# Medicube Zero Pore Serum 2.0 for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Medicube](https://lovi.care/skincare/au/brands/medicube)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- This formulation offers moderate pore-minimizing and skin-smoothing effects due to ingredients like fomes officinalis extract and cinnamomum zeylanicum bark extract, which are beneficial for general skin texture but do not specifically address your dry or flaky skin concerns.
- While butylene glycol provides some hydration, the lack of sufficient emollient and occlusive ingredients means it does not fully combat dryness.
- The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/oily-acne-prone-skin): Caution

## Key ingredients

Dimethicone, Mentha Rotundifolia Leaf Extract, Citrus Aurantifolia Peel Extract, Fomes Officinalis Extract Mushroom Extract

## What the research says

- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Aqueous extracts of apple mint leaves inhibited heat shock-induced production of reactive oxygen species, matrix metalloproteinases, interleukin-8, and mitogen-activated protein kinases in human dermal fibroblasts. ([Evidence-based Complementary and Alternative Medicine, 2018](https://pubmed.ncbi.nlm.nih.gov/30254686/))
- White button mushroom extract treatment increased VEGF densities, EGF, PCNA, and collagen fibers, while decreasing apoptotic cells and limiting TGF-beta and CD4 reactions in ICR mice and chorioallantoic culture, indicating beneficial effects on skin regeneration and injury. ([Microscopy Research and Technique, 2012](https://pubmed.ncbi.nlm.nih.gov/22581761/))

## Why other serums fit dry skin better

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin. ([Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/))

## What reviewers say

Users with oily and combination skin frequently report that this serum effectively regulates sebum and improves overall skin texture, creating a smoother base for makeup. While many users noticed a visible tightening of pores and a "glass skin" effect, results regarding actual pore size reduction are mixed, with some finding it highly effective and others seeing no significant change.

- Liked: Smoother skin texture (mostly mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Oil & sebum control (often mentioned)
- Disliked: Sticky texture (often mentioned)
- Liked: Pore tightening (sometimes noted)
- Disliked: Ineffective for some (sometimes noted)
- Disliked: Unpleasant fragrance (sometimes noted)
- Disliked: Price vs. quantity (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Medicube Zero Pore Serum work for dry skin?

Medicube Zero Pore Serum 2.0 works as an average fit for dry skin, smoothing texture while lacking enough softening and sealing ingredients to fully stop dryness. It is completely safe with no risk of irritation, but dry skin needs a richer blend of moisture-locking agents and nourishing ingredients to stay comfortable.
Sources: [Journal of Agricultural and Food Chemistry, 2012](https://pubmed.ncbi.nlm.nih.gov/22233457/), [Journal of Dermatological Science, 2019](https://pubmed.ncbi.nlm.nih.gov/31735467/)

### Which ingredients make this serum a good fit for dry skin?

Medicube Zero Pore Serum 2.0 has an average fit for dry skin because while butylene glycol provides some hydration, the formula lacks rich softening and sealing ingredients needed to fully lock in moisture and combat dryness. Dry skin needs formulas rich in soothing moisturizers like sodium hyaluronate and centella asiatica, alongside nourishing softening agents and heavy sealants to maintain optimal moisture levels.

### What does Water do for dry skin?

Drinking more water helps increase skin hydration and may reduce clinical signs of dryness and roughness, particularly for individuals with lower prior water consumption.
Sources: [Skin Research and Technology, 2018](https://pubmed.ncbi.nlm.nih.gov/29392767/)

### What does Dimethicone do for dry skin?

Dimethicone helps protect dry skin and keeps it smooth by forming a gentle, breathable layer on top. It is unlikely to lock in moisture on its own as well as heavy protectants like petrolatum, so dry skin often needs formulas that combine dimethicone with hydrating ingredients like glycerin.
Sources: [Ostomy/wound Management, 2005](https://pubmed.ncbi.nlm.nih.gov/16439809/), [Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in the evening routine for dry skin, after cleansing and before moisturizing. Because this product does not specifically address dry skin concerns, a product of this type needs rich moisturizing ingredients and oils to fully combat dryness.

### Can I use this serum with niacinamide, and in what order?

Yes, you can use this serum with niacinamide, applying the niacinamide first and letting it sink in before smoothing on this treatment. This serum is unlikely to irritate your dry skin, but dry skin needs a product packed with rich moisturizers and skin-softening ingredients to truly lock in hydration.

### How often should I use this serum?

This treatment works for your dry skin in the evening routine, though other products fit it better. It is unlikely to irritate dry skin, but dry skin needs richer hydrating ingredients and heavy softening or sealing ingredients to stay comfortable.

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to clog pores or cause breakouts for dry skin. It has a very safe profile with no harsh ingredients that typically trigger irritation.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [SKIN1004 Madagascar Centella Asiatica Ampoule](https://lovi.care/skincare/au/p/skin1004/madagascar-centella-asiatica-ampoule/for/dry-skin) — High fit — A$19.99 at Amazon
- [Purito Galacto Niacin 97 Power Essence](https://lovi.care/skincare/au/p/purito/galacto-niacin-97-power-essence/for/dry-skin) — High fit — A$36.00 at Amazon
- [Clarins Double Serum](https://lovi.care/skincare/au/p/clarins/double-serum/for/dry-skin) — Average fit — A$136.00 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/au/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — A$26.59 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/au/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — A$23.99 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/au/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — A$26.09 at Amazon

## Where to buy

- Amazon.com.au: A$31.40 (https://www.amazon.com.au/dp/B0DM86M2X7?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Dimethicone Vinyl Dimethicone Crosspolymer, Cyclopentasiloxane, Cetyl Ethylhexanoate, Cyclohexasiloxane, Polysorbate 60, Bis-Peg-18 Methyl Ether Dimethyl Silane, Glyceryl Stearate, Dimethicone, Peg-100 Stearate, Phenoxyethanol, Tromethamine, Chlorphenesin, Polyacrylate-13, Ethylhexylglycerin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Isoceteth-10, Caprylyl Glycol, Isoceteth-25, Carbomer, Polyisobutene, Disodium Edta, Mentha Rotundifolia Leaf Extract, Citrus Aurantifolia Peel Extract, Cymbopogon Schoenanthus Extract, Polysorbate 20, Sorbitan Isostearate, Camellia Japonica Flower Extract, Fomes Officinalis Extract Mushroom Extract, 1,2-Hexanediol, Cinnamomum Zeylanicum Bark Extract, Uncaria Gambir Extract, Nelumbo Nucifera Flower Extract, Pelargonium Graveolens Extract, Sanguisorba Officinalis Root Extract, Bht, Pinus Palustris Leaf Extract, Pueraria Lobata Root Extract, Ulmus Davidiana Root Extract, Oenothera Biennis Flower Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/zero-pore-serum-2-0/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/zero-pore-serum-2-0/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/zero-pore-serum-2-0/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/medicube/zero-pore-serum-2-0/for/dry-skin
- France: https://lovi.care/skincare/fr/p/medicube/zero-pore-serum-2-0/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/medicube/zero-pore-serum-2-0/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/zero-pore-serum-2-0/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/medicube/zero-pore-serum-2-0/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/zero-pore-serum-2-0/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/dry-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/zero-pore-serum-2-0/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/zero-pore-serum-2-0/for/dry-skin