# La Roche-Posay vs Paula's Choice

Page: https://lovi.care/skincare/ca/compare/la-roche-posay-vs-paula-s-choice

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

La Roche-Posay and Paula's Choice are well-regarded skincare brands that offer [serums](https://lovi.care/skincare/ca/ingredients/serum), cleansers, moisturizers, and more. The French brand incorporates [glycerin](https://lovi.care/skincare/ca/ingredients/glycerin), [thermal water](https://lovi.care/skincare/ca/ingredients/thermal-water), and [niacinamide](https://lovi.care/skincare/ca/ingredients/niacinamide) to suit dry skin and skin with dark spots best, whereas the American brand builds its products around [hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid), glycerin, and [vitamin c](https://lovi.care/skincare/ca/ingredients/vitamin-c) for combination skin and oily skin. Both provide thoughtful formulations with key ingredients like glycerin, which significantly increased skin hydration and restored barrier function. Ultimately, the brands differ in their specific ingredient profiles and ideal skin types, offering distinct paths to supportive daily care.

La Roche-Posay is a French skincare brand founded in 1975 and owned by L'Oréal S.A. since 1989.

[laroche-posay.com.au](https://www.laroche-posay.com.au/our-commitments/history.html) [fr.wikipedia.org](https://fr.wikipedia.org/wiki/L%27Or%C3%A9al)

Paula's Choice is an American skincare brand founded in 1995 and owned by Unilever since 2021.

[unilever.com](https://www.unilever.com/news/press-and-media/press-releases/2021/unilever-to-acquire-paulas-choice-skincare/) [tracxn.com](https://tracxn.com/d/companies/paulas-choice/__3NzlGcC2yhs-Z9XjkOCar6Dxe0DJgowfl0PAX9OD5s8)

This page compares some of the most popular La Roche-Posay and Paula's Choice products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgb7736de52d).

### Popular La Roche-Posay vs Paula's Choice products

#### Paula's Choice

- [Skin Perfecting 2% BHA Liquid Exfoliant](https://lovi.care/skincare/ca/p/paula-s-choice/skin-perfecting-2-bha-liquid-exfoliant/for/oily-skin) — Superior fit — [CA$52.00 at Amazon](https://www.amazon.ca/dp/B0CJH3R48Z?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [1% Retinol Treatment](https://lovi.care/skincare/ca/p/paula-s-choice/1-retinol-treatment/for/dark-spots) — Superior fit — [CA$70.50 at Amazon](https://www.amazon.ca/dp/B0CKWP1Z9J?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [10% Azelaic Acid Booster](https://lovi.care/skincare/ca/p/paula-s-choice/10-azelaic-acid-booster/for/acne-prone-skin) — High fit — [CA$58.00 at Amazon](https://www.amazon.ca/dp/B0CLFPDVZ4?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [C15 Super Booster](https://lovi.care/skincare/ca/p/paula-s-choice/c15-super-booster/for/mature-skin) — High fit — [CA$84.00 at Amazon](https://www.amazon.ca/dp/B0H6N4XPLG?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/ca/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — [CA$54.99 at Amazon](https://www.amazon.ca/dp/B0CB3PXRQN?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [10% Niacinamide Booster](https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/dry-sensitive-skin) — Superior fit
- [Weightless Body Treatment 2% BHA](https://lovi.care/skincare/ca/p/paula-s-choice/weightless-body-treatment-2-bha/for/oily-acne-prone-skin) — Average fit — [CA$49.00 at Amazon](https://www.amazon.ca/dp/B0CJMYXHDZ?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [CA$37.60 at Amazon](https://www.amazon.ca/dp/B0CJMZB63M?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)

#### La Roche-Posay

- [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit — [CA$31.00 at Amazon](https://www.amazon.ca/dp/B07942ZQBT?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Cicaplast Baume B5+](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-baume-b5/for/sensitive-skin) — Superior fit — [CA$29.95 at Amazon](https://www.amazon.ca/dp/B0BT6R8ZXC?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Mela B3 Serum](https://lovi.care/skincare/ca/p/la-roche-posay/mela-b3-serum/for/acne-prone-skin) — High fit — [CA$73.00 at Amazon](https://www.amazon.ca/dp/B0CM4B43DZ?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Retinol B3 Serum](https://lovi.care/skincare/ca/p/la-roche-posay/retinol-b3-serum/for/dark-spots) — Average fit — [CA$72.00 at Amazon](https://www.amazon.ca/dp/B07Z9Y4M3C?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/ca/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/acne-prone-skin) — High fit — [CA$31.95 at Amazon](https://www.amazon.ca/dp/B0CYQSGR5P?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Hyalu B5 Serum](https://lovi.care/skincare/ca/p/la-roche-posay/hyalu-b5-serum/for/sensitive-skin) — High fit — [CA$64.00 at Amazon](https://www.amazon.ca/dp/B075VX4QVM?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Lipikar AP+M Triple Repair Moisturizing Cream](https://lovi.care/skincare/ca/p/la-roche-posay/lipikar-ap-m-triple-repair-moisturizing-cream/for/dry-skin) — High fit — [CA$26.95 at Amazon](https://www.amazon.ca/dp/B09V542XVS?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Anthelios](https://lovi.care/skincare/ca/p/la-roche-posay/anthelios/for/dark-spots) — Superior fit — [CA$35.95 at Amazon](https://www.amazon.ca/dp/B08BMV5VDL?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)

