# Hyaluronic acid and isopropyl alcohol Page: https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-isopropyl-alcohol The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada. Keep them apart Apply [hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid) first and [isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/isopropyl-alcohol) at different times of day because alcohol dries out skin and ruins the hydration. Alcohol strips away moisture and fights the plumping effects of hyaluronic acid, leaving skin dry and irritated. The shopper can switch to an alcohol-free product or space them out by several hours. - [All about hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid) - [All about isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/isopropyl-alcohol) ### [Hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid) products - [CeraVe Moisturising Cream](https://lovi.care/skincare/ca/p/cerave/moisturising-cream/for/dry-sensitive-skin) — Superior fit — [CA$27.97 at Amazon](https://www.amazon.ca/dp/B083GGFTPW?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [CA$20.19 at Amazon](https://www.amazon.ca/dp/B0843XGN3H?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Rhode Glazing Milk](https://lovi.care/skincare/ca/p/rhode/glazing-milk/for/dry-skin) — Superior fit — [CA$30.00 at Sephora](https://www.sephora.com/ca/en/product/glazing-milk-P519160?skuId=2898419) - [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/ca/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [CA$20.96 at Amazon](https://www.amazon.ca/dp/B08B8X96Q6?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Vanicream Daily Facial Moisturizer](https://lovi.care/skincare/ca/p/vanicream/daily-facial-moisturizer/for/dry-skin) — Superior fit — [CA$21.99 at Shoppers Drug Mart](https://www.shoppersdrugmart.ca/vanicream-daily-facial-moisturizer/p/BB_345334323518?variantCode=345334323518) - [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/ca/p/cosrx/advanced-snail-96-mucin-power-essence/for/dry-skin) — Superior fit — [CA$24.99 at Amazon](https://www.amazon.ca/dp/B07N3SMBRM?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Dr. Althea 345 Relief Cream](https://lovi.care/skincare/ca/p/dr-althea/345-relief-cream/for/acne-prone-skin) — Superior fit — [CA$28.45 at Amazon](https://www.amazon.ca/dp/B07PK2P2XB?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Biodance Bio-Collagen Real Deep Mask](https://lovi.care/skincare/ca/p/biodance/bio-collagen-real-deep-mask/for/mature-skin) — Superior fit — [CA$24.09 at Amazon](https://www.amazon.ca/dp/B0B2RM68G2?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Neutrogena Hydro Boost Water Gel](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [CA$18.98 at Amazon](https://www.amazon.ca/dp/B0CNBG4G4F?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/ca/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [CA$35.96 at Amazon](https://www.amazon.ca/dp/B0012J30LY?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [CeraVe Daily Moisturizing Lotion](https://lovi.care/skincare/ca/p/cerave/daily-moisturizing-lotion/for/dry-skin) — Superior fit — [CA$25.29 at Amazon](https://www.amazon.ca/dp/B0843XPGNN?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [CeraVe Healing Ointment](https://lovi.care/skincare/ca/p/cerave/healing-ointment/for/dry-skin) — High fit — [CA$35.79 at Shoppers Drug Mart](https://www.shoppersdrugmart.ca/cerave-healing-ointment-moisturizing-petrolatum-skin-prot/p/BB_3606000612327?variantCode=3606000612327) ### [Isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/isopropyl-alcohol) products - [Mario Badescu Drying Lotion](https://lovi.care/skincare/ca/p/mario-badescu/drying-lotion/for/oily-skin) — High fit — [CA$34.95 at Amazon](https://www.amazon.ca/dp/B0035AN2WU?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Avène Cleanance Comedomed Anti-Blemish Concentrate](https://lovi.care/skincare/ca/p/avene/cleanance-comedomed-anti-blemish-concentrate/for/acne-prone-skin) — Average fit — [CA$31.20 at Amazon](https://www.amazon.ca/dp/B08FY8Q55Y?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Menarini A-Ret Gel](https://lovi.care/skincare/ca/p/menarini/a-ret-gel/for/oily-skin) — High fit ## Questions and answers ### Can you use hyaluronic acid and isopropyl alcohol together? No, you should keep [hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid) and [isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/isopropyl-alcohol) apart in your routine because alcohol dehydrates the skin and reduces the effectiveness of hyaluronic acid. ### Which goes first, hyaluronic acid or isopropyl alcohol? Keep hyaluronic acid and isopropyl alcohol apart because high amounts of alcohol dehydrate the skin and reduce the effectiveness of hyaluronic acid. ### Are hyaluronic acid and isopropyl alcohol good for sensitive skin? Keep hyaluronic acid and isopropyl alcohol apart because alcohol dehydrates the skin and reduces the effectiveness of hyaluronic acid. Lovi rates this combination as a poor fit for sensitive skin. ## Research on hyaluronic acid and