# No7 Protect & Perfect Intense Advanced Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [No7](https://lovi.care/skincare/au/brands/no7)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate anti-aging benefits for your combination skin, as Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-7 work to minimize fine lines and wrinkles. Glycerin and Sodium Hyaluronate provide hydration, which is beneficial for combination skin but does not directly address your oily shine concerns.
- The serum is formulated without harsh ingredients and includes Acetyl Dipeptide-1 Cetyl Ester, making it safe for your combination skin and unlikely to cause irritation.
- This product is safe for your skin as it lacks prohibited or harsh ingredients and contains soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Ascorbyl Phosphate, Retinyl Palmitate, Acetyl Dipeptide-1 Cetyl Ester, Hydrolyzed Rice Protein, Dimethicone

## What the research says

- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- Cosmetic products containing 4-t-butylcyclohexanol demonstrated a faster and more pronounced soothing effect on capsaicin-induced burning compared to those containing acetyl dipeptide-1 cetyl ester in volunteers with sensitive skin. ([Journal of the European Academy of Dermatology and Venereology, 2016](https://pubmed.ncbi.nlm.nih.gov/26805418/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Rice protein hydrolysate and its characteristic peptides Leu-Leu-Lys, Leu-Pro-Lys, and pyroGlu-Lys reduced melanin content, tyrosinase activity, and ROS production in UVB-induced human epidermal melanocyte PIG1 cells by regulating the JNK/Β-Trcp/NFΗB-p65/MITF signaling pathway and lowering TRP-1 and TRP-2 expression. ([Food & Function, 2020](https://pubmed.ncbi.nlm.nih.gov/32955075/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

Based on a very large amount of data, users with aging, dry, or combination skin frequently praise this serum for its silky texture and ability to instantly smooth and hydrate the skin. While many report visible improvements in fine lines and overall radiance after consistent use, results regarding deep wrinkles are mixed, with some users seeing significant firming and others noticing little change.

- Liked: Instant skin smoothing (mostly mentioned)
- Liked: Silky, lightweight texture (mostly mentioned)
- Liked: Quick absorption (often mentioned)
- Liked: Hydration and radiance (sometimes noted)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Lack of visible results (sometimes noted)
- Disliked: Silicone-heavy feel (sometimes noted)
- Disliked: Greasiness (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Protect & Perfect Intense Advanced Serum work for combination skin?

This serum works reasonably well for combination skin by offering moderate anti-aging benefits and hydration, but it does not directly address oily shine concerns. To fit combination skin better, a treatment of this type needs effective ingredients like niacinamide, propolis, or zinc PCA that regulate oiliness while providing balanced hydration without irritation.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

Palmitoyl oligopeptide and palmitoyl tetrapeptide-7 help smooth fine lines, while glycerin and sodium hyaluronate provide gentle hydration for combination skin. To work best for this skin type, a treatment of this kind needs ingredients like niacinamide, propolis, or zinc PCA to regulate oiliness and add radiance without extra shine.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Vitamin C do for combination skin?

Vitamin C helps balance combination skin by controlling excess oil in shiny areas while keeping dry patches soft and smooth. It also brightens dark spots and helps smooth out fine lines, giving your face an even, healthy look.
Sources: [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/), [Experimental Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22142309/)

### What does Retinyl Palmitate do for combination skin?

Retinyl palmitate helps smooth fine lines, even out skin tone, and improve texture on combination skin. Because it works gently, it is unlikely to cause irritation while helping keep both dry and oily areas looking clear and firm.
Sources: [Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23438139/), [Colloids and Surfaces. B, Biointerfaces, 2011](https://pubmed.ncbi.nlm.nih.gov/21411295/)

### Where does this serum go in a skincare routine for combination skin?

This treatment serum goes in your evening routine after cleansing and toning, and before your moisturizer. Combination skin also needs ingredients that help balance oily shine while providing hydration and anti-aging benefits.

### Can I use this serum with retinol, and in what order?

This serum is unlikely to cause irritation on your combination skin since it is formulated without harsh ingredients and contains soothing components, but because it already includes retinol-related ingredients, adding another strong product may overload your skin. To use them together safely, apply your separate retinol on alternate nights or pair this serum with lightweight, hydrating ingredients like glycerin and hyaluronic acid that keep your skin balanced without adding extra oily shine.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

This serum works well in your evening routine, as treatments fit best there for simplicity and extra safety around sun exposure. A product for your combination skin needs hydration to keep it balanced while also targeting oily shine and fine lines.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to cause breakouts or clogged pores on combination skin, as it is formulated without harsh ingredients and has a low risk of irritation. However, combination skin needs ingredients that help balance oily shine while providing hydration, along with lightweight, non-greasy textures.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of the European Academy of Dermatology and Venereology, 2016](https://pubmed.ncbi.nlm.nih.gov/26805418/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — A$16.95 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — A$52.32 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/au/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — A$639.95 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — A$73.61 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — A$42.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/au/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — A$22.99 at Amazon

## Where to buy

- Amazon.com.au: A$56.59 (https://www.amazon.com.au/dp/B01NCUXCIE?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Acetyl Dipeptide-1 Cetyl Ester, Water, Butylene Glycol, Carbomer, Cetyl Peg Ppg-10 1 Dimethicone, Dimethicone, Dimethicone Crosspolymer, Ethylhexylglycerin, Ethylparaben, Glycerin, Hexyl Laurate, Hydrolyzed Rice Protein, Hydroxyethylcellulose, Magnesium Sulfate, Medicago Sativa Extract, Methylparaben, Morus Alba Leaf Extract, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Panax Ginseng Root Extract, Peg Ppg-18 18 Dimethicone, Phenoxyethanol, Polyglyceryl-4 Isostearate, Polysorbate 20, Propylene Glycol, Retinyl Palmitate, Sodium Ascorbyl Phosphate, Sodium Benzoate, Sodium Hyaluronate, Sorbitan Laurate, Tocopherol, Tocopheryl Acetate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin