Numbuzin No.2 Protein 43% Creamy Serum for dry skin
Content Protein
Rice Seed Protein
Hydrolyzed Protein
Ceramide Np
Cholesterol
High
- HighDry Skin Fit
- SuperiorEffectiveness
- ExcellentSafety
A great choice for dry skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your dry skin as oat extract protein and ceramide np provide emollient and barrier repair actions, addressing your dry or flaky skin concerns with targeted moisturization.
- Rice seed protein and hydrolyzed corn protein further enhance hydration and smoothing texture, supporting your skin's barrier function.
- The formulation is safe for your dry skin, containing soothing ingredients and lacking harsh components.
How to apply
- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
People Say
★4.6Overall rating based on 300+ reviewsThis serum is widely praised as a "winter savior" for dry, sensitive, and dehydrated skin, effectively repairing damaged barriers and alleviating flakiness. Users consistently report a plump, healthy glow and deep "inner" hydration, though its rich, protein-heavy formula can be too heavy or potentially pore-clogging for oily or acne-prone skin types.
Highlights
Deep barrier repair Mostly Mentioned
- “strengthens my barrier”
- “calmed down sensitivity”
- “saviour for irritated skin”
Long-lasting hydration Often Mentioned
- “keeps skin from feeling dry”
- “inner dryness solved”
- “plump and hydrated”
Rich creamy texture Often Mentioned
- “perfect balance between cream and serum”
- “silky and nourishing”
- “absorbs beautifully”
Glowy finish Sometimes Noted
- “glass skin glow”
- “healthy shine”
- “makeup sits beautifully”
Not for oily skin Sometimes Noted
- “too heavy for oily skin”
- “greasy in summer”
- “better for winter”
Potential breakouts Sometimes Noted
- “got a break-out”
- “caused acne”
- “fermented ingredients didn't work”
Stickiness/tackiness Sometimes Noted
- “leaves a sticky residue”
- “slightly sticky feeling”
- “nasal mucus texture”
Packaging issues Rarely Noted
- “hard to get last bit out”
- “lid design inconvenient”
- “product sticks to container”
Sources: lovi.care, iherb.com, oliveyoung.com, stylekorean.com, reddit.com, yesstyle.com, and more
Questions and answers
What makes Numbuzin No.2 Protein 43% Creamy Serum a great fit for dry skin?
This serum is a great fit because oat extract protein and ceramide NP deeply moisturize dry skin and repair your skin barrier. Rice seed protein and hydrolyzed corn protein also help smooth your skin and boost lasting hydration.
Which ingredients make this serum a good fit for dry skin?
This serum is a great fit for dry skin because it contains oat extract protein and ceramide np, which help smooth away flakes and repair your skin barrier. Rice seed protein and hydrolyzed corn protein also work together to boost hydration and keep your skin soft.
What does Content Protein do for dry skin?
Content Protein helps dry skin by boosting hydration, making the skin feel soft and smooth, and reinforcing the skin barrier to lock in moisture. Topical application of similar peptide formulas has been shown to increase moisture levels and improve overall water-holding capacity.
Skin Research and Technology, 2008International Journal of Cosmetic Science, 2001
What does Rice Seed Protein do for dry skin?
Rice Seed Protein helps moisturize dry skin and calms irritation. It also supports the skin barrier and protects against damage from the sun.
Where does this serum go in a skincare routine for dry skin?
This serum goes in the evening routine after cleansing and before moisturizing. Using it at night keeps things simple and avoids extra sun sensitivity.
Can I use this serum with niacinamide, and in what order?
You can use this serum with niacinamide by applying niacinamide first and following with this moisturizing treatment. This combination helps smooth texture and restore moisture while keeping dry skin calm.
How often should I use this serum?
You can use this treatment in the evening as part of your routine for dry skin. Daily application of moisturizers and barrier-repair ingredients like ceramide NP helps keep dry or flaky skin smooth and hydrated.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this serum clog pores, cause breakouts or purging for dry skin?
This serum may cause breakouts for some, as reviewers note moderate complaints about potential blemishes. However, it is generally unlikely to irritate dry skin since its formulation includes soothing ingredients and lacks harsh components.
Can I use this serum around the eyes or on my body?
You can use this serum around the eyes and on your body as its gentle, moisturizing ingredients are safe for these areas. It helps hydrate dry or flaky skin and supports the skin barrier using proteins and ceramide NP.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.
Skin Pharmacology and Physiology, 2022Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion.
International Journal of Dermatology, 2008Topical application of oyster protein hydrolysates peptides protected against UVB-induced skin photodamage in mice by alleviating moisture loss, epidermal hyperplasia, and fiber degradation through antioxidant and anti-inflammatory mechanisms.
Marine Drugs, 2020Rice protein hydrolysate and its characteristic peptides Leu-Leu-Lys, Leu-Pro-Lys, and pyroGlu-Lys reduced melanin content, tyrosinase activity, and ROS production in UVB-induced human epidermal melanocyte PIG1 cells by regulating the JNK/Β-Trcp/NFΗB-p65/MITF signaling pathway and lowering TRP-1 and TRP-2 expression.
Food & Function, 2020A liquid formulation containing hydrolyzed collagen demonstrated structural stability, peptide mass distribution between 0.5 and 19.5 kDa, and faded forehead wrinkles in five volunteers while proving to be non-irritating and hypoallergenic.
Journal of Cosmetic Dermatology, 2021Combined treatment with human umbilical cord mesenchymal stem cell-derived exosomes and hydrolyzed collagen oligopeptides enhanced proliferation and migration, reduced reactive oxygen species and senescence-associated beta-galactosidase activity, increased type I and type III collagen expression, and decreased metalloproteinases, inflammatory cytokines, and senescence markers in human skin fibroblasts compared to either treatment alone.
Molecules, 2024Collagen peptides induced cell proliferation and pro-collagen-1α expression, increased TGF-β and VEGF, and suppressed the LPS-induced inflammatory response in human skin fibroblasts and keratinocytes.
Nutrients, 2022Botulinum toxin-A encapsulated in phosphatidylcholine/cholesterol nanoliposomes delivered transdermally achieved a diffusion depth of 380 μm and showed a nonsignificant advantage in relieving post-acne scarring compared to hyaluronic acid hydrogel treatment in 12 facial patients.
Journal of Materials Science. Materials in Medicine, 2024Topical application of cholesterol sulfate increases stratum corneum thickness and inhibits protease-induced cell dissociation by competitively inhibiting serine proteases in mice and human stratum corneum.
The Journal of Investigative Dermatology, 1998Topical lovastatin treatment impairs the recovery of cutaneous permeability barrier function and stratum corneum cholesterol levels after acetone disruption in mice, an effect normalized by simultaneous treatment with mevalonate or cholesterol.
The Journal of Clinical Investigation, 1990
Ingredients
Voat Extract Protein, Water, Cyclopentasiloxane, Butylene Glycol, Cetearyl Ethyl Hexanoate, Cyclohexasiloxane, Phenyl Trimethicone, Cetyl Pg, Sebum-10 1 Dimethicone, Hydrogenate Tid Poly, Rice Seed Protein, Prunus Amygdalus Dulcis Protein, Hydrolyzed Corn Protein, Hydrolyzed Protein, Hydrolyzed Pea Protein, Hydrolyzed Milk Protein, Glycine Soja Protein Soybean Protein, Hydrolyzed Lupine Protein, Ceramide Np, Cholesterol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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