# Advanced Clinicals skincare

Page: https://lovi.care/skincare/brands/advanced-clinicals

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Advanced Clinicals is an American skincare brand founded in 2005 and owned by Concept Laboratories, Inc..

[tracxn.com](https://tracxn.com/d/companies/advanced-clinicals/__5SAKCpIAzQ6c5NRt4-PNS8xWIapHacc9Q2SepTdbIfM)

Advanced Clinicals is loved for its moisturizers, [serums](https://lovi.care/skincare/ingredients/serum), and targeted formulas. Its products suit oily skin and acne-prone skin best. The standout products for particular concerns include the [Vitamin C](https://lovi.care/skincare/ingredients/vitamin-c) Brightening Gel-Cream for acne-prone skin, the Vitamin C Anti Aging Serum for skin with dark spots, and the [Retinol](https://lovi.care/skincare/ingredients/retinol) Advanced Firming Cream for mature skin. The brand consistently delivers thoughtful, effective care for daily routines.

This page covers some of the most popular Advanced Clinicals products; for the whole Advanced Clinicals range, with a fit score for every product, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=brand&af_sub3=selection_note&af_sub4=pgea1ba3d0ba).

### Other Advanced Clinicals products

#### Other products

- [Retinol Advanced Firming Cream](https://lovi.care/skincare/p/advanced-clinicals/retinol-advanced-firming-cream/for/mature-skin) — Average fit
- [Vitamin C Anti Aging Serum](https://lovi.care/skincare/p/advanced-clinicals/vitamin-c-anti-aging-serum/for/combination-skin) — Average fit — [$9.46 at Amazon](https://www.amazon.com/dp/B013RJ8804?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
- [Collagen Skin Rescue Lotion](https://lovi.care/skincare/p/advanced-clinicals/collagen-skin-rescue-lotion/for/dry-skin) — Average fit
- [HYALURONIC SERUM](https://lovi.care/skincare/p/advanced-clinicals/hyaluronic-serum/for/acne-prone-skin) — Average fit
- [Vitamin C Brightening Gel-Cream](https://lovi.care/skincare/p/advanced-clinicals/vitamin-c-brightening-gel-cream/for/mature-skin) — High fit

## People Say

★4.6

Overall rating based on 232.7k+ reviews

Reviewers most often praise Advanced Clinicals for enhancing skin texture, deep hydration, and diminishing fine lines. The most common complaints are a drying or dehydrating effect and a slightly sticky finish.

### Highlights

- Great value Mostly Mentioned “huge bottle for the price — Vitamin C Anti Aging Serum” “Amazing quality for the price — Retinol Advanced Firming Cream” “Great value for the size — Collagen Skin Rescue Lotion”
- Improved skin texture and tone Mostly Mentioned “noticeably lightened age spots — Vitamin C Anti Aging Serum” “My skin feels firmer, smoother, and well-hydrated — Retinol Advanced Firming Cream” “reducing the appearance of my laugh lines — HYALURONIC SERUM”
- Deeply hydrating moisturizers Mostly Mentioned “Instantly quenches thirsty skin — Collagen Skin Rescue Lotion” “instant hydration for dry skin — HYALURONIC SERUM”
- Fast-absorbing serums Mostly Mentioned “Absorbs quickly and feels non-greasy — Retinol Advanced Firming Cream” “absorbs quickly — Vitamin C Anti Aging Serum”
- Fast-absorbing moisturizers Mostly Mentioned “Absorbs quickly — Collagen Skin Rescue Lotion” “absorbs well — HYALURONIC SERUM”
- Fragrance-free formulas Often Mentioned “It's fragrance-free, gentle even with retinol — Retinol Advanced Firming Cream” “No added scent — Collagen Skin Rescue Lotion”
- Skin dryness and irritation Often Mentioned “My skin immediately feels dry like it feels dehydrated — Retinol Advanced Firming Cream” “Caused minor breakout — Collagen Skin Rescue Lotion” “dried out my skin — Vitamin C Anti Aging Serum”
- Slightly sticky finish Often Mentioned “It's a little sticky but It absorbs well. — HYALURONIC SERUM” “leaves a sticky residue — Vitamin C Anti Aging Serum”

Sources: lovi.care, iherb.com, walmart.com, retinol.com, gopicky.com, amazon.com, and more

## Questions and answers

### Is Advanced Clinicals good for oily skin?

Advanced Clinicals is well suited for oily skin, as Lovi rates the Advanced Clinicals-focused routine Superior for this skin type. Reviewers often mention that the brand offers fast-absorbing [serums](https://lovi.care/skincare/ingredients/serum) and lightweight moisturizers that help keep oily skin comfortable.

