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Chamomile extracts · International Journal of Molecular Medicine, 2016Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter
Titanium dioxide · International Journal of Cosmetic Science, 2000Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Squalane · Scientific Reports, 2020Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
Aloe barbadensis leaf extract · Clinical Pharmacology, 2018Use of Collagen in Cosmetic Products
Water-soluble collagen · Current Issues in Molecular Biology, 2024Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study
Ascorbic acid · Clinical Oral Investigations, 2021Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin
Xylitol · Acta Dermato-venereologica, 2017Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation
Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020Injectable thermo-sensitive and wide-crack self-healing hydrogel loaded with antibacterial anti-inflammatory dipotassium glycyrrhizate for full-thickness skin wound repair
Dipotassium glycyrrhizate · Acta Biomaterialia, 2022Anti-inflammatory activities of colloidal oatmeal (Avena sativa) contribute to the effectiveness of oats in treatment of itch associated with dry, irritated skin
Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2015Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls
Camellia sinensis leaf extract · Experimental Dermatology, 2009The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide · Journal of Cosmetic Dermatology, 2021The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide
Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging-A split-face comparative study
Acerola fruit extract · Dermatologic Therapy, 2022A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
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Niacinamide · Scientific Reports, 2024Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation
Tocopheryl acetate · Urologia Internationalis, 2019Mechanism of action and clinical benefits of colloidal oatmeal for dermatologic practice
Avena sativa kernel extract · Journal of Drugs in Dermatology, 2010High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin
Witch hazel leaf extract · Phytochemistry, 2001Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects
Vitamin e · Journal of Cosmetic Dermatology, 2020Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach
Zinc oxide · Journal of Controlled Release, 2025Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study
Jojoba seed oil · Forschende Komplementarmedizin, 2012Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol
Hexylresorcinol · Journal of Drugs in Dermatology, 2016Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity
Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2016Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide
Hexylresorcinol · International Journal of Cosmetic Science, 2022Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs
Vitamin e · Journal of Cosmetic Dermatology, 2022Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model
Jojoba seed oil · Frontiers in Pharmacology, 2024Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations
Vitamin e · Journal of Cosmetic Dermatology, 2022In Vitro and Clinical Safety Assessment of the Multiple W/O/W Emulsion Based on the Active Ingredients from Rosmarinus officinalis L., Avena sativa L. and Linum usitatissimum L
Avena sativa kernel extract oat kernel extract · Pharmaceutics, 2021Whitening effect of alpha-bisabolol in Asian women subjects
Bisabolol · International Journal of Cosmetic Science, 2010Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract
Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019In Vitro and Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Efficacy and Safety of Nine Antiacne Medicinal Plants
Saponaria officinalis leaf extract · Evidence-based Complementary and Alternative Medicine, 2020Skin improvement and stability of Echinacea purpurea dermatological formulations
Echinacea purpurea extract · International Journal of Cosmetic Science, 2010In vivo and in vitro evaluation of octyl methoxycinnamate liposomes
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Squalane · Molecules, 2025The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome
Sodium lauroyl sarcosinate · Journal of Cosmetic Dermatology, 2024Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration
Betaine · Molecules, 2024Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid
Betaine · Pharmaceutics, 2024Influence of vitamin E acetate on stratum corneum hydration
Tocopheryl acetate · Arzneimittel-Forschung, 1998Nanowire-based squalene oleogel repairs skin photoaging
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Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment
Moringa oleifera seed extract · Polymers, 2022Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence
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Panthenol · Journal of Cosmetic Dermatology, 2025Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance
Hexylresorcinol · Archives of Dermatological Research, 2023Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study
Saffron extracts flower · Journal of Clinical Medicine, 2022Moisturizing effect of stable cream containing Crocus sativus extracts
Saffron extracts flower · Pakistan Journal of Pharmaceutical Sciences, 2014Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin
Vitamin e · Journal of Cosmetic Dermatology, 2024Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy
Tocopheryl acetate · Scientific Reports, 2025Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum
Caprylic capric triglyceride · Life, 2023Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study
Jojoba esters · Journal of Cosmetic Dermatology, 2008A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females
Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016In vitro, ex vivo and clinical approaches to evaluate the potential effect of Gentiana lutea extract on skin
Gentiana lutea extract · International Journal of Cosmetic Science, 2023Lemon Balm (Melissa officinalis L.) Leaf Extract Promotes Endo180 Production in Dermal Fibroblasts and has Antiwrinkle Effect on Human Skin
Melissa officinalis leaf extract · Photodermatology, Photoimmunology & Photomedicine, 2025Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial
Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021Topical application of retinyl propionate, 4 hexyl resorcinol, and niacinamide reverses molecular and clinical features of ageing
Hexylresorcinol · International Journal of Cosmetic Science, 2024Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Ascorbyl glucoside · International Journal of Molecular Sciences, 2024Cleansing lotion containing tamarind fruit pulp extract. II. Study of cumulative irritation effects in human
Tamarindus indica pulp · Journal of Cosmetic Dermatology, 2007Facial disbiosis and UV filters
Ethylhexyl methoxycinnamate · Archives of Dermatological Research, 2024Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin
Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025Microcirculation-Promoting Effect of Escin on Cutaneous Tissue via Gsk3β Down-Regulation
Escin · Current Issues in Molecular Biology, 2025Microcirculatory efficacy of topical treatment with aescin + essential phospholipids gel in venous insufficiency and hypertension: new clinical observations
Escin · Angiology, 2004Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial
Butyrospermum parkii butter shea butter, Saccharide isomerate, Shea butter · Lasers in Medical Science, 2025Phytochemical characterization and antidermatophytic activity of a leaf extract from Mitracarpusscaber
Mitracarpus scaber extract · Journal of Ethnopharmacology, 2026A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study
Saccharide isomerate · The Journal of Dermatological Treatment, 2025Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
Saccharide isomerate · Journal of Cosmetic Dermatology, 2023Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial
Ascorbyl glucoside · Cureus, 2026Two new lipoaminoacids with complementary modes of action: new prospects to fight out against skin aging
Palmitoyl glycine · International Journal of Cosmetic Science, 2010Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial
Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
