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Peter Thomas Roth PEPTIDE SKINJECTION for oily acne-prone skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Peter Thomas Roth PEPTIDE SKINJECTION

Average

  • HighOily Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for oily acne-prone skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate benefits for your oily skin, as hyaluronic acid and glycerin provide essential hydration, while niacinamide helps regulate oil production and improve skin barrier resilience.
  • While it addresses general skincare needs like hydration and oiliness, it lacks targeted ingredients to effectively treat your primary concerns of acne, blemishes, and breakouts.
  • The product is safe for your oily skin, with no risks of irritation due to the absence of harsh or prohibited ingredients.

How to apply

  • Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
  • Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
  • Gently press a small amount into your skin and avoid rubbing to keep pores clear.
  • Apply on clean, slightly damp skin to help the product absorb better and control oil.
  • Avoid the sensitive eye area and do a simple patch test before your first use.

People Say

★4.6Overall rating based on 200+ reviews

This product line is highly praised for its effectiveness in softening fine lines and improving skin texture, with many users reporting smoother and more hydrated skin. Some users have noted a gritty texture in the serum and varying results for deep wrinkle reduction.

Highlights

  • Reduces fine lines Mostly Mentioned
    • “Big change in forehead lines”
    • “lines around eyes decreased”
    • “definite reduction in lines”
  • Smooths skin texture Often Mentioned
    • “Skin has never felt so smooth”
    • “makeup goes on smooth”
    • “melts into my skin”
  • Hydrating formula Sometimes Noted
    • “Thick hydrating feel”
    • “skin feels more hydrated”
    • “helps hydrate”
  • Reduces eye puffiness Sometimes Noted
    • “Less puffiness under eyes”
    • “quick relief of puffiness”
    • “noticed less puffiness”
  • Gritty serum texture Sometimes Noted
    • “Lotion has a little grit”
    • “texture is a little gritty”
    • “creamy and a bit gritty”
  • High price point Sometimes Noted
    • “hefty price”
    • “less hefty price”
  • Drying sensation Rarely Noted
    • “A bit drying”
    • “skin did not feel oily”
  • Slow/No results Rarely Noted
    • “Not noticed any reduction”
    • “only been 12 days”
    • “didn't last a week”

Sources: lovi.care, peterthomasroth.com, lovelyskin.com, dermstore.com, reddit.com, and more

Questions and answers

How well does Peter Thomas Roth Peptide Skinjection work for oily acne-prone skin?

This moisturizing treatment provides moderate benefits for oily skin by offering essential hydration and helping to balance oil production, but it lacks targeted ingredients to actively treat breakouts. To work best for acne-prone skin, a product of this type needs specialized blemish-fighting ingredients that clear pores while providing lightweight, non-greasy moisture.

Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2021

Which ingredients make this treatment a good fit for oily acne-prone skin?

Glycerin, hyaluronic acid, and niacinamide make this treatment a good fit by providing essential hydration and helping to balance oil production. However, for oily acne-prone skin, a product of this type needs targeted ingredients that actively treat breakouts and blemishes without clogging pores.

Clinical, Cosmetic and Investigational Dermatology, 2017Scientific Reports, 2024

What does Glycerin do for oily acne-prone skin?

Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.

The British Journal of Dermatology, 2008Clinical, Cosmetic and Investigational Dermatology, 2017

What does Tetrapeptide-1 do for oily acne-prone skin?

Tetrapeptide-1 helps support skin repair and keeps oily, acne-prone skin looking firm and smooth. It may also help calm the look of redness that often comes with breakouts.

Where does this treatment go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine, placed after cleansing and before moisturizing, and once a week during the weekly routine. Oily and acne-prone skin needs a moisturizing treatment of this type to also include targeted ingredients that actively treat breakouts, blemishes, and acne.

Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol, applying the treatment after your retinol has absorbed to help keep your skin comfortable. This type of product needs soothing ingredients and acne-fighting components to properly care for oily acne-prone skin.

Cutis, 2006Journal of Drugs in Dermatology, 2012

How often should I use this treatment?

You can use this treatment in the evening as part of your routine, or twice a day if your skin tolerates it well. It offers moderate hydration and helps balance oil, but an oily acne-prone skin needs targeted ingredients to clear blemishes and breakouts.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can this treatment clog pores, cause breakouts or purging for oily acne-prone skin?

This treatment is unlikely to clog pores or cause breakouts because it is safe for oily skin and has no harsh ingredients, though it lacks targeted blemish-fighting ingredients. Oily, acne-prone skin needs a product of this type to include ingredients like salicylic acid or retinoids that clear pores and keep breakouts under control.

Can I use this treatment around the eyes or on my body?

You can use this moisturizing treatment safely on your body and around your eyes, as it is unlikely to cause irritation. However, oily acne-prone skin needs products with targeted blemish-fighting ingredients for the body and lightweight hydration for the delicate eye area.

Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

    Journal of Cosmetic Dermatology, 2021

  • Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women.

    Scientific Reports, 2024

  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020

  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001

  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

Why other moisturizers fit oily acne-prone skin better

  • A Tris/Arg-formulated cleanser significantly decreased noninflammatory and inflammatory acne and pore size with keratotic plugs compared to an AEC/AC cleanser in male Thai subjects with mild to moderate acne over 4 weeks.

    Journal of Cosmetic Dermatology, 2020

  • Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients.

    The Australasian Journal of Dermatology, 1992

  • A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.

    Journal of Cosmetic Dermatology, 2024

Ingredients

Water, Glycerin, Chondrus Crispus Powder, Butylene Glycol, Tetrapeptide-1, Hyaluronic Acid, Allantoin, Trehalose, Caffeine, Squalane, Niacinamide, Adenosine, Tocopheryl Acetate, Calcium Lactate, Opuntia Ficus-Indica Flower Extract, Chondrus Crispus Extract, Chlorphenesin, Ricinus Communis Seed Oil Castor Seed Oil, Potassium Chloride, Dextrin, Sodium Phytate, Caprylyl Glycol, Citric Acid, Ceratonia Siliqua Gum, Xanthan Gum, Peg-60 Hydrogenated Castor Oil, Ultramarines, Chromium Hydroxide Green Ci 77289, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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How does it fit your skin?

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QR code: get the Lovi app
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