# Avène vs Simple

Page: https://lovi.care/skincare/ca/compare/avene-vs-simple

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Canada.

Avène and Simple are two renowned skincare labels offering gentle moisturizers, soothing cleansers, and reliable formulations designed to support healthy complexions. The French brand relies on [glycerin](https://lovi.care/skincare/ca/ingredients/glycerin) to nurture oily, acne-prone, and combination skin through targeted [serums](https://lovi.care/skincare/ca/ingredients/serum), protective sunscreens, and rich recovery balms. Meanwhile, the British counterpart utilizes [niacinamide](https://lovi.care/skincare/ca/ingredients/niacinamide) and glycerin in refreshing toners and dependable makeup removers to address oily and mature skin concerns. While both options strengthen the skin barrier and boost hydration, they differ in their specific ingredient profiles, regional heritage, and specialized product offerings.

Avène is a French skincare brand founded in 1990 and owned by Fondation Pierre Fabre.

[pierre-fabre.com](https://www.pierre-fabre.com/en/our-company/governance) [avene.co.uk](https://www.avene.co.uk/a/water-that-makes-all-the-difference-thermal-spring-water) [aveneusa.com](https://www.aveneusa.com/history)

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Simple_Skincare) [sec.gov](https://www.sec.gov/Archives/edgar/data/1368457/000119312511134453/dex991.htm) [prnewswire.com](https://www.prnewswire.com/news-releases/alberto-culver-announces-that-unilever-has-received-approval-from-the-us-department-of-justice-to-complete-the-acquisition-of-the-company-121400884.html) [simple.co.uk](https://www.simple.co.uk/philosophy.html)

This page compares some of the most popular Avène and Simple products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgf70b534491).

### Popular Avène vs Simple products

#### Avène

- [Cicalfate+ Restorative Protective Cream](https://lovi.care/skincare/ca/p/avene/cicalfate-restorative-protective-cream/for/dry-skin) — High fit — [CA$26.90 at Amazon](https://www.amazon.ca/dp/B0C47GMR68?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Cleanance](https://lovi.care/skincare/ca/p/avene/cleanance/for/oily-skin) — Superior fit — [CA$33.99 at Amazon](https://www.amazon.ca/dp/B0GF9YT1Z3?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Cleanance Cleansing Gel](https://lovi.care/skincare/ca/p/avene/cleanance-cleansing-gel/for/oily-acne-prone-skin) — High fit — [CA$31.49 at Amazon](https://www.amazon.ca/dp/B01MQWXZNV?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Hydrance+](https://lovi.care/skincare/ca/p/avene/hydrance/for/dry-sensitive-skin) — Average fit
- [Tolerance Control Soothing Skin Recovery Balm](https://lovi.care/skincare/ca/p/avene/tolerance-control-soothing-skin-recovery-balm/for/dry-skin) — Superior fit — [CA$43.99 at Amazon](https://www.amazon.ca/dp/B08XYVMRP7?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [RetrinAL EYES](https://lovi.care/skincare/ca/p/avene/retrinal-eyes/for/dry-skin) — High fit
- [Cold Cream](https://lovi.care/skincare/ca/p/avene/cold-cream/for/dry-sensitive-skin) — High fit
- [Vitamin Activ Cg Radiance Concentrated Serum](https://lovi.care/skincare/ca/p/avene/vitamin-activ-cg-radiance-concentrated-serum/for/mature-skin) — High fit — [CA$77.00 at Amazon](https://www.amazon.ca/dp/B0CPYN8FVC?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)