## People Say

La Roche-Posay

Paula's Choice

- Fragrance-free and Gentle Formulas Mostly Mentioned Often Mentioned “Great retinol for beginners — La Roche-Posay Retinol B3 Serum” “Only cream that doesn't sting — La Roche-Posay Toleriane Dermallergo Eye Cream” “zero scent — La Roche-Posay Toleriane Double Repair Face Moisturizer” “Finally a vitamin C product I can use — Paula's Choice 25% Vitamin C + Glutathione Clinical Serum”
- Skin Texture Improvement Often Mentioned Mostly Mentioned “skin becomes very smooth — Paula's Choice 1% Retinol Treatment” “bumps be gone — Paula's Choice Weightless Body Treatment 2% BHA” “skin is insanely soft — Paula's Choice Weightless Body Treatment 2% BHA” “Skin feels smoother — La Roche-Posay Retinol B3 Serum”
- Hydration and Moisture Mostly Mentioned Sometimes Noted “absorbs instantly — La Roche-Posay Toleriane Double Repair Face Moisturizer” “skin feels plump — La Roche-Posay Hyalu B5 Serum” “legs stopped flaking — La Roche-Posay Lipikar AP+M Triple Repair Moisturizing Cream” “Provides an internal level of hydration without leaving any heavy finish. — Paula's Choice Skin Balancing Pore-Reducing Toner”
- Acne Clearing and Oil Control Sometimes Noted Mostly Mentioned “cleared my bumps — Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant” “Helped clear my cystic acne — Paula's Choice CLEAR Pore Normalizing Cleanser” “pores look smaller — Paula's Choice 10% Niacinamide Booster” “clears acne blemishes — La Roche-Posay Effaclar Medicated Gel Cleanser”
- Good Texture Sometimes Noted Often Mentioned “absorbs instantly — Paula's Choice C15 Super Booster” “absorbs quickly — Paula's Choice Weightless Body Treatment 2% BHA” “Absorbs like a dream — Paula's Choice 25% Vitamin C + Glutathione Clinical Serum” “lightweight and absorbs quickly — La Roche-Posay Mela B3 Serum”
- Brightening and Fading Dark Spots Sometimes Noted Often Mentioned “visible glow — Paula's Choice C15 Super Booster” “acne scars faded — Paula's Choice 10% Azelaic Acid Booster” “Discoloration almost gone — Paula's Choice 25% Vitamin C + Glutathione Clinical Serum” “skin looks brighter — La Roche-Posay Mela B3 Serum”
- Price vs Size Value Sometimes Noted Mostly Mentioned “expensive for the size — La Roche-Posay Hyalu B5 Serum” “Too expensive for the size — La Roche-Posay Toleriane Dermallergo Eye Cream” “Tube is tiny for the price — La Roche-Posay Cicaplast Gel B5” “surprisingly small bottle — Paula's Choice Skin-Smoothing Retinol Body Treatment”
- Strong Fragrance and Scents Sometimes Noted Often Mentioned “scent is awful — La Roche-Posay Mela B3 Serum” “overwhelming floral smell — La Roche-Posay Hyalu B5 Serum” “smells like grain — Paula's Choice 10% Azelaic Acid Booster” “smells like hot dog water — Paula's Choice C15 Super Booster”
- Packaging Issues and Faulty Pumps Often Mentioned Sometimes Noted “dropper leaks — Paula's Choice C15 Super Booster” “dropper can be unpredictable — Paula's Choice Pro-Collagen Multi-Peptide Booster” “Cap broke immediately — Paula's Choice CLEAR Pore Normalizing Cleanser” “pump stops working — La Roche-Posay Lipikar AP+M Triple Repair Moisturizing Cream”
- Product Texture and Pilling Often Mentioned Rarely Noted “sticky, oily film — Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant” “pills under makeup — Paula's Choice 10% Azelaic Acid Booster” “pills like crazy — La Roche-Posay Toleriane Double Repair Face Moisturizer”

### La Roche-Posay vs Paula's Choice routines for dry skin

#### La Roche-Posay-focused routine

- Cleanser: [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/dry-skin) — Average fit — [CA$31.00 at Amazon](https://www.amazon.ca/dp/B07942ZQBT?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/ca/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [CA$27.99 at Amazon](https://www.amazon.ca/dp/B07B65NJLV?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Pure Vitamin C Cream](https://lovi.care/skincare/ca/p/la-roche-posay/pure-vitamin-c-cream/for/dry-skin) — Superior fit — [CA$59.00 at Amazon](https://www.amazon.ca/dp/B0038COKQ2?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Respectissime Waterproof Eye Makeup Remover](https://lovi.care/skincare/ca/p/la-roche-posay/respectissime-waterproof-eye-makeup-remover/for/dry-skin) — High fit — [CA$24.50 at Amazon](https://www.amazon.ca/dp/B000V3MGFS?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Cicaplast Gel B5](https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/dry-skin) — Superior fit — [CA$26.00 at Amazon](https://www.amazon.ca/dp/B077YNHBSL?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/ca/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [CA$29.99 at Amazon](https://www.amazon.ca/dp/B09XWPL5VN?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

