# Sesderma vs Theramid

Page: https://lovi.care/skincare/ca/compare/sesderma-vs-theramid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Sesderma and Theramid are Spanish skincare brands known for meticulously engineered formulas that support various complexions. The former delivers advanced [serums](https://lovi.care/skincare/ca/ingredients/serum) featuring botanical [extracts](https://lovi.care/skincare/ca/ingredients/extract) and active compounds tailored for sensitive, hyperpigmented, and aging skin types. Meanwhile, the latter provides advanced moisturizers and targeted serums that suit balanced, dry, combination, oily, and sensitive skin best. While both offer specialized treatments, they differ in their specific standout offerings and founding histories.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

Theramid is a Spanish skincare brand founded in 2022 and owned by Cosnova Group since 2026.

[cosmeticsbusiness.com](https://cosmeticsbusiness.com/cosnova-acquires-niche-beauty-labs-expand-skin-care)

This page compares some of the most popular Sesderma and Theramid products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg5b4e4661ce).

### Popular Sesderma vs Theramid products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/ca/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit

#### Theramid

- [Copper Peptide](https://lovi.care/skincare/ca/p/theramid/copper-peptide/for/oily-skin) — High fit
- [DERMA-PEPTIDES](https://lovi.care/skincare/ca/p/theramid/derma-peptides/for/mature-skin) — High fit
- [Ceramide Treatment](https://lovi.care/skincare/ca/p/theramid/ceramide-treatment/for/dry-sensitive-skin) — Superior fit

## Questions and answers

### Sesderma or Theramid: which is better?

Theramid is a better choice for fragrance-sensitive shoppers since the products on this page list no fragrance, whereas Sesderma includes fragrance. For dry sensitive skin, Theramid reaches a Superior fit with its Ceramide Treatment.

[Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

### What is the difference between Sesderma and Theramid?

Theramid offers fragrance-free [serums](https://lovi.care/skincare/ca/ingredients/serum) and moisturizers, whereas Sesderma includes fragrance in its Azelac RU Serum. For dry sensitive skin, Theramid reaches a Superior fit level with its Ceramide Treatment, while Sesderma falls to a Low fit level for that same skin type.

[Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

### Which is more affordable, Sesderma or Theramid?

Neither Sesderma nor Theramid is listed with pricing on this page, so affordability cannot be compared here. Lovi shows the products on this page for both brands, but price details are not included.

### Which causes fewer breakouts, Sesderma or Theramid?

Theramid has a High Lovi fit for acne-prone skin with its Ceramide Treatment, whereas the Sesderma serum on this page has an Average fit.

[Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

### When were Sesderma and Theramid founded and who owns them?

Sesderma was founded in 1989 in Spain and is owned by Grupo Sesderma, while Theramid was founded in 2022 in Spain and is owned by Cosnova Group.

### Do Sesderma and Theramid products contain fragrance?

Theramid products on this page contain no fragrance. In contrast, the Sesderma product on this page includes fragrance.

### What do reviewers say about Theramid moisturizers?

Reviewers mostly mention that Theramid moisturizers are restorative and soothing. However, they also often note formulation and compatibility issues with the products on this page.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Madecassic acid · Indian Journal of Pharmaceutical Sciences, 2016
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramide · Scientific Reports, 2022
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin, Madecassic acid · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassic acid · Journal of Alternative and Complementary Medicine, 2020
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica · Molecules, 2023
- [The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro](https://pubmed.ncbi.nlm.nih.gov/37218728/) Bifida lysate ferment · Journal of Cosmetic Dermatology, 2023
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Positive and ecobiological contribution in skin photoprotection of ectoine and mannitol combined in vivo with UV filters](https://pubmed.ncbi.nlm.nih.gov/37539499/) Ectoin · Journal of Cosmetic Dermatology, 2024
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu](https://pubmed.ncbi.nlm.nih.gov/42573538/) Copper tripeptide-1 · Skin Research and Technology, 2026
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · International Journal of Cosmetic Science, 2026

## The brands

- Spanish skincare: [Sesderma](https://lovi.care/skincare/ca/brands/sesderma)
- Spanish skincare: [Theramid](https://lovi.care/skincare/ca/brands/theramid)

## More comparisons

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- [CeraVe vs Sesderma](https://lovi.care/skincare/ca/compare/cerave-vs-sesderma)
- [CeraVe vs Theramid](https://lovi.care/skincare/ca/compare/cerave-vs-theramid)
- [La Roche-Posay vs Sesderma](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-sesderma)
- [La Roche-Posay vs Theramid](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-theramid)
- [Dr. Althea vs Sesderma](https://lovi.care/skincare/ca/compare/dr-althea-vs-sesderma)
- [Dr. Althea vs Theramid](https://lovi.care/skincare/ca/compare/dr-althea-vs-theramid)
- [Some By Mi vs Sesderma](https://lovi.care/skincare/ca/compare/some-by-mi-vs-sesderma)
- [Some By Mi vs Theramid](https://lovi.care/skincare/ca/compare/some-by-mi-vs-theramid)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/sesderma-vs-theramid
- United Kingdom: https://lovi.care/skincare/uk/compare/sesderma-vs-theramid
- Ireland: https://lovi.care/skincare/ie/compare/sesderma-vs-theramid
- Germany: https://lovi.care/skincare/de/compare/sesderma-vs-theramid
- France: https://lovi.care/skincare/fr/compare/sesderma-vs-theramid
- Italy: https://lovi.care/skincare/it/compare/sesderma-vs-theramid
- Netherlands: https://lovi.care/skincare/nl/compare/sesderma-vs-theramid
- Spain: https://lovi.care/skincare/es/compare/sesderma-vs-theramid
- Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-theramid (this page)
- Australia: https://lovi.care/skincare/au/compare/sesderma-vs-theramid
- Singapore: https://lovi.care/skincare/sg/compare/sesderma-vs-theramid
- Saudi Arabia: https://lovi.care/skincare/sa/compare/sesderma-vs-theramid
- United Arab Emirates: https://lovi.care/skincare/ae/compare/sesderma-vs-theramid