# Medicube EXOSOME CICA CALMING PAD for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Medicube](https://lovi.care/skincare/au/brands/medicube)
Category: [Toners](https://lovi.care/skincare/au/best/toners)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other toners fit it better.

## Why this fit

- Offers moderate soothing for your dry and sensitive skin as exosome cica and niacinamide help calm redness and irritation, though it lacks specialized ingredients to fully address dryness or flakiness.
- Niacinamide aids in barrier repair for your dry skin, but the formula does not contain sufficient emollient ingredients for optimal hydration.
- The product is safe for your dry and sensitive skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/oily-acne-prone-skin): Average

## Key ingredients

Exosome Cica, Tree, Niacinamide

## What the research says

- Combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling significantly improved skin wrinkles, elasticity, hydration, and pigmentation compared to microneedling alone in twenty-eight individuals with facial skin aging. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37377400/))
- Topical application of 100% tea tree oil significantly reduced histamine-induced mean weal volume compared to control in twenty-seven volunteers. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Dermocosmetic loaded with plant extract significantly improved skin texture and surface parameters including roughness, scaliness, smoothness, and wrinkles compared to a base without extract in Asian male volunteers over three months. ([Pakistan Journal of Pharmaceutical Sciences, 2020](https://pubmed.ncbi.nlm.nih.gov/32276894/))
- A cosmetic cream containing Harungana madagascariensis plant extract induces similar anti-aging effects to a retinol-containing cream on 46 human subjects, improving wrinkles, ptosis, color homogeneity, smoothness, plumpness, firmness, and elasticity. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37155516/))
- An OTC topical formulation containing a plant extract complex improved skin extensibility and firmness significantly (P < 0.02) compared to placebo in 20 volunteers, with no adverse reactions. ([International Journal of Cosmetic Science, 2000](https://pubmed.ncbi.nlm.nih.gov/18503475/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## Why other toners fit dry sensitive skin better

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin. ([Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/))
- A cream containing panthenol, prebiotics, and probiotic lysate improved facial sensitive skin symptoms and skin barrier function in 110 participants over 28 days. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38186043/))

## What reviewers say

Based on a very large amount of data, users with sensitive and acne-prone skin frequently praise these pads for their immediate cooling and redness-reducing effects, often noting significant relief from facial heat and irritation. While most find them highly hydrating and effective for smoothing skin texture, a minority of users felt they were less effective for active blemishes or found the pad material slightly rough.

- Liked: Rapid soothing cooling (mostly mentioned)
- Liked: Hydrating non-sticky (often mentioned)
- Liked: Generous essence (sometimes noted)
- Liked: Gentle exfoliation (sometimes noted)
- Liked: High adherence (sometimes noted)
- Disliked: High price point (rarely noted)
- Disliked: Ineffective on acne (rarely noted)
- Disliked: Pad texture rough (rarely noted)
- Disliked: Strong scent (rarely noted)

## How to apply

- You can use this soothing toner AM and PM every day. Always pair with SPF in the morning.
- Apply this soothing toner after your cleanser and before your moisturizer .
- Gently press 2-3 drops of the soothing toner into your skin and let it absorb. Avoid rubbing.
- Apply the soothing toner on slightly damp skin to help with absorption. This is great for dry skin.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### How well does medicube Exosome Cica Calming Pad work for dry sensitive skin?

This toner works moderately well for your dry sensitive skin, as exosome cica and niacinamide help calm redness while niacinamide aids in barrier repair. It is safe and unlikely to cause irritation, but it lacks sufficient moisturizing ingredients to fully address dryness and flakiness. Soothing toners that fit dry sensitive skin better need rich hydrating ingredients and moisture-locking components to keep skin soft and comfortable.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/)

### Which ingredients make this toner a good fit for dry sensitive skin?

Exosome cica and niacinamide make this toner a good fit for your dry sensitive skin by helping calm redness and irritation while supporting barrier repair. However, this product of this type needs rich hydrating ingredients and softening agents to fully address dryness and flakiness.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What do Exosomes do for dry sensitive skin?

Exosomes help calm dry sensitive skin by locking in moisture and repairing the outer skin barrier so it feels much smoother and less irritated. This type of care works best when it includes gentle, deeply soothing ingredients like ceramides and plant extracts to keep the skin soft and protected.
Sources: [Cells, 2020](https://pubmed.ncbi.nlm.nih.gov/32164386/), [Pharmaceutics, 2025](https://pubmed.ncbi.nlm.nih.gov/40430891/)

### What does Tea Tree Oil do for dry sensitive skin?

Tea tree oil is generally too strong for dry sensitive skin and may cause irritation or allergic reactions at high concentrations. This type of skin needs gentle, soothing ingredients that restore moisture and protect the skin barrier without causing redness.
Sources: [Food and Chemical Toxicology, 2006](https://pubmed.ncbi.nlm.nih.gov/16243420/)

### Where does this toner go in a skincare routine for dry sensitive skin?

This soothing toner goes right after cleansing in your morning and evening routine, before you apply your moisturizer or treatment. It is unlikely to cause irritation on dry and sensitive skin since it avoids harsh ingredients.

### Can I use this toner with retinol, and in what order?

You can use this toner in your evening routine before your retinol treatment. It is unlikely to cause irritation for your dry and sensitive skin, but a soothing toner of this type works best for you when it also includes rich softeners and oils to deeply tackle dryness.

### How often should I use this toner?

You can use this soothing toner in your morning and evening routines because it is safe and unlikely to cause irritation on dry and sensitive skin. However, since this product type works best when it is paired with rich, nourishing ingredients that fully address dryness and flakiness, you may need an extra moisturizer to keep your skin comfortable.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12452873/)

### Can this toner clog pores, cause breakouts or purging for dry sensitive skin?

This soothing toner is unlikely to clog pores or cause breakouts for dry and sensitive skin since it is safe and free of harsh ingredients that typically trigger irritation. A product of this type needs richer, moisturizing ingredients and gentle hydrators to fully care for dry skin without leaving it feeling flaky.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

## Alternatives for dry sensitive skin

- [Medicube Super Cica Pad](https://lovi.care/skincare/au/p/medicube/super-cica-pad/for/dry-sensitive-skin) — High fit — A$49.50 at Amazon
- [Dr. Jart+ Cicapair Toner](https://lovi.care/skincare/au/p/dr-jart/cicapair-toner/for/dry-sensitive-skin) — High fit — A$51.80 at Amazon
- [COSRX Cica Toner](https://lovi.care/skincare/au/p/cosrx/cica-toner/for/dry-sensitive-skin) — High fit — A$24.78 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/au/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — A$19.39 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/au/p/bioderma/photoderm-mineral-fluide-spf50/for/dry-sensitive-skin) — Superior fit — A$24.49 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/au/p/missha/ultra-hyalon-cleansing-cream/for/dry-sensitive-skin) — Superior fit — A$27.35 at Amazon

## Where to buy

- Amazon.com.au: A$49.50 (https://www.amazon.com.au/dp/B0DFG4MRC9?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Exosome Cica, Tree, Niacinamide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin