# Neutrogena vs Simple

Page: https://lovi.care/skincare/ca/compare/neutrogena-vs-simple

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Neutrogena and Simple are two renowned skincare brands offering reliable moisturizers, sunscreens, cleansers, and toners formulated with nourishing ingredients like [glycerin](https://lovi.care/skincare/ca/ingredients/glycerin), [hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid), and [niacinamide](https://lovi.care/skincare/ca/ingredients/niacinamide). The American line, founded in 1930, uses glycerin, hyaluronic acid, and [dimethicone](https://lovi.care/skincare/ca/ingredients/dimethicone) to suit mature skin and combination skin best. Conversely, the British line, founded in 1960, features niacinamide and glycerin to suit oily skin and mature skin best. While both brands support skin health through enhanced hydration and barrier function, they differ in their specific formulations and targeted regional origins.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

[investor.kimberly-clark.com](https://www.investor.kimberly-clark.com/news-releases/news-release-details/kimberly-clark-completes-acquisition-kenvue-creating-preeminent) [en.wikipedia.org](https://en.wikipedia.org/wiki/Neutrogena) [investors.kenvue.com](https://investors.kenvue.com/financial-news/news-details/2025/Kimberly-Clark-to-Acquire-Kenvue-Creating-a-32-Billion-Global-Health-and-Wellness-Leader/default.aspx)

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Simple_Skincare) [sec.gov](https://www.sec.gov/Archives/edgar/data/1368457/000119312511134453/dex991.htm) [prnewswire.com](https://www.prnewswire.com/news-releases/alberto-culver-announces-that-unilever-has-received-approval-from-the-us-department-of-justice-to-complete-the-acquisition-of-the-company-121400884.html) [simple.co.uk](https://www.simple.co.uk/philosophy.html)

This page compares some of the most popular Neutrogena and Simple products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg242120325a).

### Popular Neutrogena vs Simple products

#### Neutrogena

- [Hydro Boost Water Gel](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [CA$18.98 at Amazon](https://www.amazon.ca/dp/B0CNBG4G4F?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Ultra Sheer Dry-Touch Sunscreen](https://lovi.care/skincare/ca/p/neutrogena/ultra-sheer-dry-touch-sunscreen/for/combination-skin) — Superior fit — [CA$17.97 at Amazon](https://www.amazon.ca/dp/B0GHPV9VF5?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [HYDRO BOOST WATER CREAM](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-water-cream/for/dry-skin) — Superior fit
- [Ultra Gentle Daily Cleanser](https://lovi.care/skincare/ca/p/neutrogena/ultra-gentle-daily-cleanser/for/mature-skin) — Superior fit — [CA$10.97 at Amazon](https://www.amazon.ca/dp/B0D5BT5CW1?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Rapid Wrinkle Repair Regenerating Cream](https://lovi.care/skincare/ca/p/neutrogena/rapid-wrinkle-repair-regenerating-cream/for/mature-skin) — High fit — [CA$30.59 at Amazon](https://www.amazon.ca/dp/B07998PL5R?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/ca/p/neutrogena/oil-free-eye-makeup-remover/for/dark-spots) — Superior fit — [CA$15.57 at Amazon](https://www.amazon.ca/dp/B081DHMB3T?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Retinol Regenerating Cream](https://lovi.care/skincare/ca/p/neutrogena/retinol-regenerating-cream/for/mature-skin) — Average fit
- [COLLAGEN BANK Moisturizer](https://lovi.care/skincare/ca/p/neutrogena/collagen-bank-moisturizer/for/dry-skin) — Average fit — [CA$25.88 at Amazon](https://www.amazon.ca/dp/B0F7G68ZKK?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)

