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Sesderma vs ISDIN Isdinceutics

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

Sesderma and ISDIN Isdinceutics are two established Spanish skincare brands founded in 1989 and 1975, respectively. The first brand is beloved for advanced serums like the Azelac RU Serum, while the second brand is revered for targeted eye products such as K-Ox Eyes. Both options feature meticulously engineered formulas, with the first brand suiting sensitive, hyperpigmented, and aging skin best, and the second brand suiting mature, dry, and sensitive skin best. They differ primarily in their standout formulations, botanical extracts, and active compounds that address specific concerns like dark circles, puffiness, and acne-prone skin.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

ISDIN Isdinceutics is a Spanish skincare brand founded in 1975 and owned by Puig since 2027.

puig.com

This page compares some of the most popular Sesderma and ISDIN Isdinceutics products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Sesderma vs ISDIN Isdinceutics products

Questions and answers

Sesderma or ISDIN Isdinceutics: which is better?

Neither brand is universally better, as they offer different products for different concerns on this page. For acne-prone and dark spots, Sesderma's Azelac RU Serum has a High Lovi fit, while ISDIN Isdinceutics' K-Ox Eyes achieves a High Lovi fit for mature and sensitive skin.

What is the difference between Sesderma and ISDIN Isdinceutics?

Sesderma and ISDIN Isdinceutics are both Spanish skincare brands founded decades ago, but they offer entirely different products on this page for specific concerns. Sesderma features Azelac RU Serum, which achieves a High Lovi fit for acne-prone skin and dark spots, while ISDIN Isdinceutics offers K-Ox Eyes, which has a High Lovi fit for dry, sensitive, and mature skin. Both products on this page contain fragrance.

Which is more affordable, Sesderma or ISDIN Isdinceutics?

The page facts do not mention the prices of Sesderma and ISDIN Isdinceutics, so it is not possible to compare which brand is more affordable.

Which causes fewer breakouts, Sesderma or ISDIN Isdinceutics?

For acne-prone skin, Sesderma has a High Lovi fit with its Azelac RU Serum, while ISDIN Isdinceutics has an Average fit with K-Ox Eyes.

When were Sesderma and ISDIN Isdinceutics founded and in which country?

Sesderma was founded in 1989 in Spain, while ISDIN Isdinceutics was founded in 1975 in Spain.

Which company owns Sesderma and who is the parent company of ISDIN Isdinceutics?

Sesderma is owned by Grupo Sesderma, and ISDIN Isdinceutics is owned by Puig.

Do the products from Sesderma and ISDIN Isdinceutics listed on this page contain fragrance?

Yes, both the products on this page from Sesderma and ISDIN Isdinceutics contain fragrance. Specifically, the Azelac RU Serum and K-Ox Eyes both list fragrance.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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