# Peter Thomas Roth Retinol Fusion PM Night Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Peter Thomas Roth](https://lovi.care/skincare/au/brands/peter-thomas-roth)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate treatment for minimizing fine lines and wrinkles due to the presence of retinol, which promotes skin renewal for your normal skin.
- Bisabolol provides soothing benefits that are supportive for your redness and irritation, though it does not directly address these concerns.
- The product is safe for your normal skin with sensitivity, as it lacks prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Microencapsulated Retinol, Vitamins C, Squalane, Bisabolol, Cyclopentasiloxane

## What the research says

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Cyclomethicone and specific chain length cyclic siloxanes (n = 4-7) are safe in present practices of use and concentration, showing minimal percutaneous absorption, no skin irritation or sensitization, and unlikely significant systemic exposure from cosmetics. ([International Journal of Toxicology, 2011](https://pubmed.ncbi.nlm.nih.gov/22247236/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Application of an alpha-bisabolol-containing cream produced a significant skin-lightening effect in pigmented skin compared to a vehicle control in the majority of female subjects after 8 weeks. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20642768/))
- The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate reduces UVB-induced PGE2, inflammatory cytokines, and mitochondrial superoxide in human epidermal keratinocytes. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38433250/))

## What reviewers say

Based on a very large amount of data, this retinol serum is highly regarded for its anti-aging effects, including smoothing fine lines and improving skin texture, with most users experiencing a radiant and refined complexion without irritation. Some users reported a lack of visible results or found the thin consistency and premium price point to be drawbacks.

- Liked: Non-irritating formula (mostly mentioned)
- Liked: Reduces fine lines (often mentioned)
- Liked: Smoother texture (often mentioned)
- Liked: Absorbs quickly (sometimes noted)
- Liked: Radiant complexion (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Lack of results (sometimes noted)
- Disliked: Oily feel (rarely noted)
- Disliked: Thin consistency (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Peter Thomas Roth Retinol Fusion PM Night Serum work for sensitive skin?

This serum works moderately well for sensitive skin, helping smooth fine lines while bisabolol provides gentle soothing benefits. However, a treatment for this skin needs stronger calming ingredients like niacinamide and snail secretion filtrate along with rich hydrators to keep the face comfortable and calm.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this serum a good fit for sensitive skin?

Squalane and bisabolol help soothe and keep sensitive skin comfortable while retinol works on fine lines, though a treatment for this skin needs ingredients like niacinamide and snail secretion filtrate to better calm redness and irritation.

### What does Microencapsulated Retinol do for sensitive skin?

Microencapsulated retinol helps smooth and renew sensitive skin while lowering the likelihood of irritation compared to standard retinol. This delivery method helps maintain its strength over time and is generally well tolerated.
Sources: [Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38952060/)

### What does Vitamin C do for sensitive skin?

Vitamin C helps improve overall skin quality, fine lines, wrinkles, radiance, and dark spots in sensitive skin when used as part of a multi-step routine. It has a very safe profile and is well-tolerated.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37608511/), [Journal of Drugs in Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/39630676/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in your evening routine after cleansing and toning, and before moisturizing. Because this is an average fit for sensitive skin, a treatment for this skin needs soothing ingredients like bisabolol alongside gentle renewal to keep the skin calm and smooth.

### Can I use this serum with niacinamide, and in what order?

You can use this serum with niacinamide by applying niacinamide first and letting it absorb before putting on this retinol treatment. This combination helps smooth fine lines while keeping your skin calm, though sensitive skin may need to start slowly to avoid stinging.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### How often should I use this serum?

This serum works for sensitive skin when used once a week as part of your evening routine, as a slow start helps prevent irritation while your skin gets used to the retinol. Products of this type for sensitive skin need gentle soothing ingredients and slow introduction to keep skin calm and smooth.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts for sensitive skin because it lacks heavy or pore-clogging ingredients. Retinol may cause some mild initial purging or peeling as it speeds up skin renewal.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — A$50.60 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/au/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — A$27.50 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/au/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — A$34.41 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — A$73.61 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/au/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — A$54.00 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/au/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — A$24.49 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Cyclopentasiloxane, Squalane, Water, Retinol, Tocopheryl Acetate, Ascorbyl Palmitate, Bisabolol, Lecithin, Potassium Phosphate, Pentylene Glycol, Polysorbate-20, Alcohol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/peter-thomas-roth/retinol-fusion-pm-night-serum/for/sensitive-skin