#### Simple

- [Micellar Water](https://lovi.care/skincare/ca/p/simple/micellar-water/for/mature-skin) — Average fit — [CA$11.99 at Amazon](https://www.amazon.ca/dp/B0GQQSFPG9?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Micellar Cleansing Water](https://lovi.care/skincare/ca/p/simple/micellar-cleansing-water/for/sensitive-skin) — High fit — [CA$11.99 at Amazon](https://www.amazon.ca/dp/B0GQQSFPG9?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Hydrating Light Moisturiser](https://lovi.care/skincare/ca/p/simple/hydrating-light-moisturiser/for/dry-skin) — Average fit — [CA$15.88 at Amazon](https://www.amazon.ca/dp/B000LQX6XG?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Refreshing Facial Wash](https://lovi.care/skincare/ca/p/simple/refreshing-facial-wash/for/acne-prone-skin) — Average fit — [CA$12.79 at Amazon](https://www.amazon.ca/dp/B000LQUA6M?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Replenishing Rich Moisturiser](https://lovi.care/skincare/ca/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [CA$13.40 at Amazon](https://www.amazon.ca/dp/B000LNHB6M?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Water Boost Hydrating Gel Cream](https://lovi.care/skincare/ca/p/simple/water-boost-hydrating-gel-cream/for/dry-skin) — Average fit
- [Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/ca/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — [CA$18.72 at Amazon](https://www.amazon.ca/dp/B076V2D94Y?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)

## People Say

Neutrogena

Simple

- Acne-Safe and Gentle Formula Mostly Mentioned Mostly Mentioned “Does not cause any form of irritation on the skin which I love. — Simple Micellar Cleansing Water” “The only cleanser that doesn't turn my face red. — Simple Micellar Water” “no artificial perfume — Simple Hydrating Light Moisturiser” “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser”
- Deep and Intense Hydration Mostly Mentioned Mostly Mentioned “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM” “Quenches dry skin instantly — Neutrogena Hydro Boost Hydrating Hydrogel Mask” “banished dryness within days — Simple Replenishing Rich Moisturiser” “Instantly boosts skin's hydration... face doesn't feel dry and tight. — Simple Micellar Cleansing Water”
- Lightweight and Non-Greasy Texture Mostly Mentioned Often Mentioned “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel” “absorbs instantly — Neutrogena COLLAGEN BANK Moisturizer” “Absorbs into skin without residue. — Neutrogena Hydro Boost Hyaluronic Acid Serum” “sinks in instantly — Simple Water Boost Hydrating Gel Cream”
- Makeup Compatibility and Base Sometimes Noted Sometimes Noted “Foundation glides right over it — Neutrogena Hydro Boost Water Gel” “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream” “makeup lays well — Simple Hydrating Light Moisturiser” “works well under foundation — Simple Replenishing Rich Moisturiser”
- Affordable Price and Value Rarely Noted Often Mentioned “great value for money — Simple Kind to Skin Soothing Facial Toner” “super affordable — Simple Hydrating Light Moisturiser” “Can't beat the price for the quality. — Simple Micellar Water” “great price point — Neutrogena Oil-Free Eye Makeup Remover”
- Fast Absorption Sometimes Noted Rarely Noted “Absorbs quickly — Neutrogena Rapid Wrinkle Repair Regenerating Cream” “Absorbs really well into my skin without leaving a greasy residue behind. — Neutrogena Retinol Regenerating Cream” “Applies easily and quickly absorbs. — Neutrogena Hydro Boost Hyaluronic Acid Serum” “absorbs really well — Simple Replenishing Rich Moisturiser”
- Insufficient Hydration or Dryness Sometimes Noted Often Mentioned “Not moisturizing enough for winter months — Neutrogena Hydro Boost Water Gel” “Not rich enough for very dry mature skin — Neutrogena Hydro Boost Eye Gel-Cream” “not rich enough — Neutrogena COLLAGEN BANK Moisturizer” “not moisturizing enough — Simple Hydrating Light Moisturiser”
- Packaging and Design Issues Often Mentioned Rarely Noted “Worried about the snap top bottle leaking when travelling. — Simple Micellar Cleansing Water” “The cap broke off immediately. — Simple Micellar Water” “hard to get last bit out — Simple Replenishing Rich Moisturiser” “Formula change ruined it — Neutrogena HYDRO BOOST WATER CREAM”
- Poor Makeup Removal and Waterproof Issues Rarely Noted Often Mentioned “doesn't remove mascara — Neutrogena Ultra Gentle Daily Cleanser” “Did not remove my mascara very well at all. — Simple Micellar Cleansing Water”