#### Paula's Choice-focused routine

- Cleanser: [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/ca/p/paula-s-choice/clear-pore-normalizing-cleanser/for/dry-skin) — Caution fit — [CA$54.99 at Amazon](https://www.amazon.ca/dp/B0CB3PXRQN?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Skin Recovery Enriched Calming Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-recovery-enriched-calming-toner/for/dry-skin) — Superior fit — [CA$47.00 at Amazon](https://www.amazon.ca/dp/B0CLFQ68RQ?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Replenishing Moisturizer](https://lovi.care/skincare/ca/p/paula-s-choice/replenishing-moisturizer/for/dry-skin) — High fit — [CA$68.00 at Amazon](https://www.amazon.ca/dp/B0DWZP933S?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Youth-Extending Daily Hydrating Fluid SPF 50](https://lovi.care/skincare/ca/p/paula-s-choice/youth-extending-daily-hydrating-fluid-spf-50/for/dry-skin) — High fit — [CA$55.00 at Sephora](https://www.sephora.com/ca/en/product/paulas-choice-resist-youth-extending-daily-hydrating-fluid-spf-50-P511986?skuId=2787026) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ca/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [CA$17.99 at Amazon](https://www.amazon.ca/dp/B084Q16G8D?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Pro-Collagen Multi-Peptide Booster](https://lovi.care/skincare/ca/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/dry-skin) — Superior fit — [CA$84.00 at Amazon](https://www.amazon.ca/dp/B0CLFGX2LQ?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/ca/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [CA$29.99 at Amazon](https://www.amazon.ca/dp/B09XWPL5VN?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy La Roche-Posay routine · CA$198.48 · 91% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B07942ZQBT&Quantity.1=1&ASIN.2=B07B65NJLV&Quantity.2=1&ASIN.3=B0038COKQ2&Quantity.3=1&ASIN.4=B000V3MGFS&Quantity.4=1&ASIN.5=B077YNHBSL&Quantity.5=1&ASIN.6=B09XWPL5VN&Quantity.6=1&AssociateTag=lovi-care-web-routine0a-20) [Buy Paula's Choice routine · CA$301.97 · 84% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B0CB3PXRQN&Quantity.1=1&ASIN.2=B0CLFQ68RQ&Quantity.2=1&ASIN.3=B0DWZP933S&Quantity.3=1&ASIN.4=B084Q16G8D&Quantity.4=1&ASIN.5=B0CLFGX2LQ&Quantity.5=1&ASIN.6=B09XWPL5VN&Quantity.6=1&AssociateTag=lovi-care-web-routine0a-20) [See multi-brand routine · 99% fit](https://lovi.care/skincare/ca/skin/dry-skin)

### La Roche-Posay vs Paula's Choice routines for oily skin

#### Paula's Choice-focused routine

- Cleanser: [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/ca/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-skin) — Superior fit — [CA$54.99 at Amazon](https://www.amazon.ca/dp/B0CB3PXRQN?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Advanced Replenishing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/advanced-replenishing-toner/for/oily-skin) — High fit — [CA$41.00 at Amazon](https://www.amazon.ca/dp/B0DX19HGD4?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [RESIST Intensive Wrinkle-Repair Retinol Serum](https://lovi.care/skincare/ca/p/paula-s-choice/resist-intensive-wrinkle-repair-retinol-serum/for/oily-skin) — Average fit — [CA$102.00 at Sephora](https://www.sephora.com/ca/en/product/longevity-serum-P519786?skuId=2932333) — Morning · Evening · Once a week
- SPF: [Youth-Extending Daily Hydrating Fluid SPF 50](https://lovi.care/skincare/ca/p/paula-s-choice/youth-extending-daily-hydrating-fluid-spf-50/for/oily-skin) — Average fit — [CA$55.00 at Sephora](https://www.sephora.com/ca/en/product/paulas-choice-resist-youth-extending-daily-hydrating-fluid-spf-50-P511986?skuId=2787026) — Morning
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/ca/p/pyunkang-yul/deep-cleansing-oil/for/oily-skin) — Superior fit — [CA$23.99 at Amazon](https://www.amazon.ca/dp/B08QTT1QBX?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/ca/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [CA$28.90 at Amazon](https://www.amazon.ca/dp/B09SN5B88W?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Niacinamide 20% Treatment](https://lovi.care/skincare/ca/p/paula-s-choice/niacinamide-20-treatment/for/oily-skin) — Superior fit — [CA$84.00 at Amazon](https://www.amazon.ca/dp/B0CKWNT299?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Tatcha The Clarifying Clay Mask](https://lovi.care/skincare/ca/p/tatcha/the-clarifying-clay-mask/for/oily-skin) — Superior fit — [CA$95.00 at Amazon](https://www.amazon.ca/dp/B09VCP4J1N?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

