# Hada Labo vs NEOCUTIS

Page: https://lovi.care/skincare/ca/compare/hada-labo-vs-neocutis

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Hada Labo and NEOCUTIS are well-regarded skincare brands originating from Japan and Switzerland, respectively. The Japanese brand is known for its targeted toners, gentle makeup removers, and deeply hydrating moisturizers featuring key components like [hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid) derivatives, while the Swiss brand is celebrated for its refined [serums](https://lovi.care/skincare/ca/ingredients/serum) and moisturizers that utilize restorative ingredients like [proprietary](https://lovi.care/skincare/ca/ingredients/proprietary) peptides. The former suits dry, sensitive, oily, and combination skin types best, whereas the latter is ideally suited for mature, dry, and stressed skin due to its deeply restorative properties. These distinct lines differ primarily in their formulation origins and specific target concerns, with both offering balanced, gentle care to maintain healthy, comfortable skin.

Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..

[en.wikipedia.org](https://en.wikipedia.org/wiki/Hada_Labo) [hadalabosa.co.za](https://hadalabosa.co.za/about-hada-labo/) [hadalabotokyo.pl](https://www.hadalabotokyo.pl/en/the-world-of-hada-labo/brand-history/)

NEOCUTIS is a Swiss skincare brand founded in 2003 and owned by Merz Holding GmbH & Co. KG since 2013.

[businesswire.com](https://www.businesswire.com/news/home/20260716926041/en/Merz-Completes-Inaugural-%E2%82%AC450-Million-Schuldschein-Loan-Issuance) [gcimagazine.com](https://www.gcimagazine.com/brands-products/skin-care/news/21870673/merz-to-purchase-neocutis)

This page compares some of the most popular Hada Labo and NEOCUTIS products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg1ffe44cf35).

### Popular Hada Labo vs NEOCUTIS products

#### Hada Labo

- [Gokujyun Lotion](https://lovi.care/skincare/ca/p/hada-labo/gokujyun-lotion/for/dry-skin) — Superior fit
- [Gokujun Premium](https://lovi.care/skincare/ca/p/hada-labo/gokujun-premium/for/dry-skin) — Superior fit
- [Shirojyun Premium Whitening Lotion](https://lovi.care/skincare/ca/p/hada-labo/shirojyun-premium-whitening-lotion/for/dry-skin) — High fit
- [Gokujyun Cleansing Oil](https://lovi.care/skincare/ca/p/hada-labo/gokujyun-cleansing-oil/for/dry-skin) — Superior fit
- [Gokujyun Perfect Gel](https://lovi.care/skincare/ca/p/hada-labo/gokujyun-perfect-gel/for/dry-skin) — High fit
- [Premium Whitening Lotion (Light)](https://lovi.care/skincare/ca/p/hada-labo/premium-whitening-lotion-light/for/dry-sensitive-skin) — High fit

#### NEOCUTIS

- [Bio Serum Firm](https://lovi.care/skincare/ca/p/neocutis/bio-serum-firm/for/mature-skin) — High fit
- [lumière](https://lovi.care/skincare/ca/p/neocutis/lumiere/for/dry-skin) — Average fit

## Questions and answers

### Hada Labo or NEOCUTIS: which is better?

Both Hada Labo and NEOCUTIS offer fragrance-free options, with Hada Labo focusing heavily on deep hydration through [hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid) while NEOCUTIS provides targeted anti-aging and moisturizing products like Bio [Serum](https://lovi.care/skincare/ca/ingredients/serum) Firm. Reviewers frequently praise Hada Labo for its value and lightweight toners, though some note sticky finishes or potential breakouts.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between Hada Labo and NEOCUTIS?

Hada Labo focuses on hydrating toners, cleansers, and gels featuring hyaluronic acid with fragrance-free formulas, whereas NEOCUTIS offers specialized options like Bio Serum Firm and lumière for mature and dry skin. Both brands provide fragrance-free products on this page.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Hada Labo or NEOCUTIS: which moisturizer is better?

