# Medicube EXOSOME CICA CALMING PAD for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Medicube](https://lovi.care/skincare/au/brands/medicube)
Category: [Toners](https://lovi.care/skincare/au/best/toners)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other toners fit it better.

## Why this fit

- Offers moderate soothing for your redness and irritation, as Exosome Cica and Niacinamide provide supportive benefits for your normal, sensitive skin by calming inflammation and repairing the skin barrier.
- The formulation is generally safe for your sensitive skin due to the absence of harsh ingredients, ensuring a low risk of irritation.
- While the product offers general soothing benefits, its impact on your specific concerns of redness and irritation is moderate rather than highly targeted.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/oily-acne-prone-skin): Average

## Key ingredients

Exosome Cica, Tree, Niacinamide

## What the research says

- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Dermocosmetic loaded with plant extract significantly improved skin texture and surface parameters including roughness, scaliness, smoothness, and wrinkles compared to a base without extract in Asian male volunteers over three months. ([Pakistan Journal of Pharmaceutical Sciences, 2020](https://pubmed.ncbi.nlm.nih.gov/32276894/))
- A cosmetic cream containing Harungana madagascariensis plant extract induces similar anti-aging effects to a retinol-containing cream on 46 human subjects, improving wrinkles, ptosis, color homogeneity, smoothness, plumpness, firmness, and elasticity. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37155516/))
- An OTC topical formulation containing a plant extract complex improved skin extensibility and firmness significantly (P < 0.02) compared to placebo in 20 volunteers, with no adverse reactions. ([International Journal of Cosmetic Science, 2000](https://pubmed.ncbi.nlm.nih.gov/18503475/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## Why other toners fit sensitive skin better

- Topical 7% ectoine during serial 1064-nm Nd:YAG laser therapy produced a greater reduction in skin erythema, improved stratum corneum hydration, reduced transepidermal water loss, and decreased low-echogenic pixels in thirty participants compared to a vehicle control. ([Biomedicines, 2026](https://pubmed.ncbi.nlm.nih.gov/42792808/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))

## What reviewers say

Based on a very large amount of data, users with sensitive and acne-prone skin frequently praise these pads for their immediate cooling and redness-reducing effects, often noting significant relief from facial heat and irritation. While most find them highly hydrating and effective for smoothing skin texture, a minority of users felt they were less effective for active blemishes or found the pad material slightly rough.

- Liked: Rapid soothing cooling (mostly mentioned)
- Liked: Hydrating non-sticky (often mentioned)
- Liked: Generous essence (sometimes noted)
- Liked: Gentle exfoliation (sometimes noted)
- Liked: High adherence (sometimes noted)
- Disliked: High price point (rarely noted)
- Disliked: Ineffective on acne (rarely noted)
- Disliked: Pad texture rough (rarely noted)
- Disliked: Strong scent (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this soothing toner 3×/week, and move to daily use if your skin likes it.
- Apply this soothing toner after your cleanser, and before your moisturizer or SPF.
- Gently press 2-3 drops of the soothing toner into your skin with your hands. Let it absorb for a minute before moving on.
- Since your skin is sensitive, apply this soothing toner on completely dry skin to make it feel extra comfortable.
- Be sure to avoid the eye area and do a quick patch test before your very first use.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### How well does medicube Exosome Cica Calming Pad work for sensitive skin?

The medicube EXOSOME CICA CALMING PAD works reasonably well for sensitive skin, offering moderate calm for redness and irritation through supportive ingredients while keeping the risk of irritation low. To fit this skin even better, a soothing toner needs highly targeted calming ingredients, rich hydration, and strong skin barrier support without any risk of irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/)

### Which ingredients make this toner a good fit for sensitive skin?

Exosome Cica, tree, and niacinamide help make this toner a good fit by calming inflammation and repairing your skin barrier with a low risk of irritation. A soothing toner for sensitive skin needs ingredients that effectively calm redness and hydrate without harsh risks.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/)

### What do Exosomes do for sensitive skin?

Exosomes help calm sensitive skin by reducing redness and irritation while supporting the skin's natural barrier. This type of product works best when it also includes soothing ingredients like ceramides and gentle hydrators to keep dry or easily irritated skin comfortable and protected.
Sources: [Cells, 2020](https://pubmed.ncbi.nlm.nih.gov/32164386/), [International Journal of Biological Sciences, 2024](https://pubmed.ncbi.nlm.nih.gov/38481799/)

### What does Tea Tree Oil do for sensitive skin?

Tea tree oil helps calm redness and swelling, but it is also known to cause skin irritation and allergic reactions in some people. Sensitive skin needs soothing and protective ingredients like niacinamide or ceramides to strengthen the skin barrier without the risk of contact allergy.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/)

### Where does this toner go in a skincare routine for sensitive skin?

This soothing toner goes after cleansing in both your morning and evening routines. It helps calm your skin, but sensitive skin with redness and irritation needs a product with targeted soothing ingredients and intensive barrier repair.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/)

### Can I use this toner with retinol, and in what order?

You can use this toner before your retinol in the evening to help calm and hydrate your skin. Using a gentle soothing toner first is unlikely to cause irritation and helps keep your skin comfortable while using retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this toner?

You can use this soothing toner in the morning and evening as part of your daily routine. It helps calm redness and irritation with a low risk of irritation, though sensitive skin needs a product that targets redness and irritation more strongly with soothing ingredients like centella asiatica and green tea extract.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/)

### Can this toner clog pores, cause breakouts or purging for sensitive skin?

This toner is unlikely to clog pores or cause breakouts on sensitive skin due to its gentle formula, though it may not do much to clear existing acne. A product of this type needs non-clogging soothing ingredients and a very soft texture to truly comfort easily irritated skin without causing issues.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/)

## Alternatives for sensitive skin

- [Medicube Super Cica Pad](https://lovi.care/skincare/au/p/medicube/super-cica-pad/for/sensitive-skin) — High fit — A$49.50 at Amazon
- [Dr. Jart+ Cicapair Toner](https://lovi.care/skincare/au/p/dr-jart/cicapair-toner/for/sensitive-skin) — High fit — A$51.80 at Amazon
- [Dr.G R.E.D Blemish Clear Soothing Toner](https://lovi.care/skincare/au/p/dr-g/r-e-d-blemish-clear-soothing-toner/for/sensitive-skin) — High fit — A$34.76 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — A$73.61 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/au/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — A$24.49 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/au/p/missha/ultra-hyalon-cleansing-cream/for/sensitive-skin) — Superior fit — A$27.35 at Amazon

## Where to buy

- Amazon.com.au: A$49.50 (https://www.amazon.com.au/dp/B0DFG4MRC9?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Exosome Cica, Tree, Niacinamide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/sensitive-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/exosome-cica-calming-pad/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/exosome-cica-calming-pad/for/sensitive-skin