#### Simple

- [Micellar Water](https://lovi.care/skincare/ca/p/simple/micellar-water/for/mature-skin) — Average fit — [CA$11.99 at Amazon](https://www.amazon.ca/dp/B0GQQSFPG9?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Micellar Cleansing Water](https://lovi.care/skincare/ca/p/simple/micellar-cleansing-water/for/sensitive-skin) — High fit — [CA$11.99 at Amazon](https://www.amazon.ca/dp/B0GQQSFPG9?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Hydrating Light Moisturiser](https://lovi.care/skincare/ca/p/simple/hydrating-light-moisturiser/for/dry-skin) — Average fit — [CA$15.88 at Amazon](https://www.amazon.ca/dp/B000LQX6XG?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Refreshing Facial Wash](https://lovi.care/skincare/ca/p/simple/refreshing-facial-wash/for/acne-prone-skin) — Average fit — [CA$12.79 at Amazon](https://www.amazon.ca/dp/B000LQUA6M?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Replenishing Rich Moisturiser](https://lovi.care/skincare/ca/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [CA$13.40 at Amazon](https://www.amazon.ca/dp/B000LNHB6M?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)
- [Water Boost Hydrating Gel Cream](https://lovi.care/skincare/ca/p/simple/water-boost-hydrating-gel-cream/for/dry-skin) — Average fit
- [Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/ca/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — [CA$18.72 at Amazon](https://www.amazon.ca/dp/B076V2D94Y?tag=lovi-care-web-product01-20&linkCode=osi&th=1&psc=1)

## People Say

Avène

Simple

- Soothes and calms sensitive skin Mostly Mentioned Mostly Mentioned “Does not cause any form of irritation on the skin which I love. — Simple Micellar Cleansing Water” “The only cleanser that doesn't turn my face red. — Simple Micellar Water” “no artificial perfume — Simple Hydrating Light Moisturiser” “Calmed my angry red skin overnight — Avène Cicalfate+ Restorative Protective Cream”
- Rich texture and deep hydration Often Mentioned Mostly Mentioned “banished dryness within days — Simple Replenishing Rich Moisturiser” “sinks in instantly — Simple Water Boost Hydrating Gel Cream” “Instantly boosts skin's hydration... face doesn't feel dry and tight. — Simple Micellar Cleansing Water” “Thick but absorbs well eventually — Avène Cicalfate+ Restorative Protective Cream”
- Improves overall skin texture and radiance Sometimes Noted Often Mentioned “sinks in instantly — Simple Water Boost Hydrating Gel Cream” “absorbs very quickly — Simple Hydrating Light Moisturiser” “love that it's alcohol-free — Simple Kind to Skin Soothing Facial Toner” “immediate radiance boost — Avène Vitamin Activ Cg Radiance Concentrated Serum”
- Gentle and non-stripping cleansers Sometimes Noted Often Mentioned “Takes off any makeup residue and makes my face feel refreshed. — Simple Micellar Cleansing Water” “Best morning cleanser — Simple Refreshing Facial Wash” “Skin feels soft not dry — Simple Refreshing Facial Wash” “leaves face clean but not dry — Avène Cleanance”
- Price point and value Rarely Noted Often Mentioned “great value for money — Simple Kind to Skin Soothing Facial Toner” “super affordable — Simple Hydrating Light Moisturiser” “Can't beat the price for the quality. — Simple Micellar Water” “Bottle lasts for months — Avène Cleanance Cleansing Gel”
- Repairs and protects skin barrier Often Mentioned Not noted “Saves my skin in winter — Avène Cold Cream” “Healed my over-exfoliated skin in days — Avène Cicalfate+ Restorative Protective Cream” “This repairs my skin barrier without fail. — Avène Tolerance Control Soothing Skin Recovery Balm”
- Formula changes and product issues Sometimes Noted Often Mentioned “bring it back — Avène Antirougeurs Fort Relief Concentrate” “They have changed the formula recently, and it... is not as good. — Avène Milk Cleanser” “It absolutely couldn't remove anything on its own. — Avène Milk Cleanser” “Did not remove my mascara very well at all. — Simple Micellar Cleansing Water”
- Causes breakouts and skin reactions Sometimes Noted Sometimes Noted “Woke up with tiny whiteheads all over — Avène Cicalfate+ Restorative Protective Cream” “Caused small bumps/texture — Avène Soothing Radiance Mask” “Gave me tiny bumps on my forehead. — Simple Micellar Water” “caused major breakouts — Simple Hydrating Light Moisturiser”
- Thick or greasy residue Sometimes Noted Sometimes Noted “Leaves a greasy film — Avène Cold Cream” “too thick — Avène Hydrance+” “Feels slimy on skin — Simple Refreshing Facial Wash” “Still feeling a little bit of a film on my skin. — Simple Micellar Cleansing Water”

