# Bio-placenta peptides and protease

Page: https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-protease

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Keep them apart

Use them at different times of day, applying the [protease](https://lovi.care/skincare/ca/ingredients/protease) first and the [bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides) later, because they clash and neutralize each other. The protease enzyme breaks down the bio-placenta peptides, preventing them from firming and smoothing your skin as intended. You can change your routine by using one in the morning and the other at night to keep both effective.

- [All about bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides)
- [All about protease](https://lovi.care/skincare/ca/ingredients/protease)

### [Bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides) products

- [LION POSE PEP TALK](https://lovi.care/skincare/ca/p/lion-pose/pep-talk/for/dry-skin) — Average fit

### [Protease](https://lovi.care/skincare/ca/ingredients/protease) products

- [COSRX Centella Cleansing Powder](https://lovi.care/skincare/ca/p/cosrx/centella-cleansing-powder/for/combination-skin) — Superior fit
- [FANCL Deep Clear Washing Powder](https://lovi.care/skincare/ca/p/fancl/deep-clear-washing-powder/for/oily-skin) — High fit

## Questions and answers

### Can you use bio-placenta peptides and protease together?

No, you should keep [bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides) and [protease](https://lovi.care/skincare/ca/ingredients/protease) apart in your routine. Proteases degrade peptide bonds and can render the peptides inactive.

### Which goes first, bio-placenta peptides or protease?

Keep bio-placenta peptides and protease apart in your routine because mixing them may degrade the peptide bonds and render the actives inactive.

### Are bio-placenta peptides and protease good for sensitive skin?

Bio-placenta peptides and protease should be kept apart in your routine because the protease degrades the peptides and renders them inactive. There are no specific products on this page containing both of these ingredients.

## Research on bio-placenta peptides and protease

- [Preparation and functional evaluation of collagen oligopeptide-rich hydrolysate from fish skin with the serine collagenolytic protease from Pseudoalteromonas sp. SM9913](https://pubmed.ncbi.nlm.nih.gov/29146927/) Protease · Scientific Reports, 2017

