# Clinique vs Hada Labo

Page: https://lovi.care/skincare/ca/compare/clinique-vs-hada-labo

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Clinique and Hada Labo are established skincare brands offering distinct approaches to daily care, with the American line featuring moisturizers, [serums](https://lovi.care/skincare/ca/ingredients/serum), makeup removers, and eye products rich in [hyaluronic acid](https://lovi.care/skincare/ca/ingredients/hyaluronic-acid), [glycerin](https://lovi.care/skincare/ca/ingredients/glycerin), and [caffeine](https://lovi.care/skincare/ca/ingredients/caffeine), while the Japanese counterpart is known for targeted toners, gentle makeup removers, and deeply hydrating moisturizers. Both brands suit dry, sensitive, and oily skin types, though they differ through Clinique's specialized offerings like the Clarifying Do-Over Peel, for Men Oil-Free Moisturizer, and Smart Clinical Repair Lifting Face + Neck Cream, compared to the brand's Gokujyun Lotion, Shirojyun Premium Whitening Lotion, and Gokujun Premium. Ultimately, each brand utilizes carefully balanced ingredients that work harmoniously to support healthy, comfortable skin.

Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..

[en.wikipedia.org](https://en.wikipedia.org/wiki/Clinique) [elcompanies.com](https://www.elcompanies.com/en/who-we-are/our-heritage) [businesswire.com](https://www.businesswire.com/news/home/20261019083802/en/The-Este-Lauder-Companies-Appoints-Krista-Lee-Berger-Senior-Vice-President-Global-Marketing-Clinique) [glossy.co](https://www.glossy.co/beauty/glossy-pop-newsletter-clinique-launches-first-ever-creator-led-campaign/)

Hada Labo is a Japanese skincare brand founded in 2004 and owned by Rohto Pharmaceutical Co., Ltd..

[en.wikipedia.org](https://en.wikipedia.org/wiki/Hada_Labo) [hadalabosa.co.za](https://hadalabosa.co.za/about-hada-labo/) [hadalabotokyo.pl](https://www.hadalabotokyo.pl/en/the-world-of-hada-labo/brand-history/)

This page compares some of the most popular Clinique and Hada Labo products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg5ad0d5ce00).

### Popular Clinique vs Hada Labo products

#### Hada Labo

- [Gokujyun Lotion](https://lovi.care/skincare/ca/p/hada-labo/gokujyun-lotion/for/dry-skin) — Superior fit
- [Gokujun Premium](https://lovi.care/skincare/ca/p/hada-labo/gokujun-premium/for/dry-skin) — Superior fit
- [Shirojyun Premium Whitening Lotion](https://lovi.care/skincare/ca/p/hada-labo/shirojyun-premium-whitening-lotion/for/dry-skin) — High fit
- [Gokujyun Cleansing Oil](https://lovi.care/skincare/ca/p/hada-labo/gokujyun-cleansing-oil/for/dry-skin) — Superior fit
- [Gokujyun Perfect Gel](https://lovi.care/skincare/ca/p/hada-labo/gokujyun-perfect-gel/for/dry-skin) — High fit
- [Premium Whitening Lotion (Light)](https://lovi.care/skincare/ca/p/hada-labo/premium-whitening-lotion-light/for/dry-sensitive-skin) — High fit

#### Clinique

- [moisture surge](https://lovi.care/skincare/ca/p/clinique/moisture-surge/for/sensitive-skin) — High fit
- [Take The Day Off Cleansing Balm](https://lovi.care/skincare/ca/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [CA$55.00 at Amazon](https://www.amazon.ca/dp/B0BQHT413D?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Lotion+](https://lovi.care/skincare/ca/p/clinique/dramatically-different-moisturizing-lotion/for/dry-skin) — Average fit — [CA$61.00 at Amazon](https://www.amazon.ca/dp/B00JGLEQAO?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [All About Eyes](https://lovi.care/skincare/ca/p/clinique/all-about-eyes/for/dry-skin) — High fit — [CA$82.00 at Amazon](https://www.amazon.ca/dp/B001IZ0ZFQ?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/ca/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [CA$61.00 at Amazon](https://www.amazon.ca/dp/B00B3RDA9M?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/ca/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [CA$145.00 at Amazon](https://www.amazon.ca/dp/B09FG8TJDD?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Moisture Surge Overnight Mask](https://lovi.care/skincare/ca/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [CA$59.00 at Amazon](https://www.amazon.ca/dp/B00HSZRQQQ?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Clarifying Lotion 2](https://lovi.care/skincare/ca/p/clinique/clarifying-lotion-2/for/oily-acne-prone-skin) — Average fit — [CA$30.00 at Amazon](https://www.amazon.ca/dp/B01FBWEORQ?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)

