# Liposome and hexapeptide-9 Page: https://lovi.care/skincare/ca/ingredients/liposome-and-hexapeptide-9 The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada. Work well together Use them together, applying the [liposome](https://lovi.care/skincare/ca/ingredients/liposome) product first and the [hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hexapeptide-9) second, to help the peptide absorb better. The liposome wrapper protects the hexapeptide-9 from breaking down so it works more effectively on your skin. You can continue using them together, but if your skin feels sensitive, you can apply them on alternate nights. - [All about liposome](https://lovi.care/skincare/ca/ingredients/liposome) - [All about hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hexapeptide-9) ### [Liposome](https://lovi.care/skincare/ca/ingredients/liposome) products - [MISSHA Vita C Plus Spot Correcting & Firming Ampoule](https://lovi.care/skincare/ca/p/missha/vita-c-plus-spot-correcting-and-firming-ampoule/for/dry-sensitive-skin) — Superior fit ### [Hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hexapeptide-9) products - [Elemis Pro-Collagen Night Cream](https://lovi.care/skincare/ca/p/elemis/pro-collagen-night-cream/for/dry-sensitive-skin) — Superior fit — [CA$131.00 at Sephora](https://www.sephora.com/ca/en/product/elemis-pro-collagen-anti-aging-night-cream-P514133?skuId=2828507) - [Murad Cellular Hydration Repair Serum](https://lovi.care/skincare/ca/p/murad/cellular-hydration-repair-serum/for/acne-prone-skin) — High fit - [MARY & MAY 6 Peptide Complex Serum](https://lovi.care/skincare/ca/p/mary-and-may/6-peptide-complex-serum/for/mature-skin) — High fit — [CA$28.99 at Amazon](https://www.amazon.ca/dp/B095YHYF33?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) ## Questions and answers ### Can you use liposome and hexapeptide-9 together? Yes, you can use [liposomes](https://lovi.care/skincare/ca/ingredients/liposome) and [hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hexapeptide-9) together because this pairing greatly improves peptide stability and skin penetration while protecting them from degradation. Lovi rates this combination as Superior for all skin types, especially mature and sensitive skin. ### Which goes first, liposome or hexapeptide-9? Liposome and hexapeptide-9 work well together because liposomes help protect peptides from degradation and improve their penetration. You can use this combination daily for all skin types, especially mature and sensitive skin. [Colloids and Surfaces. B, Biointerfaces, 2020](https://pubmed.ncbi.nlm.nih.gov/32535351/) [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40586182/) ### Are liposome and hexapeptide-9 good for sensitive skin? Yes, liposome and hexapeptide-9 work well together for all skin types, especially mature and sensitive skin. Lovi rates the fit for this combination as High. [Colloids and Surfaces. B, Biointerfaces, 2020](https://pubmed.ncbi.nlm.nih.gov/32535351/) [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40586182/) ## Research on liposome and hexapeptide-9 - [Ammonium glycyrrhizate skin delivery from ultradeformable liposomes: A novel use as an anti-inflammatory agent in topical drug delivery](https://pubmed.ncbi.nlm.nih.gov/32535351/) Liposome · Colloids and Surfaces. B, Biointerfaces, 2020 - [Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/40586182/) Hexapeptide-9 · Journal of Cosmetic Dermatology, 2025 ## Other combinations - Keep them apart: [Adapalene and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/adapalene-and-hexapeptide-9) - Keep them apart: [Granactive retinoid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/granactive-retinoid-and-hexapeptide-9) - Keep them apart: [Hydroxypinacolone retinoate and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hydroxypinacolone-retinoate-and-hexapeptide-9) - Keep them apart: [Pro-retinol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/pro-retinol-and-hexapeptide-9) - Keep them apart: [Retinal and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/retinal-and-hexapeptide-9) - Keep them apart: [Retinoid blend and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/retinoid-blend-and-hexapeptide-9) - Depends on the strength: [Retinol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/retinol-and-hexapeptide-9) - Keep them apart: [Tretinoin and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/tretinoin-and-hexapeptide-9) - Keep them apart: [Vitamin A and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/vitamin-a-and-hexapeptide-9) - Work well together: [Liposome and acetyl hexapeptide-3](https://lovi.care/skincare/ca/ingredients/liposome-and-acetyl-hexapeptide-3) - Work well together: [Bio-placenta peptides and liposome](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-liposome) - Work well together: [Liposome and collagen peptide](https://lovi.care/skincare/ca/ingredients/liposome-and-collagen-peptide) - Work well together: [Liposome and copper peptide](https://lovi.care/skincare/ca/ingredients/liposome-and-copper-peptide) - Work well together: [Hexapeptide and liposome](https://lovi.care/skincare/ca/ingredients/hexapeptide-and-liposome) - Work well together: [Microcapsule and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/microcapsule-and-hexapeptide-9) - Work well together: [Liposome and palmitoyl pentapeptide-4](https://lovi.care/skincare/ca/ingredients/liposome-and-palmitoyl-pentapeptide-4) - Work well together: [Liposome and palmitoyl tripeptide-1](https://lovi.care/skincare/ca/ingredients/liposome-and-palmitoyl-tripeptide-1) - Work well together: [Liposome and peptide-rich plasma](https://lovi.care/skincare/ca/ingredients/liposome-and-peptide-rich-plasma) - Work well together: [Liposome and triple peptide blend](https://lovi.care/skincare/ca/ingredients/liposome-and-triple-peptide-blend) - Depends on the strength: [Vitamin C and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/vitamin-c-and-hexapeptide-9) - Work well together: [Betaine and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/betaine-and-hexapeptide-9) - Work well together: [Glycerin and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/glycerin-and-hexapeptide-9) - Work well together: [Hyaluronic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-hexapeptide-9) - Work well together: [Liposome and tri-ceramide complex](https://lovi.care/skincare/ca/ingredients/liposome-and-tri-ceramide-complex) - Depends on the strength: [Niacinamide and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/niacinamide-and-hexapeptide-9) - Work well together: [Panthenol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/panthenol-and-hexapeptide-9) - Work well together: [Bakuchiol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/bakuchiol-and-hexapeptide-9) - Work well together: [Arginine and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/arginine-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and GABA](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-gaba) - Work well together: [Silk amino acids and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/silk-amino-acids-and-hexapeptide-9) - Work well together: [Taurine and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/taurine-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and theanine](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-theanine) - Keep them apart: [AHA blend glycolic and citric acids and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide-9) - Keep them apart: [Citric acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/citric-acid-and-hexapeptide-9) - Keep them apart: [Glycolic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-hexapeptide-9) - Keep them apart: [Lactic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/lactic-acid-and-hexapeptide-9) - Keep them apart: [Mandelic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/mandelic-acid-and-hexapeptide-9) - Work well together: [Coenzyme Q10 and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/coenzyme-q10-and-hexapeptide-9) - Work well together: [Green tea and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/green-tea-and-hexapeptide-9) - Work well together: [Vitamin E and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/vitamin-e-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and beta-sitosterol](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-beta-sitosterol) - Work well together: [Ceramide-building complex and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-hexapeptide-9) - Work well together: [Cholesterol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/cholesterol-and-hexapeptide-9) - Work well together: [Phytosphingosine and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/phytosphingosine-and-hexapeptide-9) - Work well together: [Phytosterol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/phytosterol-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and squalene](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-squalene) - Work well together: [Hexapeptide-9 and tri-ceramide complex](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-tri-ceramide-complex) - Keep them apart: [Salicylic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/salicylic-acid-and-hexapeptide-9) - Keep them apart: [Hexapeptide-9 and baking soda](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-baking-soda) - Keep them apart: [Bleach and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/bleach-and-hexapeptide-9) - Keep them apart: [Potassium hydroxide and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/potassium-hydroxide-and-hexapeptide-9) - Keep them apart: [Hexapeptide-9 and behenyl alcohol](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-behenyl-alcohol) - Keep them apart: [Hexapeptide-9 and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-isopropyl-alcohol) - Keep them apart: [Polyvinyl alcohol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/polyvinyl-alcohol-and-hexapeptide-9) - Keep them apart: [Copper and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/copper-and-hexapeptide-9) - Keep them apart: [Benzoyl peroxide and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/benzoyl-peroxide-and-hexapeptide-9) - Keep them apart: [Magnesium and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/magnesium-and-hexapeptide-9) - Keep them apart: [Zinc and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/zinc-and-hexapeptide-9) - Keep them apart: [Zinc sulfate and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/zinc-sulfate-and-hexapeptide-9) - Keep them apart: [Azelaic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/azelaic-acid-and-hexapeptide-9) - Keep them apart: [Hexapeptide-9 and protease](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-protease) - Keep them apart: [Superoxide dismutase and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/superoxide-dismutase-and-hexapeptide-9) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/liposome-and-hexapeptide-9 - United Kingdom: https://lovi.care/skincare/uk/ingredients/liposome-and-hexapeptide-9 - Ireland: https://lovi.care/skincare/ie/ingredients/liposome-and-hexapeptide-9 - Germany: https://lovi.care/skincare/de/ingredients/liposome-and-hexapeptide-9 - France: https://lovi.care/skincare/fr/ingredients/liposome-and-hexapeptide-9 - Italy: https://lovi.care/skincare/it/ingredients/liposome-and-hexapeptide-9 - Netherlands: https://lovi.care/skincare/nl/ingredients/liposome-and-hexapeptide-9 - Spain: https://lovi.care/skincare/es/ingredients/liposome-and-hexapeptide-9 - Canada: https://lovi.care/skincare/ca/ingredients/liposome-and-hexapeptide-9 (this page) - Australia: https://lovi.care/skincare/au/ingredients/liposome-and-hexapeptide-9 - Singapore: https://lovi.care/skincare/sg/ingredients/liposome-and-hexapeptide-9 - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/liposome-and-hexapeptide-9 - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/liposome-and-hexapeptide-9