### Avène vs Simple routines for dry skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/ca/p/simple/refreshing-facial-wash/for/dry-skin) — Low fit — [CA$12.79 at Amazon](https://www.amazon.ca/dp/B000LQUA6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/ca/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [CA$27.99 at Amazon](https://www.amazon.ca/dp/B07B65NJLV?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/ca/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [CA$13.40 at Amazon](https://www.amazon.ca/dp/B000LNHB6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/ca/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [CA$38.00 at Amazon](https://www.amazon.ca/dp/B091T7JKQJ?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/ca/p/simple/micellar-cleansing-water/for/dry-skin) — High fit — [CA$11.99 at Amazon](https://www.amazon.ca/dp/B0GQQSFPG9?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [SKIN1004 Madagascar Centella Poremizing Fresh Ampoule](https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-poremizing-fresh-ampoule/for/dry-skin) — Superior fit — [CA$22.09 at Amazon](https://www.amazon.ca/dp/B0B1JRGGLF?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/ca/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [CA$29.99 at Amazon](https://www.amazon.ca/dp/B09XWPL5VN?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

#### Avène-focused routine

- Cleanser: [Cleanance Cleansing Gel](https://lovi.care/skincare/ca/p/avene/cleanance-cleansing-gel/for/dry-skin) — Caution fit — [CA$31.49 at Amazon](https://www.amazon.ca/dp/B01MQWXZNV?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/ca/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [CA$27.99 at Amazon](https://www.amazon.ca/dp/B07B65NJLV?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Tolerance Control Soothing Skin Recovery Balm](https://lovi.care/skincare/ca/p/avene/tolerance-control-soothing-skin-recovery-balm/for/dry-skin) — Superior fit — [CA$43.99 at Amazon](https://www.amazon.ca/dp/B08XYVMRP7?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Ultra Fluid](https://lovi.care/skincare/ca/p/avene/ultra-fluid/for/dry-skin) — Low fit — [CA$37.40 at Amazon](https://www.amazon.ca/dp/B06XQ12G34?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/ca/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [CA$17.99 at Amazon](https://www.amazon.ca/dp/B084Q16G8D?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Vitamin Activ Cg Radiance Concentrated Serum](https://lovi.care/skincare/ca/p/avene/vitamin-activ-cg-radiance-concentrated-serum/for/dry-skin) — Average fit — [CA$77.00 at Amazon](https://www.amazon.ca/dp/B0CPYN8FVC?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/ca/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [CA$29.99 at Amazon](https://www.amazon.ca/dp/B09XWPL5VN?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Simple routine · CA$156.25 · 83% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B07B65NJLV&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B091T7JKQJ&Quantity.4=1&ASIN.5=B0GQQSFPG9&Quantity.5=1&ASIN.6=B0B1JRGGLF&Quantity.6=1&ASIN.7=B09XWPL5VN&Quantity.7=1&AssociateTag=lovi-care-web-routine0a-20) [Buy Avène routine · CA$265.85 · 76% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B01MQWXZNV&Quantity.1=1&ASIN.2=B07B65NJLV&Quantity.2=1&ASIN.3=B08XYVMRP7&Quantity.3=1&ASIN.4=B06XQ12G34&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B0CPYN8FVC&Quantity.6=1&ASIN.7=B09XWPL5VN&Quantity.7=1&AssociateTag=lovi-care-web-routine0a-20) [See multi-brand routine · 99% fit](https://lovi.care/skincare/ca/skin/dry-skin)

