# NATURIUM Multi-Peptide Advanced Serum for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [NATURIUM](https://lovi.care/skincare/au/brands/naturium)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for oily skin, as Ferulic Acid and Glycerin provide antioxidant and humectant benefits, but it lacks sufficient ingredients for optimal oil control.
- The peptides like Acetyl Hexapeptide-8 and Copper Palmitoyl Heptapeptide-14 effectively minimize fine lines and wrinkles, addressing general skincare needs.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components like Glycerin and Tocopherol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Multi-Peptide Blend, Ferulic Acid, Hydrolyzed Collagen, Squalane, Acetyl Hexapeptide-8

## What the research says

- A topical antioxidant solution of 15% L-ascorbic acid, 1% alpha-tocopherol, and 0.5% ferulic acid provides significant photoprotection against solar-simulated UV radiation in human skin compared to its vehicle. ([Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- A topical serum with a peptide blend showed superior or comparable skin recovery to a moisturizer following fractional CO2 laser and radiofrequency microneedling in Asian subjects. ([Dermatology and Therapy, 2026](https://pubmed.ncbi.nlm.nih.gov/42322532/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))
- Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/40464749/))
- Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model. ([International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/))

## Why other serums fit oily skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

Users with dry, mature, and sensitive skin frequently praise this serum for its ability to visibly plump fine lines and deliver a "glass-skin" radiance without irritation. Many report smoother texture and improved hydration, while a minority of users experienced breakouts or frustration with the packaging design.

- Liked: Elegant texture (often mentioned)
- Liked: Hydrating and plumping (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Great value (sometimes noted)
- Liked: Visible anti-aging (sometimes noted)
- Disliked: Poor pump design (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Runs out quickly (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Naturium Multi-Peptide Advanced work for oily skin?

Naturium Multi-Peptide Advanced Serum works moderately well for oily skin, as it provides helpful antioxidant and smoothing benefits without causing irritation, though it lacks enough ingredients to properly control excess oil. Treatment of this type for oily skin needs ingredients like niacinamide or zinc PCA to manage shine and pores while keeping the skin balanced.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Which ingredients make this serum a good fit for oily skin?

This serum works for oily skin because ferulic acid and glycerin provide antioxidant and hydrating benefits without causing irritation. However, it lacks sufficient ingredients for optimal oil control. A product of this type needs ingredients like niacinamide and zinc PCA to manage excess oil and reduce shine while keeping the skin comfortable.

### What do Peptides do for oily skin?

Acetyl hexapeptide-8 reduces wrinkle depth, improves skin elasticity, and enhances hydration, though its low skin penetration can limit how well it works. For oily skin, it helps keep the face looking smooth while supporting moisture levels without feeling heavy.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/40565185/)

### What does Ferulic Acid do for oily skin?

Ferulic acid helps protect oily skin from sun damage and environmental stress when used as part of a daytime antioxidant serum. It is often combined with vitamins C and E to boost overall defense and keep skin healthy.
Sources: [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/), [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/)

### Where does this serum go in a skincare routine for oily skin?

This serum goes in the evening routine after cleansing and toning, and before moisturizing. Oily skin of this type needs a product with strong oil control and balancing ingredients.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying your retinol first and following it with this treatment to help smooth fine lines. This product is unlikely to irritate your skin because it lacks harsh ingredients and includes soothing components. Oily skin needs lightweight ingredients that help control excess oil while providing moisture.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. Oily skin needs a product with strong oil-controlling and balancing ingredients to fit best.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to clog pores or cause breakouts for oily skin, as it has a safe design without harsh ingredients. However, to truly fit oily skin, a product of this type needs dedicated oil-controlling and pore-balancing ingredients.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — A$16.95 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — A$52.32 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — A$50.60 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/au/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — A$13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/au/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — A$34.66 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/au/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — A$22.99 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Caprylic Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter Shea Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract Sunflower Extract, Rice Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Hexapeptide-13 Serine Sp Amide, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Lactic Acid Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/naturium/multi-peptide-advanced-serum/for/oily-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/naturium/multi-peptide-advanced-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/naturium/multi-peptide-advanced-serum/for/oily-skin