# Niacinamide and lactobionic acid Page: https://lovi.care/skincare/ca/ingredients/niacinamide-and-lactobionic-acid The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada. Depends on the strength Use them together in the same routine, applying the mild acid first and [niacinamide](https://lovi.care/skincare/ca/ingredients/niacinamide) second to smooth skin texture without irritation. Niacinamide supports your skin barrier while the mild acid gently smooths your skin. You can continue using this pairing since it helps improve cell renewal. - [All about niacinamide](https://lovi.care/skincare/ca/ingredients/niacinamide) - [All about lactobionic acid](https://lovi.care/skincare/ca/ingredients/lactobionic-acid) ### [Niacinamide](https://lovi.care/skincare/ca/ingredients/niacinamide) products - [La Roche-Posay Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit — [CA$31.00 at Amazon](https://www.amazon.ca/dp/B07942ZQBT?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [CA$20.96 at Amazon](https://www.amazon.ca/dp/B08B8X96Q6?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Cetaphil Gentle Skin Cleanser](https://lovi.care/skincare/ca/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [CA$17.97 at Amazon](https://www.amazon.ca/dp/B00BMJTOSW?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [CA$30.56 at Amazon](https://www.amazon.ca/dp/B0052EM8L8?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Dr. Althea 345 Relief Cream](https://lovi.care/skincare/ca/p/dr-althea/345-relief-cream/for/acne-prone-skin) — Superior fit — [CA$28.45 at Amazon](https://www.amazon.ca/dp/B07PK2P2XB?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Biodance Bio-Collagen Real Deep Mask](https://lovi.care/skincare/ca/p/biodance/bio-collagen-real-deep-mask/for/mature-skin) — Superior fit — [CA$24.09 at Amazon](https://www.amazon.ca/dp/B0B2RM68G2?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/ca/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [CA$35.96 at Amazon](https://www.amazon.ca/dp/B0012J30LY?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [CeraVe Resurfacing Retinol Serum](https://lovi.care/skincare/ca/p/cerave/resurfacing-retinol-serum/for/dark-spots) — High fit — [CA$25.98 at Amazon](https://www.amazon.ca/dp/B09NM9TFF2?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [CA$20.96 at Amazon](https://www.amazon.ca/dp/B083GG19DS?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Medicube PDRN Pink Peptide Serum](https://lovi.care/skincare/ca/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [CA$22.00 at Amazon](https://www.amazon.ca/dp/B0DBF65JYY?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [CeraVe Renewing SA Cleanser](https://lovi.care/skincare/ca/p/cerave/renewing-sa-cleanser/for/oily-acne-prone-skin) — High fit — [CA$20.96 at Amazon](https://www.amazon.ca/dp/B08PR8YSBT?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Medicube Collagen Jelly Cream](https://lovi.care/skincare/ca/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [CA$33.18 at Amazon](https://www.amazon.ca/dp/B0CM2PPNMW?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) ### [Lactobionic acid](https://lovi.care/skincare/ca/ingredients/lactobionic-acid) products - [Verb Ghost Exfoliating Scalp Nectar](https://lovi.care/skincare/ca/p/verb/ghost-exfoliating-scalp-nectar/for/oily-skin) — Superior fit - [Elemis Pro-Collagen Marine Moisture Essence](https://lovi.care/skincare/ca/p/elemis/pro-collagen-marine-moisture-essence/for/mature-skin) — Average fit - [Elemis Pro-Collagen Tri-Acid Peel](https://lovi.care/skincare/ca/p/elemis/pro-collagen-tri-acid-peel/for/dark-spots) — High fit - [Skintific AHA BHA PHA LHA Peeling Solution](https://lovi.care/skincare/ca/p/skintific/aha-bha-pha-lha-peeling-solution/for/oily-acne-prone-skin) — High fit - [Benton PHA Peeling Toner](https://lovi.care/skincare/ca/p/benton/pha-peeling-toner/for/dark-spots) — Superior fit - [VT COSMETICS Cica Skin](https://lovi.care/skincare/ca/p/vt-cosmetics/cica-skin/for/sensitive-skin) — Superior fit — [CA$29.17 at Amazon](https://www.amazon.ca/dp/B0C2TQ24VY?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Estée Lauder Perfectly Clean Multi-Action Toning Lotion/Refiner](https://lovi.care/skincare/ca/p/estee-lauder/perfectly-clean-multi-action-toning-lotion-refiner/for/oily-skin) — High fit — [CA$48.00 at Amazon](https://www.amazon.ca/dp/B00CAUJJM8?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [COSRX Full Fit Propolis Synergy Pad](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-pad/for/mature-skin) — High fit - [MZ Skin Cleanse & Clarify Dual Action AHA Cleanser & Mask](https://lovi.care/skincare/ca/p/mz-skin/cleanse-and-clarify-dual-action-aha-cleanser-and-mask/for/acne-prone-skin) — High fit — [CA$119.95 at Amazon](https://www.amazon.ca/dp/B07D5J95NG?