isopropyl alcohol - [Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects](https://pubmed.ncbi.nlm.nih.gov/30287361/) Hyaluronic acid · International Journal of Biological Macromolecules, 2018 - [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Hyaluronic acid · Journal of Pharmacy & Pharmaceutical Sciences, 2015 - [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017 - [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022 - [Liposome, gel and lipogelosome formulations containing sodium hyaluronate](https://pubmed.ncbi.nlm.nih.gov/24724824/) Hyaluronic acid · Journal of Liposome Research, 2014 - [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hyaluronic acid · Dermatologic Therapy, 2022 - [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hyaluronic acid · Aesthetic Plastic Surgery, 2026 - [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022 ## Other combinations - Keep them apart: [Retinol and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/retinol-and-isopropyl-alcohol) - Work well together: [Acetyl hexapeptide-3 and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid) - Work well together: [Bio-placenta peptides and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and collagen peptide](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-collagen-peptide) - Work well together: [Hyaluronic acid and copper peptide](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-copper-peptide) - Work well together: [Hexapeptide and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hexapeptide-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-hexapeptide-9) - Work well together: [Hyaluronic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-palmitoyl-pentapeptide-4) - Work well together: [Hyaluronic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-palmitoyl-tripeptide-1) - Work well together: [Hyaluronic acid and peptide-rich plasma](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-peptide-rich-plasma) - Work well together: [Hyaluronic acid and triple peptide blend](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-triple-peptide-blend) - Work well together: [Gluconolactone and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/gluconolactone-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and lactobionic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-lactobionic-acid) - Work well together: [Hyaluronic acid and ascorbyl glucoside](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-ascorbyl-glucoside) - Work well together: [Coenzyme Q10 and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/coenzyme-q10-and-hyaluronic-acid) - Work well together: [Vitamin E and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/vitamin-e-and-hyaluronic-acid) - Depends on the strength: [AHA blend glycolic and citric acids and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-hyaluronic-acid) - Depends on the strength: [Hyaluronic acid and citric acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-citric-acid) - Depends on the strength: [Glycolic acid and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-hyaluronic-acid) - Depends on the strength: [Lactic acid and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/lactic-acid-and-hyaluronic-acid) - Depends on the strength: [Mandelic acid and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/mandelic-acid-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and tri-ceramide complex](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-tri-ceramide-complex) - Keep them apart: [Azelaic acid and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/azelaic-acid-and-hyaluronic-acid) - Keep them apart: [Salicylic acid and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/salicylic-acid-and-hyaluronic-acid) - Work well together: [Niacinamide and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-hyaluronic-acid) - Keep them apart: [Hyaluronic acid and bergamot oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-bergamot-oil) - Keep them apart: [Hyaluronic acid and camphor oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-camphor-oil) - Keep them apart: [Hyaluronic acid and chamomile oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-chamomile-oil) - Keep them apart: [Hyaluronic acid and clove leaf oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-clove-leaf-oil) - Keep them apart: [Hyaluronic acid and eucalyptus oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-eucalyptus-oil) - Keep them apart: [Hyaluronic acid and geranium oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-geranium-oil) - Keep them apart: [Hyaluronic acid and grapefruit peel oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-grapefruit-peel-oil) - Keep them apart: [Lavender oil and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/lavender-oil-and-hyaluronic-acid) - Keep them apart: [Hyaluronic acid and lemon oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-lemon-oil) - Keep them apart: [Hyaluronic acid and orange oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-orange-oil) - Keep