#### La Roche-Posay-focused routine

- Cleanser: [MELA B3 Facial Gel Cleanser](https://lovi.care/skincare/ca/p/la-roche-posay/mela-b3-facial-gel-cleanser/for/oily-skin) — High fit — [CA$33.00 at Amazon](https://www.amazon.ca/dp/B0CZ3YFMWQ?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — [CA$37.60 at Amazon](https://www.amazon.ca/dp/B0CJMZB63M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-skin) — High fit — [CA$31.00 at Amazon](https://www.amazon.ca/dp/B07942ZQBT?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Anthelios](https://lovi.care/skincare/ca/p/la-roche-posay/anthelios/for/oily-skin) — Superior fit — [CA$35.95 at Amazon](https://www.amazon.ca/dp/B08BMV5VDL?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Water Ultra](https://lovi.care/skincare/ca/p/la-roche-posay/micellar-water-ultra/for/oily-skin) — Average fit — [CA$27.95 at Amazon](https://www.amazon.ca/dp/B005EZSUS0?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/ca/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [CA$28.90 at Amazon](https://www.amazon.ca/dp/B09SN5B88W?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/ca/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/oily-skin) — High fit — [CA$31.95 at Amazon](https://www.amazon.ca/dp/B0CYQSGR5P?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Effaclar Mask](https://lovi.care/skincare/ca/p/la-roche-posay/effaclar-mask/for/oily-skin) — Average fit — [CA$30.95 at Amazon](https://www.amazon.ca/dp/B06XH1WJNR?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Paula's Choice routine · CA$357.38 · 87% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B0CB3PXRQN&Quantity.1=1&ASIN.2=B0DX19HGD4&Quantity.2=1&ASIN.3=B08QTT1QBX&Quantity.3=1&ASIN.4=B09SN5B88W&Quantity.4=1&ASIN.5=B0CKWNT299&Quantity.5=1&ASIN.6=B001VMJSCW&Quantity.6=1&ASIN.7=B09VCP4J1N&Quantity.7=1&AssociateTag=lovi-care-web-routine0a-20) [Buy La Roche-Posay routine · CA$286.80 · 83% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B0CZ3YFMWQ&Quantity.1=1&ASIN.2=B0CJMZB63M&Quantity.2=1&ASIN.3=B07942ZQBT&Quantity.3=1&ASIN.4=B08BMV5VDL&Quantity.4=1&ASIN.5=B005EZSUS0&Quantity.5=1&ASIN.6=B09SN5B88W&Quantity.6=1&ASIN.7=B0CYQSGR5P&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B06XH1WJNR&Quantity.9=1&AssociateTag=lovi-care-web-routine0a-20) [See multi-brand routine · 96% fit](https://lovi.care/skincare/ca/skin/oily-skin)

### La Roche-Posay vs Paula's Choice routines for combination skin

#### Paula's Choice-focused routine

- Cleanser: [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/ca/p/paula-s-choice/clear-pore-normalizing-cleanser/for/combination-skin) — Superior fit — [CA$54.99 at Amazon](https://www.amazon.ca/dp/B0CB3PXRQN?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Advanced Replenishing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/advanced-replenishing-toner/for/combination-skin) — High fit — [CA$41.00 at Amazon](https://www.amazon.ca/dp/B0DX19HGD4?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Moisturizer](https://lovi.care/skincare/ca/p/paula-s-choice/replenishing-moisturizer/for/combination-skin) — Average fit — [CA$68.00 at Amazon](https://www.amazon.ca/dp/B0DWZP933S?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Youth-Extending Daily Hydrating Fluid SPF 50](https://lovi.care/skincare/ca/p/paula-s-choice/youth-extending-daily-hydrating-fluid-spf-50/for/combination-skin) — High fit — [CA$55.00 at Sephora](https://www.sephora.com/ca/en/product/paulas-choice-resist-youth-extending-daily-hydrating-fluid-spf-50-P511986?skuId=2787026) — Morning
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/ca/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — [CA$23.99 at Amazon](https://www.amazon.ca/dp/B08QTT1QBX?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/ca/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [CA$31.99 at Amazon](https://www.amazon.ca/dp/B0CVRCR6VF?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Niacinamide 20% Treatment](https://lovi.care/skincare/ca/p/paula-s-choice/niacinamide-20-treatment/for/combination-skin) — Superior fit — [CA$84.00 at Amazon](https://www.amazon.ca/dp/B0CKWNT299?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Origins Original Skin Retexturizing Mask with Rose Clay](https://lovi.care/skincare/ca/p/origins/original-skin-retexturizing-mask-with-rose-clay/for/combination-skin) — Superior fit — [CA$50.00 at Amazon](https://www.amazon.ca/dp/B0DV8YNCC5?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

#### La Roche-Posay-focused routine

- Cleanser: [MELA B3 Facial Gel Cleanser](https://lovi.care/skincare/ca/p/la-roche-posay/mela-b3-facial-gel-cleanser/for/combination-skin) — High fit — [CA$33.00 at Amazon](https://www.amazon.ca/dp/B0CZ3YFMWQ?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [CA$37.60 at Amazon](https://www.amazon.ca/dp/B0CJMZB63M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Toleriane Dermallergo Night Cream](https://lovi.care/skincare/ca/p/la-roche-posay/toleriane-dermallergo-night-cream/for/combination-skin) — High fit — [CA$41.00 at Amazon](https://www.amazon.ca/dp/B09XJWJM44?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Anthelios](https://lovi.care/skincare/ca/p/la-roche-posay/anthelios/for/combination-skin) — Superior fit — [CA$35.95 at Amazon](https://www.amazon.ca/dp/B08BMV5VDL?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Respectissime Waterproof Eye Makeup Remover](https://lovi.care/skincare/ca/p/la-roche-posay/respectissime-waterproof-eye-makeup-remover/for/combination-skin) — Average fit — [CA$24.50 at Amazon](https://www.amazon.ca/dp/B000V3MGFS?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/ca/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [CA$31.99 at Amazon](https://www.amazon.ca/dp/B0CVRCR6VF?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Effaclar Ultra Concentrated Serum](https://lovi.care/skincare/ca/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/combination-skin) — High fit — [CA$64.00 at Amazon](https://www.amazon.ca/dp/B08H81SZKH?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Effaclar Mask](https://lovi.care/skincare/ca/p/la-roche-posay/effaclar-mask/for/combination-skin) — Average fit — [CA$30.95 at Amazon](https://www.amazon.ca/dp/B06XH1WJNR?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Paula's Choice routine · CA$383.47 · 88% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B0CB3PXRQN&Quantity.1=1&ASIN.2=B0DX19HGD4&Quantity.2=1&ASIN.3=B0DWZP933S&Quantity.3=1&ASIN.4=B08QTT1QBX&Quantity.4=1&ASIN.5=B0CVRCR6VF&Quantity.5=1&ASIN.6=B0CKWNT299&Quantity.6=1&ASIN.7=B001VMJSCW&Quantity.7=1&ASIN.8=B0DV8YNCC5&Quantity.8=1&AssociateTag=lovi-care-web-routine0a-20) [Buy La Roche-Posay routine · CA$328.49 · 85% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B0CZ3YFMWQ&Quantity.1=1&ASIN.2=B0CJMZB63M&Quantity.2=1&ASIN.3=B09XJWJM44&Quantity.3=1&ASIN.4=B08BMV5VDL&Quantity.4=1&ASIN.5=B000V3MGFS&Quantity.5=1&ASIN.6=B0CVRCR6VF&Quantity.6=1&ASIN.7=B08H81SZKH&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B06XH1WJNR&Quantity.9=1&AssociateTag=lovi-care-web-routine0a-20) [See multi-brand routine · 96% fit](https://lovi.care/skincare/ca/skin/combination-skin)