### Neutrogena vs Simple routines for dry skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/ca/p/simple/refreshing-facial-wash/for/dry-skin) — Low fit — [CA$12.79 at Amazon](https://www.amazon.ca/dp/B000LQUA6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/ca/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [CA$27.99 at Amazon](https://www.amazon.ca/dp/B07B65NJLV?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/ca/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [CA$13.40 at Amazon](https://www.amazon.ca/dp/B000LNHB6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/ca/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [CA$38.00 at Amazon](https://www.amazon.ca/dp/B091T7JKQJ?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/ca/p/simple/micellar-cleansing-water/for/dry-skin) — High fit — [CA$11.99 at Amazon](https://www.amazon.ca/dp/B0GQQSFPG9?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [SKIN1004 Madagascar Centella Poremizing Fresh Ampoule](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-poremizing-fresh-ampoule/for/dry-skin) — Superior fit — [CA$22.09 at Amazon](https://www.amazon.ca/dp/B0B1JRGGLF?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/ca/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [CA$29.99 at Amazon](https://www.amazon.ca/dp/B09XWPL5VN?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-water-gel/for/dry-skin) — Average fit — [CA$18.98 at Amazon](https://www.amazon.ca/dp/B0CNBG4G4F?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/ca/p/neutrogena/alcohol-free-toner/for/dry-skin) — High fit — [CA$9.97 at Amazon](https://www.amazon.ca/dp/B0CCYYMCZ9?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydro Boost Hyaluronic Acid Serum](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-hyaluronic-acid-serum/for/dry-skin) — Superior fit — [CA$18.98 at Amazon](https://www.amazon.ca/dp/B08PR4R8NT?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Clear Face Liquid Lotion Sunscreen](https://lovi.care/skincare/ca/p/neutrogena/clear-face-liquid-lotion-sunscreen/for/dry-skin) — Average fit — [CA$17.97 at Amazon](https://www.amazon.ca/dp/B08QX7JTZL?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [HYDRO BOOST WATER CREAM](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-water-cream/for/dry-skin) — Superior fit — Evening · Once a week
- Serum or Treatment: [Stubborn Marks PM Treatment](https://lovi.care/skincare/ca/p/neutrogena/stubborn-marks-pm-treatment/for/dry-skin) — Low fit — [CA$29.47 at Amazon](https://www.amazon.ca/dp/B09MKVZS5Y?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Hydro Boost Hydrating Hydrogel Mask](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-hydrating-hydrogel-mask/for/dry-skin) — High fit — [CA$5.79 at Shoppers Drug Mart](https://www.shoppersdrugmart.ca/neutrogena-hydro-boost-hydrating-hydrogel-mask/p/NY48?variantCode=062600246103) — Once a week

[Buy Simple routine · CA$156.25 · 83% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B07B65NJLV&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B091T7JKQJ&Quantity.4=1&ASIN.5=B0GQQSFPG9&Quantity.5=1&ASIN.6=B0B1JRGGLF&Quantity.6=1&ASIN.7=B09XWPL5VN&Quantity.7=1&AssociateTag=lovi-care-web-routine0a-20) [Buy Neutrogena routine · CA$95.37 · 75% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B0CNBG4G4F&Quantity.1=1&ASIN.2=B0CCYYMCZ9&Quantity.2=1&ASIN.3=B08PR4R8NT&Quantity.3=1&ASIN.4=B08QX7JTZL&Quantity.4=1&ASIN.5=B09MKVZS5Y&Quantity.5=1&AssociateTag=lovi-care-web-routine0a-20) [See multi-brand routine · 99% fit](https://lovi.care/skincare/ca/skin/dry-skin)

