# SkinMedica HA5 Rejuvenating Hydrator for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [SkinMedica](https://lovi.care/skincare/au/brands/skinmedica)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers excellent hydration for your oily skin due to multiple forms of hyaluronic acid, such as sodium hyaluronate crosspolymer and hydrolyzed hyaluronic acid, which provide humectant action without overwhelming the skin with heavy emollients.
- While Vitis Vinifera Flower Cell Extract and Alteromonas Extract offer soothing benefits, the formula's primary focus on hydration does not directly address your main concerns of acne, blemishes, and breakouts.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Sodium Hyaluronate, Glycerin, Dimethicone, Vitis Vinifera Flower Cell Extract Grape Flower Cell Extract, Trehalose

## What the research says

- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Polyelectrolyte nanocomplexes of quaternized cyclodextrin grafted chitosan and low molecular weight hyaluronic acid improved skin texture and elasticity by increasing skin hydration in clinical evaluation. ([Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/))
- Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35775872/))
- Pre-treatment with Vitis vinifera L. water extract (100 ΓΙg/mL) demonstrated antioxidant and scavenger activity against UV-A radiation and exerted an anti-mutagenic effect by maintaining apoptosis in UV-A and UV-B irradiated human keratinocytes (HaCaT). ([Journal of Photochemistry and Photobiology. B, Biology, 2020](https://pubmed.ncbi.nlm.nih.gov/32028189/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments. ([Journal of Ocular Pharmacology and Therapeutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31298607/))
- Topical treatment with Thealoz Duo significantly improved dry eye disease symptoms, tear break-up time, and restored tear lipid layer functionality by reducing inflammatory response proteins in moderate to severe dry eye patients over 56 days. ([Journal of Clinical Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/40807147/))

## Why other moisturizers fit oily acne-prone skin better

- A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31347768/))
- Epigallocatechin-3-gallate significantly improved acne in patients compared to the control side during an 8-week clinical trial. ([The Journal of Investigative Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23096708/))

## What reviewers say

Based on a very large amount of data, users consistently praise this hydrator for its ability to deliver immediate, deep moisture that plumps the skin and smooths fine lines, often describing it as a "drink of water" for dry or aging complexions. The silicone-heavy formula provides a silky, primer-like finish that improves texture. Some users find the price point high and the application technique necessary to avoid product pilling.

- Liked: Intense hydration (mostly mentioned)
- Liked: Lightweight feel (often mentioned)
- Liked: Silky texture (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Chemical scent (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Risk of counterfeits (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does HA5 Rejuvenating Hydrator work for oily acne-prone skin?

SkinMedica HA5 Rejuvenating Hydrator works reasonably well for oily acne-prone skin by giving it plenty of moisture without feeling heavy, though it does not target breakouts directly. A product of this type needs acne-fighting ingredients like Niacinamide and soothing components like Allantoin to help calm blemishes and balance oil production.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/), [Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/)

### Which ingredients make this treatment a good fit for oily acne-prone skin?

Sodium hyaluronate crosspolymer and hydrolyzed hyaluronic acid help keep your oily skin hydrated without heavy oils, while Vitis Vinifera flower cell extract and alteromonas extract may help calm it. A product of this type for oily acne-prone skin needs ingredients that provide hydration and anti-inflammatory benefits for acne and blemishes, like niacinamide and allantoin, along with a lightweight texture that does not cause breakouts.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/), [Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### What does Glycerin do for oily acne-prone skin?

Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this treatment go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after your cleansing toner and before your moisturizer. It provides good hydration for oily skin, but because it does not directly target acne or breakouts, oily acne-prone skin needs a product of this type that also includes blemish-fighting ingredients and oil-balancing agents.

### Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol, applying the treatment first to hydrate your skin and following it with retinol. Using a hydrating moisturizer alongside retinol helps keep your skin comfortable and is unlikely to cause irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this treatment?

You can use this moisturizing treatment twice a day as part of your daily routine. Daily application helps keep your oily skin hydrated without heavy oils, though an oily acne-prone skin also needs targeted ingredients like salicylic acid or benzoyl peroxide to actively clear blemishes and breakouts.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this treatment clog pores, cause breakouts or purging for oily acne-prone skin?

This treatment is unlikely to clog pores or cause breakouts for oily acne-prone skin, as it is safe with no harsh ingredients. However, because its primary focus is hydration rather than acne, oily acne-prone skin needs a product of this type to also include targeted ingredients that help clear blemishes and prevent breakouts.

### Can I use this treatment around the eyes or on my body?

You can use this treatment around your eyes and on your body, but because skin thickness varies across the body—from thin eyelid skin to thicker areas—hydration needs differ by region. This product provides light hydration, whereas body and eye areas often benefit from targeted ingredients like hyaluronic acid to keep skin smooth and soft.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/au/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/oily-acne-prone-skin) — Superior fit — A$25.90 at Amazon
- [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/au/p/isntree/green-tea-fresh-serum/for/oily-acne-prone-skin) — High fit — A$34.00 at Amazon
- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/au/p/revision-skincare/hydrating-serum/for/oily-acne-prone-skin) — High fit — A$97.29 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/au/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — A$32.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — A$42.00 at Amazon
- SPF: [La Roche-Posay Anthelios Clear Skin Dry Touch Sunscreen SPF 60](https://lovi.care/skincare/au/p/la-roche-posay/anthelios-clear-skin-dry-touch-sunscreen-spf-60/for/oily-acne-prone-skin) — Superior fit — A$27.99 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Water, Dimethicone, Hdi Trimethylol Hexyllactone Crosspolymer, Glycerin, Butylene Glycol, Bis-Peg-8 Dimethicone, Polysilicone-11, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Sodium Hyaluronate Crosspolymer, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Vitis Vinifera Flower Cell Extract Grape Flower Cell Extract, Vibrio Alginolyticus Ferment Filtrate, Alteromonas Extract Ferment, Porphyridium Cruentum Extract, Whey Protein, Plankton Extract, Trehalose, Urea, Serine, Algin, Caprylyl Glycol, Pullulan, Disodium Phosphate, Potassium Phosphate, Pentylene Glycol, Polymethylsilsesquioxane, Glyceryl Polyacrylate, Sodium Citrate, Sea Water, Sucrose Palmitate, Tocopheryl Acetate, Hydroxyacetophenone, Polysorbate 60, Propanediol, Potassium Sorbate, Citric Acid, Isohexadecane, Polysorbate 80, Silica, Decyl Glucoside, Tromethamine, Ethylhexylglycerin, Phenoxyethanol, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinmedica/ha5-rejuvenating-hydrator/for/oily-acne-prone-skin