# MEDIHEAL AGE-R for acne-prone skin

**Lovi Fit: Low fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/mediheal/age-r/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [MEDIHEAL](https://lovi.care/skincare/au/brands/mediheal)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for acne-prone skin; the serums alongside fit it better.

## Why this fit

- Offers moderate anti-aging benefits for your combination skin, as collagen and peptides provide plumping and hydration, but lacks ingredients to address your acne and breakouts.
- While the formula is generally safe and free of harsh irritants for combination skin, it does not contain specialized ingredients like salicylic acid to target blemishes.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/mediheal/age-r/for/oily-skin): Caution
- [Dry skin](https://lovi.care/skincare/au/p/mediheal/age-r/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/au/p/mediheal/age-r/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/au/p/mediheal/age-r/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/mediheal/age-r/for/acne-prone-skin): Low (this page)
- [Skin with dark spots](https://lovi.care/skincare/au/p/mediheal/age-r/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/au/p/mediheal/age-r/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/mediheal/age-r/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/mediheal/age-r/for/oily-acne-prone-skin): Caution

## Key ingredients

Glutathione, Collagen, Peptides

## What the research says

- Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen. ([Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/))
- The use of cosmetic products containing collagen or its peptides improves the general condition of the skin, reduces wrinkle depth, improves hydration and density, reduces transepithelial water loss, and delays the aging process, while oral bioactive collagen peptides also reduce nail breakage. ([Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))

## Why other serums fit acne-prone skin better

- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Based on a very large amount of data, users frequently achieve a 'glass skin' appearance and improved facial contouring, with many reporting enhanced product absorption and a more radiant complexion. While effective for dullness and mild sagging, results are highly dependent on consistent daily use, which some users find difficult to maintain. The device is also noted for improving skin texture and reducing pore visibility.

- Liked: Enhanced absorption (mostly mentioned)
- Liked: Glass skin glow (often mentioned)
- Disliked: Time-consuming routine (often mentioned)
- Liked: Improved texture (sometimes noted)
- Liked: Visible lifting (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Unpleasant sensation (sometimes noted)
- Disliked: Potential irritation (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why is Mediheal AGE-R a weak match for acne-prone skin?

Mediheal AGE-R is a weak match for acne-prone skin because it offers hydration and plumping for aging but lacks ingredients like salicylic acid, niacinamide, or zinc PCA to target blemishes and control oiliness. A treatment for acne-prone skin needs blemish-fighting ingredients and balancing agents to keep the skin clear without causing excess oiliness.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/), [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/)

### Which ingredients make this cream a poor fit for acne-prone skin?

This cream is a weak match for acne-prone skin because it relies on glutathione, collagen, and peptides, which provide hydration and smoothing rather than targeting breakouts. A treatment for this skin needs ingredients like niacinamide, propolis, or zinc PCA to help clear blemishes and control oil while keeping skin balanced.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/), [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/)

### What does Glutathione do for acne-prone skin?

Glutathione helps protect acne-prone skin against everyday environmental stress and oxidation. This ingredient is unlikely to clear breakouts on its own, so acne-prone skin needs a product that also targets pores, calms redness, and balances oil with ingredients like salicylic acid or niacinamide.
Sources: [Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/)

### What does Collagen do for acne-prone skin?

Collagen does not directly target breakouts, but it helps keep dry or aging acne-prone skin soft and hydrated without clogging pores. Because this skin type often needs lightweight moisture and soothing care, a product of this type needs non-greasy hydrators and calming ingredients to support clear skin.
Sources: [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/), [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30681787/)

### Where does this cream go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine, as Lovi routines place treatments in the PM for simplicity and extra safety around sun exposure. Because it is a weak match that lacks ingredients to address acne and breakouts, acne-prone skin needs a product of this type that also includes blemish-targeting ingredients like salicylic acid.

### Can I use it with retinol, and in what order?

You can use this treatment alongside retinol by applying your retinol first and following it with this product once it absorbs. This product is a weak match for your acne-prone skin because it lacks targeted blemish-fighting ingredients, so your routine for this skin type needs specialized ingredients like salicylic acid to properly clear breakouts.

### How often should I use this cream?

This treatment fits your acne-prone skin poorly because it lacks ingredients to target breakouts. To properly care for acne-prone skin, a product of this type needs blemish-fighting ingredients like salicylic acid alongside its plumping and hydrating benefits.

### Can it clog pores, cause breakouts or purging for acne-prone skin?

This treatment is unlikely to cause harsh irritation on acne-prone skin, but it lacks the specialized ingredients needed to actively address or prevent breakouts. A product of this type needs blemish-fighting ingredients like salicylic acid to properly care for acne-prone skin.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — A$16.95 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — A$52.32 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — A$50.60 at Amazon

## Routine for acne-prone skin

### AM

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/au/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — A$13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/au/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — A$34.66 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/au/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — A$24.00 at Amazon

### PM

- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/au/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/acne-prone-skin) — Superior fit — A$80.43 at Amazon
- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/au/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — A$13.99 at Amazon
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/au/p/pixi/glow-tonic/for/acne-prone-skin) — Superior fit — A$59.95 at Amazon
- Serum or Treatment: [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — A$16.95 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/au/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — A$24.00 at Amazon

### Weekly

- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/au/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/acne-prone-skin) — Superior fit — A$80.43 at Amazon
- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/au/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — A$13.99 at Amazon
- Enzyme Powder: [AmorePacific Treatment Enzyme Peel](https://lovi.care/skincare/au/p/amorepacific/treatment-enzyme-peel/for/acne-prone-skin) — High fit — A$83.06 at Amazon
- Cleansing Mask: [Herbivore Botanicals Blue Tansy Resurfacing Clarity Mask](https://lovi.care/skincare/au/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/acne-prone-skin) — Superior fit — A$118.35 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/au/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — A$34.66 at Amazon
- Serum or Treatment: [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — A$16.95 at Amazon

## Where to buy

No store in Australia has a checked price for this product, so the page shows none.

## Ingredients

Glutathione, Collagen, Peptides
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mediheal/age-r/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mediheal/age-r/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/mediheal/age-r/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/mediheal/age-r/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/mediheal/age-r/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/mediheal/age-r/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/mediheal/age-r/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/mediheal/age-r/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/mediheal/age-r/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/mediheal/age-r/for/acne-prone-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/mediheal/age-r/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mediheal/age-r/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mediheal/age-r/for/acne-prone-skin