## Questions and answers

### La Roche-Posay or Paula's Choice: which is better?

La Roche-Posay is a better fit for dry skin and skin with dark spots, where Lovi rates its routines as Superior, whereas Paula's Choice is a better fit for acne clearing and oil control. Both brands offer high routine fits for combination, sensitive, and mature skin types on the products on this page.

### What is the difference between La Roche-Posay and Paula's Choice?

La Roche-Posay is a French brand founded in 1975 and owned by L'Oréal, featuring fragrance across select products, whereas Paula's Choice is an American brand founded in 1995 and owned by Unilever with entirely fragrance-free products. Both brands offer routines rated High for oily, combination, sensitive, acne-prone, mature, and dry sensitive skin, while La Roche-Posay's routine fit is Superior for dry skin and skin with dark spots compared to Paula's Choice's High rating for those types.

### La Roche-Posay or Paula's Choice for dry skin?

La Roche-Posay is a superior choice for dry skin compared to Paula's Choice. Lovi rates the routine fit for dry skin as Superior for La Roche-Posay and High for Paula's Choice.

### La Roche-Posay or Paula's Choice: which cleanser is better?

Both La Roche-Posay and Paula's Choice offer cleansers with high fit levels for various skin types, but reviewers note that La Roche-Posay does better for fragrance-free and gentle formulas and hydration, while Paula's Choice does better for acne clearing and oil control. For instance, the Paula's Choice CLEAR Pore Normalizing Cleanser has a superior fit for oily acne-prone skin, oily skin, and acne-prone skin, whereas the La Roche-Posay Toleriane Hydrating [Foaming](https://lovi.care/skincare/ca/ingredients/foaming) Gel has a superior fit for dry skin and sensitive skin.

### Which is more affordable, La Roche-Posay or Paula's Choice?

Price, value, and size concerns are often mentioned for La Roche-Posay, while high price and packaging issues are mostly noted for Paula's Choice.

### Between La Roche-Posay and Paula's Choice, which brand offers better options for fading dark spots?

Paula's Choice offers better options for brightening and fading dark spots. Lovi rates the routine fit for skin with dark spots as Superior for La Roche-Posay and High for Paula's Choice.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### How do the fragrance options differ between La Roche-Posay and Paula's Choice products?

La Roche-Posay includes fragrance in several of the products on this page, while every product from Paula's Choice is fragrance-free. Shoppers sensitive to scents may find that Paula's Choice offers a more consistent fragrance-free selection across its range.

### Which brand performs better for hydration and moisture according to review themes?

La Roche-Posay performs better for hydration and moisture according to review themes. Lovi rates the routine fit for dry skin as Superior for La Roche-Posay and High for Paula's Choice.

### La Roche-Posay or Paula's Choice for oily skin?

La Roche-Posay and Paula's Choice both fit oily skin at a High level. Reviewers note that Paula's Choice does better for acne clearing and oil control, while La Roche-Posay does better for hydration and moisture.

### La Roche-Posay or Paula's Choice: which moisturizer is better?

La Roche-Posay is better for dry skin, as Lovi rates its dry-skin routine as Superior compared to the High fit level for Paula's Choice. Reviewers also note that La Roche-Posay does better for hydration and moisture, while Paula's Choice does better for oil control and acne clearing.

### La Roche-Posay or Paula's Choice for sensitive skin?

Both La Roche-Posay and Paula's Choice fit sensitive skin at a High level on this page. La Roche-Posay does better for fragrance-free and gentle formulas, while every product on the Paula's Choice page lists no fragrance.

### La Roche-Posay or Paula's Choice: which sunscreen is better?

La Roche-Posay is a better choice for sunscreens on this page, as its Anthelios products achieve a Superior fit level for skin with dark spots, sensitive skin, combination skin, acne-prone skin, mature skin, and oily skin. Paula's Choice offers fewer sunscreen options with lower fit levels overall.