### Neutrogena vs Simple routines for oily skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/ca/p/simple/refreshing-facial-wash/for/oily-skin) — Average fit — [CA$12.79 at Amazon](https://www.amazon.ca/dp/B000LQUA6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — [CA$37.60 at Amazon](https://www.amazon.ca/dp/B0CJMZB63M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/ca/p/simple/replenishing-rich-moisturiser/for/oily-skin) — Average fit — [CA$13.40 at Amazon](https://www.amazon.ca/dp/B000LNHB6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60](https://lovi.care/skincare/ca/p/la-roche-posay/anthelios-clear-skin-dry-touch-sunscreen-spf-60/for/oily-skin) — Superior fit — [CA$35.95 at Amazon](https://www.amazon.ca/dp/B08CHZPRRB?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/ca/p/simple/micellar-cleansing-water/for/oily-skin) — High fit — [CA$11.99 at Amazon](https://www.amazon.ca/dp/B0GQQSFPG9?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/ca/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [CA$28.90 at Amazon](https://www.amazon.ca/dp/B09SN5B88W?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [The Ordinary Niacinamide 10% + Zinc 1%](https://lovi.care/skincare/ca/p/the-ordinary/niacinamide-10-zinc-1/for/oily-skin) — Superior fit — [CA$6.60 at Amazon](https://www.amazon.ca/dp/B01MDTVZTZ?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Tatcha The Clarifying Clay Mask](https://lovi.care/skincare/ca/p/tatcha/the-clarifying-clay-mask/for/oily-skin) — Superior fit — [CA$95.00 at Amazon](https://www.amazon.ca/dp/B09VCP4J1N?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-water-gel/for/oily-skin) — Caution fit — [CA$18.98 at Amazon](https://www.amazon.ca/dp/B0CNBG4G4F?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/ca/p/neutrogena/alcohol-free-toner/for/oily-skin) — Average fit — [CA$9.97 at Amazon](https://www.amazon.ca/dp/B0CCYYMCZ9?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydro Boost+ Niacinamide Serum](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-skin) — High fit — [CA$23.97 at Amazon](https://www.amazon.ca/dp/B0BQ43Y8VG?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Clear Face Liquid Lotion Sunscreen](https://lovi.care/skincare/ca/p/neutrogena/clear-face-liquid-lotion-sunscreen/for/oily-skin) — Superior fit — [CA$17.97 at Amazon](https://www.amazon.ca/dp/B08QX7JTZL?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/ca/p/neutrogena/oil-free-eye-makeup-remover/for/oily-skin) — Average fit — [CA$15.57 at Amazon](https://www.amazon.ca/dp/B081DHMB3T?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/ca/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [CA$28.90 at Amazon](https://www.amazon.ca/dp/B09SN5B88W?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Stubborn Marks PM Treatment](https://lovi.care/skincare/ca/p/neutrogena/stubborn-marks-pm-treatment/for/oily-skin) — High fit — [CA$29.47 at Amazon](https://www.amazon.ca/dp/B09MKVZS5Y?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Tatcha The Clarifying Clay Mask](https://lovi.care/skincare/ca/p/tatcha/the-clarifying-clay-mask/for/oily-skin) — Superior fit — [CA$95.00 at Amazon](https://www.amazon.ca/dp/B09VCP4J1N?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Simple routine · CA$271.73 · 87% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B0CJMZB63M&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B08CHZPRRB&Quantity.4=1&ASIN.5=B0GQQSFPG9&Quantity.5=1&ASIN.6=B09SN5B88W&Quantity.6=1&ASIN.7=B01MDTVZTZ&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09VCP4J1N&Quantity.9=1&AssociateTag=lovi-care-web-routine0a-20) [Buy Neutrogena routine · CA$269.33 · 77% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B0CNBG4G4F&Quantity.1=1&ASIN.2=B0CCYYMCZ9&Quantity.2=1&ASIN.3=B0BQ43Y8VG&Quantity.3=1&ASIN.4=B08QX7JTZL&Quantity.4=1&ASIN.5=B081DHMB3T&Quantity.5=1&ASIN.6=B09SN5B88W&Quantity.6=1&ASIN.7=B09MKVZS5Y&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09VCP4J1N&Quantity.9=1&AssociateTag=lovi-care-web-routine0a-20) [See multi-brand routine · 96% fit](https://lovi.care/skincare/ca/skin/oily-skin)