## People Say

Clinique

Hada Labo

- Hydration and Moisture Often Mentioned Mostly Mentioned “skin drinks it up — Hada Labo Gokujyun Lotion” “Plumps fine lines — Hada Labo Gokujun Premium” “leaves skin soft, smooth, and hydrated — Hada Labo Shirojyun Premium Whitening Lotion” “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
- Gentle and Non-Irritating Formula Mostly Mentioned Mostly Mentioned “never irritated my eyes — Clinique All About Eyes” “No stinging eyes — Clinique Take The Day Off Cleansing Balm” “leaves skin soft and hydrated — Hada Labo Gokujyun Cleansing Oil” “never stings my sensitive skin — Hada Labo Gokujyun Lotion”
- Lightweight and Fast Absorbing Often Mentioned Often Mentioned “sinks in immediately — Clinique moisture surge” “sinks in instantly — Clinique Dramatically Different Moisturizing Gel” “absorbs super quickly — Hada Labo Premium Whitening Lotion (Light)” “absorbs super quickly — Hada Labo Shirojyun Premium Whitening Lotion”
- Makeup Removal Sometimes Noted Sometimes Noted “Melts waterproof mascara — Clinique Take The Day Off Cleansing Balm” “squeaky clean — Clinique all about clean” “removes waterproof mascara easily — Hada Labo Gokujyun Cleansing Oil”
- Exfoliation and Skin Smoothing Often Mentioned Not noted “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum” “gentle enough for everyday — Clinique 7 Day Scrub Cream Rinse-Off Formula” “You will see the dirt with one wipe — Clinique Clarifying Lotion 2”
- Good Value and Great Value Rarely Noted Sometimes Noted “bottle lasts forever — Hada Labo Gokujyun Lotion” “Lasts forever — Hada Labo Gokujun Premium” “lasts forever — Clinique all about clean”
- Texture and Finish Issues Sometimes Noted Often Mentioned “hard to rinse off — Clinique 7 Day Scrub Cream Rinse-Off Formula” “feels sticky to the touch — Clinique moisture surge” “Left an oily film on my T-zone — Clinique Dramatically Different Moisturizing Lotion+” “Tacky residue — Hada Labo Gokujun Premium”
- Breakouts and Acne Sometimes Noted Often Mentioned “Woke up with whiteheads on my chin — Clinique Dramatically Different Moisturizing Lotion+” “gave me tiny bumps — Clinique moisture surge” “gave me tiny bumps — Hada Labo Gokujyun Lotion” “Closed comedones — Hada Labo Gokujun Premium”

## Questions and answers

### Clinique or Hada Labo: which is better?

Hada Labo is better for hydration and value among the products on this page, while both brands offer equal gentleness, lightweight absorption, and makeup removal.

### What is the difference between Clinique and Hada Labo?

Hada Labo does better for hydration and moisture as well as value, while Clinique does better for exfoliation and skin smoothing. Reviewers mention that Hada Labo provides deep hydration with lightweight and fast-absorbing toners, whereas Clinique offers a broader range of products including targeted treatments and cleansers with High fit levels for various skin types.

### Clinique or Hada Labo: which moisturizer is better?

Hada Labo provides better hydration and moisture with its moisturizers on this page compared to Clinique. Reviewers often mention Hada Labo for deep hydration and value, though some note sticky finishes.

### Which is more affordable, Clinique or Hada Labo?

Hada Labo offers better value and affordability compared to Clinique, as reviewers frequently highlight its good value.

### Which causes fewer breakouts, Clinique or Hada Labo?

Both Clinique and Hada Labo are equal in causing breakouts, as reviewers note occasional breakouts and clogged pores for both brands.

### How do the foundation years and parent companies of Clinique and Hada Labo compare?

Clinique was founded in 1968 in the United States and is owned by The Estée Lauder Companies Inc., whereas Hada Labo was founded in 2004 in Japan and is owned by Rohto Pharmaceutical Co., Ltd.