### Avène vs Simple routines for oily skin

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/ca/p/simple/refreshing-facial-wash/for/oily-skin) — Average fit — [CA$12.79 at Amazon](https://www.amazon.ca/dp/B000LQUA6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — [CA$37.60 at Amazon](https://www.amazon.ca/dp/B0CJMZB63M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/ca/p/simple/replenishing-rich-moisturiser/for/oily-skin) — Average fit — [CA$13.40 at Amazon](https://www.amazon.ca/dp/B000LNHB6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60](https://lovi.care/skincare/ca/p/la-roche-posay/anthelios-clear-skin-dry-touch-sunscreen-spf-60/for/oily-skin) — Superior fit — [CA$35.95 at Amazon](https://www.amazon.ca/dp/B08CHZPRRB?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/ca/p/simple/micellar-cleansing-water/for/oily-skin) — High fit — [CA$11.99 at Amazon](https://www.amazon.ca/dp/B0GQQSFPG9?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/ca/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [CA$28.90 at Amazon](https://www.amazon.ca/dp/B09SN5B88W?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [The Ordinary Niacinamide 10% + Zinc 1%](https://lovi.care/skincare/ca/p/the-ordinary/niacinamide-10-zinc-1/for/oily-skin) — Superior fit — [CA$6.60 at Amazon](https://www.amazon.ca/dp/B01MDTVZTZ?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Tatcha The Clarifying Clay Mask](https://lovi.care/skincare/ca/p/tatcha/the-clarifying-clay-mask/for/oily-skin) — Superior fit — [CA$95.00 at Amazon](https://www.amazon.ca/dp/B09VCP4J1N?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

#### Avène-focused routine

- Cleanser: [Cleanance Cleansing Gel](https://lovi.care/skincare/ca/p/avene/cleanance-cleansing-gel/for/oily-skin) — High fit — [CA$31.49 at Amazon](https://www.amazon.ca/dp/B01MQWXZNV?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — [CA$37.60 at Amazon](https://www.amazon.ca/dp/B0CJMZB63M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Cicalfate+ Restorative Protective Cream](https://lovi.care/skincare/ca/p/avene/cicalfate-restorative-protective-cream/for/oily-skin) — Low fit — [CA$26.90 at Amazon](https://www.amazon.ca/dp/B0C47GMR68?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Cleanance](https://lovi.care/skincare/ca/p/avene/cleanance/for/oily-skin) — Superior fit — [CA$33.99 at Amazon](https://www.amazon.ca/dp/B0GF9YT1Z3?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/ca/p/pyunkang-yul/deep-cleansing-oil/for/oily-skin) — Superior fit — [CA$23.99 at Amazon](https://www.amazon.ca/dp/B08QTT1QBX?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/ca/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [CA$28.90 at Amazon](https://www.amazon.ca/dp/B09SN5B88W?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Tatcha The Clarifying Clay Mask](https://lovi.care/skincare/ca/p/tatcha/the-clarifying-clay-mask/for/oily-skin) — Superior fit — [CA$95.00 at Amazon](https://www.amazon.ca/dp/B09VCP4J1N?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Simple routine · CA$271.73 · 87% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B0CJMZB63M&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B08CHZPRRB&Quantity.4=1&ASIN.5=B0GQQSFPG9&Quantity.5=1&ASIN.6=B09SN5B88W&Quantity.6=1&ASIN.7=B01MDTVZTZ&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09VCP4J1N&Quantity.9=1&AssociateTag=lovi-care-web-routine0a-20) [Buy Avène routine · CA$307.37 · 86% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B01MQWXZNV&Quantity.1=1&ASIN.2=B0CJMZB63M&Quantity.2=1&ASIN.3=B0C47GMR68&Quantity.3=1&ASIN.4=B0GF9YT1Z3&Quantity.4=1&ASIN.5=B08QTT1QBX&Quantity.5=1&ASIN.6=B09SN5B88W&Quantity.6=1&ASIN.7=B001VMJSCW&Quantity.7=1&ASIN.8=B09VCP4J1N&Quantity.8=1&AssociateTag=lovi-care-web-routine0a-20) [See multi-brand routine · 96% fit](https://lovi.care/skincare/ca/skin/oily-skin)

