Acure Ultra Hydrating Overnight Dream Cream for skin with dark spots

How to apply

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Application of 12.5% melatonin cream significantly reduced natural sunlight-induced erythema compared to placebo and no treatment in healthy volunteers, while lower doses (0.5% and 2.5%) showed no difference.

  Journal of Dermatological Science, 2016

• Cosmetic formulations containing lycopene and melatonin showed significant differences in skin sebum content, hydration, elasticity, erythema index, and melanin index compared to control in 36 healthy women.

  Skin Pharmacology and Physiology, 2020

• Topical application of 12.5% melatonin reduced erythema induced by natural sunlight compared to placebo and no treatment in participants with an erythema reaction, without causing significant effects on cognition.

  Danish Medical Journal, 2017

• Unencapsulated cold-pressed industrial hemp seed oil at 0.12 mg/mL accelerated wound healing and increased normal human dermal fibroblast cell proliferation by 72% at 48 hours compared to baseline, though microencapsulation reduced this biological activity.

  Journal of Oleo Science, 2026

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical cream containing saffron extract and avocado oil improved wrinkle grading, reduced nasolabial fold area and volume, and increased skin elasticity in twenty healthy volunteers over 12 weeks without allergic reactions.

  Journal of Cosmetic Dermatology, 2020

• Topical treatment with SSFAO 50% or avocado oil increased wound contraction, reepithelialization, collagen density, and tensile strength while showing anti-inflammatory activity compared to petroleum jelly in rats.

  Evidence-based Complementary and Alternative Medicine, 2013

Why other moisturizers fit skin with dark spots better

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2014

• Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.

  International Journal of Medical Sciences, 2021

Ingredients

Water, Persea Gratissima Oil Avocado Oil, Prunus Armeniaca Kernel Oil Apricot Kernel Oil, Glyceryl Stearate Citrate, Glycerin, Cetyl Alcohol, Glyceryl Stearate, Prunus Amygdalus Dulcis Oil, Jojoba Seed Extract, Glyceryl Laurate, Phenethyl Alcohol, Citrus Aurantium Dulcis Peel Oil, Camphor Oil, Lemon Peel Oil, Citrus Nobilis Peel Oil Mandarin Orange Peel Oil, Myroxylon Pereirae Oil Balsam Peru Oil, Citrus Aurantium Dulcis Fruit Extract, Elettaria Cardamomum Oil, Piper Nigrum Oil Fruit, Canarium Luzonicum Nonvolatiles Gum, Dipteryx Odorata Seed Oil, Vetiveryl Acetate, Bulnesia Sarmientoi Oil Wood, Clove Oil Bud, Peppermint Oil, Juniperus Virginiana Oil, Lavandula Hybrida Oil, Jasmine Oil, Glyceryl Undecylenate, Xanthan Gum, Ethylhexylglycerin, Cannabis Sativa Seed Oil, Citric Acid, Melatonin, Sodium Phytate, Aspalathus Linearis Leaf Extract, Calendula Officinalis Flower Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Euterpe Oleracea Fruit Extract, Punica Granatum Extract, Rosa Canina Fruit Extract, Blackberry Fruit Extract, Lauric Acid, Sodium Hyaluronate, Lentinus Edodes Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.