# Ceramide-building complex and hexapeptide-9 Page: https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-hexapeptide-9 The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada. Work well together Use them together in the same routine, applying the [ceramide-building complex](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex) first and the [hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hexapeptide-9) right after, because the lipids help the peptide sink in better. The rich lipids make the peptides work better so your skin barrier feels stronger and looks smoother. If your skin feels too heavy, you can wait a few extra minutes between applying them or use a lighter cream. - [All about ceramide-building complex](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex) - [All about hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hexapeptide-9) ### [Ceramide-building complex](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex) products - [Dermalogica Stabilizing Repair Cream](https://lovi.care/skincare/ca/p/dermalogica/stabilizing-repair-cream/for/dry-skin) — Superior fit — [CA$104.00 at Amazon](https://www.amazon.ca/dp/B0CF411BXQ?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) ### [Hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hexapeptide-9) products - [Elemis Pro-Collagen Night Cream](https://lovi.care/skincare/ca/p/elemis/pro-collagen-night-cream/for/dry-sensitive-skin) — Superior fit — [CA$131.00 at Sephora](https://www.sephora.com/ca/en/product/elemis-pro-collagen-anti-aging-night-cream-P514133?skuId=2828507) - [Murad Cellular Hydration Repair Serum](https://lovi.care/skincare/ca/p/murad/cellular-hydration-repair-serum/for/acne-prone-skin) — High fit - [MARY & MAY 6 Peptide Complex Serum](https://lovi.care/skincare/ca/p/mary-and-may/6-peptide-complex-serum/for/mature-skin) — High fit — [CA$28.99 at Amazon](https://www.amazon.ca/dp/B095YHYF33?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) ## Questions and answers ### Can you use ceramide-building complex and hexapeptide-9 together? Yes, [ceramide-building complex](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex) and [hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hexapeptide-9) work well together to help enhance skin repair and barrier support. The lipids improve peptide absorption while reinforcing the skin structure. ### Which goes first, ceramide-building complex or hexapeptide-9? Ceramide-building complex and hexapeptide-9 work well together, and lipids such as ceramides help improve peptide absorption while reinforcing skin structure. ### Are ceramide-building complex and hexapeptide-9 good for sensitive skin? Ceramide-building complex and hexapeptide-9 are a great combination to help repair and support the skin barrier. Lovi rates their fit as superior for dry, mature, and barrier-impaired skin types. ## Research on ceramide-building complex and hexapeptide-9 - [Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/40586182/) Hexapeptide-9 · Journal of Cosmetic Dermatology, 2025 ## Other combinations - Work well together: [Benzoyl peroxide and ceramide-building complex](https://lovi.care/skincare/ca/ingredients/benzoyl-peroxide-and-ceramide-building-complex) - Keep them apart: [Adapalene and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/adapalene-and-hexapeptide-9) - Keep them apart: [Granactive retinoid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/granactive-retinoid-and-hexapeptide-9) - Keep them apart: [Hydroxypinacolone retinoate and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hydroxypinacolone-retinoate-and-hexapeptide-9) - Keep them apart: [Pro-retinol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/pro-retinol-and-hexapeptide-9) - Keep them apart: [Retinal and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/retinal-and-hexapeptide-9) - Keep them apart: [Retinoid blend and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/retinoid-blend-and-hexapeptide-9) - Depends on the strength: [Retinol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/retinol-and-hexapeptide-9) - Keep them apart: [Tretinoin and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/tretinoin-and-hexapeptide-9) - Keep them apart: [Vitamin A and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/vitamin-a-and-hexapeptide-9) - Work well together: [Liposome and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/liposome-and-hexapeptide-9) - Work well together: [Microcapsule and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/microcapsule-and-hexapeptide-9) - Depends on the strength: [Vitamin C and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/vitamin-c-and-hexapeptide-9) - Work well together: [Betaine and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/betaine-and-hexapeptide-9) - Work well together: [Glycerin and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/glycerin-and-hexapeptide-9) - Work well together: [Hyaluronic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid-and-hexapeptide-9) - Depends on the strength: [Niacinamide and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/niacinamide-and-hexapeptide-9) - Work well together: [Panthenol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/panthenol-and-hexapeptide-9) - Work well together: [Bakuchiol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/bakuchiol-and-hexapeptide-9) - Work well together: [Arginine and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/arginine-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and GABA](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-gaba) - Work well together: [Silk amino acids and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/silk-amino-acids-and-hexapeptide-9) - Work well together: [Taurine and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/taurine-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and theanine](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-theanine) - Keep them apart: [AHA blend glycolic and citric acids and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide-9) - Keep