### Which brand offers better options for targeting dark spots and brightening the skin?

Clinique features a broader range of products on this page targeting dark spots with an Average to High Lovi fit across skin types, whereas Hada Labo focuses on deep hydration and brightening with popular options like the Shirojyun Premium Whitening Lotion.

### Do either of the brands include fragrance in their skincare product ingredients?

Both Clinique and Hada Labo do not include fragrance in their skincare product ingredients.

## Research behind their key ingredients

- [Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology](https://pubmed.ncbi.nlm.nih.gov/19169201/) Squalene · Molecules, 2009
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Micro-acid complex · Journal of Dermatological Science, 2017
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Protecting skin photoaging by NF-kappaB inhibitor](https://pubmed.ncbi.nlm.nih.gov/20540695/) Magnolia officinalis bark extract · Current Drug Metabolism, 2010
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf water, Aloe barbadensis · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramide · Scientific Reports, 2022
- [Preparation and characterization of a lecithin nanoemulsion as a topical delivery system](https://pubmed.ncbi.nlm.nih.gov/20652152/) Hydroxylated lecithin · Nanoscale Research Letters, 2009
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Effect of 30% Supramolecular Salicylic Acid Peel on Skin Microbiota and Inflammation in Patients with Moderate-to-Severe Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/36350527/) Micro-acid complex · Dermatology and Therapy, 2023
- [Systematic Study of Resveratrol Nanoliposomes Transdermal Delivery System for Enhancing Anti-Aging and Skin-Brightening Efficacy](https://pubmed.ncbi.nlm.nih.gov/36985709/) Polygonum cuspidatum root extract · Molecules, 2023
- [Role of Resveratrol in Regulating Cutaneous Functions](https://pubmed.ncbi.nlm.nih.gov/32382280/) Polygonum cuspidatum root extract · Evidence-based Complementary and Alternative Medicine, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB](https://pubmed.ncbi.nlm.nih.gov/17346696/) Magnolia officinalis bark extract · European Journal of Pharmacology, 2007
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results](https://pubmed.ncbi.nlm.nih.gov/39810881/) Probiotic technology · Journal of Experimental Pharmacology, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid, Micro-acid complex · Journal of Cosmetic Dermatology, 2024
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Encapsulation of alpha arbutin, a depigmenting agent, in nanosized ethosomes: Invitro and invivo human studies](https://pubmed.ncbi.nlm.nih.gov/37681127/) Alpha-arbutin · Heliyon, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin](https://pubmed.ncbi.nlm.nih.gov/22236139/) Magnesium ascorbyl phosphate · Photochemistry and Photobiology, 2012
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel extract · Journal of Cosmetic Science, 2018
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [The anti-wrinkles properties of sodium acetylated hyaluronate](https://pubmed.ncbi.nlm.nih.gov/34708918/) Sodium acetylhyaluronate · Journal of Cosmetic Dermatology, 2022
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Dimethoxytolyl propylresorcinol · Journal of Cosmetic Dermatology, 2021
- [Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits](https://pubmed.ncbi.nlm.nih.gov/20618556/) Multi-peptides · Journal of Cosmetic Dermatology, 2010
- [Algae extract protection effect on oxidized protein level in human stratum corneum](https://pubmed.ncbi.nlm.nih.gov/15247018/) Algae extract · Annals of the New York Academy of Sciences, 2004
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Amended safety assessment of Sesamum indicum (sesame) seed oil, hydrogenated sesame seed oil, Sesamum indicum (sesame) oil unsaponifiables, and sodium sesameseedate](https://pubmed.ncbi.nlm.nih.gov/21772026/) Sesamum indicum oil · International Journal of Toxicology, 2011
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Comparative Study on Epidermal Moisturizing Effects and Hydration Mechanisms of Rice-Derived Glucosylceramides and Ceramides](https://pubmed.ncbi.nlm.nih.gov/36613524/) Glucosyl ceramide · International Journal of Molecular Sciences, 2022
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride, Capric triglyceride · Life, 2023
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Effects of a Postbiotic Saccharomyces and Lactobacillus Ferment Complex on the Scalp Microbiome of Chinese Women with Sensitive Scalp Syndrome](https://pubmed.ncbi.nlm.nih.gov/37767337/) Lactobacillus ferment · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 3-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies](https://pubmed.ncbi.nlm.nih.gov/41668671/) Laminaria digitata extract · International Journal of Cosmetic Science, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter, Shea butter · Lasers in Medical Science, 2025
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Simmondsia chinensis (jojoba) cake fermentation: A new, sustainable technology for advanced skin and scalp care ingredients](https://pubmed.ncbi.nlm.nih.gov/42698229/) Lactobacillus ferment · International Journal of Cosmetic Science, 2026
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Combined Effect of Silybin and Sodium Acetylated Hyaluronate on UV-Induced Photoaging](https://pubmed.ncbi.nlm.nih.gov/42728863/) Sodium acetylhyaluronate · Skin Research and Technology, 2026

