# Murad Retinal ReSculpt Overnight Treatment for mature skin

**Lovi Fit: Superior fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Murad](https://lovi.care/skincare/au/brands/murad)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for mature skin.

## Why this fit

- This treatment is an excellent match for your normal skin, as retinal effectively targets fine lines and wrinkles by stimulating collagen production and enhancing cell turnover, while glycerin and trehalose provide essential hydration.
- The inclusion of oat kernel extract and shea butter further supports skin comfort and barrier function, ensuring a soothing experience.
- The product boasts a strong safety profile with no reported irritation risks for normal skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin): Superior (this page)
- [Dry sensitive skin](https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/oily-acne-prone-skin): Average

## Key ingredients

Retinal, Squalane, Butyrospermum Parkii Butter Shea Butter, Avena Sativa Kernel Extract Oat Kernel Extract, Urea

## What the research says

- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Colloidal oatmeal induced skin barrier-related gene expression in vitro and showed significant clinical improvements in skin dryness, moisturization, and barrier in 50 healthy female subjects treated with a colloidal oatmeal lotion. ([Journal of Drugs in Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27272074/))
- Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model. ([Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/))
- A multiple W/O/W emulsion containing Rosmarinus officinalis L., Avena sativa L., and Linum usitatissimum L. extracts showed no irritant, phototoxic, inflammatory, or allergenic potential in human skin models and patch tests, establishing its safety as a cosmetic base. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/34065623/))
- Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index. ([Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29663701/))
- Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance. ([Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12218231/))
- Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients. ([Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts. ([Clinical, Cosmetic and Investigational Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30519069/))
- Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/))
- Colloidal oat increased the growth rate, metabolism, and lactic acid production of Staphylococcus epidermidis compared to Staphylococcus aureus in vitro, matching clinical increases in lactic acid on dry skin after 6 weeks of lotion use. ([Clinical, Cosmetic and Investigational Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33500646/))
- Topical 40% urea cream achieved improvement in less time and showed superiority over 12% ammonium lactate lotion in skin roughness, fissure reduction, thickness, and dryness at day 14 in patients treated for moderate to severe xerosis. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/11978141/))
- Topical treatment with K101 achieved a significantly higher mycological cure rate compared to placebo in patients with ≤50% nail involvement (27.2% vs 10.4%), while showing early visible improvements in nail appearance and no safety issues. ([Mycoses, 2012](https://pubmed.ncbi.nlm.nih.gov/22681227/))

## What reviewers say

Users report this treatment effectively targets advanced signs of aging, leading to visibly firmer, smoother, and bouncier skin. It is frequently praised for delivering results on deep wrinkles and sagging without the typical irritation associated with potent retinoids.

- Liked: Visibly smooths texture (mostly mentioned)
- Liked: Firms and lifts (often mentioned)
- Liked: Gentle and non-irritating (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Fast-acting results (sometimes noted)
- Liked: Pleasant consistency (sometimes noted)
- Disliked: Deceiving packaging (sometimes noted)
- Disliked: Lack of results (rarely noted)
- Disliked: Scent/Fragrance (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Murad Retinal ReSculpt Overnight Treatment one of the best fits for mature skin?

This treatment is an excellent match for mature skin because retinal effectively targets fine lines by boosting collagen and cell turnover, while glycerin and trehalose keep skin hydrated. Oat kernel extract and shea butter help soothe the skin and support the moisture barrier with a very low risk of irritation.
Sources: [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/), [Journal of Drugs in Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27272074/)

### Which ingredients make this treatment a good fit for mature skin?

Retinal makes this treatment a good fit for mature skin by smoothing fine lines, while squalane, shea butter, oat kernel extract, and urea help keep skin soft, hydrated, and calm. These ingredients work together safely to improve firmness and moisture without causing irritation.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/34065623/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/)

### What does Retinal do for mature skin?

Retinal helps smooth fine lines, improve uneven skin tone, refine texture, and tighten pores on mature skin. It may also boost skin thickness and elasticity over time while keeping irritation low compared to stronger options.
Sources: [Journal of Drugs in Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/39496127/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30027612/)

### What does Squalane do for mature skin?

Squalane helps keep mature skin feeling soft and smooth by boosting moisture and protecting the skin barrier. It also provides antioxidant support that helps improve the look of fine lines and wrinkles over time.
Sources: [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/), [Journal of Nanoscience and Nanotechnology, 2010](https://pubmed.ncbi.nlm.nih.gov/21137794/)

### Where does this treatment go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and toning, followed by a moisturizer. Putting treatments at night helps keep things simple and provides extra safety around sun exposure.

### Can I use this treatment with niacinamide, and in what order?

Yes, you can use this treatment with niacinamide, applying the niacinamide first and letting it absorb before putting on this treatment. Using them together helps smooth out fine lines while keeping your skin calm and hydrated, and it is unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this treatment?

You can use this treatment in your evening routine. Retinal helps smooth fine lines and renew skin, while glycerin, trehalose, shea butter, and oat extract keep your skin hydrated and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38406974/), [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36798538/)

### Can this treatment clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores or cause breakouts for mature skin, though the retinal it contains may cause temporary purging as it speeds up cell renewal. The formula also includes nourishing ingredients like squalane and shea butter, which help keep skin soft and comfortable.

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (citronellol and parfum). Cetearyl alcohol and cetyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for mature skin

- [Drunk Elephant A-Passioni Retinol Cream](https://lovi.care/skincare/au/p/drunk-elephant/a-passioni-retinol-cream/for/mature-skin) — High fit — A$71.86 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — A$50.60 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/au/p/la-mer/the-regenerating-serum/for/mature-skin) — High fit — A$740.13 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — A$73.61 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/au/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — A$37.00 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/au/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — A$116.08 at Amazon

## Where to buy

- Amazon.com.au: A$180.00 (https://www.amazon.com.au/dp/B0BWGXDCWJ?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 2 Nov 2026.

## Ingredients

Water, Diisostearyl Malate, Pentylene Glycol, Polyglyceryl-3 Methylglucose Distearate, Zea Mays Kernel Extract, Squalane, Propanediol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Glycerin, Cetearyl Alcohol, Glyceryl Ricinoleate, Avena Sativa Kernel Extract Oat Kernel Extract, Butyrospermum Parkii Butter Shea Butter, Retinal, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Anigozanthos Flavidus Extract, Phosphatidylcholine, Olea Europaea Leaf Extract Olive Leaf Extract, Mannitol, Ethylhexylglycerin, Dimethyl Isosorbide, Glyceryl Stearate, Sodium Stearoyl Glutamate, Cetyl Alcohol, Hectorite, Xanthan Gum, Sodium Chloride, Polysorbate 60, Sorbitan Isostearate, Leuconostoc Radish Root Ferment Filtrate, Tetrasodium Glutamate Diacetate, Citric Acid, Sodium Benzoate, Chlorphenesin, Potassium Sorbate, Citronellol, Alpha-Isomethyl Ionone, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- France: https://lovi.care/skincare/fr/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/murad/retinal-resculpt-overnight-treatment/for/mature-skin