes, instrumental properties, and moisturizing efficacy for cosmetic application. ([International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24772476/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on limited data, users find this cream to be a lightweight, gel-like moisturizer that effectively calms redness and cools the skin, making it suitable for oily, acne-prone, and sensitive skin types. However, individuals with dry or dehydrated skin often report it is not hydrating enough on its own.

- Liked: Soothing & calming (mostly mentioned)
- Liked: Lightweight gel texture (often mentioned)
- Disliked: Insufficient hydration (often mentioned)
- Liked: Cooling effect (sometimes noted)
- Liked: Safe for sensitive/acne skin (sometimes noted)
- Disliked: Cooling discomfort (rarely noted)
- Disliked: Scent/smell (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Anua Heartleaf 78% Soothing Cream a great fit for acne-prone skin?

Anua Heartleaf 78% Soothing Cream is a great fit for acne-prone skin because it offers soothing and anti-inflammatory benefits to help calm breakouts. It also provides excellent moisture and supports skin barrier repair without the risk of irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for acne-prone skin?

This cream is a great fit for acne-prone skin because it contains Heartleaf extract and Centella Asiatica extract, which help soothe the skin and reduce redness. It also features jojoba oil and hyaluronic acid to provide hydration while maintaining a very low risk of irritation.
Sources: [Forschende Komplementarmedizin, 2012](https://pubmed.ncbi.nlm.nih.gov/22585103/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Heartleaf Extract do for acne-prone skin?

Heartleaf Extract helps calm acne-prone skin by reducing redness, swelling, and breakouts. Studies show it helps lower inflammation and target acne-causing bacteria without irritating the skin.
Sources: [Bioscience, Biotechnology, and Biochemistry, 2016](https://pubmed.ncbi.nlm.nih.gov/27023331/), [The Journal of Dermatological Treatment, 2021](https://pubmed.ncbi.nlm.nih.gov/31424962/)

### What does Centella Asiatica Extract do for acne-prone skin?

Centella asiatica extract helps calm angry skin, reduces redness, and supports healing for breakouts. It is unlikely to cause irritation and may improve overall skin clarity when used consistently.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### Where does this cream go in a skincare routine for acne-prone skin?

This cream goes as the moisturizer step in both your morning and evening skincare routines. It helps keep your skin hydrated and calm without causing irritation or breakouts.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this cream with retinol, and in what order?

Yes, you can use this cream with retinol by applying the cream afterward to keep your skin calm and hydrated. Using a barrier-supporting moisturizer alongside active treatments helps reduce irritation and dryness while keeping your skin smooth.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily as part of your morning and evening routine to keep your skin hydrated and calm. Regular daily application helps improve moisture levels and supports skin barrier repair without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to clog pores or cause breakouts for acne-prone skin because it has a very safe formula without harsh ingredients and includes soothing components. It helps calm blemishes and supports skin healing while keeping your face comfortably moisturized.
Sources: [Forschende Komplementarmedizin, 2012](https://pubmed.ncbi.nlm.nih.gov/22585103/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because its gentle ingredients are safe for thinner areas. The skin around the eyes and body may benefit from the soothing and hydrating extracts, which help keep these areas smooth and calm without irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ca/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — CA$24.99 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/ca/p/drunk-elephant/protini-polypeptide-cream/for/acne-prone-skin) — Superior fit — CA$95.99 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/ca/p/belif/the-true-cream-aqua-bomb/for/acne-prone-skin) — High fit — CA$49.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/ca/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — CA$22.95 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — CA$41.00 at Amazon
- SPF: [innisfree Daily UV Defense Mineral Sunscreen](https://lovi.care/skincare/ca/p/innisfree/daily-uv-defense-mineral-sunscreen/for/acne-prone-skin) — Superior fit — CA$24.50 at Amazon

## Where to buy

No store in Canada has a checked price for this product, so the page shows none.

## Ingredients

Houttuynia Cordata Extract, Methylpropanediol, Propylheptyl Caprylate, Butylene Glycol, 1,2-Hexanediol, Polyglyceryl-6 Distearate, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Centella Asiatica Extract, Ficus Carica Fruit Extract, Pumpkin Fruit Extract, Acmella Oleracea Extract, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate Vp Copolymer, Jojoba Esters, Xanthan Gum, Cetyl Alcohol, Polyglyceryl-3 Beeswax, Water, Phytosqualane, Panthenol, Menthyl Pca, Ethyl Menthane Carboxamide, Fructooligosaccharides, Beta-Glucan, Allantoin, Hydrolyzed Hyaluronic Acid, Glycine, Ceramide Np, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Valine, Proline, Isoleucine, Histidine, Cysteine, Methionine, Avena Sativa Kernel Flour Oat Kernel Flour, Silica, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin (this page)
- Australia: https://lovi.care/skincare/au/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/heartleaf-78-soothing-cream/for/acne-prone-skin