# Medicube Zero Pore Serum 2.0 for combination skin

**Lovi Fit: Low fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: Concerning.

Page: https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Medicube](https://lovi.care/skincare/au/brands/medicube)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for combination skin; the serums alongside fit it better.

## Why this fit

- Offers moderate pore-minimizing and skin-smoothing effects for your combination skin, as Fomes Officinalis Extract and Cinnamomum Zeylanicum Bark Extract help control sebum and refine pores.
- Mentha Rotundifolia Leaf Extract and Cinnamomum Zeylanicum Bark Extract provide seboregulation and antimicrobial action, which are beneficial for oily shine.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/combination-skin): Low (this page)
- [Sensitive skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/oily-acne-prone-skin): Caution

## Key ingredients

Dimethicone, Mentha Rotundifolia Leaf Extract, Citrus Aurantifolia Peel Extract, Fomes Officinalis Extract Mushroom Extract

## What the research says

- Cinnamon extract and its component cinnamaldehyde up-regulate type I collagen mRNA and protein expression in human dermal fibroblasts via activation of IGF-I signaling without cytotoxicity. ([Journal of Agricultural and Food Chemistry, 2012](https://pubmed.ncbi.nlm.nih.gov/22233457/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Aqueous extracts of apple mint leaves inhibited heat shock-induced production of reactive oxygen species, matrix metalloproteinases, interleukin-8, and mitogen-activated protein kinases in human dermal fibroblasts. ([Evidence-based Complementary and Alternative Medicine, 2018](https://pubmed.ncbi.nlm.nih.gov/30254686/))
- White button mushroom extract treatment increased VEGF densities, EGF, PCNA, and collagen fibers, while decreasing apoptotic cells and limiting TGF-beta and CD4 reactions in ICR mice and chorioallantoic culture, indicating beneficial effects on skin regeneration and injury. ([Microscopy Research and Technique, 2012](https://pubmed.ncbi.nlm.nih.gov/22581761/))

## What reviewers say

Users with oily and combination skin frequently report that this serum effectively regulates sebum and improves overall skin texture, creating a smoother base for makeup. While many users noticed a visible tightening of pores and a "glass skin" effect, results regarding actual pore size reduction are mixed, with some finding it highly effective and others seeing no significant change.

- Liked: Smoother skin texture (mostly mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Oil & sebum control (often mentioned)
- Disliked: Sticky texture (often mentioned)
- Liked: Pore tightening (sometimes noted)
- Disliked: Ineffective for some (sometimes noted)
- Disliked: Unpleasant fragrance (sometimes noted)
- Disliked: Price vs. quantity (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why is Medicube Zero Pore Serum a weak match for combination skin?

Medicube Zero Pore Serum is a weak match for your combination skin because while it helps control oil and smooth pores, this skin type needs products with ingredients like niacinamide, propolis, and zinc PCA to provide balanced hydration and radiance without the risk of irritation or imbalance.
Sources: [Journal of Agricultural and Food Chemistry, 2012](https://pubmed.ncbi.nlm.nih.gov/22233457/)

### Which ingredients make this serum a poor fit for combination skin?

This serum is a weak match for combination skin because it lacks the ideal balance of ingredients found in better-suited options. A product for this skin type needs balancing and brightening ingredients like niacinamide, propolis, or zinc PCA to provide hydration and control oil without causing irritation or dryness.

### What does Water do for combination skin?

Water helps keep combination skin hydrated, though a product of this type needs additional barrier-protecting ingredients like ceramides or petrolatum to lock in that moisture and support overall skin health.

### What does Dimethicone do for combination skin?

Dimethicone helps protect combination skin by forming a light barrier that smooths the surface without feeling heavy or greasy. It may keep skin soft and comfortable, though it is unlikely to deeply moisturize dry areas or control excess oil on its own.
Sources: [Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/), [Skin Pharmacology and Physiology, 2014](https://pubmed.ncbi.nlm.nih.gov/24457536/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in your evening routine, after cleansing and before moisturizing, for simplicity and extra safety around sun exposure. Combination skin needs a product of this type to offer sebum control and pore-refining ingredients that help manage oily shine without drying out the skin.

### Can I use this serum with niacinamide, and in what order?

You can use this serum with niacinamide by applying niacinamide first and following with this treatment once it absorbs. Combination skin needs products that balance oil and hydration without causing dryness.

### How often should I use this serum?

You can use this serum in the evening as part of your routine. Combination skin needs products with sebum-controlling and pore-refining ingredients like Fomes Officinalis Extract and Cinnamomum Zeylanicum Bark Extract to manage oily shine.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is a weak match for combination skin and may feel sticky. Combination skin needs lightweight ingredients that hydrate without heaviness and balance oil without clogging pores.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — A$16.95 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — A$52.32 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/au/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — A$639.95 at Amazon

## Routine for combination skin

### AM

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — A$73.61 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — A$42.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/au/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — A$22.99 at Amazon

### PM

- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/au/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — A$30.99 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — A$73.61 at Amazon
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/au/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — A$29.90 at Amazon
- Serum or Treatment: [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — A$16.95 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/au/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — A$22.99 at Amazon

### Weekly

- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/au/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — A$30.99 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — A$73.61 at Amazon
- Enzyme Powder: [Fancl Facial Washing Powder](https://lovi.care/skincare/au/p/fancl/facial-washing-powder/for/combination-skin) — Superior fit — A$35.50 at Amazon
- Cleansing Mask: [Herbivore Botanicals Blue Tansy Resurfacing Clarity Mask](https://lovi.care/skincare/au/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — A$118.35 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/au/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — A$42.00 at Amazon
- Serum or Treatment: [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — A$16.95 at Amazon

## Where to buy

- Amazon.com.au: A$31.40 (https://www.amazon.com.au/dp/B0DM86M2X7?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Dimethicone Vinyl Dimethicone Crosspolymer, Cyclopentasiloxane, Cetyl Ethylhexanoate, Cyclohexasiloxane, Polysorbate 60, Bis-Peg-18 Methyl Ether Dimethyl Silane, Glyceryl Stearate, Dimethicone, Peg-100 Stearate, Phenoxyethanol, Tromethamine, Chlorphenesin, Polyacrylate-13, Ethylhexylglycerin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Isoceteth-10, Caprylyl Glycol, Isoceteth-25, Carbomer, Polyisobutene, Disodium Edta, Mentha Rotundifolia Leaf Extract, Citrus Aurantifolia Peel Extract, Cymbopogon Schoenanthus Extract, Polysorbate 20, Sorbitan Isostearate, Camellia Japonica Flower Extract, Fomes Officinalis Extract Mushroom Extract, 1,2-Hexanediol, Cinnamomum Zeylanicum Bark Extract, Uncaria Gambir Extract, Nelumbo Nucifera Flower Extract, Pelargonium Graveolens Extract, Sanguisorba Officinalis Root Extract, Bht, Pinus Palustris Leaf Extract, Pueraria Lobata Root Extract, Ulmus Davidiana Root Extract, Oenothera Biennis Flower Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/zero-pore-serum-2-0/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/zero-pore-serum-2-0/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/zero-pore-serum-2-0/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/medicube/zero-pore-serum-2-0/for/combination-skin
- France: https://lovi.care/skincare/fr/p/medicube/zero-pore-serum-2-0/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/medicube/zero-pore-serum-2-0/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/zero-pore-serum-2-0/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/medicube/zero-pore-serum-2-0/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/zero-pore-serum-2-0/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/combination-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/zero-pore-serum-2-0/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/zero-pore-serum-2-0/for/combination-skin