### Avène vs Simple routines for combination skin

#### Avène-focused routine

- Cleanser: [Cleanance Cleansing Gel](https://lovi.care/skincare/ca/p/avene/cleanance-cleansing-gel/for/combination-skin) — Average fit — [CA$31.49 at Amazon](https://www.amazon.ca/dp/B01MQWXZNV?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [CA$37.60 at Amazon](https://www.amazon.ca/dp/B0CJMZB63M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hyaluron Activ B3 Concentrated Plumping Serum](https://lovi.care/skincare/ca/p/avene/hyaluron-activ-b3-concentrated-plumping-serum/for/combination-skin) — High fit — [CA$77.99 at Amazon](https://www.amazon.ca/dp/B0BS9Y6F96?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Cleanance](https://lovi.care/skincare/ca/p/avene/cleanance/for/combination-skin) — High fit — [CA$33.99 at Amazon](https://www.amazon.ca/dp/B0GF9YT1Z3?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/ca/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — [CA$23.99 at Amazon](https://www.amazon.ca/dp/B08QTT1QBX?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/ca/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [CA$31.99 at Amazon](https://www.amazon.ca/dp/B0CVRCR6VF?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Vitamin Activ Cg Radiance Concentrated Serum](https://lovi.care/skincare/ca/p/avene/vitamin-activ-cg-radiance-concentrated-serum/for/combination-skin) — Average fit — [CA$77.00 at Amazon](https://www.amazon.ca/dp/B0CPYN8FVC?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Origins Original Skin Retexturizing Mask with Rose Clay](https://lovi.care/skincare/ca/p/origins/original-skin-retexturizing-mask-with-rose-clay/for/combination-skin) — Superior fit — [CA$50.00 at Amazon](https://www.amazon.ca/dp/B0DV8YNCC5?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/ca/p/simple/refreshing-facial-wash/for/combination-skin) — Average fit — [CA$12.79 at Amazon](https://www.amazon.ca/dp/B000LQUA6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/ca/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [CA$37.60 at Amazon](https://www.amazon.ca/dp/B0CJMZB63M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/ca/p/simple/replenishing-rich-moisturiser/for/combination-skin) — Average fit — [CA$13.40 at Amazon](https://www.amazon.ca/dp/B000LNHB6M?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/ca/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [CA$20.96 at Amazon](https://www.amazon.ca/dp/B083GGPQ8C?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/ca/p/simple/micellar-cleansing-water/for/combination-skin) — Average fit — [CA$11.99 at Amazon](https://www.amazon.ca/dp/B0GQQSFPG9?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/ca/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [CA$31.99 at Amazon](https://www.amazon.ca/dp/B0CVRCR6VF?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [The Ordinary Niacinamide 10% + Zinc 1%](https://lovi.care/skincare/ca/p/the-ordinary/niacinamide-10-zinc-1/for/combination-skin) — Superior fit — [CA$6.60 at Amazon](https://www.amazon.ca/dp/B01MDTVZTZ?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/ca/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [CA$29.50 at Amazon](https://www.amazon.ca/dp/B001VMJSCW?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Origins Original Skin Retexturizing Mask with Rose Clay](https://lovi.care/skincare/ca/p/origins/original-skin-retexturizing-mask-with-rose-clay/for/combination-skin) — Superior fit — [CA$50.00 at Amazon](https://www.amazon.ca/dp/B0DV8YNCC5?tag=lovi-care-web-routine0a-20&linkCode=osi&th=1&psc=1) — Once a week

