# Glycolic acid and lactobionic acid

Page: https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-lactobionic-acid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Work well together

Use them together in your evening routine, applying [glycolic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid) first and [lactobionic acid](https://lovi.care/skincare/ca/ingredients/lactobionic-acid) second, for gentle exfoliation and soothing care. Glycolic acid smooths the skin while lactobionic acid adds moisture to calm potential irritation. If your skin feels sensitive, try a lower strength or use them on alternate nights.

[The use of polyhydroxy acids (PHAs) in photoaged skin](https://pubmed.ncbi.nlm.nih.gov/15002656/) [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/)

- [All about glycolic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid)
- [All about lactobionic acid](https://lovi.care/skincare/ca/ingredients/lactobionic-acid)

### [Glycolic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid) products

- [The Ordinary Glycolic Acid 7% Toning Solution](https://lovi.care/skincare/ca/p/the-ordinary/glycolic-acid-7-toning-solution/for/combination-skin) — Superior fit — [CA$15.80 at Amazon](https://www.amazon.ca/dp/B071914GGL?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [RoC Retinol Correxion Deep Wrinkle Night Cream](https://lovi.care/skincare/ca/p/roc/retinol-correxion-deep-wrinkle-night-cream/for/dark-spots) — High fit — [CA$42.99 at Amazon](https://www.amazon.ca/dp/B0FH5M1M1S?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [First Aid Beauty KP Bump Eraser Body Scrub](https://lovi.care/skincare/ca/p/first-aid-beauty/kp-bump-eraser-body-scrub/for/dark-spots) — Average fit — [CA$46.00 at Amazon](https://www.amazon.ca/dp/B0GSX4BHQ2?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [First Aid Beauty Facial Radiance Pads](https://lovi.care/skincare/ca/p/first-aid-beauty/facial-radiance-pads/for/sensitive-skin) — Superior fit — [CA$33.00 at Amazon](https://www.amazon.ca/dp/B0G2Z2VYW2?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Murad Rapid Dark Spot Correcting Serum](https://lovi.care/skincare/ca/p/murad/rapid-dark-spot-correcting-serum/for/acne-prone-skin) — High fit — [CA$118.00 at Amazon](https://www.amazon.ca/dp/B08KR79NBR?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Skinbetter Science AlphaRet Overnight Cream](https://lovi.care/skincare/ca/p/skinbetter-science/alpharet-overnight-cream/for/dry-sensitive-skin) — High fit
- [St. Ives Apricot Scrub](https://lovi.care/skincare/ca/p/st-ives/apricot-scrub/for/dry-skin) — Average fit
- [COSRX AHA/BHA Clarifying Treatment Toner](https://lovi.care/skincare/ca/p/cosrx/aha-bha-clarifying-treatment-toner/for/oily-acne-prone-skin) — Superior fit — [CA$20.40 at Amazon](https://www.amazon.ca/dp/B094PHCTHD?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Dr. Dennis Gross Alpha Beta Universal Daily Peel](https://lovi.care/skincare/ca/p/dr-dennis-gross/alpha-beta-universal-daily-peel/for/acne-prone-skin) — Superior fit — [CA$124.00 at Amazon](https://www.amazon.ca/dp/B0BM9PQGCS?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Pixi Glow Tonic](https://lovi.care/skincare/ca/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [CA$28.90 at Amazon](https://www.amazon.ca/dp/B09SN5B88W?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Good Molecules Overnight Exfoliating Treatment](https://lovi.care/skincare/ca/p/good-molecules/overnight-exfoliating-treatment/for/oily-skin) — Superior fit
- [CeraVe Skin Renewing Nightly Exfoliating Treatment](https://lovi.care/skincare/ca/p/cerave/skin-renewing-nightly-exfoliating-treatment/for/acne-prone-skin) — High fit — [CA$36.97 at Amazon](https://www.amazon.ca/dp/B0BQTMXTML?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)