### La Roche-Posay or Paula's Choice for acne-prone skin?

Both brands are a High fit for acne-prone skin, with La Roche-Posay offering products on this page that are fragrance-free and gentle, while Paula's Choice focuses on acne clearing and oil control. [Niacinamide](https://lovi.care/skincare/ca/ingredients/niacinamide) in both brands helps reduce cutaneous pigmentation and control skin aging.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Sodium hyaluronate · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress](https://pubmed.ncbi.nlm.nih.gov/11181450/) Epigallocatechin gallate · Carcinogenesis, 2001
- [Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments](https://pubmed.ncbi.nlm.nih.gov/21952107/) Rice bran oil · Journal of Nanobiotechnology, 2011
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes](https://pubmed.ncbi.nlm.nih.gov/23096708/) Epigallocatechin gallate · The Journal of Investigative Dermatology, 2013
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome](https://pubmed.ncbi.nlm.nih.gov/33526970/) Lactobacillus · International Journal of Medical Sciences, 2021
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol vitamin e, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol, Bakuchiol · The British Journal of Dermatology, 2019
- [Vesicular carriers containing phenylethyl resorcinol for topical delivery system; liposomes, transfersomes and invasomes](https://pubmed.ncbi.nlm.nih.gov/32104421/) Phenylethyl resorcinol · Asian Journal of Pharmaceutical Sciences, 2018
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women](https://pubmed.ncbi.nlm.nih.gov/25378941/) Glutathione · Clinical, Cosmetic and Investigational Dermatology, 2014
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects](https://pubmed.ncbi.nlm.nih.gov/26648450/) Ubiquinone · BioFactors, 2015
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin](https://pubmed.ncbi.nlm.nih.gov/30822414/) Epigallocatechin gallate · The Journal of Investigative Dermatology, 2019
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Ethosomes of Phenylethyl Resorcinol as Vesicular Delivery System for Skin Lightening Applications](https://pubmed.ncbi.nlm.nih.gov/28804723/) Phenylethyl resorcinol · BioMed Research International, 2017
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ferulic acid, Tocopherol, Ascorbic acid, Tocopherol vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of probiotic-derived lotion from Lactobacillus paracasei MSMC 39-1 in mild to moderate acne vulgaris, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/35384257/) Lactobacillus · Journal of Cosmetic Dermatology, 2022
- [Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo](https://pubmed.ncbi.nlm.nih.gov/25381913/) Licorice root extract, Glycyrrhiza glabra root extract licorice root extract · Experimental Dermatology, 2015
- [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia oleifera leaf extract camellia sinensis leaf extract, Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The clinical effect of glutathione on skin color and other related skin conditions: A systematic review](https://pubmed.ncbi.nlm.nih.gov/30895708/) Glutathione · Journal of Cosmetic Dermatology, 2019
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene usp retinoid acne treatment, Adapalene · American Journal of Clinical Dermatology, 2018
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine · The British Journal of Dermatology, 2010
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007
- [A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen](https://pubmed.ncbi.nlm.nih.gov/20374604/) Retinyl propionate · The British Journal of Dermatology, 2010
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid, Salicylic acid bha · BioMed Research International, 2020
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene, Adapalene usp retinoid acne treatment · Archives of Dermatological Research, 2022
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Topical glutathione amino acid precursors protect skin against environmental and oxidative stress](https://pubmed.ncbi.nlm.nih.gov/38189670/) Glutathione · Journal of the European Academy of Dermatology and Venereology, 2024
- [An Open-Label Single-Arm, Monocentric Study Assessing the Efficacy and Safety of Natural Pterostilbene (Pterocarpus marsupium) for Skin Brightening and Antiaging Effects](https://pubmed.ncbi.nlm.nih.gov/32099438/) Blueberry fruit extract · Clinical, Cosmetic and Investigational Dermatology, 2020
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract, Madecassoside · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [In vivo skin irritation potential of a Castanea sativa (Chestnut) leaf extract, a putative natural antioxidant for topical application](https://pubmed.ncbi.nlm.nih.gov/18793273/) Chestnut leaf extract · Basic & Clinical Pharmacology & Toxicology, 2008
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid, Salicylic acid bha · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc · Journal of Controlled Release, 2025
- [Clinical evaluation of photoprotective effect by a topical antioxidants combination (tocopherols and tocotrienols)](https://pubmed.ncbi.nlm.nih.gov/21917024/) Tocotrienols · Journal of the European Academy of Dermatology and Venereology, 2012
- [Tocotrienol-rich fraction attenuates UV-induced inflammaging: A bench to bedside study](https://pubmed.ncbi.nlm.nih.gov/28952200/) Tocotrienols · Journal of Cosmetic Dermatology, 2018
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Argilla · Forschende Komplementarmedizin, 2012
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol](https://pubmed.ncbi.nlm.nih.gov/27391637/) Hexylresorcinol · Journal of Drugs in Dermatology, 2016
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid, Salicylic acid bha · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Neurosensine · Journal of the European Academy of Dermatology and Venereology, 2016
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [2-Mercaptonicotinoyl glycine prevents UV-induced skin darkening and delayed tanning in healthy subjects: A randomized controlled clinical study](https://pubmed.ncbi.nlm.nih.gov/38372022/) 2-mercaptonicotinoyl glycine · Journal of Cosmetic Dermatology, 2024
- [A Bayesian network meta-analysis of 14 molecules inhibiting UV daylight-induced pigmentation](https://pubmed.ncbi.nlm.nih.gov/38433524/) 2-mercaptonicotinoyl glycine · Journal of the European Academy of Dermatology and Venereology, 2024
- [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide](https://pubmed.ncbi.nlm.nih.gov/34958693/) Hexylresorcinol · International Journal of Cosmetic Science, 2022
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study](https://pubmed.ncbi.nlm.nih.gov/36698447/) Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis oil · Biomaterials Advances, 2022
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Capryloyl salicylic acid, Citric acid · Journal of Cosmetic Dermatology, 2021
- [Amino acid complex (AAComplex) benefits in cosmetic products: In vitro and in vivo clinical studies](https://pubmed.ncbi.nlm.nih.gov/34694692/) Complex amino acid · Journal of Cosmetic Dermatology, 2022
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia oleifera leaf extract camellia sinensis leaf extract, Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin](https://pubmed.ncbi.nlm.nih.gov/19146601/) Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2008