## Other combinations

- Keep them apart: [Adapalene and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/adapalene-and-bio-placenta-peptides)
- Keep them apart: [Bio-placenta peptides and granactive retinoid](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-granactive-retinoid)
- Keep them apart: [Bio-placenta peptides and hydroxypinacolone retinoate](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-hydroxypinacolone-retinoate)
- Keep them apart: [Bio-placenta peptides and pro-retinol](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-pro-retinol)
- Keep them apart: [Bio-placenta peptides and retinal](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-retinal)
- Keep them apart: [Bio-placenta peptides and retinoid blend](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-retinoid-blend)
- Depends on the strength: [Retinol and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/retinol-and-bio-placenta-peptides)
- Keep them apart: [Tretinoin and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/tretinoin-and-bio-placenta-peptides)
- Keep them apart: [Bio-placenta peptides and vitamin A](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-vitamin-a)
- Work well together: [Bio-placenta peptides and liposome](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-liposome)
- Work well together: [Bio-placenta peptides and microcapsule](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-microcapsule)
- Keep them apart: [Vitamin C and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/vitamin-c-and-bio-placenta-peptides)
- Work well together: [Bio-placenta peptides and betaine](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-betaine)
- Work well together: [Glycerin and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/glycerin-and-bio-placenta-peptides)
- Work well together: [Bio-placenta peptides and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-hyaluronic-acid)
- Depends on the strength: [Niacinamide and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/niacinamide-and-bio-placenta-peptides)
- Work well together: [Panthenol and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/panthenol-and-bio-placenta-peptides)
- Work well together: [Bio-placenta peptides and bakuchiol](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-bakuchiol)
- Work well together: [Bio-placenta peptides and arginine](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-arginine)
- Work well together: [Bio-placenta peptides and GABA](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-gaba)
- Work well together: [Bio-placenta peptides and silk amino acids](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-silk-amino-acids)
- Work well together: [Bio-placenta peptides and taurine](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-taurine)
- Work well together: [Bio-placenta peptides and theanine](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-bio-placenta-peptides)
- Keep them apart: [Bio-placenta peptides and citric acid](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-citric-acid)
- Keep them apart: [Glycolic acid and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/glycolic-acid-and-bio-placenta-peptides)
- Keep them apart: [Bio-placenta peptides and lactic acid](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-lactic-acid)
- Keep them apart: [Bio-placenta peptides and mandelic acid](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-mandelic-acid)
- Work well together: [Bio-placenta peptides and coenzyme q10](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-coenzyme-q10)
- Work well together: [Green tea and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/green-tea-and-bio-placenta-peptides)
- Work well together: [Bio-placenta peptides and vitamin E](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-vitamin-e)
- Work well together: [Bio-placenta peptides and beta-sitosterol](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/ceramide-building-complex-and-bio-placenta-peptides)
- Work well together: [Bio-placenta peptides and cholesterol](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-cholesterol)
- Work well together: [Bio-placenta peptides and phytosphingosine](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-phytosphingosine)
- Work well together: [Bio-placenta peptides and phytosterol](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-phytosterol)
- Work well together: [Bio-placenta peptides and squalene](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-squalene)
- Work well together: [Bio-placenta peptides and tri-ceramide complex](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-tri-ceramide-complex)
- Keep them apart: [Salicylic acid and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/salicylic-acid-and-bio-placenta-peptides)
- Keep them apart: [Bio-placenta peptides and baking soda](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-baking-soda)
- Keep them apart: [Bio-placenta peptides and bleach](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-bleach)
- Keep them apart: [Bio-placenta peptides and potassium hydroxide](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-potassium-hydroxide)
- Keep them apart: [Bio-placenta peptides and behenyl alcohol](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-behenyl-alcohol)
- Keep them apart: [Bio-placenta peptides and isopropyl alcohol](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-isopropyl-alcohol)
- Keep them apart: [Bio-placenta peptides and polyvinyl alcohol](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-polyvinyl-alcohol)
- Keep them apart: [Bio-placenta peptides and copper](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-copper)
- Keep them apart: [Bio-placenta peptides and magnesium](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-magnesium)
- Keep them apart: [Bio-placenta peptides and zinc](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-zinc)
- Keep them apart: [Bio-placenta peptides and zinc sulfate](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-zinc-sulfate)
- Keep them apart: [Benzoyl peroxide and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/benzoyl-peroxide-and-bio-placenta-peptides)
- Keep them apart: [Azelaic acid and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/azelaic-acid-and-bio-placenta-peptides)
- Keep them apart: [Acetyl hexapeptide-3 and protease](https://lovi.care/skincare/ca/ingredients/acetyl-hexapeptide-3-and-protease)
- Keep them apart: [Bio-placenta peptides and superoxide dismutase](https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-superoxide-dismutase)
- Keep them apart: [Collagen peptide and protease](https://lovi.care/skincare/ca/ingredients/collagen-peptide-and-protease)
- Keep them apart: [Copper peptide and protease](https://lovi.care/skincare/ca/ingredients/copper-peptide-and-protease)
- Keep them apart: [Hexapeptide and protease](https://lovi.care/skincare/ca/ingredients/hexapeptide-and-protease)
- Keep them apart: [Hexapeptide-9 and protease](https://lovi.care/skincare/ca/ingredients/hexapeptide-9-and-protease)
- Keep them apart: [Protease and palmitoyl pentapeptide-4](https://lovi.care/skincare/ca/ingredients/protease-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Protease and palmitoyl tripeptide-1](https://lovi.care/skincare/ca/ingredients/protease-and-palmitoyl-tripeptide-1)
- Keep them apart: [Peptide-rich plasma and protease](https://lovi.care/skincare/ca/ingredients/peptide-rich-plasma-and-protease)
- Keep them apart: [Protease and triple peptide blend](https://lovi.care/skincare/ca/ingredients/protease-and-triple-peptide-blend)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/bio-placenta-peptides-and-protease
- United Kingdom: https://lovi.care/skincare/uk/ingredients/bio-placenta-peptides-and-protease
- Ireland: https://lovi.care/skincare/ie/ingredients/bio-placenta-peptides-and-protease
- Germany: https://lovi.care/skincare/de/ingredients/bio-placenta-peptides-and-protease
- France: https://lovi.care/skincare/fr/ingredients/bio-placenta-peptides-and-protease
- Italy: https://lovi.care/skincare/it/ingredients/bio-placenta-peptides-and-protease
- Netherlands: https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-protease
- Spain: https://lovi.care/skincare/es/ingredients/bio-placenta-peptides-and-protease
- Canada: https://lovi.care/skincare/ca/ingredients/bio-placenta-peptides-and-protease (this page)
- Australia: https://lovi.care/skincare/au/ingredients/bio-placenta-peptides-and-protease
- Singapore: https://lovi.care/skincare/sg/ingredients/bio-placenta-peptides-and-protease
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/bio-placenta-peptides-and-protease
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/bio-placenta-peptides-and-protease