### [Lactobionic acid](https://lovi.care/skincare/ca/ingredients/lactobionic-acid) products

- [Elemis Pro-Collagen Marine Moisture Essence](https://lovi.care/skincare/ca/p/elemis/pro-collagen-marine-moisture-essence/for/mature-skin) — Average fit
- [Elemis Pro-Collagen Tri-Acid Peel](https://lovi.care/skincare/ca/p/elemis/pro-collagen-tri-acid-peel/for/dark-spots) — High fit
- [Benton PHA Peeling Toner](https://lovi.care/skincare/ca/p/benton/pha-peeling-toner/for/dark-spots) — Superior fit
- [VT COSMETICS Cica Skin](https://lovi.care/skincare/ca/p/vt-cosmetics/cica-skin/for/sensitive-skin) — Superior fit — [CA$29.17 at Amazon](https://www.amazon.ca/dp/B0C2TQ24VY?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Estée Lauder Perfectly Clean Multi-Action Toning Lotion/Refiner](https://lovi.care/skincare/ca/p/estee-lauder/perfectly-clean-multi-action-toning-lotion-refiner/for/oily-skin) — High fit — [CA$48.00 at Amazon](https://www.amazon.ca/dp/B00CAUJJM8?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [COSRX Full Fit Propolis Synergy Pad](https://lovi.care/skincare/ca/p/cosrx/full-fit-propolis-synergy-pad/for/mature-skin) — High fit
- [MZ Skin Cleanse & Clarify Dual Action AHA Cleanser & Mask](https://lovi.care/skincare/ca/p/mz-skin/cleanse-and-clarify-dual-action-aha-cleanser-and-mask/for/acne-prone-skin) — High fit — [CA$119.95 at Amazon](https://www.amazon.ca/dp/B07D5J95NG?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [MZ Skin Radiance & Renewal Instant Clarity Refining Mask](https://lovi.care/skincare/ca/p/mz-skin/radiance-and-renewal-instant-clarity-refining-mask/for/oily-acne-prone-skin) — High fit

## Questions and answers

### Which goes first, glycolic acid or lactobionic acid?

[Glycolic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid) and [lactobionic acid](https://lovi.care/skincare/ca/ingredients/lactobionic-acid) work well together to provide gentle exfoliation and antioxidant protection. You can find both ingredients in products like Skintific AHA [BHA](https://lovi.care/skincare/ca/ingredients/salicylic-acid) PHA LHA Peeling Solution and Verb Ghost Exfoliating Scalp Nectar.

## Research on glycolic acid and lactobionic acid

- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Effects of lactobionic acid peel, aluminum oxide crystal microdermabrasion, and both procedures on skin hydration, elasticity, and transepidermal water loss](https://pubmed.ncbi.nlm.nih.gov/30661294/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Lactobionic acid · Journal of Cosmetic Dermatology, 2010
- [A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study](https://pubmed.ncbi.nlm.nih.gov/30859734/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019