### Neutrogena vs Simple routines for combination skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/ca/p/simple/refreshing-facial-wash/for/combination-skin) — Average fit — [CA$12.79 at Amazon](https://www.amazon.ca/dp/B000LQUA6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [CA$37.60 at Amazon](https://www.amazon.ca/dp/B0CJMZB63M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/ca/p/simple/replenishing-rich-moisturiser/for/combination-skin) — Average fit — [CA$13.40 at Amazon](https://www.amazon.ca/dp/B000LNHB6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/ca/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [CA$20.96 at Amazon](https://www.amazon.ca/dp/B083GGPQ8C?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/ca/p/simple/micellar-cleansing-water/for/combination-skin) — Average fit — [CA$11.99 at Amazon](https://www.amazon.ca/dp/B0GQQSFPG9?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/ca/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [CA$31.99 at Amazon](https://www.amazon.ca/dp/B0CVRCR6VF?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [The Ordinary Niacinamide 10% + Zinc 1%](https://lovi.care/skincare/ca/p/the-ordinary/niacinamide-10-zinc-1/for/combination-skin) — Superior fit — [CA$6.60 at Amazon](https://www.amazon.ca/dp/B01MDTVZTZ?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Origins Original Skin Retexturizing Mask with Rose Clay](https://lovi.care/skincare/ca/p/origins/original-skin-retexturizing-mask-with-rose-clay/for/combination-skin) — Superior fit — [CA$50.00 at Amazon](https://www.amazon.ca/dp/B0DV8YNCC5?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-water-gel/for/combination-skin) — Low fit — [CA$18.98 at Amazon](https://www.amazon.ca/dp/B0CNBG4G4F?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/ca/p/neutrogena/alcohol-free-toner/for/combination-skin) — Average fit — [CA$9.97 at Amazon](https://www.amazon.ca/dp/B0CCYYMCZ9?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydro Boost Hyaluronic Acid Serum](https://lovi.care/skincare/ca/p/neutrogena/hydro-boost-hyaluronic-acid-serum/for/combination-skin) — High fit — [CA$18.98 at Amazon](https://www.amazon.ca/dp/B08PR4R8NT?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Ultra Sheer Dry-Touch Sunscreen](https://lovi.care/skincare/ca/p/neutrogena/ultra-sheer-dry-touch-sunscreen/for/combination-skin) — Superior fit — [CA$17.97 at Amazon](https://www.amazon.ca/dp/B0GHPV9VF5?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/ca/p/neutrogena/oil-free-eye-makeup-remover/for/combination-skin) — High fit — [CA$15.57 at Amazon](https://www.amazon.ca/dp/B081DHMB3T?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/ca/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [CA$31.99 at Amazon](https://www.amazon.ca/dp/B0CVRCR6VF?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Stubborn Marks PM Treatment](https://lovi.care/skincare/ca/p/neutrogena/stubborn-marks-pm-treatment/for/combination-skin) — High fit — [CA$29.47 at Amazon](https://www.amazon.ca/dp/B09MKVZS5Y?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Origins Original Skin Retexturizing Mask with Rose Clay](https://lovi.care/skincare/ca/p/origins/original-skin-retexturizing-mask-with-rose-clay/for/combination-skin) — Superior fit — [CA$50.00 at Amazon](https://www.amazon.ca/dp/B0DV8YNCC5?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Simple routine · CA$214.83 · 86% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B0CJMZB63M&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B083GGPQ8C&Quantity.4=1&ASIN.5=B0GQQSFPG9&Quantity.5=1&ASIN.6=B0CVRCR6VF&Quantity.6=1&ASIN.7=B01MDTVZTZ&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B0DV8YNCC5&Quantity.9=1&AssociateTag=lovi-care-web-routine0a-20) [Buy Neutrogena routine · CA$222.43 · 81% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B0CNBG4G4F&Quantity.1=1&ASIN.2=B0CCYYMCZ9&Quantity.2=1&ASIN.3=B08PR4R8NT&Quantity.3=1&ASIN.4=B0GHPV9VF5&Quantity.4=1&ASIN.5=B081DHMB3T&Quantity.5=1&ASIN.6=B0CVRCR6VF&Quantity.6=1&ASIN.7=B09MKVZS5Y&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B0DV8YNCC5&Quantity.9=1&AssociateTag=lovi-care-web-routine0a-20) [See multi-brand routine · 96% fit](https://lovi.care/skincare/ca/skin/combination-skin)