[Buy Avène routine · CA$393.55 · 88% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B01MQWXZNV&Quantity.1=1&ASIN.2=B0CJMZB63M&Quantity.2=1&ASIN.3=B0BS9Y6F96&Quantity.3=1&ASIN.4=B0GF9YT1Z3&Quantity.4=1&ASIN.5=B08QTT1QBX&Quantity.5=1&ASIN.6=B0CVRCR6VF&Quantity.6=1&ASIN.7=B0CPYN8FVC&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B0DV8YNCC5&Quantity.9=1&AssociateTag=lovi-care-web-routine0a-20) [Buy Simple routine · CA$214.83 · 86% fit](https://www.amazon.ca/gp/aws/cart/add.html?ASIN.1=B000LQUA6M&Quantity.1=1&ASIN.2=B0CJMZB63M&Quantity.2=1&ASIN.3=B000LNHB6M&Quantity.3=1&ASIN.4=B083GGPQ8C&Quantity.4=1&ASIN.5=B0GQQSFPG9&Quantity.5=1&ASIN.6=B0CVRCR6VF&Quantity.6=1&ASIN.7=B01MDTVZTZ&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B0DV8YNCC5&Quantity.9=1&AssociateTag=lovi-care-web-routine0a-20) [See multi-brand routine · 96% fit](https://lovi.care/skincare/ca/skin/combination-skin)

## Questions and answers

### Avène or Simple: which is better?

Both Avène and Simple are great choices, as they offer equal fit levels across almost all skin types. Simple tends to do better with soothing sensitive skin, providing deep hydration, and value, while Avène is known for repairing and protecting the skin barrier.

### What is the difference between Avène and Simple?

Simple stands out for being fragrance-free across the products on this page and better at soothing sensitive skin, while Avène is recognized for repairing and protecting the skin barrier. Lovi rates both brands with equal high routines for dry skin, oily skin, combination skin, sensitive skin, acne-prone skin, mature skin, skin with dark spots, and oily acne-prone skin, but Simple holds a high fit for dry sensitive skin compared to Avène's average.

### Avène or Simple for dry skin?

Both Avène and Simple are a great match for dry skin, with Lovi giving them an equal fit level. Avène uses [thermal water](https://lovi.care/skincare/ca/ingredients/thermal-water) and [glycerin](https://lovi.care/skincare/ca/ingredients/glycerin) to help soothe irritation, while Simple relies on [niacinamide](https://lovi.care/skincare/ca/ingredients/niacinamide) and glycerin to deliver lightweight hydration.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Avène or Simple: which cleanser is better?

Simple offers better cleansers on this page for sensitive skin types, while Avène is a better fit for oily and acne-prone skin. Simple provides gentle, sensitive-skin-friendly makeup removers, and Avène helps deliver a gentle deep clean.

### Which is more affordable, Avène or Simple?

Simple stands out for its price point and value, while Avène is sometimes noted in reviews for its price point. Review themes on the page also note that Simple offers better value.

### Which brand has more fragrance-free products, Avène or Simple?

Simple has more fragrance-free products than Avène, as every product on the Simple page lists no fragrance in its ingredients compared to only 7 of 15 products on the Avène page.

### Avène or Simple: which brand repairs and protects the skin barrier better?

Avène does better at repairing and protecting the skin barrier. Review themes show that Avène excels in this area compared to Simple.

### Avène or Simple for oily skin?

Both Avène and Simple fit oily skin at a High routine level. Avène features thermal water and glycerin, while Simple includes niacinamide and glycerin.

### Avène or Simple: which moisturizer is better?

Simple offers more value-friendly and lightweight moisturizers, whereas Avène helps soothe irritation and features options with a rich texture. Both brands provide moisturizers that are a High fit for dry skin on this page.

### Avène or Simple for sensitive skin?

Both Avène and Simple reach a High Lovi fit level for sensitive skin. Reviewers note that Simple does better at soothing and calming sensitive skin, while Avène also offers thermal water and glycerin across the products on this page.

### Avène or Simple for acne-prone skin?

Both Avène and Simple are a High fit for acne-prone skin on this page, and reviewers note that Avène helps soothe irritation while Simple is a value-friendly choice. Simple relies on ingredients like niacinamide and glycerin, and studies show niacinamide may help control skin aging and pigmentation.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Avène or Simple for dry sensitive skin?