- [Comparative benefit of two thermal spring waters after photodynamic therapy procedure](https://pubmed.ncbi.nlm.nih.gov/17348993/) La roche-posay thermal spring water · Journal of Cosmetic Dermatology, 2007
- [Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations](https://pubmed.ncbi.nlm.nih.gov/33561977/) Complex amino acid · International Journal of Molecular Sciences, 2021
- [Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin](https://pubmed.ncbi.nlm.nih.gov/31033161/) Butylene glycol · Journal of Cosmetic Dermatology, 2019
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [Apple Extract (Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin](https://pubmed.ncbi.nlm.nih.gov/32242497/) Pyrus malus fruit extract · Rejuvenation Research, 2020
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Comprehensive assessment of the efficacy and safety of a clay mask in oily and acne skin](https://pubmed.ncbi.nlm.nih.gov/38009030/) Argilla · Skin Research and Technology, 2023
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome](https://pubmed.ncbi.nlm.nih.gov/37990616/) Sodium lauroyl sarcosinate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) Acetyl glucosamine · Advanced Pharmaceutical Bulletin, 2016
- [Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids](https://pubmed.ncbi.nlm.nih.gov/12482041/) Phytosphingosine · Journal of the European Academy of Dermatology and Venereology, 2002
- [Stability, antioxidant activity, in vivo safety and efficacy of creams with standardized wild apple fruit extract: a comparison of conventional and biodegradable emulsifiers](https://pubmed.ncbi.nlm.nih.gov/31050807/) Pyrus malus fruit extract · International Journal of Cosmetic Science, 2019
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis oil, Borago officinalis seed oil · Lipids, 2020
- [Development, Characterization, and Clinical Investigation of a New Topical Emulsion System Containing a Castanea sativa Spiny Burs Active Extract](https://pubmed.ncbi.nlm.nih.gov/34683927/) Chestnut leaf extract · Pharmaceutics, 2021
- [A dermocosmetic formulation containing Vichy volcanic mineralizing water, Vitreoscilla filiformis extract, niacinamide, hyaluronic acid, and vitamin E regenerates and repairs acutely stressed skin](https://pubmed.ncbi.nlm.nih.gov/34979590/) Vitreoscilla ferment · Journal of the European Academy of Dermatology and Venereology, 2022
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Hydrolyzed yeast extract · Journal of Clinical Medicine, 2023
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia oleifera leaf extract camellia sinensis leaf extract · Molecules, 2024
- [Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug](https://pubmed.ncbi.nlm.nih.gov/17671830/) Glycine soja oil soybean oil · Pharmaceutical Research, 2008
- [Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda](https://pubmed.ncbi.nlm.nih.gov/35388606/) Mandelic acid · Journal of Cosmetic Dermatology, 2022
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/41142247/) 2-mercaptonicotinoyl glycine · Frontiers in Pharmacology, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [A multicenter, double-blind study to evaluate the efficacy and safety of 2 treatments in participants with mild to moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/22838094/) Micro-exfoliating lha · Cutis, 2012
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Standardized wild apple fruit extract as a bioactive agent in dermocosmetic products for efficacy skin hydration-In vitro and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/35048513/) Pyrus malus fruit extract · Journal of Cosmetic Dermatology, 2022
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites](https://pubmed.ncbi.nlm.nih.gov/23438139/) Retinyl palmitate · Journal of Cosmetic Dermatology, 2013
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Avobenzone · European Journal of Pharmaceutical Sciences, 2023
- [Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance](https://pubmed.ncbi.nlm.nih.gov/36502500/) Hexylresorcinol · Archives of Dermatological Research, 2023
- [Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/32870553/) Prebiotic thermal water, La roche-posay thermal spring water, Thermal spring water · Journal of the European Academy of Dermatology and Venereology, 2020
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Capryloyl salicylic acid · Journal of Drugs in Dermatology, 2013
- [Histometric assessment of the age-related skin response to 2-hydroxy-5-octanoyl benzoic acid](https://pubmed.ncbi.nlm.nih.gov/9603669/) Capryloyl salicylic acid · Skin Pharmacology and Applied Skin Physiology, 1998
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Improving the outcome of treating striae gravidarum by combined therapies using topical β-glucan and 1565-nm non-ablative fractional laser: A prospective randomized vehicle-controlled parallel group study](https://pubmed.ncbi.nlm.nih.gov/35570397/) Beta-glucan · The Journal of Dermatology, 2022
- [Treatment of Stretch Marks Using a New Formulation Combining Nanofractional Radiofrequency Plus Magnetic Nanofractional Radiofrequency](https://pubmed.ncbi.nlm.nih.gov/37171578/) Beta-glucan · Dermatology and Therapy, 2023
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study](https://pubmed.ncbi.nlm.nih.gov/38553920/) Prebiotic thermal water, La roche-posay thermal spring water, Thermal spring water, La roche-posay prebiotic thermal water, Thermal water · The Medical Journal of Malaysia, 2024
- [Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/36999489/) Micro-exfoliating lha · Journal of Cosmetic Dermatology, 2023
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octinoxate · Archives of Dermatological Research, 2024
- [Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study](https://pubmed.ncbi.nlm.nih.gov/41487026/) Zinc gluconate · Journal of Cosmetic Dermatology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits](https://pubmed.ncbi.nlm.nih.gov/39964201/) Palmitoyl hexapeptide-12 · ACS Applied Bio Materials, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract purslane extract · Cutaneous and Ocular Toxicology, 2022
- [Topical application of retinyl propionate, 4 hexyl resorcinol, and niacinamide reverses molecular and clinical features of ageing](https://pubmed.ncbi.nlm.nih.gov/38685700/) Retinyl propionate · International Journal of Cosmetic Science, 2024
- [Retinyl propionate and climbazole combination demonstrates clinical improvement to the appearance of hyperpigmentation and deep wrinkling with minimal irritation](https://pubmed.ncbi.nlm.nih.gov/28733999/) Retinyl propionate · International Journal of Cosmetic Science, 2017
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter, Saccharide isomerate · Lasers in Medical Science, 2025
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate, Homosalate · Journal of Drugs in Dermatology, 2025
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Effects of an ultraviolet B radiation absorber on photocarcinogenesis in hairless albino mice](https://pubmed.ncbi.nlm.nih.gov/19365102/) Ethylhexyl triazone · Skin Pharmacology and Physiology, 2009
- [In vitro analysis of immunoprotective effects of topical sunscreens](https://pubmed.ncbi.nlm.nih.gov/20693002/) Ethylhexyl triazone · Toxicology in Vitro, 1994
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract purslane extract · Cutaneous and Ocular Toxicology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025

