# Anua Heartleaf 70% Soothing Cream for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Brand: [Anua](https://lovi.care/skincare/ca/brands/anua)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/ca/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Excellent suitability for your combination skin and acne concerns is provided by Houttuynia Cordata Extract and Centella Asiatica Extract, which offer significant anti-inflammatory and soothing benefits to aid in skin recovery and reduce breakouts.
- Niacinamide further supports seboregulation and enhances the overall efficacy for your skin type, while Panthenol ensures adequate hydration and comfort.
- The formulation is safe for your skin, with no harsh ingredients and a focus on calming components like Centella Asiatica Extract and Panthenol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/oily-acne-prone-skin): High

## Key ingredients

Heartleaf Extract, Centella Asiatica Extract, Portulaca Oleracea Extract, Niacinamide, Panthenol

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream. ([Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27013898/))
- Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31238562/))
- Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37754433/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical purslane at 5% and 10% concentrations achieved alleviation of symptoms and lesion remission comparable to topical 0.1% triamcinolone acetonide in 34 subjects with oral lichen planus over 90 days. ([BMC Oral Health, 2023](https://pubmed.ncbi.nlm.nih.gov/37726676/))
- Facial masks containing low-temperature extracted Portulaca oleracea protect sensitive skin from photothermal stimulation and improve skin barrier function during photorejuvenation. ([Cutaneous and Ocular Toxicology, 2025](https://pubmed.ncbi.nlm.nih.gov/41182319/))
- Portulaca oleracea extract ameliorated skin barrier damage and inflammation induced by combined exposure to glycolic acid and UVB in HaCaT cells. ([Cutaneous and Ocular Toxicology, 2022](https://pubmed.ncbi.nlm.nih.gov/35920724/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo. ([Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/))

## What reviewers say

Based on a very large amount of data, this lightweight gel-cream is highly effective at instantly soothing redness and strengthening the skin barrier, making it ideal for sensitive, acne-prone, and combination skin types. It provides a refreshing burst of hydration and applies smoothly under makeup. Users with very dry skin, however, may find it insufficient for intense moisture needs, particularly during colder months.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Soothes redness (mostly mentioned)
- Liked: Provides hydration (often mentioned)
- Liked: Good ingredients (sometimes noted)
- Liked: Works with makeup (sometimes noted)
- Disliked: Not enough moisture (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Expensive for size (rarely noted)
- Disliked: Texture issues (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes ANUA Heartleaf 70% Soothing Cream a great fit for acne-prone skin?

This cream is a great fit because Heartleaf Extract and Centella Asiatica Extract calm redness and help reduce breakouts. Niacinamide helps balance oil, while Panthenol keeps your skin feeling comfortable and hydrated.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this cream a good fit for acne-prone skin?

This cream is a great fit for acne-prone skin because Heartleaf Extract and Centella Asiatica Extract calm redness and help breakouts heal. Niacinamide helps balance oil, while Panthenol keeps your skin feeling comfortable and hydrated.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Heartleaf Extract do for acne-prone skin?

Heartleaf Extract helps calm acne-prone skin by reducing redness, swelling, and breakouts. Studies show it helps lower inflammation and target acne-causing bacteria without irritating the skin.
Sources: [Bioscience, Biotechnology, and Biochemistry, 2016](https://pubmed.ncbi.nlm.nih.gov/27023331/), [The Journal of Dermatological Treatment, 2021](https://pubmed.ncbi.nlm.nih.gov/31424962/)

### What does Centella Asiatica Extract do for acne-prone skin?

Centella asiatica extract helps calm angry skin, reduces redness, and supports healing for breakouts. It is unlikely to cause irritation and may improve overall skin clarity when used consistently.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### Where does this cream go in a skincare routine for acne-prone skin?

This moisturizing treatment goes near the end of your routine, used as a moisturizer in the morning and evening. It helps calm breakouts and keeps skin comfortable because it contains soothing ingredients like Heartleaf Extract, Centella Asiatica Extract, and Panthenol.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream with retinol, and in what order?

Yes, you can use this cream with retinol by applying the moisturizer after your retinol treatment to help calm the skin and reduce irritation. Using a barrier-supporting moisturizer alongside active treatments is generally safe and helps maintain skin comfort.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatological Treatment, 2016](https://pubmed.ncbi.nlm.nih.gov/26293170/)

### How often should I use this cream?

This cream is a great fit for your acne-prone skin and is gentle enough to use daily as part of your morning and evening routine. Ingredients like heartleaf and centella asiatica help calm breakouts and keep your skin comfortable.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to clog pores or cause breakouts for acne-prone skin because it features calming heartleaf and centella asiatica extracts that help soothe irritation and reduce breakouts. It also contains niacinamide to help balance oil and panthenol to keep skin comfortable without heavy oils.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this cream around the eyes or on my body?

This moisturizing treatment is well suited for the thin skin around the eyes and body because its calming ingredients like Centella Asiatica Extract and Panthenol help soothe and hydrate sensitive areas without harsh components. Clinical studies show that similar soothing creams and panthenol-containing formulas provide good skin tolerance and improve hydration in delicate regions.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ca/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — CA$24.99 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/ca/p/drunk-elephant/protini-polypeptide-cream/for/acne-prone-skin) — Superior fit — CA$95.99 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/ca/p/belif/the-true-cream-aqua-bomb/for/acne-prone-skin) — High fit — CA$49.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/ca/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — CA$22.95 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — CA$41.00 at Amazon
- SPF: [innisfree Daily UV Defense Mineral Sunscreen](https://lovi.care/skincare/ca/p/innisfree/daily-uv-defense-mineral-sunscreen/for/acne-prone-skin) — Superior fit — CA$24.50 at Amazon

## Where to buy

- Amazon.ca: CA$40.53 (https://www.amazon.ca/dp/B0BN38JCXP?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Houttuynia Cordata Extract, Butylene Glycol, Glycerin, Isoamyl Laurate, Water, Pentylene Glycol, 1,2-Hexanediol, Centella Asiatica Extract, Portulaca Oleracea Extract, Betaine, Madecassic Acid, Asiatic Acid, Asiaticoside, Chlorella Vulgaris Extract, Panthenol, Ethylhexylglycerin, Hydrogenated Polydecene, Glucose, Niacinamide, Vinyl Dimethicone, Caprylyl Methicone, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Dimethiconol, Polymethylsilsesquioxane, Glyceryl Acrylate Acrylic Acid Copolymer, Tromethamine, Ammonium Acryloyldimethyltaurate Vp Copolymer, Fructooligosaccharides, Fructose, Dipotassium Glycyrrhizate, Sodium Phytate, Dipropylene Glycol, Tocopherol, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin (this page)
- Australia: https://lovi.care/skincare/au/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin