# PCA SKIN ExLinea Pro Peptide Serum for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [PCA SKIN](https://lovi.care/skincare/au/brands/pca-skin)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for mature skin.

## Why this fit

- Excellent for your normal skin, this serum effectively targets wrinkles and fine lines with acetyl octapeptide-3 and acetyl hexapeptide-8, which work to relax facial muscles and reduce the appearance of creases.
- Glycerin and sodium hyaluronate provide optimal hydration without overwhelming your skin, complementing the peptide action for a smoother, more youthful complexion.
- The formulation is safe for your skin, containing no harsh ingredients and posing no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Acetyl Octapeptide-3, Acetyl Hexapeptide-8, Sodium Hyaluronate, Hydrolyzed Wheat Protein, Glycerin

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model. ([International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Application of a cosmetic multiple emulsion containing vitamin C and wheat protein as well as a base formulation increased skin moisture in 11 human volunteers over four weeks, while producing no significant variations in skin sebum, pH, elasticity, melanin, or erythema. ([Pakistan Journal of Pharmaceutical Sciences, 2008](https://pubmed.ncbi.nlm.nih.gov/18166519/))
- The addition of polymers and hydrolysed proteins to model body wash cosmetics improves foaming properties, storage stability, and safety by reducing skin irritant potential, with the polyvinylpyrrolidone/hydrolysed wheat protein crosspolymer showing the strongest reduction effect. ([Colloids and Surfaces. B, Biointerfaces, 2015](https://pubmed.ncbi.nlm.nih.gov/26291586/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

This serum is highly praised for its effectiveness in reducing expression lines around the eyes, forehead, and mouth, with many users experiencing a noticeable smoothing or tightening effect. It is particularly favored by those with mature skin for enhancing texture and firmness. Some users, however, find the price to be high in relation to the results they observed.

- Liked: Reduces fine lines (often mentioned)
- Liked: Improves texture (sometimes noted)
- Liked: Lifts and firms (sometimes noted)
- Disliked: High price point (sometimes noted)
- Liked: Absorbs quickly (rarely noted)
- Disliked: Lack of results (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes PCA SKIN ExLinea Pro Peptide Serum a great fit for mature skin?

This serum is a great fit for mature skin because it targets wrinkles and fine lines using peptides like acetyl octapeptide-3 and acetyl hexapeptide-8 to relax facial muscles and smooth out creases. Glycerin and sodium hyaluronate add hydration to give you a more youthful complexion without irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### Which ingredients make this serum a good fit for mature skin?

Acetyl octapeptide-3 and acetyl hexapeptide-8 make this serum a great fit by relaxing facial muscles to target wrinkles and fine lines, while glycerin and sodium hyaluronate provide essential hydration for a smoother, more youthful look.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### What does Acetyl Octapeptide-3 do for mature skin?

Acetyl Octapeptide-3 helps smooth mature skin and reduce the look of fine lines by relaxing the muscle movements that cause wrinkles. It is unlikely to irritate your face and works well to keep skin looking firm and youthful.
Sources: [International Journal of Cosmetic Science, 2002](https://pubmed.ncbi.nlm.nih.gov/18498523/), [Frontiers in Medicine, 2026](https://pubmed.ncbi.nlm.nih.gov/41924746/)

### What does Argireline do for mature skin?

Argireline helps smooth out lines and makes mature skin look firmer and less rough when used twice a day. It may also help keep skin hydrated, though its penetration is naturally limited.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in the evening routine, placed after cleansing and before your moisturizer. Treatments with actives are used at night for simplicity and extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it after your retinol treatment, or on alternating nights to keep your skin calm and smooth. This safe routine helps target fine lines while keeping your skin comfortable.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. Using it daily helps smooth fine lines and keeps mature skin hydrated without irritation.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores, cause breakouts, or lead to purging on mature skin. Its formula uses lightweight hydration and smoothing peptides that are well tolerated and free of harsh irritants.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — A$50.60 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/au/p/la-mer/the-regenerating-serum/for/mature-skin) — High fit — A$740.13 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/au/p/augustinus-bader/the-serum/for/mature-skin) — High fit — A$639.95 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — A$73.61 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/au/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — A$37.00 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/au/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — A$116.08 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Pentylene Glycol, Glyceryl Isostearate, Isostearyl Isostearate, C13-15 Alkane, Betaine, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Methyl Gluceth-20, Rice Starch, Polyglyceryl-3 Laurate, Sodium Levulinate, Caprylyl Glycol, Levulinic Acid, Polyglyceryl-6 Oleate, Hydrolyzed Wheat Protein, Ethylhexylglycerin, Hydrolyzed Soy Protein, Sodium Hydroxide, Tetrasodium Glutamate Diacetate, Butylene Glycol, Pectin, Hydroxyethylcellulose, Arginine, Proline, Serine, Glucose, Acetyl Octapeptide-3, Bacillus Soybean Extract Ferment, Sodium Hyaluronate, Chondrus Crispus Extract, Acetyl Hexapeptide-8, Disodium Phosphate, Polysorbate 60, Sodium Phosphate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/pca-skin/exlinea-pro-peptide-serum/for/mature-skin