them apart: [Citric acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/citric-acid-and-hexapeptide-9) - Keep them apart: [Glycolic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-hexapeptide-9) - Keep them apart: [Lactic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/lactic-acid-and-hexapeptide-9) - Keep them apart: [Mandelic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/mandelic-acid-and-hexapeptide-9) - Work well together: [Coenzyme Q10 and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/coenzyme-q10-and-hexapeptide-9) - Work well together: [Green tea and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/green-tea-and-hexapeptide-9) - Work well together: [Vitamin E and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/vitamin-e-and-hexapeptide-9) - Work well together: [Ceramide-building complex and acetyl hexapeptide-3](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-acetyl-hexapeptide-3) - Work well together: [Ceramide-building complex and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-bio-placenta-peptides) - Work well together: [Ceramide-building complex and collagen peptide](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-collagen-peptide) - Work well together: [Ceramide-building complex and copper peptide](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-copper-peptide) - Work well together: [Ceramide-building complex and hexapeptide](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-hexapeptide) - Work well together: [Hexapeptide-9 and beta-sitosterol](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-beta-sitosterol) - Work well together: [Cholesterol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/cholesterol-and-hexapeptide-9) - Work well together: [Phytosphingosine and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/phytosphingosine-and-hexapeptide-9) - Work well together: [Phytosterol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/phytosterol-and-hexapeptide-9) - Work well together: [Hexapeptide-9 and squalene](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-squalene) - Work well together: [Hexapeptide-9 and tri-ceramide complex](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-tri-ceramide-complex) - Work well together: [Ceramide-building complex and palmitoyl pentapeptide-4](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-palmitoyl-pentapeptide-4) - Work well together: [Ceramide-building complex and palmitoyl tripeptide-1](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-palmitoyl-tripeptide-1) - Work well together: [Ceramide-building complex and peptide-rich plasma](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-peptide-rich-plasma) - Work well together: [Ceramide-building complex and triple peptide blend](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-triple-peptide-blend) - Keep them apart: [Salicylic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/salicylic-acid-and-hexapeptide-9) - Keep them apart: [Hexapeptide-9 and baking soda](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-baking-soda) - Keep them apart: [Bleach and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/bleach-and-hexapeptide-9) - Keep them apart: [Potassium hydroxide and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/potassium-hydroxide-and-hexapeptide-9) - Keep them apart: [Hexapeptide-9 and behenyl alcohol](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-behenyl-alcohol) - Keep them apart: [Hexapeptide-9 and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-isopropyl-alcohol) - Keep them apart: [Polyvinyl alcohol and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/polyvinyl-alcohol-and-hexapeptide-9) - Keep them apart: [Copper and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/copper-and-hexapeptide-9) - Keep them apart: [Benzoyl peroxide and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/benzoyl-peroxide-and-hexapeptide-9) - Keep them apart: [Magnesium and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/magnesium-and-hexapeptide-9) - Keep them apart: [Zinc and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/zinc-and-hexapeptide-9) - Keep them apart: [Zinc sulfate and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/zinc-sulfate-and-hexapeptide-9) - Work well together: [Retinol and ceramide-building complex](https://lovi.care/skincare/ca/ingredients/retinol-and-ceramide-building-complex) - Keep them apart: [Azelaic acid and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/azelaic-acid-and-hexapeptide-9) - Keep them apart: [Hexapeptide-9 and protease](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-protease) - Keep them apart: [Superoxide dismutase and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/superoxide-dismutase-and-hexapeptide-9) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/ceramide-building-complex-and-hexapeptide-9 - United Kingdom: https://lovi.care/skincare/uk/ingredients/ceramide-building-complex-and-hexapeptide-9 - Ireland: https://lovi.care/skincare/ie/ingredients/ceramide-building-complex-and-hexapeptide-9 - Germany: https://lovi.care/skincare/de/ingredients/ceramide-building-complex-and-hexapeptide-9 - France: https://lovi.care/skincare/fr/ingredients/ceramide-building-complex-and-hexapeptide-9 - Italy: https://lovi.care/skincare/it/ingredients/ceramide-building-complex-and-hexapeptide-9 - Netherlands: https://lovi.care/skincare/nl/ingredients/ceramide-building-complex-and-hexapeptide-9 - Spain: https://lovi.care/skincare/es/ingredients/ceramide-building-complex-and-hexapeptide-9 - Canada: https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-hexapeptide-9 (this page) - Australia: https://lovi.care/skincare/au/ingredients/ceramide-building-complex-and-hexapeptide-9 - Singapore: https://lovi.care/skincare/sg/ingredients/ceramide-building-complex-and-hexapeptide-9 - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/ceramide-building-complex-and-hexapeptide-9 - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/ceramide-building-complex-and-hexapeptide-9