## The brands

- French skincare: [La Roche-Posay](https://lovi.care/skincare/ca/brands/la-roche-posay)
- American skincare: [Paula's Choice](https://lovi.care/skincare/ca/brands/paula-s-choice)

## More comparisons

- [SKIN1004 vs La Roche-Posay](https://lovi.care/skincare/ca/compare/skin1004-vs-la-roche-posay)
- [SKIN1004 vs Paula's Choice](https://lovi.care/skincare/ca/compare/skin1004-vs-paula-s-choice)
- [Anua vs La Roche-Posay](https://lovi.care/skincare/ca/compare/anua-vs-la-roche-posay)
- [Anua vs Paula's Choice](https://lovi.care/skincare/ca/compare/anua-vs-paula-s-choice)
- [Medicube vs La Roche-Posay](https://lovi.care/skincare/ca/compare/medicube-vs-la-roche-posay)
- [Medicube vs Paula's Choice](https://lovi.care/skincare/ca/compare/medicube-vs-paula-s-choice)
- [The Ordinary vs La Roche-Posay](https://lovi.care/skincare/ca/compare/the-ordinary-vs-la-roche-posay)
- [The Ordinary vs Paula's Choice](https://lovi.care/skincare/ca/compare/the-ordinary-vs-paula-s-choice)
- [Beauty of Joseon vs La Roche-Posay](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-la-roche-posay)
- [Beauty of Joseon vs Paula's Choice](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-paula-s-choice)
- [COSRX vs La Roche-Posay](https://lovi.care/skincare/ca/compare/cosrx-vs-la-roche-posay)
- [COSRX vs Paula's Choice](https://lovi.care/skincare/ca/compare/cosrx-vs-paula-s-choice)
- [CeraVe vs La Roche-Posay](https://lovi.care/skincare/ca/compare/cerave-vs-la-roche-posay)
- [CeraVe vs Paula's Choice](https://lovi.care/skincare/ca/compare/cerave-vs-paula-s-choice)
- [La Roche-Posay vs Dr. Althea](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-dr-althea)
- [La Roche-Posay vs Some By Mi](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-some-by-mi)
- [La Roche-Posay vs Torriden](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-torriden)
- [La Roche-Posay vs celimax](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-celimax)
- [La Roche-Posay vs Purito](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-purito)
- [La Roche-Posay vs Cetaphil](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-cetaphil)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/la-roche-posay-vs-paula-s-choice
- United Kingdom: https://lovi.care/skincare/uk/compare/la-roche-posay-vs-paula-s-choice
- Ireland: https://lovi.care/skincare/ie/compare/la-roche-posay-vs-paula-s-choice
- Germany: https://lovi.care/skincare/de/compare/la-roche-posay-vs-paula-s-choice
- France: https://lovi.care/skincare/fr/compare/la-roche-posay-vs-paula-s-choice
- Italy: https://lovi.care/skincare/it/compare/la-roche-posay-vs-paula-s-choice
- Netherlands: https://lovi.care/skincare/nl/compare/la-roche-posay-vs-paula-s-choice
- Spain: https://lovi.care/skincare/es/compare/la-roche-posay-vs-paula-s-choice
- Canada: https://lovi.care/skincare/ca/compare/la-roche-posay-vs-paula-s-choice (this page)
- Australia: https://lovi.care/skincare/au/compare/la-roche-posay-vs-paula-s-choice
- Singapore: https://lovi.care/skincare/sg/compare/la-roche-posay-vs-paula-s-choice
- Saudi Arabia: https://lovi.care/skincare/sa/compare/la-roche-posay-vs-paula-s-choice
- United Arab Emirates: https://lovi.care/skincare/ae/compare/la-roche-posay-vs-paula-s-choice
