# Adapalene and aha blend glycolic and citric acids Page: https://lovi.care/skincare/ca/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada. Keep them apart Use them on alternate nights because they are both strong and can irritate skin when combined. Both ingredients work hard to renew the skin, but using them together can cause redness, dryness, and a damaged barrier. To fix this, you can try a gentler strength or space them out on different nights. [Retinoids: a journey from the molecular structures and mechanisms of action to clinical uses in dermatology and adverse effects](https://pubmed.ncbi.nlm.nih.gov/28318351/) [Why Topical Retinoids Are Mainstay of Therapy for Acne](https://pubmed.ncbi.nlm.nih.gov/28585191/) - [All about adapalene](https://lovi.care/skincare/ca/ingredients/adapalene) - [All about aha blend glycolic and citric acids](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids) ### [Adapalene](https://lovi.care/skincare/ca/ingredients/adapalene) products - [Differin Gel](https://lovi.care/skincare/ca/p/differin/gel/for/oily-acne-prone-skin) — High fit - [Galderma Epiduo Gel](https://lovi.care/skincare/ca/p/galderma/epiduo-gel/for/acne-prone-skin) — High fit - [La Roche-Posay Effaclar Adapalene Gel 0.1% Acne Treatment](https://lovi.care/skincare/ca/p/la-roche-posay/effaclar-adapalene-gel-0-1-acne-treatment/for/oily-skin) — Superior fit ### [AHA blend glycolic and citric acids](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids) products - [Dior DreamSkin 1-Minute Mask](https://lovi.care/skincare/ca/p/dior/dreamskin-1-minute-mask/for/dark-spots) — Average fit — [CA$178.95 at Amazon](https://www.amazon.ca/dp/B0BH8CM921?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) ## Questions and answers ### Can you use adapalene and aha blend glycolic and citric acids together? Keep [adapalene](https://lovi.care/skincare/ca/ingredients/adapalene) and the AHA blend of glycolic and [citric acids](https://lovi.care/skincare/ca/ingredients/citric-acid) apart, using them on alternate evenings or the AHA in the morning to prevent irritation. ### Which goes first, adapalene or aha blend glycolic and citric acids? Keep adapalene and the AHA blend of glycolic and citric acids apart by using them at different times, such as AHAs in the morning or on alternate nights and retinoids on alternate evenings, to avoid irritation and barrier disruption. ### Are adapalene and aha blend glycolic and citric acids good for sensitive skin? Keep adapalene and the [AHA blend glycolic and citric acids](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids) apart because sensitive skin may experience irritation or barrier disruption when they are layered together in the same routine. Alternate their use by applying AHAs in the morning or on separate evenings from adapalene. ## Research on adapalene and aha blend glycolic and citric acids - [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene · American Journal of Clinical Dermatology, 2018 - [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Adapalene · American Journal of Clinical Dermatology, 2022 - [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene · Archives of Dermatological Research, 2022 - [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) AHA blend glycolic and citric acids · Clinical, Cosmetic and Investigational Dermatology, 2019 - [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023 ## Other combinations - Keep them apart: [Benzoyl peroxide and aha blend glycolic and citric acids](https://lovi.care/skincare/ca/ingredients/benzoyl-peroxide-and-aha-blend-glycolic-and-citric-acids) - Keep them apart: [Retinol and aha blend glycolic and citric acids](https://lovi.care/skincare/ca/ingredients/retinol-and-aha-blend-glycolic-and-citric-acids) - Depends on the strength: [AHA blend glycolic and citric acids and niacinamide](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-niacinamide) - Work well together: [AHA blend glycolic and citric acids and sodium lactate](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-sodium-lactate) - Work well together: [AHA blend glycolic and citric acids and tromethamine](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-tromethamine) - Keep them apart: [Adapalene and acetyl hexapeptide-3](https://lovi.care/skincare/ca/ingredients/adapalene-and-acetyl-hexapeptide-3) - Keep them apart: [Adapalene and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/adapalene-and-bio-placenta-peptides) - Keep them apart: [Adapalene and collagen peptide](https://lovi.care/skincare/ca/ingredients/adapalene-and-collagen-peptide) - Keep them apart: [Adapalene and copper peptide](https://lovi.care/skincare/ca/ingredients/adapalene-and-copper-peptide) - Keep them apart: [Adapalene and hexapeptide](https://lovi.care/skincare/ca/ingredients/adapalene-and-hexapeptide) - Keep them apart: [Adapalene and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/adapalene-and-hexapeptide-9) - Keep them apart: [Adapalene and palmitoyl pentapeptide-4](https://lovi.care/skincare/ca/ingredients/adapalene-and-palmitoyl-pentapeptide-4) - Keep them apart: [Adapalene and palmitoyl tripeptide-1](https://lovi.care/skincare/ca/ingredients/adapalene-and-palmitoyl-tripeptide-1) - Keep them apart: [Adapalene and peptide-rich plasma](https://lovi.care/skincare/ca/ingredients/adapalene-and-peptide-rich-plasma) - Keep them apart: [Adapalene and triple peptide blend](https://lovi.care/skincare/ca/ingredients/adapalene-and-triple-peptide-blend) - Depends on the strength: [Adapalene and niacinamide](https://lovi.care/skincare/ca/ingredients/adapalene-and-niacinamide) - Work well together: [AHA blend glycolic and citric acids and betaine](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-betaine) - Work well together: [AHA blend glycolic and citric acids and glycerin](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-glycerin) - Depends on the strength: [AHA blend glycolic and citric acids and hyaluronic acid](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-hyaluronic-acid) - Keep them apart: [AHA blend glycolic and citric acids and acetyl hexapeptide-3](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-acetyl-hexapeptide-3) - Keep them apart: [AHA blend glycolic and citric acids and bio-placenta peptides](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-bio-placenta-peptides) - Keep them apart: [AHA blend glycolic and citric acids and carnosine](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-carnosine) - Keep them apart: [AHA blend glycolic and citric acids and