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Protease and palmitoyl tripeptide-1

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

Protease and palmitoyl tripeptide-1: keep them apart

Keep them apart

Use them at different times of day, applying the protease first and the peptide later, because they cancel each other out. The protease enzyme breaks down the peptide before it can smooth your skin. You can separate them by using one in the morning and the other at night.

Protease products

Palmitoyl tripeptide-1 products

Questions and answers

Can you use protease and palmitoyl tripeptide-1 together?

Keep protease and palmitoyl tripeptide-1 apart because enzymes degrade peptides and render them inactive.

Which goes first, protease or palmitoyl tripeptide-1?

Keep protease and palmitoyl tripeptide-1 apart by using them in separate routines because proteolytic enzymes may degrade cosmetic peptides and render them inactive.

Are protease and palmitoyl tripeptide-1 good for sensitive skin?

Keep protease and palmitoyl tripeptide-1 apart in your routine because the enzyme degrades the peptide bonds and renders the active inactive.

Research on protease and palmitoyl tripeptide-1

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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