# The INKEY List Mandelic Acid Treatment for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [The INKEY List](https://lovi.care/skincare/au/brands/the-inkey-list)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate exfoliation for your normal skin due to the presence of mandelic acid and retinol, which provide keratolytic action and collagen stimulation respectively, but may not deliver optimal results for your wrinkles and fine lines.
- The formula provides general skincare benefits like hydration and cleansing, but the concentrations of mandelic acid and retinol are more supportive than directly targeting your primary concerns.
- The product is generally safe for your normal skin, with some risks of irritation due to the presence of mandelic acid and retinol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/oily-acne-prone-skin): High

## Key ingredients

Mandelic Acid, Glycerin, Retinol, Ethyl Ferulate, Helianthus Annuus Seed Oil

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Treatment with 45% mandelic acid peel showed nearly equal overall efficacy as 30% salicylic acid peel in patients with mild-to-moderate facial acne vulgaris, but with fewer adverse effects. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31553119/))
- Chemical peels using 35% glycolic acid, 20% salicylic-10% mandelic acid, and phytic acid reduce acne scores by 70.55%, 74.14%, and 69.7% respectively, and significantly decline the postacne hyperpigmentation index in Asian patients with mild to moderate acne. ([Journal of Cutaneous and Aesthetic Surgery, 2019](https://pubmed.ncbi.nlm.nih.gov/31619887/))
- Commonly used chemical peels showed no significant differences in effectiveness for acne vulgaris in most comparisons, though combined salicylic and mandelic acid peeling was superior to glycolic acid and glycolic acid was superior to placebo, based on twelve randomized controlled trials. ([BMJ Open, 2018](https://pubmed.ncbi.nlm.nih.gov/29705755/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))
- Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/40464749/))
- Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/))

## Why other serums fit mature skin better

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- A peptide complex stimulated basement membrane protein expressions and significantly improved skin wrinkles at all five measured sites after two weeks in 22 healthy Asian female volunteers older than 40 years. ([International Journal of Molecular Sciences, 2019](https://pubmed.ncbi.nlm.nih.gov/31861912/))
- A triple peptide complex synergistically stimulated collagen IV production in aged human fibroblasts and reduced periorbital wrinkle parameters compared to placebo in healthy Caucasian volunteers. ([Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20618556/))

## What reviewers say

Users find this treatment effective for fading post-acne marks and hyperpigmentation, with a high frequency of positive comments noting its gentleness on sensitive skin. Many reviewers also appreciate its ability to improve skin texture and its affordable price point. A significant number of users mention that visible results require patience and consistent daily use over several weeks, and some find the natural scent unpleasant or the product size small.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Gentle on skin (often mentioned)
- Disliked: Slow to show results (often mentioned)
- Liked: Affordable price (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Small product size (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Sticky texture (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does The INKEY List Mandelic Acid work for mature skin?

This treatment works moderately well for mature skin, offering gentle exfoliation and basic support, but it may not give you the best results for wrinkles and fine lines. A treatment for mature skin needs to be exceptionally safe with no risk of irritation, effectively target wrinkles and fine lines with high concentrations of potent antioxidants, and contain hydrating and skin-repairing ingredients to deliver optimal anti-aging results.

### Which ingredients make this exfoliant a good fit for mature skin?

Mandelic acid and retinol help this treatment fit mature skin by offering moderate exfoliation and supporting collagen. However, mature skin needs treatments that feature higher concentrations of potent anti-aging ingredients, strong antioxidants, and nourishing oils to effectively target fine lines and wrinkles while remaining completely safe from irritation.

### What does Mandelic Acid do for mature skin?

Mandelic acid helps make mature skin firmer and smoother while improving elasticity and reducing the look of fine lines and uneven tone. It is typically very well tolerated and may improve overall texture and hydration in dry or fragile skin over a few weeks of regular use.
Sources: [Facial Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/30513536/), [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40327578/)

### What does Glycerin do for mature skin?

Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this exfoliant go in a skincare routine for mature skin?

This treatment goes in your evening routine, starting at once a week so your skin can safely get used to it. Mature skin needs products with stronger smoothing ingredients and deeper hydration to effectively target wrinkles and fine lines.

### Can I use this exfoliant with niacinamide, and in what order?

You can use this treatment with niacinamide, applying the treatment first and following with niacinamide after it absorbs. This routine is generally safe, though combining active ingredients may raise the likelihood of skin irritation.

### How often should I use this exfoliant?

Start using this treatment once a week in your evening routine, and if your skin feels comfortable and you see good results, you can carefully use it more often. This product type for mature skin needs stronger active ingredients that directly target wrinkles and fine lines.

### Can this exfoliant clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores or cause breakouts for mature skin, though it may cause some irritation due to mandelic acid and retinol. To truly smooth out wrinkles and fine lines, mature skin needs stronger targeted ingredients like higher concentrations of retinol and collagen-boosting peptides.

### Is this exfoliant fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [Drunk Elephant A-Passioni Retinol Cream](https://lovi.care/skincare/au/p/drunk-elephant/a-passioni-retinol-cream/for/mature-skin) — High fit — A$71.86 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — A$50.60 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/au/p/la-mer/the-regenerating-serum/for/mature-skin) — High fit — A$740.13 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — A$73.61 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/au/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — A$37.00 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/au/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — A$116.08 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Mandelic Acid, Coco-Caprylate Caprate, Cetearyl Alcohol, Glycerin, Sodium Hydroxide, Caprylic Capric Triglyceride, Glyceryl Stearate, Candelilla Jojoba Rice Bran Polyglyceryl-3 Esters, Sodium Stearoyl Glutamate, Phenoxyethanol, Sodium Stearoyl Lactylate, Benzyl Alcohol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Carnauba Cera, Retinol, Polysorbate 20, Ethylhexylglycerin, Dehydroacetic Acid, Helianthus Annuus Seed Oil, Trisodium Ethylenediamine Disuccinate, 1,2-Hexanediol, Caprylyl Glycol, Disodium Cocoamphodiacetate, Tocopherol, Xanthan Gum, Ethyl Ferulate, Humulus Lupulus Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- France: https://lovi.care/skincare/fr/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-inkey-list/mandelic-acid-treatment/for/mature-skin