## Other combinations

- Keep them apart: [Glycolic acid and benzoyl peroxide](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-benzoyl-peroxide)
- Keep them apart: [Glycolic acid and retinol](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-retinol)
- Depends on the strength: [Glycolic acid and niacinamide](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-niacinamide)
- Work well together: [Glycolic acid and sodium lactate](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-sodium-lactate)
- Work well together: [Glycolic acid and tromethamine](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-tromethamine)
- Depends on the strength: [Niacinamide and lactobionic acid](https://lovi.care/skincare/ca/ingredients/niacinamide-and-lactobionic-acid)
- Work well together: [Hyaluronic acid and lactobionic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-lactobionic-acid)
- Work well together: [Glycolic acid and betaine](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-betaine)
- Work well together: [Glycolic acid and glycerin](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-glycerin)
- Depends on the strength: [Glycolic acid and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-hyaluronic-acid)
- Keep them apart: [Glycolic acid and acetyl hexapeptide-3](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Glycolic acid and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-bio-placenta-peptides)
- Keep them apart: [Glycolic acid and carnosine](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-carnosine)
- Keep them apart: [Glycolic acid and collagen peptide](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-collagen-peptide)
- Keep them apart: [Glycolic acid and copper peptide](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-copper-peptide)
- Keep them apart: [Glycolic acid and hexapeptide](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-hexapeptide)
- Keep them apart: [Glycolic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-hexapeptide-9)
- Keep them apart: [Glycolic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Glycolic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Glycolic acid and peptide-rich plasma](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-peptide-rich-plasma)
- Keep them apart: [Glycolic acid and triple peptide blend](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-triple-peptide-blend)
- Keep them apart: [Adapalene and glycolic acid](https://lovi.care/skincare/ca/ingredients/adapalene-and-glycolic-acid)
- Keep them apart: [Glycolic acid and granactive retinoid](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-granactive-retinoid)
- Keep them apart: [Glycolic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Glycolic acid and pro-retinol](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-pro-retinol)
- Keep them apart: [Glycolic acid and retinal](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-retinal)
- Keep them apart: [Glycolic acid and retinoid blend](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-retinoid-blend)
- Keep them apart: [Glycolic acid and tretinoin](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-tretinoin)
- Work well together: [AHA blend glycolic and citric acids and lactobionic acid](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-lactobionic-acid)
- Work well together: [Lactobionic acid and citric acid](https://lovi.care/skincare/ca/ingredients/lactobionic-acid-and-citric-acid)
- Work well together: [Glycolic acid and gluconolactone](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-gluconolactone)
- Work well together: [Lactic acid and lactobionic acid](https://lovi.care/skincare/ca/ingredients/lactic-acid-and-lactobionic-acid)
- Work well together: [Mandelic acid and lactobionic acid](https://lovi.care/skincare/ca/ingredients/mandelic-acid-and-lactobionic-acid)
- Work well together: [Vitamin C and lactobionic acid](https://lovi.care/skincare/ca/ingredients/vitamin-c-and-lactobionic-acid)
- Work well together: [Glycolic acid and cholesterol](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-cholesterol)
- Work well together: [Glycolic acid and lauric acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-lauric-acid)
- Work well together: [Glycolic acid and linoleic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-linoleic-acid)
- Keep them apart: [Glycolic acid and tri-ceramide complex](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-tri-ceramide-complex)
- Work well together: [Glycolic acid and arginine](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-arginine)
- Work well together: [Glycolic acid and GABA](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-gaba)
- Work well together: [Glycolic acid and silk amino acids](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-silk-amino-acids)
- Work well together: [Glycolic acid and taurine](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-taurine)
- Work well together: [Glycolic acid and theanine](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-theanine)
- Work well together: [Salicylic acid and lactobionic acid](https://lovi.care/skincare/ca/ingredients/salicylic-acid-and-lactobionic-acid)
- Work well together: [Glycolic acid and ferulic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-ferulic-acid)
- Work well together: [Glycolic acid and vitamin E](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-vitamin-e)
- Keep them apart: [Glycolic acid and azelaic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-azelaic-acid)
- Keep them apart: [Glycolic acid and salicylic acid](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-salicylic-acid)
- Work well together: [Glycolic acid and allantoin](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-allantoin)
- Work well together: [Glycolic acid and bisabolol](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-bisabolol)
- Work well together: [Glycolic acid and panthenol](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-panthenol)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/glycolic-acid-and-lactobionic-acid
- United Kingdom: https://lovi.care/skincare/uk/ingredients/glycolic-acid-and-lactobionic-acid
- Ireland: https://lovi.care/skincare/ie/ingredients/glycolic-acid-and-lactobionic-acid
- Germany: https://lovi.care/skincare/de/ingredients/glycolic-acid-and-lactobionic-acid
- France: https://lovi.care/skincare/fr/ingredients/glycolic-acid-and-lactobionic-acid
- Italy: https://lovi.care/skincare/it/ingredients/glycolic-acid-and-lactobionic-acid
- Netherlands: https://lovi.care/skincare/nl/ingredients/glycolic-acid-and-lactobionic-acid
- Spain: https://lovi.care/skincare/es/ingredients/glycolic-acid-and-lactobionic-acid
- Canada: https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-lactobionic-acid (this page)
- Australia: https://lovi.care/skincare/au/ingredients/glycolic-acid-and-lactobionic-acid
- Singapore: https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-lactobionic-acid
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/glycolic-acid-and-lactobionic-acid
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/glycolic-acid-and-lactobionic-acid