# numbuzin Pantothenic B5 Active Soothing Cream for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [numbuzin](https://lovi.care/skincare/au/brands/numbuzin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration and soothing for your combination skin, with niacinamide and panthenol supporting barrier repair and moisture retention. While beneficial for general skin health, these ingredients do not directly target your primary concerns of acne, blemishes, and breakouts.
- The formulation includes Centella Asiatica Extract and Panthenol, which are excellent for calming and hydrating, but lack specific actives to address acne.
- The product is safe for your acne-prone skin, as it avoids harsh ingredients and contains soothing components like Panthenol and Centella Asiatica Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/oily-acne-prone-skin): High

## Key ingredients

Pantothenic Acid Vitamin B5, Niacinamide, Centella Asiatica Extract, Aloe Barbadensis Flower Extract, Glycerin

## What the research says

- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## Why other moisturizers fit acne-prone skin better

- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

Based on a very large amount of data, this lightweight gel-cream is widely celebrated by users with oily and acne-prone skin for its ability to hydrate without clogging pores or leaving a greasy residue. While it effectively soothes redness and controls excess sebum, users with dry or dehydrated skin often find it lacks sufficient moisture, particularly during colder months.

- Liked: Lightweight gel texture (mostly mentioned)
- Liked: Soothing & calming (often mentioned)
- Disliked: Insufficient moisture (often mentioned)
- Liked: Non-comedogenic (sometimes noted)
- Liked: Sebum/oil control (sometimes noted)
- Disliked: Breakouts/Reactions (rarely noted)
- Disliked: Packaging concerns (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Numbuzin Pantothenic B5 Active Soothing Cream work for acne-prone skin?

This moisturizer offers moderate hydration and soothing for acne-prone skin, though other products fit this skin type better. To work effectively for acne-prone skin, a product of this type needs ingredients that directly target breakouts and blemishes while remaining non-irritating.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for acne-prone skin?

Pantothenic Acid Vitamin B5, Niacinamide, Centella Asiatica Extract, Aloe Barbadensis Flower Extract, and Glycerin make this cream a moderate fit by helping to calm and hydrate your skin. To achieve a better fit for acne-prone skin, this type of product needs ingredients that specifically target blemishes, breakouts, and acne while maintaining hydration without irritation.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Pantothenic Acid do for acne-prone skin?

Pantothenic acid helps reduce blemishes and total facial lesions in acne-prone skin. It is unlikely to cause irritation when used to clear up breakouts and calm the skin.
Sources: [Dermatology and Therapy, 2014](https://pubmed.ncbi.nlm.nih.gov/24831048/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does this cream go in a skincare routine for acne-prone skin?

This moisturizing treatment goes near the end of your morning and evening routines, right before sunscreen in the morning. While it hydrates and calms your skin, acne-prone skin needs products with targeted active ingredients to directly clear breakouts.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol, applying the treatment after your retinol absorbs to help keep your skin calm and moisturized. Using a barrier-supporting moisturizer helps reduce the dryness and irritation that often come with retinol use. To best care for acne-prone skin, this routine needs acne-fighting ingredients like salicylic acid or benzoyl peroxide to directly target blemishes.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily to help keep your skin calm and hydrated. Daily application of this type of cream supports moisture retention and barrier repair, though acne-prone skin needs added targeted blemish-fighting ingredients for best results.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to cause breakouts or purging for acne-prone skin, as it avoids harsh ingredients and contains soothing components like Panthenol and Centella Asiatica Extract. While it helps calm and hydrate, acne-prone skin needs products with specific blemish-fighting actives to fully address breakouts.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream around the eyes or on my body?

You can safely use this moisturizing treatment around the eyes and on the body because it avoids harsh ingredients and contains soothing components like panthenol and centella asiatica extract. It helps calm and hydrate the skin, though an eye area or body product for acne-prone skin also needs targeted blemish-fighting ingredients.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/au/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — A$24.00 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/au/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — A$18.90 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/au/p/belif/the-true-cream-aqua-bomb/for/acne-prone-skin) — High fit — A$50.56 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/au/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — A$13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/au/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — A$34.66 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/au/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/acne-prone-skin) — Superior fit — A$80.43 at Amazon

## Where to buy

- Amazon.com.au: A$32.29 (https://www.amazon.com.au/dp/B0CXSM1K2F?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 2 Nov 2026.

## Ingredients

Water, Butylene Glycol, Glycerin, Niacinamide, Cetyl Ethylhexanoate, Dicaprylyl Carbonate, 1,2-Hexanediol, Pentylene Glycol, Vinyl Dimethicone, Centella Asiatica Extract, Caprylyl Methicone, Erythritol, Panthenol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Dimethiconol, Polymethylsilsesquioxane, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Chlorella Vulgaris Extract, Glucose, Tromethamine, Silica, Fructooligosaccharides, Fructose, Sophora Angustifolia Root Extract, Ethylhexylglycerin, Xanthan Gum, Sodium Phytate, Glyceryl Acrylate Acrylic Acid Copolymer, Caprylic Capric Triglyceride, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Hydrogenated Lecithin, Ocimum Sanctum Leaf Extract, Tocopherol, Curcuma Longa Root Extract, Aloe Barbadensis Flower Extract, Solanum Melongena Fruit Extract, Decyl Glucoside, Corallina Officinalis Extract, Pantothenic Acid, Polyglyceryl-4 Caprate, Polyglyceryl-6 Caprylate, Camellia Sinensis Leaf Extract, Centella Asiatica Leaf Extract, Cladosiphon Okamuranus Extract, Willow Bark Extract, Houttuynia Cordata Extract, Coffea Arabica Seed Extract Coffee Seed Extract, Bergamot Leaf Extract, Pinus Densiflora Leaf Extract, Alpha-Arbutin, Zinc Pca, Argania Spinosa Kernel Oil, Methyl Diisopropyl Propionamide, Sesamum Indicum Seed Oil, Serenoa Serrulata Fruit Extract, Beta-Sitosterol, Glycyrrhiza Glabra Root Extract Licorice Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin