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MEDIHEAL AGE-R for dry sensitive skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

MEDIHEAL AGE-R

Average

  • HighDry Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for dry sensitive skin; other serums fit it better.

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate benefits for dry skin as collagen and peptides provide humectant and barrier repair actions, though it lacks specialized ingredients to directly address flakiness.
  • The formula is highly suitable for dry skin and offers excellent skin firming and plumping effects.
  • The safety profile is excellent, with no risks of irritation for your dry and sensitive skin due to the absence of prohibited or harsh ingredients.

How to apply

  • Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
  • Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
  • Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
  • Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
  • Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.

People Say

★4.4Overall rating based on 12.5k+ reviews

Based on a very large amount of data, users frequently achieve a 'glass skin' appearance and improved facial contouring, with many reporting enhanced product absorption and a more radiant complexion. While effective for dullness and mild sagging, results are highly dependent on consistent daily use, which some users find difficult to maintain. The device is also noted for improving skin texture and reducing pore visibility.

Highlights

  • Enhanced absorption Mostly Mentioned
    • “products absorb instantly”
    • “skincare feels supercharged”
    • “no sticky residue left”
    • “serums work better”
  • Glass skin glow Often Mentioned
    • “skin looks dewy”
    • “immediate glass skin”
    • “glow lasts all day”
    • “makeup sits better”
  • Time-consuming routine Often Mentioned
    • “hard to stick to”
    • “adds 10 mins to routine”
    • “gave up after a month”
    • “too much effort daily”
  • Improved texture Sometimes Noted
    • “bumps smoothed out”
    • “pores look smaller”
    • “texture is softer”
    • “makeup applies smoother”
  • Visible lifting Sometimes Noted
    • “jawline looks snatched”
    • “face feels tighter”
    • “reduced morning puffiness”
    • “cheekbones pop more”
  • High price point Sometimes Noted
    • “very pricey investment”
    • “gel is expensive”
    • “not worth the full price”
    • “wait for a sale”
  • Unpleasant sensation Sometimes Noted
    • “zaps hurt sensitive areas”
    • “teeth feel weird”
    • “muscle twitching is creepy”
    • “prickly sensation”
  • Potential irritation Rarely Noted
    • “caused small bumps”
    • “redness after use”
    • “broke me out”
    • “too harsh for sensitive skin”

Sources: lovi.care, medicube.us, amazon.com, youtube.com, reddit.com, cosmopolitan.com, and more

Questions and answers

How well does the Mediheal AGE-R treatment work for dry sensitive skin?

Mediheal AGE-R treatment is an average fit for dry sensitive skin, offering firming and plumping effects with no irritation risks, though it lacks targeted ingredients for flakiness. A product of this type needs rich hydrating and nourishing components like ceramides and vitamin C to lock in moisture and protect this skin.

Dermatology Practical & Conceptual, 2022Current Issues in Molecular Biology, 2024

Which ingredients make this treatment a good fit for dry sensitive skin?

Glutathione, collagen, and peptides make this treatment a good fit because they help firm, plump, and improve moisture. However, because your skin is dry, a product of this type also needs ingredients like ceramides and vitamin C to lock in hydration and stop flakiness.

Clinical, Cosmetic and Investigational Dermatology, 2014Dermatology Practical & Conceptual, 2022

What does Glutathione do for dry sensitive skin?

Glutathione helps improve moisture content and smoothness while reducing oxidative stress, making it a helpful option for dry sensitive skin. This ingredient may enhance hydration and elasticity while maintaining a gentle profile. To properly care for dry sensitive skin, a product of this type needs soothing and hydrating ingredients that support the skin barrier.

Clinical, Cosmetic and Investigational Dermatology, 2014Journal of the European Academy of Dermatology and Venereology, 2024

What does Collagen do for dry sensitive skin?

Collagen helps dry sensitive skin by improving moisture, hydration, and overall barrier function to keep skin soft and smooth. It may also help reduce water loss and calm irritation as part of your daily routine.

Current Issues in Molecular Biology, 2024Dermatology Practical & Conceptual, 2022

Where does this treatment go in a skincare routine for dry sensitive skin?

This treatment goes in the evening routine for dry sensitive skin, placed after cleansing and toning and before moisturizing. This timing offers extra safety around sun exposure, and this type of skin needs added ingredients that directly address flakiness.

Can I use this treatment with retinol, and in what order?

You can use this treatment alongside retinol by applying the treatment first in your evening routine and following with retinol or a moisturizer to keep your dry and sensitive skin calm. To truly fit dry sensitive skin well, a product of this type needs specialized ingredients to directly address flakiness.

How often should I use this treatment?

You can use this treatment in your evening routine, applying it once a day or a few times a week. It is unlikely to irritate dry and sensitive skin, and a product of this type for your skin needs extra ingredients that directly target flakiness to give you the best fit.

Clinical, Cosmetic and Investigational Dermatology, 2014Dermatology Practical & Conceptual, 2022

Can this treatment clog pores, cause breakouts or purging for dry sensitive skin?

This treatment is unlikely to clog pores or cause breakouts for your dry and sensitive skin since its safety profile is excellent and it lacks harsh ingredients. It helps firm and plump your skin while keeping irritation risks low.

What the research says

  • Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen.

    Dermatology Practical & Conceptual, 2022

  • The use of cosmetic products containing collagen or its peptides improves the general condition of the skin, reduces wrinkle depth, improves hydration and density, reduces transepithelial water loss, and delays the aging process, while oral bioactive collagen peptides also reduce nail breakage.

    Current Issues in Molecular Biology, 2024

  • Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2014

  • Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls.

    Journal of the European Academy of Dermatology and Venereology, 2024

  • Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity.

    The Journal of Clinical and Aesthetic Dermatology, 2025

  • RayGel reduced skin reaction severity with a lower average score of 93.7 compared to 123.3 for the placebo group in patients undergoing whole breast external-beam irradiation.

    American Journal of Surgery, 2005

  • Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.

    Journal of Cosmetic Dermatology, 2022

  • Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.

    International Journal of Molecular Sciences, 2022

  • Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.

    Marine Drugs, 2023

Why other serums fit dry sensitive skin better

  • A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin.

    Acta Dermato-venereologica, 2017

  • Glycerol accelerates barrier repair and improves stratum corneum hydration compared to untreated and base-treated sites.

    Acta Dermato-venereologica, 1999

  • In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle.

    Skin Pharmacology and Physiology, 2026

Ingredients

Glutathione, Collagen, Peptides

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.

QR code: get the Lovi app
Download on theApp Store Get it onGoogle Play