# Mesoestetic vs MAËLYS

Page: https://lovi.care/skincare/ca/compare/mesoestetic-vs-maelys

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Mesoestetic and MAËLYS are specialized skincare lines known for their targeted [serums](https://lovi.care/skincare/ca/ingredients/serum) and advanced formulas that elevate daily routines. The Spanish brand founded in 1984 suits mature, sensitive, and uneven skin best with its gentle yet rigorous composition, featuring the Cosmelan 2 for acne-prone skin, while the other brand suits all skin types best, featuring the TOO-FINE for acne-prone skin and the RE-LURE Tight & Tone Body Serum for skin with dark spots. Both deliver thoughtful care and balanced nourishment through these specialized solutions to support long-term skin health.

Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L..

[mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk)

This page compares some of the most popular Mesoestetic and MAËLYS products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg8a3c5bdd1a).

### Popular Mesoestetic vs MAËLYS products

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/ca/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

#### MAËLYS

- [TOO-FINE](https://lovi.care/skincare/ca/p/maelys/too-fine/for/sensitive-skin) — Low fit
- [RE-LURE Tight & Tone Body Serum](https://lovi.care/skincare/ca/p/maelys/re-lure-tight-and-tone-body-serum/for/dry-sensitive-skin) — Average fit

### Mesoestetic vs MAËLYS [serums](https://lovi.care/skincare/ca/ingredients/serum) and treatments

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/ca/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

#### MAËLYS

- [TOO-FINE](https://lovi.care/skincare/ca/p/maelys/too-fine/for/sensitive-skin) — Low fit

## Questions and answers

### Mesoestetic or MAËLYS: which is better?

Neither brand stands out as better, because the products on this page achieve only Average or lower Lovi fit levels across all skin types. Every product from Mesoestetic lists no fragrance, whereas half of MAËLYS's products contain fragrance.

### What is the difference between Mesoestetic and MAËLYS?

Mesoestetic features products on this page that list no fragrance, whereas MAËLYS includes a scented formula in its range. Lovi gives Mesoestetic an Average fit across most skin types, while MAËLYS ranges from Low to Caution depending on the product and skin type.

### Which is more affordable, Mesoestetic or MAËLYS?

Neither Mesoestetic nor MAËLYS shares pricing details for the products on this page.

### Which causes fewer breakouts, Mesoestetic or MAËLYS?

Mesoestetic is more likely to cause fewer breakouts because the products on this page have an average fit for acne-prone skin, whereas MAËLYS products on this page have a low fit or caution for that skin type.

### When were Mesoestetic and MAËLYS founded and who owns them?

Mesoestetic was founded in 1984 in Spain and is owned by Mesoestetic Pharma Group, S.L., while MAËLYS was founded in 2017 and is owned by Barinboim Group.

### Do Mesoestetic and MAËLYS products contain fragrance?

Every product from Mesoestetic on this page lists no fragrance in its ingredients, whereas one of the two MAËLYS products on this page contains fragrance.

### How does the Lovi fit level of Cosmelan 2 compare to MAËLYS products for dry skin?

For dry skin, Mesoestetic's Cosmelan 2 has a Low Lovi fit level, whereas MAËLYS products range from Low to Average.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome](https://pubmed.ncbi.nlm.nih.gov/33526970/) Lactobacillus · International Journal of Medical Sciences, 2021
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021
- [Efficacy of probiotic-derived lotion from Lactobacillus paracasei MSMC 39-1 in mild to moderate acne vulgaris, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/35384257/) Lactobacillus · Journal of Cosmetic Dermatology, 2022
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Evaluation of a retinol containing topical treatment to improve signs of neck aging](https://pubmed.ncbi.nlm.nih.gov/37461826/) Glaucine · Journal of Cosmetic Dermatology, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Clinical and histologic findings after use of a novel combined retinol, tripeptide, and glaucine containing cream in the treatment of photo-aged skin](https://pubmed.ncbi.nlm.nih.gov/37584260/) Glaucine · Journal of Cosmetic Dermatology, 2023

## The brands

- Spanish skincare: [Mesoestetic](https://lovi.care/skincare/ca/brands/mesoestetic)
- Skincare: [MAËLYS](https://lovi.care/skincare/ca/brands/maelys)

## More comparisons

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- [Anua vs MAËLYS](https://lovi.care/skincare/ca/compare/anua-vs-maelys)
- [Medicube vs Mesoestetic](https://lovi.care/skincare/ca/compare/medicube-vs-mesoestetic)
- [Medicube vs MAËLYS](https://lovi.care/skincare/ca/compare/medicube-vs-maelys)
- [The Ordinary vs Mesoestetic](https://lovi.care/skincare/ca/compare/the-ordinary-vs-mesoestetic)
- [The Ordinary vs MAËLYS](https://lovi.care/skincare/ca/compare/the-ordinary-vs-maelys)
- [Beauty of Joseon vs Mesoestetic](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-mesoestetic)
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- [COSRX vs Mesoestetic](https://lovi.care/skincare/ca/compare/cosrx-vs-mesoestetic)
- [COSRX vs MAËLYS](https://lovi.care/skincare/ca/compare/cosrx-vs-maelys)
- [CeraVe vs Mesoestetic](https://lovi.care/skincare/ca/compare/cerave-vs-mesoestetic)
- [CeraVe vs MAËLYS](https://lovi.care/skincare/ca/compare/cerave-vs-maelys)
- [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-mesoestetic)
- [La Roche-Posay vs MAËLYS](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-maelys)
- [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/ca/compare/dr-althea-vs-mesoestetic)
- [Dr. Althea vs MAËLYS](https://lovi.care/skincare/ca/compare/dr-althea-vs-maelys)
- [Some By Mi vs Mesoestetic](https://lovi.care/skincare/ca/compare/some-by-mi-vs-mesoestetic)
- [Some By Mi vs MAËLYS](https://lovi.care/skincare/ca/compare/some-by-mi-vs-maelys)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- Spain: https://lovi.care/skincare/es/compare/mesoestetic-vs-maelys
- Canada: https://lovi.care/skincare/ca/compare/mesoestetic-vs-maelys (this page)
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