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [MZ Skin Radiance & Renewal Instant Clarity Refining Mask](https://lovi.care/skincare/ca/p/mz-skin/radiance-and-renewal-instant-clarity-refining-mask/for/oily-acne-prone-skin) — High fit ## Questions and answers ### Can you use niacinamide and lactobionic acid together? Yes, you can use [niacinamide](https://lovi.care/skincare/ca/ingredients/niacinamide) and [lactobionic acid](https://lovi.care/skincare/ca/ingredients/lactobionic-acid) together depending on the strength, as this combination helps improve cell renewal without irritation. ### Which goes first, niacinamide or lactobionic acid? Yes, they can be combined depending on the strength, with niacinamide and lactobionic acid helping to improve cell renewal and smooth texture without irritation. ### Are niacinamide and lactobionic acid good for sensitive skin? Yes, niacinamide and lactobionic acid are beneficial together because niacinamide supports the barrier while mild acids smooth texture to improve cell renewal without irritation. This combination helps normalize and smooth dull or uneven skin. ## Research on niacinamide and lactobionic acid - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021 - [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021 - [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024 - [Effects of lactobionic acid peel, aluminum oxide crystal microdermabrasion, and both procedures on skin hydration, elasticity, and transepidermal water loss](https://pubmed.ncbi.nlm.nih.gov/30661294/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019 - [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Lactobionic acid · Journal of Cosmetic Dermatology, 2010 - [A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study](https://pubmed.ncbi.nlm.nih.gov/30859734/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019 ## Other combinations - Depends on the strength: [Retinol and niacinamide](https://lovi.care/skincare/ca/ingredients/retinol-and-niacinamide) - Depends on the strength: [AHA blend glycolic and citric acids and niacinamide](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-niacinamide) - Depends on the strength: [Niacinamide and citric acid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-citric-acid) - Depends on the strength: [Glycolic acid and niacinamide](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-niacinamide) - Depends on the strength: [Niacinamide and lactic acid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-lactic-acid) - Depends on the strength: [Niacinamide and mandelic acid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-mandelic-acid) - Depends on the strength: [Niacinamide and salicylic acid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-salicylic-acid) - Depends on the strength: [Niacinamide and gluconolactone](https://lovi.care/skincare/ca/ingredients/niacinamide-and-gluconolactone) - Work well together: [Niacinamide and cholesterol](https://lovi.care/skincare/ca/ingredients/niacinamide-and-cholesterol) - Work well together: [Niacinamide and lauric acid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-lauric-acid) - Work well together: [Niacinamide and linoleic acid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-linoleic-acid) - Work well together: [Niacinamide and tri-ceramide complex](https://lovi.care/skincare/ca/ingredients/niacinamide-and-tri-ceramide-complex) - Depends on the strength: [Adapalene and niacinamide](https://lovi.care/skincare/ca/ingredients/adapalene-and-niacinamide) - Depends on the strength: [Niacinamide and granactive retinoid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-granactive-retinoid) - Depends on the strength: [Niacinamide and hydroxypinacolone retinoate](https://lovi.care/skincare/ca/ingredients/niacinamide-and-hydroxypinacolone-retinoate) - Depends on the strength: [Niacinamide and pro-retinol](https://lovi.care/skincare/ca/ingredients/niacinamide-and-pro-retinol) - Depends on the strength: [Niacinamide and retinal](https://lovi.care/skincare/ca/ingredients/niacinamide-and-retinal) - Depends on the strength: [Niacinamide and retinoid blend](https://lovi.care/skincare/ca/ingredients/niacinamide-and-retinoid-blend) - Depends on the strength: [Niacinamide and tretinoin](https://lovi.care/skincare/ca/ingredients/niacinamide-and-tretinoin) - Depends on the strength: [Niacinamide and vitamin A](https://lovi.care/skincare/ca/ingredients/niacinamide-and-vitamin-a) - Work well together: [Hyaluronic acid and lactobionic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-lactobionic-acid) - Depends on the strength: [Niacinamide and acetyl hexapeptide-3](https://lovi.care/skincare/ca/ingredients/niacinamide-and-acetyl-hexapeptide-3) - Depends on the strength: [Niacinamide and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/niacinamide-and-bio-placenta-peptides) - Depends