# REJURAN Turnover Ampoule Dual Effect for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [REJURAN](https://lovi.care/skincare/au/brands/rejuran)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- This product offers moderate moisturizing and treatment for your combination skin, with niacinamide helping to regulate oil and hyaluronic acid providing hydration. Blackberry Leaf Extract and Calendula Officinalis Flower Extract further soothe the skin, ensuring a gentle experience.
- While it provides general skincare benefits like hydration and soothing with ingredients such as Aloe Barbadensis Leaf Juice, it is not specifically targeted to address your acne, blemishes, and breakouts.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/oily-acne-prone-skin): Average

## Key ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Extract Licorice Extract, Calendula Officinalis Flower Extract

## What the research says

- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- A blackberry and dill extract combination synergistically increased skin elasticity and induced elastogenesis compared to each ingredient alone and placebo. ([International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/32583541/))
- Tropical highland blackberry juice reduced UVB-mediated DNA damage and increased apoptosis in human epidermal keratinocytes and a reconstituted skin equivalent model. ([Photochemistry and Photobiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23711186/))
- Strawberry and blackberry crude extracts, anthocyanin-enriched fractions, and proanthocyanidin-enriched fractions demonstrated anti-inflammatory effects through ROS reduction, gene expression inhibition, and NO suppression, while anthocyanin fractions promoted fibroblast migration in vitro. ([Food Research International, 2019](https://pubmed.ncbi.nlm.nih.gov/31108769/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Topical application of Glycyrrhiza glabra and Sophora japonica flavonoid-rich fractions individually and in combination significantly increased the wound healing rate and reduced oxidative stress compared to wound and Nolaver-treated groups. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37049756/))
- Topical application of Calendula officinalis extract cream significantly improved skin hydration and firmness (reflected in significant changes in R0 and R6 parameters) in 21 healthy human volunteers compared to a base cream. ([Acta Poloniae Pharmaceutica, 2011](https://pubmed.ncbi.nlm.nih.gov/21928714/))
- Treatment with standardized extract of Calendula officinalis L. led to a shorter epithelization time and faster healing speed compared to mineral oil in patients with acute skin loss wounds of the hand and fingers healing by secondary intention. ([Tissue Barriers, 2022](https://pubmed.ncbi.nlm.nih.gov/34674610/))
- Topical administration of Calendula provides weak evidence of effectiveness in acute and chronic wounds compared to standard treatments based on a narrative review of available trials. ([Wounds, 2008](https://pubmed.ncbi.nlm.nih.gov/25941793/))

## Why other moisturizers fit acne-prone skin better

- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31347768/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))

## What reviewers say

Users frequently report this ampoule delivers a desirable 'glass skin' effect, significantly enhancing hydration, radiance, and skin texture. Many also observe a reduction in fine lines and a strengthened skin barrier. However, some users find the price high for the quantity provided, and a few mention the texture can be too heavy for oily skin types or during warmer months.

- Liked: Deep hydration (mostly mentioned)
- Liked: Glow and radiance (often mentioned)
- Liked: Smoother texture (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Fast absorption (sometimes noted)
- Liked: Soothing and repair (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Caused irritation (rarely noted)
- Disliked: No results (rarely noted)
- Disliked: Sticky or heavy (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does REJURAN Turnover Ampoule Dual Effect work for acne-prone skin?

This product works for acne-prone skin by offering moderate hydration and soothing benefits, though other treatments target blemishes and breakouts more specifically. A product for this skin needs targeted blemish-fighting ingredients and oil-balancing components alongside reliable hydrators.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### Which ingredients make this serum a good fit for acne-prone skin?

Niacinamide and hyaluronic acid help regulate oil and provide hydration, while blackberry leaf extract and calendula officinalis flower extract soothe the skin. To work even better for acne-prone skin, this type of product needs targeted ingredients that directly address breakouts and blemishes.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### What does Blackberry Leaf Extract do for acne-prone skin?

Blackberry Leaf Extract helps calm angry skin and balances oil, making it a great addition to your routine if you deal with breakouts. It works to soothe redness and may help keep pores clear for a smoother, healthier look.

### What does Licorice Extract do for acne-prone skin?

Licorice extract helps calm red, angry blemishes and fades the dark spots left behind by breakouts. It also helps balance oil and soothe irritation, making it a great addition to your routine if you deal with frequent breakouts.
Sources: [Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/), [The Journal of Dermatological Treatment, 2003](https://pubmed.ncbi.nlm.nih.gov/14522625/)

### Where does it go in a skincare routine for acne-prone skin?

This product goes in the evening routine after cleansing and before moisturizing, as treatments with active ingredients are best used then for simplicity and safety around sun exposure. Acne-prone skin needs a product of this type to include ingredients that specifically target breakouts and blemishes while helping to regulate oil and calm the skin.

### Can I use this serum with retinol, and in what order?

You can use this moisturizing treatment with retinol by applying it before your retinol to keep your skin calm and hydrated. This type of routine helps minimize dryness and irritation while supporting your skin barrier during active treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use it?

You can use this treatment in the evening as part of your routine, and some treatments can also be used in the morning or twice a day. Applying it daily helps improve skin moisture and barrier function.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can it clog pores, cause breakouts or purging for acne-prone skin?

This product is unlikely to cause irritation on acne-prone skin, but because it is not specifically targeted to address breakouts, this skin type needs a moisturizing treatment that includes targeted blemish-fighting ingredients and oil-balancing agents.

### Can I use this serum around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it has a very safe formula with gentle, soothing ingredients that are unlikely to cause irritation. To properly care for acne-prone skin on the body, this type of product needs targeted blemish-clearing ingredients like salicylic acid or benzoyl peroxide.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/au/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/acne-prone-skin) — Superior fit — A$25.90 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/au/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin) — High fit — A$38.48 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/au/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/acne-prone-skin) — High fit — A$42.40 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/au/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — A$13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/au/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — A$34.66 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/au/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/acne-prone-skin) — Superior fit — A$80.43 at Amazon

## Where to buy

- Amazon.com.au: A$76.00 (https://www.amazon.com.au/dp/B08BZCY3Y1?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Extract Licorice Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract, Peg-6, Glycerin, Water, Hyaluronic Acid, Niacinamide, Dipropylene Glycol, Butylene Glycol, 1,2-Hexanediol, Carbomer, Gerotine Hydrolyzed Dna, Hydrolyzed Dna, Xanthan Gum, Polysorbate 20, Adenosine, Tocopheryl Acetate, Bisabolol, Arbutin, Ethylhexylglycerin, Caprylyl Glycol, Hexylene Glycol, Trehalose, Urea, Serine, Pentylene Glycol, Glyceryl Polyacrylate, Algin, Pullulan, Disodium Phosphate, Potassium Phosphate, Squalane, Hydrogenated Lecithin, Ceramide Np, Oleic Acid, Inulin Lauryl Carbamate, Cholesterol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/rejuran/turnover-ampoule-dual-effect/for/acne-prone-skin