# ISDIN Flavo-C Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Australia.

Brand: [ISDIN](https://lovi.care/skincare/au/brands/isdin)
Category: [Serums and treatments](https://lovi.care/skincare/au/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your combination skin, the ascorbic acid and lactic acid provide antioxidant activity and mild exfoliation, respectively, which are beneficial for your skin type.
- The serum offers excellent antioxidant protection and skin brightening due to the presence of ascorbic acid and ginkgo biloba leaf extract, though these ingredients are mostly supportive for your primary concerns of acne, blemishes, and breakouts.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/oily-acne-prone-skin): High

## Key ingredients

Ascorbic Acid, Ginkgo Biloba, Lactic Acid, Propylene Glycol

## What the research says

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Vitamin C mesotherapy produced a significant and earlier reduction in gingival pigmentation and higher patient satisfaction compared to topical gel in twenty healthy non-smokers with hyperpigmented gingiva, with both methods reducing the mean area fraction of melanin-forming cells at 6 months without causing pain. ([Clinical Oral Investigations, 2021](https://pubmed.ncbi.nlm.nih.gov/33966113/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26203268/))
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Topical application of Ginkgo biloba cream for two weeks reduced wrinkles and improved skin shape, texture, and tautness in human volunteers compared to baseline. ([Drug Development and Industrial Pharmacy, 2023](https://pubmed.ncbi.nlm.nih.gov/37074796/))
- Application of a cream containing lactic acid 12% and pramoxine HCl 1% significantly improved skin dryness, hydration, and itch compared with a nontreated control in 24 women with a history of dry itchy skin. ([Cutis, 2004](https://pubmed.ncbi.nlm.nih.gov/15027519/))
- Topical 12% ammonium lactate produced a significant sparing of epidermal and dermal atrophy induced by clobetasol propionate in human volunteers, without influencing the corticosteroid's bioavailability or antiinflammatory properties. ([Journal of the American Academy of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1597538/))
- A lactic acid/ceramide lotion significantly improved skin moisturization and desquamation compared to no treatment in women with dry, rough skin on the anterior shins. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33178384/))
- Treatment with a combination of propylene glycol, ethanol, water, and shampoo was found effective, easy to use, and cosmetically attractive with no observed side effects in patients with dandruff. ([Cutis, 1988](https://pubmed.ncbi.nlm.nih.gov/2970946/))
- A moisturizer containing glycerol and propylene glycol reduced transepidermal water loss, decreased epidermal thickness, increased stratum corneum thickness, and reduced dermal inflammatory infiltrate compared to untreated disrupted skin in six healthy beagle dogs. ([Veterinary Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32628309/))

## What reviewers say

This serum is highly regarded for its ability to brighten dull skin, reduce hyperpigmentation, and smooth fine lines, making it particularly effective for mature, dehydrated, or sun-damaged complexions. The formula is frequently praised for being lightweight and fast-absorbing, and for providing significant hydration. A small number of users with sensitive skin have reported experiencing irritation or redness.

- Liked: Brightens skin tone (often mentioned)
- Liked: Hydrates and smooths (often mentioned)
- Liked: Lightweight, fast-absorbing (sometimes noted)
- Disliked: Frustrating packaging (rarely noted)
- Disliked: Irritates sensitive skin (rarely noted)
- Disliked: Unpleasant smell (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes ISDIN Flavo-C a great fit for acne-prone skin?

ISDIN Flavo-C Serum is a great fit because ascorbic acid and lactic acid provide antioxidant activity and mild exfoliation that benefit your skin. It also has a safe profile with no harsh ingredients, meaning it is unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Which ingredients make this serum a good fit for acne-prone skin?

Ascorbic Acid and Lactic Acid make this serum a great fit for acne-prone skin by providing antioxidant activity and mild exfoliation. The formula has an excellent safety profile and is unlikely to cause irritation.

### What does Vitamin C do for acne-prone skin?

Vitamin C helps brighten skin, smooth out uneven tones, and fade dark spots left behind by breakouts. It is also packed with antioxidants that may help protect acne-prone skin from everyday environmental stress.
Sources: [Journal of Drugs in Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/39231081/)

### What does Ginkgo Biloba Extract do for acne-prone skin?

Ginkgo biloba extract helps calm red, irritated skin and fights the oxidative stress often linked to breakouts. It helps reduce inflammation and works well alongside antibacterial ingredients to clear up acne-prone skin.
Sources: [RSC Medicinal Chemistry, 2024](https://pubmed.ncbi.nlm.nih.gov/39149101/), [Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27621660/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine for acne-prone skin, placed after cleansing and before moisturizing. Using it at night provides extra safety around sun exposure, while its gentle exfoliating ingredients help brighten the skin and keep pores clear without causing irritation.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the serum in the morning and saving your retinol for the evening routine. This serum is a great fit for your acne-prone skin because the ascorbic acid and lactic acid provide antioxidant activity and mild exfoliation, while keeping your skin calm and safe from harsh irritation.

### How often should I use this serum?

This serum is used in the evening once a week to start, and people who tolerate it well and see good results can carefully use it more often. The product has an excellent safety profile with no risks of irritation.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to clog pores or cause breakouts on acne-prone skin because it contains no harsh or prohibited ingredients that trigger irritation. It helps brighten your skin and provides antioxidant protection, while the mild exfoliation supports a smooth feel.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/au/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — A$16.95 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — A$52.32 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/au/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — A$50.60 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/au/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — A$13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/au/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — A$34.66 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/au/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — A$24.00 at Amazon

## Where to buy

- Amazon.com.au: A$30.99 (https://www.amazon.com.au/dp/B0947C56TC?tag=lovi-care-web-product-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Propylene Glycol, Water, Ginkgo Biloba Leaf Extract, Ascorbic Acid, Polysorbate 20, 2-Hexanediol, Polysorbate 80, Phenoxyethanol, Lactic Acid, Sodium Hydroxide, Ginkgo Biloba
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/isdin/flavo-c-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/isdin/flavo-c-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/isdin/flavo-c-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/isdin/flavo-c-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/isdin/flavo-c-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/isdin/flavo-c-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/isdin/flavo-c-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/isdin/flavo-c-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/isdin/flavo-c-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/acne-prone-skin (this page)
- Singapore: https://lovi.care/skincare/sg/p/isdin/flavo-c-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/isdin/flavo-c-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/isdin/flavo-c-serum/for/acne-prone-skin