## Questions and answers

### Neutrogena or Simple: which is better?

Neutrogena and Simple both provide high routine fit levels across most skin types, while Simple achieves a High fit for sensitive and dry sensitive skin compared to Neutrogena's Average fit. The products on this page from Simple feature fragrance-free formulations, whereas Neutrogena offers specialized anti-aging ingredients like [retinol](https://lovi.care/skincare/ca/ingredients/retinol).

### What is the difference between Neutrogena and Simple?

Neutrogena and Simple both offer products on this page that fit dry, oily, combination, acne-prone, mature skin, and skin with dark spots at a High level. However, Simple achieves a High fit level for sensitive and dry sensitive skin, whereas Neutrogena reaches an Average fit level for those skin types.

### Neutrogena or Simple for dry skin?

Both Neutrogena and Simple achieve a High routine fit level for dry skin based on the products on this page. [Hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid) helps provide deep hydration to the skin.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Neutrogena or Simple: which cleanser is better?

Neutrogena offers a wider variety of cleansers on this page that achieve High to Superior fit levels across most skin types, while Simple provides more value-friendly options. Reviewers note that Simple tends to be better for an acne-safe and gentle formula.

### Which is more affordable, Neutrogena or Simple?

Simple is more affordable than Neutrogena, offering better value-friendly moisturizers and products on this page. Reviewers note that Simple provides a more budget-friendly approach, while Neutrogena often receives packaging and value concerns.

### Between Neutrogena and Simple, which brand offers better fragrance-free options?

Simple offers better fragrance-free options because every product on its page lists no fragrance, whereas Neutrogena includes fragrance in a few of its items.

### Neutrogena or Simple: which brand performs better for mature skin and skin with dark spots?

Both Neutrogena and Simple achieve a High routine fit for mature skin and skin with dark spots, meaning either brand helps address these concerns effectively.

### Which brand has more lightweight and non-greasy texture according to reviewer feedback?

Neutrogena does better than Simple for a lightweight and non-greasy texture.

### Neutrogena or Simple for oily skin?

Both Neutrogena and Simple achieve a High routine fit for oily skin on this page. Neutrogena is noted for its lightweight and non-greasy textures, while Simple offers value-friendly formulations.

### Neutrogena or Simple: which moisturizer is better?

Neutrogena and Simple both offer moisturizers with a High routine fit for dry, oily, combination, acne-prone, mature, and dark spot skin types, while Simple achieves a High fit for sensitive and dry sensitive skin compared to Neutrogena's Average fit. Neutrogena features deeply hydrating and lightweight moisturizers with key ingredients like hyaluronic acid and retinol, whereas Simple is noted for value-friendly and gentle formulas.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/)

### Neutrogena or Simple for sensitive skin?

Simple is the better choice for sensitive skin because its products on this page achieve a High Lovi fit level compared to Neutrogena's Average fit. Additionally, Simple features fragrance-free formulas across all products on this page, whereas some Neutrogena options contain added scent.

