# numbuz:n Pantothenic B5 Active Soothing Serum for acne-prone skin

**Lovi Fit: Superior fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [numbuz:n](https://lovi.care/skincare/au/brands/numbuz-n)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for acne-prone skin.

## Why this fit

- Excellent for your combination skin and acne, blemishes, and breakouts as Centella Asiatica Extract and its derivatives work to soothe inflammation and aid skin repair, complemented by Panthenol Vitamin B5 and Hyaluronic Acid for superior hydration and barrier support.
- The inclusion of Glycerin and Beta-Glucan further enhances humectant action and barrier resilience, ensuring your skin remains comfortable and well-nourished.
- This serum is safe for your skin, containing no harsh ingredients and featuring Panthenol Vitamin B5 and Centella Asiatica Extract to minimize irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin): Superior (this page)
- [Skin with dark spots](https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/oily-acne-prone-skin): Superior

## Key ingredients

Pantothenic Acid Vitamin B5, Hyaluronic Acid, Centella Asiatica Extract, Allantoin, Niacinamide

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## What reviewers say

This serum is widely praised by users with oily, acne-prone, and dehydrated skin for its ability to deeply hydrate without clogging pores or leaving a greasy residue. While many report significant improvements in redness and oil control, results vary for those with dry skin or specific sensitivities, with some users finding it insufficiently moisturizing on its own.

- Liked: Lightweight & fast (mostly mentioned)
- Liked: Hydrating for oily (often mentioned)
- Liked: Soothing redness (often mentioned)
- Liked: Oil control (sometimes noted)
- Disliked: Not enough moisture (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Price per volume (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes numbuz:n Pantothenic B5 Active Soothing Serum one of the best fits for acne-prone skin?

This serum is one of the best fits because Centella Asiatica Extract and its derivatives help soothe inflammation and repair skin, while Panthenol Vitamin B5 and Hyaluronic Acid provide deep hydration and support the skin barrier. It is very safe for acne-prone skin, using gentle ingredients to minimize irritation and keep your skin comfortable and smooth.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum is a great fit for your acne-prone skin because it contains Centella Asiatica Extract to soothe inflammation and repair skin, alongside Panthenol Vitamin B5 and Hyaluronic Acid for deep hydration and barrier support. Glycerin and Beta-Glucan add extra moisture to keep your skin comfortable and well-nourished without irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Pantothenic Acid do for acne-prone skin?

Pantothenic acid helps reduce blemishes and total facial lesions in acne-prone skin. It is unlikely to cause irritation when used to clear up breakouts and calm the skin.
Sources: [Dermatology and Therapy, 2014](https://pubmed.ncbi.nlm.nih.gov/24831048/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in your evening routine after cleansing and before your moisturizer. Putting it in the evening keeps things simple and adds extra safety around sun exposure, though it is gentle and safe for your skin.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, applying the serum first to keep your skin calm and hydrated while helping to lessen any dryness or irritation from the retinol. This combination is unlikely to cause issues because the soothing ingredients and gentle formula support your skin barrier during active treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

This serum is used in your evening routine, applying it once a day after cleansing. Daily application helps soothe breakouts, improve moisture, and support your skin barrier without irritation.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to cause breakouts on acne-prone skin because it contains soothing ingredients like centella asiatica extract and panthenol that help minimize irritation and support skin recovery. Reviewers rarely report breakouts from using it.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this serum around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on your body because it is very safe and gentle for delicate areas. Its blend of panthenol and centella asiatica extract helps calm redness and provides deep hydration while supporting the skin barrier.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/au/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/acne-prone-skin) — Superior fit — A$25.90 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/au/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin) — High fit — A$38.48 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/au/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/acne-prone-skin) — High fit — A$42.40 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/au/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — A$13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/au/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — A$34.66 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/au/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/acne-prone-skin) — Superior fit — A$80.43 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Water, Panthenol Vitamin B5, Glycerin, Butylene Glycol, Hyaluronic Acid, Allantoin, Centella Asiatica Extract, Madecassoside, Asiaticoside, Asiatic Acid, Madecassic Acid, Beta-Glucan, Sodium Pca, Tocopherol Vitamin E, Caprylyl Glycol, Ethylhexylglycerin, 1,2-Hexanediol, Carbomer, Arginine, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuz-n/pantothenic-b5-active-soothing-serum/for/acne-prone-skin