on the strength: [Niacinamide and collagen peptide](https://lovi.care/skincare/ca/ingredients/niacinamide-and-collagen-peptide) - Depends on the strength: [Niacinamide and copper peptide](https://lovi.care/skincare/ca/ingredients/niacinamide-and-copper-peptide) - Depends on the strength: [Niacinamide and hexapeptide](https://lovi.care/skincare/ca/ingredients/niacinamide-and-hexapeptide) - Depends on the strength: [Niacinamide and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/niacinamide-and-hexapeptide-9) - Depends on the strength: [Niacinamide and palmitoyl pentapeptide-4](https://lovi.care/skincare/ca/ingredients/niacinamide-and-palmitoyl-pentapeptide-4) - Depends on the strength: [Niacinamide and palmitoyl tripeptide-1](https://lovi.care/skincare/ca/ingredients/niacinamide-and-palmitoyl-tripeptide-1) - Depends on the strength: [Niacinamide and peptide-rich plasma](https://lovi.care/skincare/ca/ingredients/niacinamide-and-peptide-rich-plasma) - Depends on the strength: [Niacinamide and triple peptide blend](https://lovi.care/skincare/ca/ingredients/niacinamide-and-triple-peptide-blend) - Work well together: [Niacinamide and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-hyaluronic-acid) - Work well together: [AHA blend glycolic and citric acids and lactobionic acid](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-lactobionic-acid) - Work well together: [Lactobionic acid and citric acid](https://lovi.care/skincare/ca/ingredients/lactobionic-acid-and-citric-acid) - Work well together: [Glycolic acid and lactobionic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-lactobionic-acid) - Work well together: [Lactic acid and lactobionic acid](https://lovi.care/skincare/ca/ingredients/lactic-acid-and-lactobionic-acid) - Work well together: [Mandelic acid and lactobionic acid](https://lovi.care/skincare/ca/ingredients/mandelic-acid-and-lactobionic-acid) - Work well together: [Vitamin C and lactobionic acid](https://lovi.care/skincare/ca/ingredients/vitamin-c-and-lactobionic-acid) - Work well together: [Niacinamide and bakuchiol](https://lovi.care/skincare/ca/ingredients/niacinamide-and-bakuchiol) - Work well together: [Niacinamide and zinc](https://lovi.care/skincare/ca/ingredients/niacinamide-and-zinc) - Work well together: [Niacinamide and zinc gluconate](https://lovi.care/skincare/ca/ingredients/niacinamide-and-zinc-gluconate) - Work well together: [Niacinamide and zinc oxide](https://lovi.care/skincare/ca/ingredients/niacinamide-and-zinc-oxide) - Work well together: [Niacinamide and zinc sulfate](https://lovi.care/skincare/ca/ingredients/niacinamide-and-zinc-sulfate) - Work well together: [Benzoyl peroxide and niacinamide](https://lovi.care/skincare/ca/ingredients/benzoyl-peroxide-and-niacinamide) - Work well together: [Salicylic acid and lactobionic acid](https://lovi.care/skincare/ca/ingredients/salicylic-acid-and-lactobionic-acid) - Keep them apart: [Niacinamide and lipohydroxy acid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-lipohydroxy-acid) - Work well together: [Ferulic acid and niacinamide](https://lovi.care/skincare/ca/ingredients/ferulic-acid-and-niacinamide) - Work well together: [Green tea and niacinamide](https://lovi.care/skincare/ca/ingredients/green-tea-and-niacinamide) - Work well together: [Niacinamide and vitamin E](https://lovi.care/skincare/ca/ingredients/niacinamide-and-vitamin-e) - Keep them apart: [Niacinamide and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/niacinamide-and-isopropyl-alcohol) - Work well together: [Niacinamide and ascorbyl glucoside](https://lovi.care/skincare/ca/ingredients/niacinamide-and-ascorbyl-glucoside) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/niacinamide-and-lactobionic-acid - United Kingdom: https://lovi.care/skincare/uk/ingredients/niacinamide-and-lactobionic-acid - Ireland: https://lovi.care/skincare/ie/ingredients/niacinamide-and-lactobionic-acid - Germany: https://lovi.care/skincare/de/ingredients/niacinamide-and-lactobionic-acid - France: https://lovi.care/skincare/fr/ingredients/niacinamide-and-lactobionic-acid - Italy: https://lovi.care/skincare/it/ingredients/niacinamide-and-lactobionic-acid - Netherlands: https://lovi.care/skincare/nl/ingredients/niacinamide-and-lactobionic-acid - Spain: https://lovi.care/skincare/es/ingredients/niacinamide-and-lactobionic-acid - Canada: https://lovi.care/skincare/ca/ingredients/niacinamide-and-lactobionic-acid (this page) - Australia: https://lovi.care/skincare/au/ingredients/niacinamide-and-lactobionic-acid - Singapore: https://lovi.care/skincare/sg/ingredients/niacinamide-and-lactobionic-acid - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/niacinamide-and-lactobionic-acid - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/niacinamide-and-lactobionic-acid