### Is Advanced Clinicals worth it?

Advanced Clinicals is worth it for shoppers seeking budget-friendly options, as reviewers frequently mention great value and Lovi rates brand-focused routines Superior for oily, acne-prone, sensitive, and combination skin. The Advanced Clinicals products on this page are fragrance-free, though some users report skin dryness and irritation or a slightly sticky finish.

### What are Advanced Clinicals's best products?

[Vitamin C](https://lovi.care/skincare/ingredients/vitamin-c) Brightening Gel-Cream is among Advanced Clinicals's best products, as Lovi rates it High for skin with dark spots, mature skin, dry skin, dry sensitive skin, and sensitive skin. Reviewers also frequently mention its deep hydration and the brand's great value.

### Which Advanced Clinicals moisturizer is best for dry skin?

The Vitamin C Brightening Gel-Cream is the best choice, followed by the [Collagen](https://lovi.care/skincare/ingredients/collagen) Skin Rescue Lotion and HYALURONIC SERUM, as Lovi rates them High and Average for dry skin.

### Does Advanced Clinicals cause breakouts?

Advanced Clinicals is unlikely to cause breakouts when using their products on this page, as Lovi rates the Advanced Clinicals-focused routine Superior for acne-prone skin. Reviewers note that the formulas are fragrance-free, though some users mention occasional skin dryness and irritation.

### Is Advanced Clinicals fragrance-free?

Yes, the Advanced Clinicals products on this page list no fragrance in their ingredients. Reviewers often mention that these formulas are fragrance-free.

### What are the key ingredients in Advanced Clinicals products?

Advanced Clinicals products feature key ingredients such as [retinol](https://lovi.care/skincare/ingredients/retinol), vitamin C, collagen, and [hyaluronic acid](https://lovi.care/skincare/ingredients/hyaluronic-acid) to help improve skin texture and tone. Reviewers often mention that these fragrance-free formulas provide great value with fast-absorbing serums and deeply hydrating moisturizers.

[The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/) [Archives of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17515510/)

### How do I build a Advanced Clinicals skincare routine?

To build an Advanced Clinicals routine for dry skin, start your morning with a gentle cleanser, hydrating toner, Madagascar [Centella](https://lovi.care/skincare/ingredients/centella-asiatica) Probio-Cica Enrich Cream, and SPF. In the evening, use a pre-cleanser, cleanser, Vitamin C Anti Aging Serum, and the same cream, adding a nourishing mask once a week. Lovi rates the Advanced Clinicals-focused routine for dry skin as Superior.

### Where can I buy Advanced Clinicals, and how much does it cost?

Advanced Clinicals products on this page are available on Amazon US. Prices range from $9.46 to $9.46, with most falling between $9.46 and $9.46.

### What are good alternatives to Advanced Clinicals?

Good alternatives to Advanced Clinicals with pages on Lovi include CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica. These brands offer similar skincare options that may fit various skin types.

### Advanced Clinicals vs CeraVe: which is better?

Advanced Clinicals and CeraVe tie for dry, oily, sensitive, combination, and acne-prone skin, as Lovi rates their brand-focused routines as Superior for all of these skin types. Reviewers note that Advanced Clinicals offers great value with fast-absorbing serums and moisturizers, though some mention skin dryness, irritation, or a slightly sticky finish.

### Who owns Advanced Clinicals, and where is it from?

Advanced Clinicals is an American brand founded in 2005, owned by Concept Laboratories, Inc..

[tracxn.com](https://tracxn.com/d/companies/advanced-clinicals/__5SAKCpIAzQ6c5NRt4-PNS8xWIapHacc9Q2SepTdbIfM)

### Is Advanced Clinicals cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Advanced Clinicals as cruelty-free.

### Is Advanced Clinicals good for dry skin?

Advanced Clinicals is generally not the best choice for dry skin, as Lovi rates most of its products like Retinol Advanced Firming Cream and Collagen Skin Rescue Lotion Low for dry skin, though Vitamin C Brightening Gel-Cream is an exception with a High fit. Reviewers often mention skin dryness and irritation as a drawback, while the Advanced Clinicals-focused routine for dry skin achieves a Superior fit.

### Is Advanced Clinicals good for sensitive skin?

Advanced Clinicals rates Superior for sensitive skin when using the brand-focused routine. Reviewers often mention that the Advanced Clinicals products on this page are fragrance-free, though some users report skin dryness and irritation.

### Is Advanced Clinicals good for acne-prone skin?

Yes, Advanced Clinicals is good for acne-prone skin, as Lovi rates the brand-focused routine Superior for this skin type. Reviewers often mention that the products offer great value and help improve skin texture and tone.