them apart: [Hyaluronic acid and palmarosa oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-palmarosa-oil) - Keep them apart: [Hyaluronic acid and peppermint oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-peppermint-oil) - Keep them apart: [Hyaluronic acid and rose oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-rose-oil) - Keep them apart: [Hyaluronic acid and rosewood oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-rosewood-oil) - Keep them apart: [Hyaluronic acid and sandalwood oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-sandalwood-oil) - Keep them apart: [Tea tree oil and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/tea-tree-oil-and-hyaluronic-acid) - Keep them apart: [Hyaluronic acid and thyme oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-thyme-oil) - Keep them apart: [Hyaluronic acid and wild mint oil](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-wild-mint-oil) - Work well together: [Hyaluronic acid and cholesterol](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-cholesterol) - Work well together: [Hyaluronic acid and lauric acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-lauric-acid) - Work well together: [Linoleic acid and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/linoleic-acid-and-hyaluronic-acid) - Keep them apart: [Acetyl hexapeptide-3 and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/acetyl-hexapeptide-3-and-isopropyl-alcohol) - Keep them apart: [Bio-placenta peptides and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-isopropyl-alcohol) - Keep them apart: [Collagen peptide and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/collagen-peptide-and-isopropyl-alcohol) - Keep them apart: [Copper peptide and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/copper-peptide-and-isopropyl-alcohol) - Keep them apart: [Hexapeptide and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/hexapeptide-and-isopropyl-alcohol) - Keep them apart: [Hexapeptide-9 and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-isopropyl-alcohol) - Keep them apart: [Isopropyl alcohol and palmitoyl pentapeptide-4](https://lovi.care/skincare/ca/ingredients/isopropyl-alcohol-and-palmitoyl-pentapeptide-4) - Keep them apart: [Isopropyl alcohol and palmitoyl tripeptide-1](https://lovi.care/skincare/ca/ingredients/isopropyl-alcohol-and-palmitoyl-tripeptide-1) - Keep them apart: [Isopropyl alcohol and peptide-rich plasma](https://lovi.care/skincare/ca/ingredients/isopropyl-alcohol-and-peptide-rich-plasma) - Keep them apart: [Isopropyl alcohol and triple peptide blend](https://lovi.care/skincare/ca/ingredients/isopropyl-alcohol-and-triple-peptide-blend) - Work well together: [Arginine and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/arginine-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and GABA](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-gaba) - Work well together: [Silk amino acids and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/silk-amino-acids-and-hyaluronic-acid) - Work well together: [Taurine and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/taurine-and-hyaluronic-acid) - Work well together: [Hyaluronic acid and theanine](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-theanine) - Keep them apart: [Niacinamide and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/niacinamide-and-isopropyl-alcohol) - Work well together: [Panthenol and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/panthenol-and-hyaluronic-acid) - Keep them apart: [Vitamin C and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/vitamin-c-and-isopropyl-alcohol) - Keep them apart: [Benzoyl peroxide and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/benzoyl-peroxide-and-isopropyl-alcohol) - Work well together: [Vitamin C and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/vitamin-c-and-hyaluronic-acid) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/hyaluronic-acid-and-isopropyl-alcohol - United Kingdom: https://lovi.care/skincare/uk/ingredients/hyaluronic-acid-and-isopropyl-alcohol - Ireland: https://lovi.care/skincare/ie/ingredients/hyaluronic-acid-and-isopropyl-alcohol - Germany: https://lovi.care/skincare/de/ingredients/hyaluronic-acid-and-isopropyl-alcohol - France: https://lovi.care/skincare/fr/ingredients/hyaluronic-acid-and-isopropyl-alcohol - Italy: https://lovi.care/skincare/it/ingredients/hyaluronic-acid-and-isopropyl-alcohol - Netherlands: https://lovi.care/skincare/nl/ingredients/hyaluronic-acid-and-isopropyl-alcohol - Spain: https://lovi.care/skincare/es/ingredients/hyaluronic-acid-and-isopropyl-alcohol - Canada: https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-isopropyl-alcohol (this page) - Australia: https://lovi.care/skincare/au/ingredients/hyaluronic-acid-and-isopropyl-alcohol - Singapore: https://lovi.care/skincare/sg/ingredients/hyaluronic-acid-and-isopropyl-alcohol - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/hyaluronic-acid-and-isopropyl-alcohol - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/hyaluronic-acid-and-isopropyl-alcohol