# Galderma vs Sebamed Page: https://lovi.care/skincare/ca/compare/galderma-vs-sebamed The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada. Galderma and Sebamed are distinct dermatological companies, with the former being a Swiss brand founded in 1981 and the latter a German enterprise established in 1967. The Swiss brand provides targeted [serums](https://lovi.care/skincare/ca/ingredients/serum) featuring key ingredients like [adapalene](https://lovi.care/skincare/ca/ingredients/adapalene) and [benzoyl peroxide](https://lovi.care/skincare/ca/ingredients/benzoyl-peroxide) for oily and combination skin, while the German brand is known for thoughtful moisturizers and gentle cleansers with scientifically balanced formulas that utilize a skin-neutral pH. Consequently, the Swiss offerings excel for acne-prone, pigmented, and mature skin through products such as Epiduo Gel and Benzac AC, whereas the German options best suit sensitive, reactive, and problematic skin with reliable staples like its Facial Cleanser and Clear Face Care Gel. Ultimately, both brands differ fundamentally in their formulations and primary skin type compatibilities while maintaining a steadfast dedication to dermatological health. Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG. [en.wikipedia.org](https://en.wikipedia.org/wiki/Galderma) Sebamed is a German skincare brand founded in 1967 and owned by Sebapharma GmbH & Co. KG. [sebamed.ae](https://sebamed.ae/en/article/2/Sebapharma) [sebamed.com](https://sebamed.com/en/info/company/about-us/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Sebamed) [de.wikipedia.org](https://de.wikipedia.org/wiki/Sebamed) This page compares some of the most popular Galderma and Sebamed products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg539ddefcfd). ### Popular Galderma vs Sebamed products #### Galderma - [Epiduo Gel](https://lovi.care/skincare/ca/p/galderma/epiduo-gel/for/acne-prone-skin) — High fit - [Benzac AC 5](https://lovi.care/skincare/ca/p/galderma/benzac-ac-5/for/oily-acne-prone-skin) — High fit — [CA$45.40 at Amazon](https://www.amazon.ca/dp/B0H7FDLC2T?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Benzac AC Mild Strength 2.5% Acne Gel](https://lovi.care/skincare/ca/p/galderma/benzac-ac-mild-strength-2-5-acne-gel/for/oily-acne-prone-skin) — High fit #### Sebamed - [Clear Face Care Gel](https://lovi.care/skincare/ca/p/sebamed/clear-face-care-gel/for/oily-acne-prone-skin) — High fit — [CA$48.35 at Amazon](https://www.amazon.ca/dp/B003NTJKHY?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1) - [Facial Cleanser](https://lovi.care/skincare/ca/p/sebamed/facial-cleanser/for/combination-skin) — High fit ## Questions and answers ### Galderma or Sebamed: which is better? Galderma is a better fit for oily, combination, and oily acne-prone skin, while Sebamed also works well for sensitive skin. Reviewers note that Galderma provides effective acne-clearing [serums](https://lovi.care/skincare/ca/ingredients/serum), though users may experience severe dryness and peeling. [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/) ### What is the difference between Galderma and Sebamed? Galderma provides effective acne-clearing serums that Lovi rates as High for oily and acne-prone skin, whereas Sebamed offers products like the Facial Cleanser that Lovi rates as High across several skin types including sensitive skin. The products on this page from both brands list no fragrance. However, Galderma reviewers mostly mention severe dryness, peeling, and irritation. [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/) ### Which is more affordable, Galderma or Sebamed? The products on this page for both Galderma and Sebamed do not list pricing information, so a comparison of affordability is not possible from the provided page facts. ### Which causes fewer breakouts, Galderma or Sebamed? Galderma's products on this page have a High Lovi fit for oily acne-prone skin and are effective acne-clearing serums, though they may cause severe dryness and peeling. Sebamed's Clear Face Care Gel has a High fit for oily acne-prone skin, while its Facial Cleanser has a High fit for acne-prone skin. [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/) ### Which brand has products formulated specifically as serums, Galderma or Sebamed? Galderma has products on this page formulated specifically as serums, whereas Sebamed offers a moisturizer and a cleanser. These Galderma serums help clear acne effectively but may cause severe dryness, peeling, and irritation. [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) ### How do the founding years and countries of origin compare between Galderma and Sebamed? Galderma was founded in 1981 in Switzerland, whereas Sebamed was founded earlier in 