## The brands

- American skincare: [Clinique](https://lovi.care/skincare/ca/brands/clinique)
- Japanese skincare: [Hada Labo](https://lovi.care/skincare/ca/brands/hada-labo)

## More comparisons

- [SKIN1004 vs Clinique](https://lovi.care/skincare/ca/compare/skin1004-vs-clinique)
- [SKIN1004 vs Hada Labo](https://lovi.care/skincare/ca/compare/skin1004-vs-hada-labo)
- [Anua vs Clinique](https://lovi.care/skincare/ca/compare/anua-vs-clinique)
- [Anua vs Hada Labo](https://lovi.care/skincare/ca/compare/anua-vs-hada-labo)
- [Medicube vs Clinique](https://lovi.care/skincare/ca/compare/medicube-vs-clinique)
- [Medicube vs Hada Labo](https://lovi.care/skincare/ca/compare/medicube-vs-hada-labo)
- [The Ordinary vs Clinique](https://lovi.care/skincare/ca/compare/the-ordinary-vs-clinique)
- [The Ordinary vs Hada Labo](https://lovi.care/skincare/ca/compare/the-ordinary-vs-hada-labo)
- [Beauty of Joseon vs Clinique](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-clinique)
- [Beauty of Joseon vs Hada Labo](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-hada-labo)
- [COSRX vs Clinique](https://lovi.care/skincare/ca/compare/cosrx-vs-clinique)
- [COSRX vs Hada Labo](https://lovi.care/skincare/ca/compare/cosrx-vs-hada-labo)
- [CeraVe vs Clinique](https://lovi.care/skincare/ca/compare/cerave-vs-clinique)
- [CeraVe vs Hada Labo](https://lovi.care/skincare/ca/compare/cerave-vs-hada-labo)
- [La Roche-Posay vs Clinique](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-clinique)
- [La Roche-Posay vs Hada Labo](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-hada-labo)
- [Dr. Althea vs Clinique](https://lovi.care/skincare/ca/compare/dr-althea-vs-clinique)
- [Dr. Althea vs Hada Labo](https://lovi.care/skincare/ca/compare/dr-althea-vs-hada-labo)
- [Some By Mi vs Clinique](https://lovi.care/skincare/ca/compare/some-by-mi-vs-clinique)
- [Some By Mi vs Hada Labo](https://lovi.care/skincare/ca/compare/some-by-mi-vs-hada-labo)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/clinique-vs-hada-labo
- United Kingdom: https://lovi.care/skincare/uk/compare/clinique-vs-hada-labo
- Ireland: https://lovi.care/skincare/ie/compare/clinique-vs-hada-labo
- Germany: https://lovi.care/skincare/de/compare/clinique-vs-hada-labo
- France: https://lovi.care/skincare/fr/compare/clinique-vs-hada-labo
- Italy: https://lovi.care/skincare/it/compare/clinique-vs-hada-labo
- Netherlands: https://lovi.care/skincare/nl/compare/clinique-vs-hada-labo
- Spain: https://lovi.care/skincare/es/compare/clinique-vs-hada-labo
- Canada: https://lovi.care/skincare/ca/compare/clinique-vs-hada-labo (this page)
- Australia: https://lovi.care/skincare/au/compare/clinique-vs-hada-labo
- Singapore: https://lovi.care/skincare/sg/compare/clinique-vs-hada-labo
- Saudi Arabia: https://lovi.care/skincare/sa/compare/clinique-vs-hada-labo
- United Arab Emirates: https://lovi.care/skincare/ae/compare/clinique-vs-hada-labo