### Is Advanced Clinicals good for skin with dark spots?

Advanced Clinicals is a good choice for skin with dark spots, as Lovi rates the Vitamin C Brightening Gel-Cream High for this skin type. Reviewers frequently note improved skin texture and tone from the range, and topical vitamin C helps brighten and improve signs of photodamage.

[Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Is Advanced Clinicals good for mature skin?

Yes, Advanced Clinicals is good for mature skin, especially with products like Vitamin C Brightening Gel-Cream, which Lovi rates High for mature skin. Reviewers often mention improved skin texture and tone. Additionally, topical retinol helps stimulate collagen accumulation in naturally aged human skin.

[The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/) [Archives of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17515510/)

## Research behind Advanced Clinicals's key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress](https://pubmed.ncbi.nlm.nih.gov/11181450/) Camellia sinensis · Carcinogenesis, 2001
- [Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes](https://pubmed.ncbi.nlm.nih.gov/23096708/) Camellia sinensis · The Journal of Investigative Dermatology, 2013
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomile · International Journal of Molecular Medicine, 2016
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin](https://pubmed.ncbi.nlm.nih.gov/30822414/) Camellia sinensis · The Journal of Investigative Dermatology, 2019
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Epilobium angustifolium extract demonstrates multiple effects on dermal fibroblasts in vitro and skin photo-protection in vivo](https://pubmed.ncbi.nlm.nih.gov/23817638/) Epilobium angustifolium stem extract flower leaf · General Physiology and Biophysics, 2013
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract](https://pubmed.ncbi.nlm.nih.gov/26203268/) Ginkgo biloba leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Apple Extract (Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin](https://pubmed.ncbi.nlm.nih.gov/32242497/) Pyrus malus fruit extract · Rejuvenation Research, 2020
- [Stability, antioxidant activity, in vivo safety and efficacy of creams with standardized wild apple fruit extract: a comparison of conventional and biodegradable emulsifiers](https://pubmed.ncbi.nlm.nih.gov/31050807/) Pyrus malus fruit extract · International Journal of Cosmetic Science, 2019
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Standardized wild apple fruit extract as a bioactive agent in dermocosmetic products for efficacy skin hydration-In vitro and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/35048513/) Pyrus malus fruit extract · Journal of Cosmetic Dermatology, 2022
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Preliminary evaluation of a comprehensive skincare regimen for enhancing skin health following advanced optimal pulse technology (AOPT) treatment](https://pubmed.ncbi.nlm.nih.gov/40497421/) Ergothioneine · International Journal of Cosmetic Science, 2025
- [Ergothioneine, collagen peptides, and sodium hyaluronate ameliorate facial skin aging via modulating oxidative stress, inflammation, and extracellular matrix homeostasis](https://pubmed.ncbi.nlm.nih.gov/42698538/) Ergothioneine · Frontiers in Nutrition, 2026

## Advanced Clinicals routines

- 90% fit: [Routine for dry skin](https://lovi.care/skincare/brands/advanced-clinicals/skincare-routine/for/dry-skin)
- 94% fit: [Routine for oily skin](https://lovi.care/skincare/brands/advanced-clinicals/skincare-routine/for/oily-skin)
- 93% fit: [Routine for combination skin](https://lovi.care/skincare/brands/advanced-clinicals/skincare-routine/for/combination-skin)
- 93% fit: [Routine for sensitive skin](https://lovi.care/skincare/brands/advanced-clinicals/skincare-routine/for/sensitive-skin)
- 94% fit: [Routine for acne-prone skin](https://lovi.care/skincare/brands/advanced-clinicals/skincare-routine/for/acne-prone-skin)
- 90% fit: [Routine for mature skin](https://lovi.care/skincare/brands/advanced-clinicals/skincare-routine/for/mature-skin)
- 91% fit: [Routine for skin with dark spots](https://lovi.care/skincare/brands/advanced-clinicals/skincare-routine/for/dark-spots)
- 89% fit: [Routine for dry sensitive skin](https://lovi.care/skincare/brands/advanced-clinicals/skincare-routine/for/dry-sensitive-skin)
- 93% fit: [Routine for oily acne-prone skin](https://lovi.care/skincare/brands/advanced-clinicals/skincare-routine/for/oily-acne-prone-skin)

## Similar brands

- American skincare: [CeraVe](https://lovi.care/skincare/brands/cerave)
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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi rates every product from its full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind these ratings: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

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- Ireland: https://lovi.care/skincare/ie/brands/advanced-clinicals
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