1967 in Germany. ### Do any of the products from Galderma or Sebamed contain fragrance? Every product on this page from both Galderma and Sebamed lists no fragrance in its ingredients. ## Research behind their key ingredients - [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022 - [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002 - [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016 - [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018 - [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide, Benzoyl peroxide 25mg g · The Cochrane Database of Systematic Reviews, 2020 - [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene · American Journal of Clinical Dermatology, 2018 - [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of Shoulder and Elbow Surgery, 2021 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide, Benzoyl peroxide 25mg g · American Journal of Clinical Dermatology, 2022 - [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017 - [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene · Archives of Dermatological Research, 2022 - [Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15](https://pubmed.ncbi.nlm.nih.gov/32224894/) Silicon dioxide · Antioxidants, 2020 - [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020 - [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel bark extract · Phytochemistry, 2001 - [Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection](https://pubmed.ncbi.nlm.nih.gov/32395645/) Silicon dioxide · Heliyon, 2020 - [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023 - [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of the American Academy of Dermatology, 2023 - [Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation](https://pubmed.ncbi.nlm.nih.gov/37367119/) Carbomer 940 · Gels, 2023 - [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013 - [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025 ## The brands - Swiss skincare: [Galderma](https://lovi.care/skincare/ca/brands/galderma) - German skincare: [Sebamed](https://lovi.care/skincare/ca/brands/sebamed) ## More comparisons - [SKIN1004 vs Galderma](https://lovi.care/skincare/ca/compare/skin1004-vs-galderma) - [SKIN1004 vs Sebamed](https://lovi.care/skincare/ca/compare/skin1004-vs-sebamed) - [Anua vs Galderma](https://lovi.care/skincare/ca/compare/anua-vs-galderma) - [Anua vs Sebamed](https://lovi.care/skincare/ca/compare/anua-vs-sebamed) - [Medicube vs Galderma](https://lovi.care/skincare/ca/compare/medicube-vs-galderma) - [Medicube vs Sebamed](https://lovi.care/skincare/ca/compare/medicube-vs-sebamed) - [The Ordinary vs Galderma](https://lovi.care/skincare/ca/compare/the-ordinary-vs-galderma) - [The Ordinary vs Sebamed](https://lovi.care/skincare/ca/compare/the-ordinary-vs-sebamed) - [Beauty of Joseon vs Galderma](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-galderma) - [Beauty of Joseon vs Sebamed](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-sebamed) - [COSRX vs Galderma](https://lovi.care/skincare/ca/compare/cosrx-vs-galderma) - [COSRX vs Sebamed](https://lovi.care/skincare/ca/compare/cosrx-vs-sebamed) - [CeraVe vs Galderma](https://lovi.care/skincare/ca/compare/cerave-vs-galderma) - [CeraVe vs Sebamed](https://lovi.care/skincare/ca/compare/cerave-vs-sebamed) - [La Roche-Posay vs Galderma](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-galderma) - [La Roche-Posay vs Sebamed](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-sebamed) - [Dr. Althea vs Galderma](https://lovi.care/skincare/ca/compare/dr-althea-vs-galderma) - [Dr. Althea vs Sebamed](https://lovi.care/skincare/ca/compare/dr-althea-vs-sebamed) - [Some By Mi vs Galderma](https://lovi.care/skincare/ca/compare/some-by-mi-vs-galderma) - [Some By Mi vs Sebamed](https://lovi.care/skincare/ca/compare/some-by-mi-vs-sebamed) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/galderma-vs-sebamed - United Kingdom: https://lovi.care/skincare/uk/compare/galderma-vs-sebamed - Ireland: https://lovi.care/skincare/ie/compare/galderma-vs-sebamed - Germany: https://lovi.care/skincare/de/compare/galderma-vs-sebamed - France: https://lovi.care/skincare/fr/compare/galderma-vs-sebamed - Italy: https://lovi.care/skincare/it/compare/galderma-vs-sebamed - Netherlands: https://lovi.care/skincare/nl/compare/galderma-vs-sebamed - Spain: https://lovi.care/skincare/es/compare/galderma-vs-sebamed - Canada: https://lovi.care/skincare/ca/compare/galderma-vs-sebamed (this page) - Australia: https://lovi.care/skincare/au/compare/galderma-vs-sebamed - Singapore: https://lovi.care/skincare/sg/compare/galderma-vs-sebamed - Saudi Arabia: https://lovi.care/skincare/sa/compare/galderma-vs-sebamed - United Arab Emirates: https://lovi.care/skincare/ae/compare/galderma-vs-sebamed