Hada Labo Gokujyun Perfect Gel is a popular moisturizer on this page featuring hyaluronic acid, which helps hydrate and improve skin quality. Topical hyaluronic acid helps maintain moisture in the skin.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, Hada Labo or NEOCUTIS?

Hada Labo offers value and versatility as part of its reviewed benefits, whereas NEOCUTIS products on this page do not list affordability highlights.

### Which causes fewer breakouts, Hada Labo or NEOCUTIS?

NEOCUTIS is unlikely to cause breakouts based on the products on this page, whereas Hada Labo reviewers sometimes mention breakouts and clogged pores.

### How do the founding years and corporate ownership of Hada Labo and NEOCUTIS compare?

Hada Labo was founded in Japan in 2004 and is owned by Rohto Pharmaceutical, whereas NEOCUTIS was founded in Switzerland in 2003 and has been owned by Merz Holding since 2013.

### Which brand has more products listed on the page with a Superior fit level for dry skin?

Hada Labo has more products listed on the page with a Superior fit level for dry skin, including the Gokujyun Lotion, Gokujun Premium, and Gokujyun Cleansing Oil, whereas NEOCUTIS has none with a Superior fit level for dry skin.

### Are there any fragrance-containing products in either the Hada Labo or NEOCUTIS lineups?

No, neither brand includes fragrance-containing items because every product on this page lists no fragrance in its ingredients.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramide · Scientific Reports, 2022
- [Preparation and characterization of a lecithin nanoemulsion as a topical delivery system](https://pubmed.ncbi.nlm.nih.gov/20652152/) Hydroxylated lecithin · Nanoscale Research Letters, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1 acetate, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Encapsulation of alpha arbutin, a depigmenting agent, in nanosized ethosomes: Invitro and invivo human studies](https://pubmed.ncbi.nlm.nih.gov/37681127/) Alpha-arbutin · Heliyon, 2023
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin](https://pubmed.ncbi.nlm.nih.gov/22236139/) Magnesium ascorbyl phosphate · Photochemistry and Photobiology, 2012
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [The anti-wrinkles properties of sodium acetylated hyaluronate](https://pubmed.ncbi.nlm.nih.gov/34708918/) Sodium acetylhyaluronate · Journal of Cosmetic Dermatology, 2022
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Comparative Study on Epidermal Moisturizing Effects and Hydration Mechanisms of Rice-Derived Glucosylceramides and Ceramides](https://pubmed.ncbi.nlm.nih.gov/36613524/) Glucosyl ceramide · International Journal of Molecular Sciences, 2022
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 3-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Combined Effect of Silybin and Sodium Acetylated Hyaluronate on UV-Induced Photoaging](https://pubmed.ncbi.nlm.nih.gov/42728863/) Sodium acetylhyaluronate · Skin Research and Technology, 2026
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 acetate, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1 acetate · International Journal of Cosmetic Science, 2026

## The brands

- Japanese skincare: [Hada Labo](https://lovi.care/skincare/ca/brands/hada-labo)
- Swiss skincare: [NEOCUTIS](https://lovi.care/skincare/ca/brands/neocutis)

## More comparisons

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- [The Ordinary vs Hada Labo](https://lovi.care/skincare/ca/compare/the-ordinary-vs-hada-labo)
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- [CeraVe vs Hada Labo](https://lovi.care/skincare/ca/compare/cerave-vs-hada-labo)
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- [La Roche-Posay vs Hada Labo](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-hada-labo)
- [La Roche-Posay vs NEOCUTIS](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-neocutis)
- [Dr. Althea vs Hada Labo](https://lovi.care/skincare/ca/compare/dr-althea-vs-hada-labo)
- [Dr. Althea vs NEOCUTIS](https://lovi.care/skincare/ca/compare/dr-althea-vs-neocutis)
- [Some By Mi vs Hada Labo](https://lovi.care/skincare/ca/compare/some-by-mi-vs-hada-labo)
- [Some By Mi vs NEOCUTIS](https://lovi.care/skincare/ca/compare/some-by-mi-vs-neocutis)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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