Peter Thomas Roth PEPTIDE SKINJECTION for dry skin

Glycerin
Tetrapeptide-1
Hyaluronic Acid
Average
- SuperiorDry Skin Fit
- HighEffectiveness
- HighSafety
Works for dry skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your dry or flaky skin, as hyaluronic acid and squalane provide essential hydration and moisturization. Glycerin and niacinamide further support your dry skin by acting as humectants and aiding in barrier repair.
- The formula is generally safe for your dry skin, with no harsh ingredients that would cause irritation.
- It provides excellent moisturizing properties suitable for dry skin, effectively hydrating and plumping your complexion.
How to apply
- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
People Say
★4.6Overall rating based on 200+ reviewsThis product line is highly praised for its effectiveness in softening fine lines and improving skin texture, with many users reporting smoother and more hydrated skin. Some users have noted a gritty texture in the serum and varying results for deep wrinkle reduction.
Highlights
Reduces fine lines Mostly Mentioned
- “Big change in forehead lines”
- “lines around eyes decreased”
- “definite reduction in lines”
Smooths skin texture Often Mentioned
- “Skin has never felt so smooth”
- “makeup goes on smooth”
- “melts into my skin”
Hydrating formula Sometimes Noted
- “Thick hydrating feel”
- “skin feels more hydrated”
- “helps hydrate”
Reduces eye puffiness Sometimes Noted
- “Less puffiness under eyes”
- “quick relief of puffiness”
- “noticed less puffiness”
Gritty serum texture Sometimes Noted
- “Lotion has a little grit”
- “texture is a little gritty”
- “creamy and a bit gritty”
High price point Sometimes Noted
- “hefty price”
- “less hefty price”
Drying sensation Rarely Noted
- “A bit drying”
- “skin did not feel oily”
Slow/No results Rarely Noted
- “Not noticed any reduction”
- “only been 12 days”
- “didn't last a week”
Sources: lovi.care, peterthomasroth.com, lovelyskin.com, dermstore.com, reddit.com, and more
Questions and answers
How well does Peter Thomas Roth Peptide Skinjection work for dry skin?
Peter Thomas Roth Peptide Skinjection works moderately well for dry skin, providing essential hydration through ingredients like hyaluronic acid and squalane while helping to keep your skin soft. A moisturizing treatment for dry skin needs rich hydrating ingredients and nourishing extracts to lock in moisture, smooth texture, and effectively soothe flakiness without any risk of irritation.
Which ingredients make this treatment a good fit for dry skin?
This moisturizing treatment is a good fit for dry skin because ingredients like hyaluronic acid, squalane, and glycerin help provide essential hydration and support skin barrier repair. Dry skin of this type needs rich moisturizing agents, nourishing extracts, and soothing ingredients that deliver deep hydration and lock in moisture without causing irritation.
What does Glycerin do for dry skin?
Glycerin helps dry skin by drawing in moisture and keeping it locked in, which makes the skin feel much softer and smoother. It also supports your natural skin barrier to stop water from escaping easily. A product for dry skin needs extra ingredients like hyaluronic acid and soothing plant extracts to truly calm and hydrate dry patches.
Clinical, Cosmetic and Investigational Dermatology, 2017The British Journal of Dermatology, 2008
What does Tetrapeptide-1 do for dry skin?
Tetrapeptide-1 helps dry skin by improving the outer protective barrier and supporting moisture retention. It enhances skin thickness and helps keep the surface smooth and well-hydrated.
Where does this treatment go in a skincare routine for dry skin?
This treatment goes in the evening routine after cleansing and before moisturizing, so you can apply it safely and simply. Dry skin of this type needs rich moisturizers with hyaluronic acid, glycerin, and squalane to deeply hydrate and repair the skin barrier.
Can I use this treatment with retinol, and in what order?
You can use this treatment alongside retinol by applying it before your retinol at night to help keep your skin comfortable and hydrated. This type of product works well for dry skin when it includes rich, barrier-supporting ingredients like ceramides and rich plant oils to lock in moisture.
How often should I use this treatment?
You can use this treatment in the evening as part of your routine. Daily application of this type of moisturizing treatment helps keep dry skin hydrated and comfortable.
Health Science Reports, 2021Journal of Cosmetic Dermatology, 2020
Can this treatment clog pores, cause breakouts or purging for dry skin?
This treatment is unlikely to clog pores or cause breakouts for dry skin, as its formula contains gentle hydrating ingredients and avoids harsh irritants. To care for dry skin even better, products of this type also need rich oils or butters that lock in moisture and deeply soften dry patches.
Can I use this treatment around the eyes or on my body?
This treatment works for dry skin around the eyes and on the body because its moisturizing ingredients like glycerin, hyaluronic acid, and squalane hydrate and soothe delicate areas. To truly thrive, very dry skin needs richer creams packed with heavier barrier-repairing oils and butters.
Is this treatment fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated.
Antioxidants, 2021The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019
Ingredients
Water, Glycerin, Chondrus Crispus Powder, Butylene Glycol, Tetrapeptide-1, Hyaluronic Acid, Allantoin, Trehalose, Caffeine, Squalane, Niacinamide, Adenosine, Tocopheryl Acetate, Calcium Lactate, Opuntia Ficus-Indica Flower Extract, Chondrus Crispus Extract, Chlorphenesin, Ricinus Communis Seed Oil Castor Seed Oil, Potassium Chloride, Dextrin, Sodium Phytate, Caprylyl Glycol, Citric Acid, Ceratonia Siliqua Gum, Xanthan Gum, Peg-60 Hydrogenated Castor Oil, Ultramarines, Chromium Hydroxide Green Ci 77289, Phenoxyethanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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