# Medicube Collagen Niacinamide Jelly Cream for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [Medicube](https://lovi.care/skincare/au/brands/medicube)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/au/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Excellent for your normal skin, this formulation leverages niacinamide and collagen to provide superior hydration and stimulate collagen production, effectively addressing your concerns with wrinkles and fine lines.
- The inclusion of Cynanchum Atratum Extract and Althaea Rosea Flower Extract further enhances its suitability by offering soothing benefits, complementing the primary ingredients for overall skin health.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of beneficial soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Collagen, Niacinamide, Hydrolyzed Collagen, Water-Soluble Collagen, Squalane

## What the research says

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen. ([Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/))
- Self-assembled cubic liquid crystalline nanoparticles loaded with paeonol reduced skin irritation compared to commercial ointment, serving as a promising transdermal delivery system. ([Medical Science Monitor, 2015](https://pubmed.ncbi.nlm.nih.gov/26517086/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Based on a very large amount of data, this moisturizer is highly regarded for providing an immediate radiant glow and significant hydration, attributed to its unique cooling jelly texture. Some users find the finish to be sticky or tacky, and a portion of reviews suggest it performs better as a night mask compared to a daytime product.

- Liked: Glass skin glow (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Disliked: Sticky/tacky finish (often mentioned)
- Liked: Cooling jelly texture (sometimes noted)
- Liked: Plumping/firming (sometimes noted)
- Disliked: Absorption issues (sometimes noted)
- Disliked: Breakouts/irritation (rarely noted)
- Disliked: Fragrance/scent (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Medicube Collagen Niacinamide Jelly Cream a great fit for mature skin?

This cream is a great fit for mature skin because it uses niacinamide and collagen to deeply hydrate and smooth out fine lines and wrinkles. It is very gentle and unlikely to cause irritation while helping to keep your skin looking firm and youthful.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/), [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### Which ingredients make this cream a good fit for mature skin?

Collagen and niacinamide make this cream a great fit for mature skin by providing deep moisture and helping smooth out wrinkles and fine lines. Squalane and plant extracts further support skin health by keeping it soft and calm with a very low risk of irritation.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/), [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### What does Collagen do for mature skin?

Collagen helps smooth mature skin by reducing wrinkles, improving hydration, and keeping the skin firm and plump. It is a weak fit for your skin, so a product of this type needs added hyaluronic acid, antioxidants, and peptides to properly nourish and support aging skin.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/), [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this cream go in a skincare routine for mature skin?

This moisturizing treatment goes in your morning and evening routines after your toner and before your sunscreen or final moisturizer. It is very unlikely to cause irritation and helps keep your skin soft and smooth while addressing fine lines.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first and following it with this moisturizer. This combination helps keep your skin hydrated and may reduce dryness while supporting anti-aging care.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/)

### How often should I use this cream?

You can use this moisturizing treatment daily to help keep mature skin hydrated and smooth. Regular application supports a healthy skin barrier and is unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to cause breakouts or irritation for mature skin, as it has a very safe profile with gentle, soothing ingredients and no harsh additives. Reviewers rarely report any breakouts or irritation.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because its formula features a very safe profile and soothing botanical extracts that are unlikely to irritate delicate areas. Regular application helps smooth fine lines and improves hydration on thinner skin.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2014](https://pubmed.ncbi.nlm.nih.gov/24056055/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for mature skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/au/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/mature-skin) — Superior fit — A$32.25 at Amazon
- [Sulwhasoo Ginseng Renewing Cream Ex](https://lovi.care/skincare/au/p/sulwhasoo/ginseng-renewing-cream-ex/for/mature-skin) — Superior fit — A$349.82 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/au/p/cosrx/advanced-snail-96-mucin-power-essence/for/mature-skin) — Superior fit — A$18.90 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — A$73.61 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/au/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — A$37.00 at Amazon
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/au/p/pyunkang-yul/deep-cleansing-oil/for/mature-skin) — Superior fit — A$30.99 at Amazon

## Where to buy

- Amazon.com.au: A$38.30 (https://www.amazon.com.au/dp/B0CM2PPNMW?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Propanediol, Dipropylene Glycol, Butylene Glycol, Methylpropanediol, Diethoxyethyl Succinate, Ethoxydiglycol, Ammonium Acryloyldimethyltaurate Beheneth-25 Methacrylate Crosspolymer, Niacinamide, Trehalose, 1,2-Hexanediol, Chlorella Vulgaris Extract, Collagen, Hydrolyzed Collagen, Cynanchum Atratum Extract, Althaea Rosea Flower Extract, Water-Soluble Collagen, Allium Sativum Bulb Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Bertholletia Excelsa Seed Extract, Brassica Oleracea Italica Extract, Camellia Sinensis Seed Extract, Salmon Egg Extract, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Spinach Leaf Extract, Blueberry Fruit Extract, Wine Extract, Polyglyceryl-10 Isostearate, Tromethamine, Glucose, Polyglyceryl-10 Oleate, Ethylhexylglycerin, Fructooligosaccharides, Fructose, Adenosine, Sodium Phytate, Cyanocobalamin, Tocopherol, Pullulan, Glycerin, Hydroxypropyltrimonium Hyaluronate, Squalane, Soluble Proteoglycan, Hydrolyzed Elastin, Sodium Dna, Carbomer, Xanthan Gum, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- France: https://lovi.care/skincare/fr/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/collagen-niacinamide-jelly-cream/for/mature-skin