### Neutrogena or Simple for acne-prone skin?

Both Neutrogena and Simple achieve a High routine fit for acne-prone skin with the products on this page. Simple does better for acne-safe and gentle formulas, while Neutrogena offers superior fast absorption and lightweight textures.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Sodium hyaluronate · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate](https://pubmed.ncbi.nlm.nih.gov/11766131/) Benzyl alcohol · International Journal of Toxicology, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf extract · Iranian Journal of Medical Sciences, 2019
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Final report on the safety assessment of BHT(1)](https://pubmed.ncbi.nlm.nih.gov/12396675/) Bht · International Journal of Toxicology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol, Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice, Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Sacha Inchi Oil (Plukenetia volubilis L.), effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro](https://pubmed.ncbi.nlm.nih.gov/26087228/) Plukenetia volubilis seed oil · Journal of Ethnopharmacology, 2015
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic Dermatology, 2007
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine, Neoglucosamine · The British Journal of Dermatology, 2010
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Phytosphingosine enhances moisture level in human skin barrier through stimulation of the filaggrin biosynthesis and degradation leading to NMF formation](https://pubmed.ncbi.nlm.nih.gov/28936777/) Hydration complex · Archives of Dermatological Research, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid, Microclear technology · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)](https://pubmed.ncbi.nlm.nih.gov/19112586/) Chrysanthemum parthenium flower leaf stem juice · Inflammopharmacology, 2009
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid, Microclear technology · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol](https://pubmed.ncbi.nlm.nih.gov/27391637/) Hexylresorcinol · Journal of Drugs in Dermatology, 2016
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Preparation and evaluation of benzalkonium chloride hand sanitizer as a potential alternative for alcohol-based hand gels](https://pubmed.ncbi.nlm.nih.gov/34408542/) Benzalkonium chloride · Saudi Pharmaceutical Journal, 2021
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Hydration complex · Molecules, 2021
- [Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide](https://pubmed.ncbi.nlm.nih.gov/34958693/) Hexylresorcinol · International Journal of Cosmetic Science, 2022
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid, Microclear technology · Journal of Drugs in Dermatology, 2023
- [Efficacy and tolerability of the investigational topical cream SD-101 (6% allantoin) in patients with epidermolysis bullosa: a phase 3, randomized, double-blind, vehicle-controlled trial (ESSENCE study)](https://pubmed.ncbi.nlm.nih.gov/32576219/) Allantoin · Orphanet Journal of Rare Diseases, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Grapefruit extract · Frontiers in Chemistry, 2024
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Parthenolide-depleted Feverfew (Tanacetum parthenium) protects skin from UV irradiation and external aggression](https://pubmed.ncbi.nlm.nih.gov/18071724/) Chrysanthemum parthenium flower leaf stem juice · Archives of Dermatological Research, 2008
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/19622017/) Oxybenzone, Oxybenzone-free formula · Journal of Microencapsulation, 2010
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) Acetyl glucosamine, Neoglucosamine · Advanced Pharmaceutical Bulletin, 2016
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis seed oil · Lipids, 2020
- [Axillary hyperhidrosis. Local treatment with aluminium-chloride hexahydrate 25% in absolute ethanol with and without supplementary treatment with triethanolamine](https://pubmed.ncbi.nlm.nih.gov/2449022/) Triethanolamine · Acta Dermato-venereologica, 1988
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Oxybenzone-free formula · International Journal of Pharmaceutics, 2019
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Rates of allergic sensitization and irritation to oxybenzone-containing sunscreen products: a quantitative meta-analysis of 64 exaggerated use studies](https://pubmed.ncbi.nlm.nih.gov/18717962/) Helioplex technology, Helioplex · Photodermatology, Photoimmunology & Photomedicine, 2008
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Avobenzone · European Journal of Pharmaceutical Sciences, 2023
- [A new formula for a mild body cleanser: sodium laureth sulphate supplemented with sodium laureth carboxylate and lauryl glucoside](https://pubmed.ncbi.nlm.nih.gov/24617572/) Lauryl glucoside · International Journal of Cosmetic Science, 2014
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance](https://pubmed.ncbi.nlm.nih.gov/36502500/) Hexylresorcinol · Archives of Dermatological Research, 2023
- [Instrumental, clinical and subjective evaluation of the efficacy of a cosmetic treatment for home use](https://pubmed.ncbi.nlm.nih.gov/30040516/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic and Laser Therapy, 2019
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octocrylene · Archives of Dermatological Research, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2022
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate, Octisalate, Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
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- [Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream](https://pubmed.ncbi.nlm.nih.gov/38443132/) Hydration complex · Journal of Drugs in Dermatology, 2024
- [Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration](https://pubmed.ncbi.nlm.nih.gov/41129958/) Sodium pca · Biomaterials Advances, 2026
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- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Saccharide isomerate · Lasers in Medical Science, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
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- [Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population](https://pubmed.ncbi.nlm.nih.gov/35279940/) Saccharide isomerate · Journal of Cosmetic Dermatology, 2023

