# Medik8 Crystal Retinal 10 for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Medik8](https://lovi.care/skincare/au/brands/medik8)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate rejuvenation for your combination skin, as retinal and 3-o-ethyl ascorbic acid work to minimize fine lines and wrinkles, while squalane and carrot seed oil provide soothing benefits.
- While the formulation is generally hydrating and cleansing, it lacks specific ingredients to target your oily shine concerns.
- The product is safe for your combination skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of beneficial components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/oily-acne-prone-skin): Average

## Key ingredients

Retinal Vitamin A, Sodium Hyaluronate, Squalane, Tetrahexyldecyl Ascorbate, Eclipta Prostrata Extract

## What the research says

- Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate. ([Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/))
- Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model. ([International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/))
- Liposomal formulation of 3-O-ethyl-L-ascorbic acid enhanced skin retention and reduced UV-induced extracellular matrix degradation in skin explants compared to free EAA. ([Journal of Liposome Research, 2025](https://pubmed.ncbi.nlm.nih.gov/39985147/))
- Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index. ([Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29663701/))
- Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance. ([Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12218231/))
- Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients. ([Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10473959/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of petroleum ether and ethanol extracts of Eclipta alba significantly reduced the time required for hair growth initiation and completion in male albino rats compared to control animals, with the 5% petroleum ether extract showing a greater number of hair follicles in the anagenic phase (69 +/- 4) than the control (47 +/- 13). ([Archives of Dermatological Research, 2008](https://pubmed.ncbi.nlm.nih.gov/18478241/))
- Oral and topical administration of Eclipta prostrata promotes hair growth and enhances the induction of anagen in mice by increasing FGF-7 and decreasing FGF-5 expression. ([Pharmaceutical Biology, 2019](https://pubmed.ncbi.nlm.nih.gov/30757935/))
- Topical application of a polyherbal formulation containing Cuscuta reflexa, Citrullus colocynthis, and Eclipta alba extracts reduced hair growth initiation time to one third and complete hair growth time by 32% in rats compared with control animals. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17524127/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

This high-strength serum is highly regarded by users as an effective step-up for experienced retinoid users, leading to noticeable improvements in skin texture, firmness, and clarity. While it is praised for being gentler than many alternatives and beneficial for anti-aging and congestion, users should be aware of the potential for initial dryness or purging and the product's tendency to stain fabrics.

- Liked: Potent anti-aging (mostly mentioned)
- Liked: Elegant texture (often mentioned)
- Liked: Gentle formulation (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Clears congestion (sometimes noted)
- Disliked: Dryness/flaking (sometimes noted)
- Disliked: Initial purging (rarely noted)
- Disliked: Staining potential (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Medik8 Crystal Retinal 10 work for combination skin?

Medik8 Crystal Retinal 10 works moderately well for combination skin by smoothing fine lines and keeping skin soft, but it lacks specific ingredients to control oily shine. To truly fit this skin type, a product needs helpful ingredients like niacinamide, zinc PCA, or propolis to balance oiliness and enhance radiance without causing irritation.
Sources: [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/), [International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/)

### Which ingredients make this serum a good fit for combination skin?

This treatment is a moderate fit for your combination skin because retinal and 3-o-ethyl ascorbic acid help smooth fine lines, while squalane and carrot seed oil provide soothing benefits. To work best for combination skin, a product of this type needs ingredients like niacinamide, propolis, or zinc PCA to regulate oiliness and manage oily shine without irritation.
Sources: [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/), [International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/)

### What does Retinal do for combination skin?

Retinal helps smooth the skin and reduces signs of aging or breakouts when used regularly. It is unlikely to cause severe irritation when introduced gradually, keeping combination skin feeling calm and smooth.
Sources: [European Review for Medical and Pharmacological Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25219827/), [Journal of Cosmetic Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/21649816/)

### What does Hyaluronic Acid do for combination skin?

Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in the evening routine after your cleansing steps and before your moisturizer. Treatments with active ingredients are placed in the evening for simplicity and extra safety around sun exposure.

### Can I use this serum with niacinamide, and in what order?

You can use this treatment with niacinamide, applying the niacinamide first and letting it absorb before using this product. This approach helps keep your combination skin calm while addressing fine lines and wrinkles. To best care for combination skin, this type of product also needs ingredients that balance oily shine.

### How often should I use this serum?

This treatment is used in the evening as part of your routine. Combination skin needs ingredients to balance oily shine alongside soothing and smoothing components.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This treatment is unlikely to cause severe breakouts, though initial purging may happen at a low rate. Combination skin also needs lightweight hydrators and oil-balancing ingredients to keep pores clear and control shine.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (coumarin). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — A$16.95 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — A$52.32 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/au/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — A$639.95 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — A$73.61 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — A$42.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/au/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — A$22.99 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Water, Caprylic Capric Triglyceride, Glycerin, Isododecane, Cyclodextrin, Cetearyl Olivate, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Sorbitan Olivate, Tocopheryl Acetate, Squalane, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyacetophenone, Rubus Chamaemorus Seed Oil, 3-O-Ethyl Ascorbic Acid, Phenoxyethanol, Hydroxypropyl Methylcellulose, Pentylene Glycol, Daucus Carota Sativa Seed Oil Carrot Seed Oil, Retinal, Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Lonicera Japonica Flower Extract Honeysuckle Flower Extract, Lonicera Caprifolium Flower Extract Honeysuckle Flower Extract, Polyhydroxystearic Acid, Disodium Edta, Stearic Acid, Ethylhexylglycerin, Polysorbate 60, Sorbitan Isostearate, Bht, Vanilla Planifolia Fruit Extract Vanilla Fruit Extract, Sodium Polyaspartate, Dipteryx Odorata Extract Tonka Extract Bean Extract, Coumarin, Red 4, Titanium Dioxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medik8/crystal-retinal-10/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medik8/crystal-retinal-10/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/medik8/crystal-retinal-10/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/medik8/crystal-retinal-10/for/combination-skin
- France: https://lovi.care/skincare/fr/p/medik8/crystal-retinal-10/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/medik8/crystal-retinal-10/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/medik8/crystal-retinal-10/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/medik8/crystal-retinal-10/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/medik8/crystal-retinal-10/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/medik8/crystal-retinal-10/for/combination-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/medik8/crystal-retinal-10/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medik8/crystal-retinal-10/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medik8/crystal-retinal-10/for/combination-skin