Simple is a better choice for dry sensitive skin because Lovi rates its routine fit as High, whereas Avène is rated Average. Simple relies on key ingredients like niacinamide and glycerin to hydrate, and niacinamide may help improve overall skin texture.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Ascorbic acid activ cg · Experimental Dermatology, 2003
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol, Bakuchiol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019
- [Efficacy and tolerability assessment of a topical formulation containing copper sulfate and hypericum perforatum on patients with herpes skin lesions: a comparative, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/22270204/) Copper sulfate · Journal of Drugs in Dermatology, 2012
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [An oil-soluble extract of Rubus idaeus cells enhances hydration and water homeostasis in skin cells](https://pubmed.ncbi.nlm.nih.gov/25940647/) Rubus idaeus fruit extract raspberry fruit extract · International Journal of Cosmetic Science, 2015
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study](https://pubmed.ncbi.nlm.nih.gov/36698447/) Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023
- [A new dermocosmetic containing retinaldehyde, delta-tocopherol glucoside and glycylglycine oleamide for managing naturally aged skin: results from in vitro to clinical studies](https://pubmed.ncbi.nlm.nih.gov/28203099/) Tocopheryl glucoside · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Efficacy and safety of non-thermal nitrogen plasma versus long-pulsed Nd:YAG laser for hand rejuvenation](https://pubmed.ncbi.nlm.nih.gov/33420853/) Nitrogen · Lasers in Medical Science, 2022
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Comparative benefit of two thermal spring waters after photodynamic therapy procedure](https://pubmed.ncbi.nlm.nih.gov/17348993/) Avène thermal spring water, Avene thermal spring water avene aqua · Journal of Cosmetic Dermatology, 2007
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [Wax-oil lubricants to reduce the shear between skin and PPE](https://pubmed.ncbi.nlm.nih.gov/34078980/) Paraffinum liquidum mineral oil · Scientific Reports, 2021
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis seed oil · Lipids, 2020
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Specific protection of sensitive skin against environmental stress by maintenance and improvement of barrier function](https://pubmed.ncbi.nlm.nih.gov/35315151/) Aquaphilus dolomiae extract filtrate · Journal of the European Academy of Dermatology and Venereology, 2022
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Sustained effect of two antioxidants (oxothiazolidine and δ-tocopheryl glucoside) for immediate and long-term sun protection in a sunscreen emulsion based on their different penetrating properties](https://pubmed.ncbi.nlm.nih.gov/33848378/) Tocopheryl glucoside · International Journal of Cosmetic Science, 2021
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Clinical evaluation of anaesthetic-like effect of two dermocosmetic formulations containing Aquaphilus dolomiae extract-G3 in subjects with sensitive facial skin](https://pubmed.ncbi.nlm.nih.gov/35315150/) Aquaphilus dolomiae extract filtrate · Journal of the European Academy of Dermatology and Venereology, 2022
- [The Real-World Effectiveness and Tolerability of a Soothing Cream Containing the Postbiotic Aquaphilus dolomiae Extract-G2 for Skin Healing](https://pubmed.ncbi.nlm.nih.gov/38451421/) Aquaphilus dolomiae extract filtrate · Dermatology and Therapy, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/32870553/) Thermal spring water, Aqua dolomiae extract · Journal of the European Academy of Dermatology and Venereology, 2020
- [Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study](https://pubmed.ncbi.nlm.nih.gov/38553920/) Avène thermal spring water, Avene thermal spring water avene aqua, Thermal spring water · The Medical Journal of Malaysia, 2024
- [Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study](https://pubmed.ncbi.nlm.nih.gov/41487026/) Zinc gluconate · Journal of Cosmetic Dermatology, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [A cleanser formulated with Tris (hydroxymethyl) aminomethane and l-arginine significantly improves facial acne in male Thai subjects](https://pubmed.ncbi.nlm.nih.gov/31347768/) Arginine · Journal of Cosmetic Dermatology, 2020
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Saccharide isomerate · Lasers in Medical Science, 2025
- [Clinical Evaluation of a Soap-Free Cleansing Lotion Containing Sodium Cocoyl Apple Amino Acids for Effective Impurity Removal and Skin Barrier Preservation in Healthy Adults With Diverse Skin Types](https://pubmed.ncbi.nlm.nih.gov/40978887/) Cetyl alcohol · Cureus, 2025
- [Dermatological Effects of a Beeswax-Pine Resin Mixture on Abdominal Skin: A Proof-of-Concept Study Supporting the Development of an Affordable Investigational Ostomy Pouching System in Low-Income Regions](https://pubmed.ncbi.nlm.nih.gov/42758164/) Beeswax cera alba cera · Journal of Wound, Ostomy, and Continence Nursing, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population](https://pubmed.ncbi.nlm.nih.gov/35279940/) Saccharide isomerate · Journal of Cosmetic Dermatology, 2023