## The brands

- American skincare: [Neutrogena](https://lovi.care/skincare/ca/brands/neutrogena)
- British skincare: [Simple](https://lovi.care/skincare/ca/brands/simple)

## More comparisons

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- [SKIN1004 vs Simple](https://lovi.care/skincare/ca/compare/skin1004-vs-simple)
- [Anua vs Neutrogena](https://lovi.care/skincare/ca/compare/anua-vs-neutrogena)
- [Anua vs Simple](https://lovi.care/skincare/ca/compare/anua-vs-simple)
- [Medicube vs Neutrogena](https://lovi.care/skincare/ca/compare/medicube-vs-neutrogena)
- [Medicube vs Simple](https://lovi.care/skincare/ca/compare/medicube-vs-simple)
- [The Ordinary vs Neutrogena](https://lovi.care/skincare/ca/compare/the-ordinary-vs-neutrogena)
- [The Ordinary vs Simple](https://lovi.care/skincare/ca/compare/the-ordinary-vs-simple)
- [Beauty of Joseon vs Neutrogena](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-neutrogena)
- [Beauty of Joseon vs Simple](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-simple)
- [COSRX vs Neutrogena](https://lovi.care/skincare/ca/compare/cosrx-vs-neutrogena)
- [COSRX vs Simple](https://lovi.care/skincare/ca/compare/cosrx-vs-simple)
- [CeraVe vs Neutrogena](https://lovi.care/skincare/ca/compare/cerave-vs-neutrogena)
- [CeraVe vs Simple](https://lovi.care/skincare/ca/compare/cerave-vs-simple)
- [La Roche-Posay vs Neutrogena](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-neutrogena)
- [La Roche-Posay vs Simple](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-simple)
- [Dr. Althea vs Neutrogena](https://lovi.care/skincare/ca/compare/dr-althea-vs-neutrogena)
- [Dr. Althea vs Simple](https://lovi.care/skincare/ca/compare/dr-althea-vs-simple)
- [Some By Mi vs Neutrogena](https://lovi.care/skincare/ca/compare/some-by-mi-vs-neutrogena)
- [Some By Mi vs Simple](https://lovi.care/skincare/ca/compare/some-by-mi-vs-simple)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/neutrogena-vs-simple
- United Kingdom: https://lovi.care/skincare/uk/compare/neutrogena-vs-simple
- Ireland: https://lovi.care/skincare/ie/compare/neutrogena-vs-simple
- Germany: https://lovi.care/skincare/de/compare/neutrogena-vs-simple
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- Italy: https://lovi.care/skincare/it/compare/neutrogena-vs-simple
- Netherlands: https://lovi.care/skincare/nl/compare/neutrogena-vs-simple
- Spain: https://lovi.care/skincare/es/compare/neutrogena-vs-simple
- Canada: https://lovi.care/skincare/ca/compare/neutrogena-vs-simple (this page)
- Australia: https://lovi.care/skincare/au/compare/neutrogena-vs-simple
- Singapore: https://lovi.care/skincare/sg/compare/neutrogena-vs-simple
- Saudi Arabia: https://lovi.care/skincare/sa/compare/neutrogena-vs-simple
- United Arab Emirates: https://lovi.care/skincare/ae/compare/neutrogena-vs-simple