# Medicube EXOSOME CICA CALMING PAD for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Medicube](https://lovi.care/skincare/au/brands/medicube)
Category: [Toners](https://lovi.care/skincare/au/best/toners)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other toners fit it better.

## Why this fit

- Offers moderate soothing for your combination skin as Exosome Cica and Niacinamide help calm redness and irritation, while also providing hydration and pore-minimizing effects for oily shine.
- The ingredients are highly suitable for combination skin due to Niacinamide's seboregulation and Exosome Cica's anti-inflammatory action.
- The product has no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/mature-skin): Low
- [Dry sensitive skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/oily-acne-prone-skin): Average

## Key ingredients

Exosome Cica, Tree, Niacinamide

## What the research says

- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Dermocosmetic loaded with plant extract significantly improved skin texture and surface parameters including roughness, scaliness, smoothness, and wrinkles compared to a base without extract in Asian male volunteers over three months. ([Pakistan Journal of Pharmaceutical Sciences, 2020](https://pubmed.ncbi.nlm.nih.gov/32276894/))
- A cosmetic cream containing Harungana madagascariensis plant extract induces similar anti-aging effects to a retinol-containing cream on 46 human subjects, improving wrinkles, ptosis, color homogeneity, smoothness, plumpness, firmness, and elasticity. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37155516/))
- An OTC topical formulation containing a plant extract complex improved skin extensibility and firmness significantly (P < 0.02) compared to placebo in 20 volunteers, with no adverse reactions. ([International Journal of Cosmetic Science, 2000](https://pubmed.ncbi.nlm.nih.gov/18503475/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## What reviewers say

Based on a very large amount of data, users with sensitive and acne-prone skin frequently praise these pads for their immediate cooling and redness-reducing effects, often noting significant relief from facial heat and irritation. While most find them highly hydrating and effective for smoothing skin texture, a minority of users felt they were less effective for active blemishes or found the pad material slightly rough.

- Liked: Rapid soothing cooling (mostly mentioned)
- Liked: Hydrating non-sticky (often mentioned)
- Liked: Generous essence (sometimes noted)
- Liked: Gentle exfoliation (sometimes noted)
- Liked: High adherence (sometimes noted)
- Disliked: High price point (rarely noted)
- Disliked: Ineffective on acne (rarely noted)
- Disliked: Pad texture rough (rarely noted)
- Disliked: Strong scent (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using your soothing toner 3 times a week and move to daily use if your skin tolerates it.
- Apply your soothing toner after cleansing, and before your moisturizer or SPF.
- Gently press 2-3 drops of the soothing toner into your skin. Let it absorb for a minute before moving to the next step.
- Apply the soothing toner on clean and slightly damp skin to help with absorption. This helps keep your skin feeling fresh and balanced.
- Avoid the sensitive eye area during application. Do a patch test before your first use.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### How well does medicube Exosome Cica Calming Pad work for combination skin?

This soothing toner offers moderate care for your combination skin by calming redness and keeping oily shine under control. While it works safely without harsh ingredients, top-rated products for this skin type need a richer mix of targeted soothing extracts and deep hydration to truly balance both dry and oily areas.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37377400/)

### Which ingredients make this toner a good fit for combination skin?

Exosome Cica and Niacinamide make this toner a good fit by helping calm redness while managing oily shine and hydration. A better fit for combination skin needs more targeted soothing ingredients and stronger hydrating benefits to fully balance dry and oily areas without irritation.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37377400/)

### What do Exosomes do for combination skin?

Exosomes help balance combination skin by supporting tissue repair, calming irritation, and strengthening the skin barrier in both dry and oily areas. They may help improve hydration while keeping inflammation under control.
Sources: [Pharmaceutics, 2025](https://pubmed.ncbi.nlm.nih.gov/40430891/), [Cells, 2020](https://pubmed.ncbi.nlm.nih.gov/32392899/)

### What does Tea Tree Oil do for combination skin?

Tea tree oil helps balance combination skin by controlling excess oil and calming redness without feeling too heavy. It is unlikely to cause irritation when used properly, and it targets blemish-prone areas while keeping the skin clear and smooth.
Sources: [International Journal of Cosmetic Science, 2022](https://pubmed.ncbi.nlm.nih.gov/34986500/), [Clinical Microbiology Reviews, 2006](https://pubmed.ncbi.nlm.nih.gov/16418522/)

### Where does this toner go in a skincare routine for combination skin?

This soothing toner fits into a combination skin routine as a hydrating step in the morning after cleansing, and as a cleansing step in the evening before treatments and moisturizers. A product of this type needs calming ingredients like Exosome Cica and Niacinamide to help soothe redness and balance oily shine.

### Can I use this toner with retinol, and in what order?

You can use this toner before retinol in your evening routine, as it is unlikely to irritate your skin. A soothing toner of this type works best for combination skin when it also provides extra balancing and pore-refining ingredients to manage both oily and dry areas.

### How often should I use this toner?

You can start using this soothing toner once a week as an exfoliating step, and then carefully use it more often if your combination skin tolerates it well and you see good results. It offers moderate soothing while helping calm redness and reducing oily shine without irritation.

### Can this toner clog pores, cause breakouts or purging for combination skin?

This toner is unlikely to clog pores or cause breakouts for your combination skin because it has no harsh ingredients and includes Niacinamide to help balance oil. To properly care for combination skin, a product of this type needs soothing and hydrating ingredients that manage oily shine without heavy oils.

## Alternatives for combination skin

- [belif Problem Solution Toner](https://lovi.care/skincare/au/p/belif/problem-solution-toner/for/combination-skin) — Superior fit — A$47.96 at Amazon
- [Medicube Super Cica Pad](https://lovi.care/skincare/au/p/medicube/super-cica-pad/for/combination-skin) — Superior fit — A$49.50 at Amazon
- [COSRX Cica Toner](https://lovi.care/skincare/au/p/cosrx/cica-toner/for/combination-skin) — High fit — A$24.78 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — A$73.61 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/au/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — A$22.99 at Amazon
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/au/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — A$30.99 at Amazon

## Where to buy

- Amazon.com.au: A$49.50 (https://www.amazon.com.au/dp/B0DFG4MRC9?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Exosome Cica, Tree, Niacinamide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/exosome-cica-calming-pad/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/exosome-cica-calming-pad/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/exosome-cica-calming-pad/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/medicube/exosome-cica-calming-pad/for/combination-skin
- France: https://lovi.care/skincare/fr/p/medicube/exosome-cica-calming-pad/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/medicube/exosome-cica-calming-pad/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/exosome-cica-calming-pad/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/medicube/exosome-cica-calming-pad/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/exosome-cica-calming-pad/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/medicube/exosome-cica-calming-pad/for/combination-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/medicube/exosome-cica-calming-pad/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/exosome-cica-calming-pad/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/exosome-cica-calming-pad/for/combination-skin