## The brands

- French skincare: [Avène](https://lovi.care/skincare/ca/brands/avene)
- British skincare: [Simple](https://lovi.care/skincare/ca/brands/simple)

## More comparisons

- [SKIN1004 vs Avène](https://lovi.care/skincare/ca/compare/skin1004-vs-avene)
- [SKIN1004 vs Simple](https://lovi.care/skincare/ca/compare/skin1004-vs-simple)
- [Anua vs Avène](https://lovi.care/skincare/ca/compare/anua-vs-avene)
- [Anua vs Simple](https://lovi.care/skincare/ca/compare/anua-vs-simple)
- [Medicube vs Avène](https://lovi.care/skincare/ca/compare/medicube-vs-avene)
- [Medicube vs Simple](https://lovi.care/skincare/ca/compare/medicube-vs-simple)
- [The Ordinary vs Avène](https://lovi.care/skincare/ca/compare/the-ordinary-vs-avene)
- [The Ordinary vs Simple](https://lovi.care/skincare/ca/compare/the-ordinary-vs-simple)
- [Beauty of Joseon vs Avène](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-avene)
- [Beauty of Joseon vs Simple](https://lovi.care/skincare/ca/compare/beauty-of-joseon-vs-simple)
- [COSRX vs Avène](https://lovi.care/skincare/ca/compare/cosrx-vs-avene)
- [COSRX vs Simple](https://lovi.care/skincare/ca/compare/cosrx-vs-simple)
- [CeraVe vs Avène](https://lovi.care/skincare/ca/compare/cerave-vs-avene)
- [CeraVe vs Simple](https://lovi.care/skincare/ca/compare/cerave-vs-simple)
- [La Roche-Posay vs Avène](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-avene)
- [La Roche-Posay vs Simple](https://lovi.care/skincare/ca/compare/la-roche-posay-vs-simple)
- [Dr. Althea vs Avène](https://lovi.care/skincare/ca/compare/dr-althea-vs-avene)
- [Dr. Althea vs Simple](https://lovi.care/skincare/ca/compare/dr-althea-vs-simple)
- [Some By Mi vs Avène](https://lovi.care/skincare/ca/compare/some-by-mi-vs-avene)
- [Some By Mi vs Simple](https://lovi.care/skincare/ca/compare/some-by-mi-vs-simple)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/avene-vs-simple
- United Kingdom: https://lovi.care/skincare/uk/compare/avene-vs-simple
- Ireland: https://lovi.care/skincare/ie/compare/avene-vs-simple
- Germany: https://lovi.care/skincare/de/compare/avene-vs-simple
- France: https://lovi.care/skincare/fr/compare/avene-vs-simple
- Italy: https://lovi.care/skincare/it/compare/avene-vs-simple
- Netherlands: https://lovi.care/skincare/nl/compare/avene-vs-simple
- Spain: https://lovi.care/skincare/es/compare/avene-vs-simple
- Canada: https://lovi.care/skincare/ca/compare/avene-vs-simple (this page)
- Australia: https://lovi.care/skincare/au/compare/avene-vs-simple
- Singapore: https://lovi.care/skincare/sg/compare/avene-vs-simple
- Saudi Arabia: https://lovi.care/skincare/sa/compare/avene-vs-simple
- United Arab Emirates: https://lovi.care/skincare/ae/compare/avene-vs-simple