# La Roche-Posay Redermic R for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [La Roche-Posay](https://lovi.care/skincare/au/brands/la-roche-posay)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate anti-aging benefits for your normal skin, as retinol and retinyl linoleate work to smooth texture and minimize fine lines, while adenosine boosts ECM synthesis.
- Glycerin and sodium hyaluronate provide general hydration, which is supportive but not directly targeted at your redness and irritation.
- The product is safe for your sensitive skin, with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/oily-acne-prone-skin): High

## Key ingredients

Retinol, Sodium Hyaluronate, Glycerin, Adenosine, Capryloyl Salicylic Acid

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))
- Capryloyl salicylic acid peel reduced fine lines, wrinkles, and hyperpigmentation comparably to glycolic acid peel in 44 female volunteers, with no statistically significant differences between the two treatments. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146601/))
- Combining a salicylic acid and lipohydroxy acid facial serum and mask improved closed comedones and acne severity significantly more than serum alone in adults with acne over 8 weeks, with no adverse reactions reported. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36999489/))
- Parity was demonstrated between an OTC BPO 5.5% formulation with lipohydroxy acid and tretinoin cream 0.025% versus prescription clindamycin 1%-BPO 5% gel and tretinoin cream 0.025% in participants with mild to moderate acne vulgaris at 12 weeks. ([Cutis, 2012](https://pubmed.ncbi.nlm.nih.gov/22838094/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))

## What reviewers say

Users find this product to be an effective starter retinol, particularly for sensitive skin, with many reporting improvements in skin texture and fine lines without irritation. Some users note that it may be too mild for deeper wrinkles and requires consistent long-term use for significant results.

- Liked: Smoothes texture (mostly mentioned)
- Liked: Gentle on skin (often mentioned)
- Liked: Reduces lines (often mentioned)
- Liked: Lightweight formula (sometimes noted)
- Disliked: Mild/Slow results (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Liked: Helps acne/marks (rarely noted)
- Disliked: Drying effect (rarely noted)
- Disliked: Small packaging (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Redermic R work for sensitive skin?

La Roche-Posay Redermic R offers moderate anti-aging benefits for sensitive skin, helping to smooth texture and keep skin hydrated while remaining safe without harsh irritants. However, a treatment for sensitive skin needs ingredients like niacinamide or snail secretion filtrate to actively calm redness and irritation.

### Which ingredients make this treatment a good fit for sensitive skin?

Retinol, retinyl linoleate, and adenosine help smooth texture and fine lines on sensitive skin, while glycerin and sodium hyaluronate provide general hydration. This treatment works for your skin, though a treatment of this type needs ingredients that target redness and irritation, such as niacinamide and snail secretion filtrate.

### What does Retinol do for sensitive skin?

Retinol is generally too harsh for sensitive skin and may cause stinging, scaling, and irritation. A product for this skin needs gentle ingredients that smooth and calm without causing redness.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Toxicology Letters, 2003](https://pubmed.ncbi.nlm.nih.gov/14615068/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does this treatment go in a skincare routine for sensitive skin?

This treatment goes in your evening routine, applied after your soothing toner and before your moisturizer. Putting treatments in the evening keeps things simple and helps avoid extra sun sensitivity.

### Can I use it with vitamin C, and in what order?

You can use this treatment with vitamin C by applying vitamin C in your morning routine and this treatment at night, as using both at the same time may cause too much tingling on sensitive skin. To better calm and protect sensitive skin, a product of this type needs soothing and barrier-repairing ingredients like ceramides and niacinamide.

### How often should I use this treatment?

Apply this treatment in the evening as part of your weekly routine, starting just once a week. If your skin feels comfortable and you see good results, you may carefully use it more often. To better care for sensitive skin, this type of product also needs soothing and calming ingredients to keep it comfortable.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can it clog pores, cause breakouts or purging for sensitive skin?

La Roche-Posay Redermic R is unlikely to clog pores or cause breakouts on sensitive skin, though the retinol it contains may cause mild purging when you first start using it. This product needs soothing ingredients and gentle hydrators like ceramides and niacinamide to help keep sensitive skin calm and comfortable.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — A$50.60 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/au/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — A$27.50 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/au/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — A$34.41 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/au/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — A$73.61 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/au/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — A$54.00 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/au/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — A$24.49 at Amazon

## Where to buy

- Amazon.com.au: A$35.69 (https://www.amazon.com.au/dp/B00EED8G2S?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Isostearyl Neopentanoate, Glycerin, Octyldodecanol, Propylene Glycol, Pentylene Glycol, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, Cetearyl Alcohol, Glycine Soja Oil, Soybean Oil, Triethanolamine, Isohexadecane, Sodium Hyaluronate, Retinol, Retinyl Linoleate, Adenosine, Capryloyl Salicylic Acid, Caprylyl Glycol, Polysorbate 80, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/redermic-r/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/redermic-r/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/redermic-r/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/redermic-r/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/redermic-r/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/redermic-r/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/redermic-r/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/redermic-r/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/redermic-r/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/redermic-r/for/sensitive-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/redermic-r/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/redermic-r/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/redermic-r/for/sensitive-skin