# Perricone MD Rejuvenating Moisturizer for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Perricone MD](https://lovi.care/skincare/au/brands/perricone-md)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your dry skin as Glycerin and Macadamia Ternifolia Seed Oil provide excellent moisturizing and barrier resilience, though it lacks more potent emollient ingredients for optimal results.
- The presence of S-Palmitoylglutathione offers antioxidant activity, complementing the hydration benefits for dry or flaky skin.
- The product is safe for your dry skin, containing no harsh ingredients and including soothing components like Glycerin and Macadamia Ternifolia Seed Oil.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/oily-acne-prone-skin): Average

## Key ingredients

Acyl-Glutathione, Tetrahexyldecyl Ascorbate, Ribose, Lactic Acid, Macadamia Ternifolia Seed Oil

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Application of a cream containing lactic acid 12% and pramoxine HCl 1% significantly improved skin dryness, hydration, and itch compared with a nontreated control in 24 women with a history of dry itchy skin. ([Cutis, 2004](https://pubmed.ncbi.nlm.nih.gov/15027519/))
- Topical 12% ammonium lactate produced a significant sparing of epidermal and dermal atrophy induced by clobetasol propionate in human volunteers, without influencing the corticosteroid's bioavailability or antiinflammatory properties. ([Journal of the American Academy of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1597538/))
- A lactic acid/ceramide lotion significantly improved skin moisturization and desquamation compared to no treatment in women with dry, rough skin on the anterior shins. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33178384/))

## Why other moisturizers fit dry skin better

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical oil-in-water and water-in-oil emulsions containing glyceryl glucoside, natural moisturizing factors, and ceramide significantly improved skin hydration and barrier function while reducing visible dryness and tactile roughness in subjects with very dry skin compared to untreated sites and vehicles. ([The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/))
- A 10% urea plus NMF moisturizer significantly improved total stratum corneum water content and the water gradient down to a depth of 15 μm compared to its vehicle in subjects with dry skin. ([Skin Research and Technology, 2022](https://pubmed.ncbi.nlm.nih.gov/35034387/))

## What reviewers say

This moisturizer is praised for its rich texture that plumps, firms, and smooths aging or dry skin without greasiness. Many users report reduced fine lines and improved radiance. Some users experienced product pilling or sensitivity to the fragrance.

- Liked: Deeply hydrating (often mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Non-greasy formula (sometimes noted)
- Liked: Reduces lines (sometimes noted)
- Disliked: Product pilling (sometimes noted)
- Disliked: Fragrance sensitivity (rarely noted)
- Disliked: White cast (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Perricone MD Rejuvenating Moisturizer work for dry skin?

This moisturizer works moderately well for dry skin, as glycerin and macadamia seed oil help hydrate and support the skin barrier, though other products fit this skin type better. To achieve optimal results for dry skin, a product of this type needs more potent emollient ingredients, rich moisture-retaining agents, and soothing components to ensure deep nourishment and comfort.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for dry skin?

Glycerin and Macadamia Ternifolia Seed Oil help make this cream a good fit for dry skin by providing solid moisture and barrier support. To work best for very dry skin, a product of this type needs richer emollients and stronger moisturizing ingredients like hyaluronic acid.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Acyl-Glutathione do for dry skin?

Acyl-glutathione helps protect dry skin by boosting antioxidant defenses and supporting moisture levels. It is unlikely to irritate dry skin and may help keep it feeling soft and smooth.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/)

### What does Vitamin C do for dry skin?

Vitamin C helps keep dry skin hydrated and makes it feel soft and smooth. Daily use may also improve overall skin texture and brightness over time.
Sources: [Photochemistry and Photobiology, 2021](https://pubmed.ncbi.nlm.nih.gov/33529350/), [Skin Research and Technology, 2008](https://pubmed.ncbi.nlm.nih.gov/19159387/)

### Where does it go in a skincare routine for dry skin?

This moisturizer goes in the morning routine after your hydrating toner and before your sunscreen, and in the evening routine as your final step after your treatment. It helps keep your skin soft and comfortable by providing moderate hydration and barrier support, though dry skin generally needs richer, more potent softening ingredients for optimal results.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying the retinol first and following it with this moisturizer to help keep your skin comfortable and hydrated. This type of skin needs a product packed with rich, heavy barrier-softening ingredients to achieve the best results on dry skin.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use it?

You can use this moisturizing treatment twice a day as part of your morning and evening routine to keep your dry skin soft and hydrated. Daily application helps improve skin moisture and supports the skin barrier, though dry skin generally needs richer emollient ingredients for optimal results.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for dry skin?

This moisturizing treatment is unlikely to clog pores or cause breakouts for dry skin, as it contains no harsh ingredients and is generally safe for your skin type. To truly comfort dry skin, this type of product needs richer softening ingredients to keep it feeling completely smooth.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use it around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body, as it has a very safe profile for the skin. However, because dry skin needs stronger softening ingredients and richer moisture for optimal results, a product of this type needs more potent emollients.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, citronellol, limonene, and linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/au/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — A$32.25 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/au/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-skin) — Superior fit — A$19.90 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/au/p/cosrx/advanced-snail-96-mucin-power-essence/for/dry-skin) — Superior fit — A$18.90 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/au/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — A$26.59 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/au/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — A$23.99 at Amazon
- SPF: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/au/p/bioderma/photoderm-mineral-fluide-spf50/for/dry-skin) — Superior fit — A$24.49 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Water, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, Peg-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum Seed Oil, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- France: https://lovi.care/skincare/fr/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/perricone-md/rejuvenating-moisturizer/for/dry-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/perricone-md/rejuvenating-moisturizer/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/perricone-md/rejuvenating-moisturizer/for/dry-skin