collagen peptide](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-collagen-peptide) - Keep them apart: [AHA blend glycolic and citric acids and copper peptide](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-copper-peptide) - Keep them apart: [AHA blend glycolic and citric acids and hexapeptide](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide) - Keep them apart: [AHA blend glycolic and citric acids and hexapeptide-9](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide-9) - Keep them apart: [AHA blend glycolic and citric acids and palmitoyl pentapeptide-4](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-palmitoyl-pentapeptide-4) - Keep them apart: [AHA blend glycolic and citric acids and palmitoyl tripeptide-1](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-palmitoyl-tripeptide-1) - Keep them apart: [AHA blend glycolic and citric acids and peptide-rich plasma](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-peptide-rich-plasma) - Keep them apart: [AHA blend glycolic and citric acids and triple peptide blend](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-triple-peptide-blend) - Keep them apart: [AHA blend glycolic and citric acids and granactive retinoid](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-granactive-retinoid) - Keep them apart: [AHA blend glycolic and citric acids and hydroxypinacolone retinoate](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-hydroxypinacolone-retinoate) - Keep them apart: [AHA blend glycolic and citric acids and pro-retinol](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-pro-retinol) - Keep them apart: [AHA blend glycolic and citric acids and retinal](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-retinal) - Keep them apart: [AHA blend glycolic and citric acids and retinoid blend](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-retinoid-blend) - Keep them apart: [AHA blend glycolic and citric acids and tretinoin](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-tretinoin) - Keep them apart: [Adapalene and citric acid](https://lovi.care/skincare/ca/ingredients/adapalene-and-citric-acid) - Keep them apart: [Adapalene and glycolic acid](https://lovi.care/skincare/ca/ingredients/adapalene-and-glycolic-acid) - Keep them apart: [Adapalene and lactic acid](https://lovi.care/skincare/ca/ingredients/adapalene-and-lactic-acid) - Keep them apart: [Adapalene and mandelic acid](https://lovi.care/skincare/ca/ingredients/adapalene-and-mandelic-acid) - Work well together: [AHA blend glycolic and citric acids and gluconolactone](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-gluconolactone) - Work well together: [AHA blend glycolic and citric acids and lactobionic acid](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-lactobionic-acid) - Work well together: [AHA blend glycolic and citric acids and cholesterol](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-cholesterol) - Work well together: [AHA blend glycolic and citric acids and lauric acid](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-lauric-acid) - Work well together: [AHA blend glycolic and citric acids and linoleic acid](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-linoleic-acid) - Keep them apart: [AHA blend glycolic and citric acids and tri-ceramide complex](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-tri-ceramide-complex) - Work well together: [AHA blend glycolic and citric acids and arginine](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-arginine) - Work well together: [AHA blend glycolic and citric acids and GABA](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-gaba) - Work well together: [AHA blend glycolic and citric acids and silk amino acids](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-silk-amino-acids) - Work well together: [AHA blend glycolic and citric acids and taurine](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-taurine) - Work well together: [AHA blend glycolic and citric acids and theanine](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-theanine) - Keep them apart: [Adapalene and salicylic acid](https://lovi.care/skincare/ca/ingredients/adapalene-and-salicylic-acid) - Keep them apart: [Adapalene and vitamin C](https://lovi.care/skincare/ca/ingredients/adapalene-and-vitamin-c) - Work well together: [AHA blend glycolic and citric acids and ferulic acid](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-ferulic-acid) - Work well together: [AHA blend glycolic and citric acids and vitamin E](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-vitamin-e) - Keep them apart: [Azelaic acid and aha blend glycolic and citric acids](https://lovi.care/skincare/ca/ingredients/azelaic-acid-and-aha-blend-glycolic-and-citric-acids) - Keep them apart: [AHA blend glycolic and citric acids and salicylic acid](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-salicylic-acid) - Keep them apart: [Adapalene and benzoyl peroxide](https://lovi.care/skincare/ca/ingredients/adapalene-and-benzoyl-peroxide) - Work well together: [AHA blend glycolic and citric acids and allantoin](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-allantoin) - Work well together: [AHA blend glycolic and citric acids and bisabolol](https://lovi.care/skincare/ca/ingredients/aha-blend-glycolic-and-citric-acids-and-bisabolol) - Work well together: [Panthenol and aha blend glycolic and citric acids](https://lovi.care/skincare/ca/ingredients/panthenol-and-aha-blend-glycolic-and-citric-acids) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - United Kingdom: https://lovi.care/skincare/uk/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - Ireland: https://lovi.care/skincare/ie/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - Germany: https://lovi.care/skincare/de/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - France: https://lovi.care/skincare/fr/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - Italy: https://lovi.care/skincare/it/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - Netherlands: https://lovi.care/skincare/nl/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - Spain: https://lovi.care/skincare/es/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - Canada: https://lovi.care/skincare/ca/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids (this page) - Australia: https://lovi.care/skincare/au/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - Singapore: https://lovi.care/skincare/sg/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/adapalene-and-aha-blend-glycolic-and-citric-acids